Rattus norvegicus

0 known processes

Ptpn23

protein tyrosine phosphatase, non-receptor type 23

(Aliases: HD-PTP,Ptp-Td14)

Ptpn23 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.059
cellular amino acid metabolic process GO:0006520 107 0.059
organic acid metabolic process GO:0006082 292 0.059
intracellular signal transduction GO:0035556 314 0.052
regulation of rna biosynthetic process GO:2001141 381 0.049
carboxylic acid metabolic process GO:0019752 289 0.048
regulation of multicellular organismal development GO:2000026 376 0.047
oxoacid metabolic process GO:0043436 290 0.047
amine metabolic process GO:0009308 38 0.045
regulation of cell differentiation GO:0045595 320 0.045
neurological system process GO:0050877 219 0.043
regulation of phosphate metabolic process GO:0019220 349 0.042
cellular ketone metabolic process GO:0042180 51 0.040
regulation of cellular amino acid metabolic process GO:0006521 2 0.039
protein phosphorylation GO:0006468 345 0.039
cellular response to endogenous stimulus GO:0071495 377 0.038
regulation of cell proliferation GO:0042127 359 0.036
nucleic acid templated transcription GO:0097659 379 0.035
cellular amine metabolic process GO:0044106 38 0.034
regulation of cellular ketone metabolic process GO:0010565 27 0.034
regulation of intracellular signal transduction GO:1902531 218 0.033
regulation of rna metabolic process GO:0051252 391 0.032
macromolecular complex subunit organization GO:0043933 339 0.032
Fly
regulation of cellular amine metabolic process GO:0033238 8 0.031
regulation of phosphorylation GO:0042325 248 0.031
immune system process GO:0002376 204 0.031
Fly
regulation of neurogenesis GO:0050767 247 0.031
cellular response to stress GO:0033554 269 0.030
positive regulation of response to stimulus GO:0048584 285 0.030
Fly
cellular component assembly GO:0022607 360 0.030
Fly
regulation of nervous system development GO:0051960 264 0.029
circulatory system development GO:0072359 134 0.029
positive regulation of protein phosphorylation GO:0001934 135 0.028
single organism intracellular transport GO:1902582 166 0.028
Human
transcription from rna polymerase ii promoter GO:0006366 252 0.028
neuron differentiation GO:0030182 368 0.027
positive regulation of rna metabolic process GO:0051254 203 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.026
rna metabolic process GO:0016070 406 0.025
response to decreased oxygen levels GO:0036293 237 0.025
regulation of cellular component organization GO:0051128 368 0.025
Human
positive regulation of cell communication GO:0010647 271 0.025
Fly
response to nutrient GO:0007584 248 0.025
regulation of apoptotic process GO:0042981 335 0.025
single organism biosynthetic process GO:0044711 342 0.025
response to hypoxia GO:0001666 231 0.025
cellular component biogenesis GO:0044085 368 0.025
Fly
regulation of molecular function GO:0065009 398 0.024
cardiovascular system development GO:0072358 134 0.024
regulation of neuron differentiation GO:0045664 208 0.024
regulation of transcription dna templated GO:0006355 374 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
metal ion transport GO:0030001 289 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
response to ethanol GO:0045471 162 0.023
cellular response to organonitrogen compound GO:0071417 197 0.023
cation transport GO:0006812 382 0.023
regulation of programmed cell death GO:0043067 341 0.022
response to metal ion GO:0010038 253 0.022
response to oxygen levels GO:0070482 265 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
transcription dna templated GO:0006351 377 0.022
intracellular transport GO:0046907 185 0.022
Human
neuron development GO:0048666 286 0.022
response to inorganic substance GO:0010035 377 0.021
reproduction GO:0000003 245 0.021
negative regulation of neurogenesis GO:0050768 78 0.021
response to other organism GO:0051707 220 0.021
Fly
positive regulation of gene expression GO:0010628 244 0.021
transmembrane transport GO:0055085 412 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
apoptotic process GO:0006915 381 0.020
positive regulation of nervous system development GO:0051962 178 0.020
regulation of kinase activity GO:0043549 117 0.020
response to peptide GO:1901652 292 0.020
regulation of signal transduction GO:0009966 318 0.020
Fly
aging GO:0007568 241 0.020
response to bacterium GO:0009617 200 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.020
cell projection organization GO:0030030 302 0.020
Human
regulation of protein modification process GO:0031399 194 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
regulation of cell projection organization GO:0031344 175 0.020
cation transmembrane transport GO:0098655 263 0.020
response to peptide hormone GO:0043434 278 0.019
cellular chemical homeostasis GO:0055082 247 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
homeostatic process GO:0042592 331 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
rna biosynthetic process GO:0032774 380 0.019
response to nutrient levels GO:0031667 370 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.018
regulation of ion transport GO:0043269 245 0.018
positive regulation of molecular function GO:0044093 230 0.018
neuron projection development GO:0031175 273 0.018
regulation of cell development GO:0060284 263 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
Human
female pregnancy GO:0007565 122 0.018
regulation of catalytic activity GO:0050790 304 0.018
organelle organization GO:0006996 266 0.018
Fly
regulation of nucleic acid templated transcription GO:1903506 380 0.018
programmed cell death GO:0012501 392 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
regulation of protein metabolic process GO:0051246 289 0.018
divalent inorganic cation transport GO:0072511 134 0.018
multi organism reproductive process GO:0044703 262 0.018
response to acid chemical GO:0001101 222 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
regulation of protein phosphorylation GO:0001932 183 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
cellular homeostasis GO:0019725 252 0.017
response to extracellular stimulus GO:0009991 380 0.017
negative regulation of developmental process GO:0051093 125 0.017
response to estrogen GO:0043627 232 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
Human
protein oligomerization GO:0051259 191 0.017
regulation of system process GO:0044057 208 0.017
positive regulation of cell death GO:0010942 184 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
gland development GO:0048732 155 0.016
multicellular organism reproduction GO:0032504 233 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
ion transmembrane transport GO:0034220 365 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
single organism reproductive process GO:0044702 297 0.016
central nervous system development GO:0007417 311 0.016
lipid metabolic process GO:0006629 283 0.016
response to growth factor GO:0070848 189 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
cell cell signaling GO:0007267 335 0.016
reproductive process GO:0022414 372 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
secretion GO:0046903 307 0.016
organic acid biosynthetic process GO:0016053 83 0.016
cell morphogenesis GO:0000902 142 0.016
Human
cellular component morphogenesis GO:0032989 155 0.016
Human
positive regulation of cell development GO:0010720 176 0.015
chemical homeostasis GO:0048878 292 0.015
growth GO:0040007 165 0.015
Fly
mitotic spindle organization GO:0007052 2 0.015
defense response GO:0006952 194 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
organic substance catabolic process GO:1901575 316 0.015
Human
purine containing compound metabolic process GO:0072521 253 0.015
developmental process involved in reproduction GO:0003006 159 0.015
action potential GO:0001508 54 0.015
negative regulation of cell communication GO:0010648 158 0.015
regulation of transferase activity GO:0051338 123 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
response to cytokine GO:0034097 215 0.014
regulation of secretion by cell GO:1903530 208 0.014
positive regulation of developmental process GO:0051094 283 0.014
eye morphogenesis GO:0048592 4 0.014
muscle system process GO:0003012 115 0.014
regulation of membrane potential GO:0042391 110 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
calcium ion transport GO:0006816 131 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
negative regulation of cell development GO:0010721 82 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
organophosphate biosynthetic process GO:0090407 143 0.013
spindle organization GO:0007051 2 0.013
Fly
small molecule biosynthetic process GO:0044283 124 0.013
head development GO:0060322 247 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
brain development GO:0007420 247 0.013
peptidyl amino acid modification GO:0018193 126 0.013
response to purine containing compound GO:0014074 126 0.013
positive regulation of ion transport GO:0043270 94 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
lysosomal transport GO:0007041 8 0.013
response to estradiol GO:0032355 164 0.013
response to carbohydrate GO:0009743 183 0.013
response to monosaccharide GO:0034284 159 0.013
organophosphate metabolic process GO:0019637 370 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
locomotion GO:0040011 237 0.013
Human
regeneration GO:0031099 163 0.013
protein complex biogenesis GO:0070271 263 0.013
Fly
jak stat cascade GO:0007259 26 0.013
tissue development GO:0009888 252 0.013
regulation of immune system process GO:0002682 123 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
carboxylic acid biosynthetic process GO:0046394 83 0.013
response to ketone GO:1901654 182 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
synaptic transmission GO:0007268 235 0.012
metal ion homeostasis GO:0055065 186 0.012
macromolecule localization GO:0033036 252 0.012
cellular response to peptide GO:1901653 133 0.012
lipid biosynthetic process GO:0008610 128 0.012
multi multicellular organism process GO:0044706 138 0.012
negative regulation of signaling GO:0023057 157 0.012
single organism organelle organization GO:1902589 180 0.012
Fly
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
nucleotide metabolic process GO:0009117 279 0.012
reproductive structure development GO:0048608 128 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
protein complex assembly GO:0006461 263 0.012
Fly
positive regulation of transport GO:0051050 245 0.012
Human
protein complex subunit organization GO:0071822 302 0.012
Fly
localization of cell GO:0051674 202 0.012
Human
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
neuron projection morphogenesis GO:0048812 122 0.012
monovalent inorganic cation transport GO:0015672 172 0.011
cell motility GO:0048870 202 0.011
Human
response to glucocorticoid GO:0051384 223 0.011
anterior posterior pattern specification GO:0009952 1 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
salivary gland development GO:0007431 3 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
regulation of protein kinase activity GO:0045859 105 0.011
positive regulation of protein modification process GO:0031401 142 0.011
heart morphogenesis GO:0003007 3 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
Fly
response to organophosphorus GO:0046683 102 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
regulation of cellular localization GO:0060341 263 0.011
Human
multicellular organism growth GO:0035264 1 0.011
response to lipopolysaccharide GO:0032496 191 0.011
gastrulation GO:0007369 2 0.011
cell part morphogenesis GO:0032990 123 0.011
Human
regulation of neuron projection development GO:0010975 161 0.011
cytoplasmic transport GO:0016482 115 0.011
Human
protein localization GO:0008104 191 0.011
nucleoside metabolic process GO:0009116 179 0.011
negative regulation of transport GO:0051051 136 0.011
adult locomotory behavior GO:0008344 4 0.011
positive regulation of signaling GO:0023056 270 0.011
Fly
response to external biotic stimulus GO:0043207 221 0.011
Fly
cation homeostasis GO:0055080 195 0.011
positive regulation of immunoglobulin production GO:0002639 4 0.011
muscle tissue morphogenesis GO:0060415 1 0.011
multicellular organismal signaling GO:0035637 44 0.010
oxidation reduction process GO:0055114 304 0.010
response to toxic substance GO:0009636 133 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
innate immune response GO:0045087 35 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
response to vitamin GO:0033273 131 0.010
single organism catabolic process GO:0044712 283 0.010
ion homeostasis GO:0050801 212 0.010
negative regulation of cell death GO:0060548 229 0.010
cellular response to alcohol GO:0097306 87 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
response to camp GO:0051591 91 0.010
cell adhesion GO:0007155 110 0.010
Human
negative regulation of nervous system development GO:0051961 79 0.010
cell cycle GO:0007049 101 0.010
Fly
ras protein signal transduction GO:0007265 29 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
axon development GO:0061564 96 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
reproductive system development GO:0061458 128 0.010

Ptpn23 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.062
nervous system disease DOID:863 0 0.062
sensory system disease DOID:0050155 0 0.015
central nervous system disease DOID:331 0 0.015
musculoskeletal system disease DOID:17 0 0.014