Rattus norvegicus

0 known processes

Srpx

sushi-repeat-containing protein, X-linked

(Aliases: Drs,MGC105430)

Srpx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to extracellular stimulus GO:0009991 380 0.331
immune system process GO:0002376 204 0.200
tissue development GO:0009888 252 0.180
ossification GO:0001503 70 0.156
cellular response to endogenous stimulus GO:0071495 377 0.150
response to wounding GO:0009611 254 0.145
localization of cell GO:0051674 202 0.137
cellular component assembly GO:0022607 360 0.130
Rat
reproductive process GO:0022414 372 0.128
positive regulation of programmed cell death GO:0043068 157 0.128
cellular component movement GO:0006928 248 0.122
protein complex biogenesis GO:0070271 263 0.118
response to nutrient levels GO:0031667 370 0.111
positive regulation of response to stimulus GO:0048584 285 0.108
protein complex assembly GO:0006461 263 0.106
protein complex subunit organization GO:0071822 302 0.101
organ morphogenesis GO:0009887 75 0.098
cellular component biogenesis GO:0044085 368 0.093
Rat
response to corticosteroid GO:0031960 235 0.086
skeletal system development GO:0001501 41 0.080
aging GO:0007568 241 0.078
macromolecular complex subunit organization GO:0043933 339 0.078
regulation of multicellular organismal development GO:2000026 376 0.077
Rat
response to nutrient GO:0007584 248 0.075
appendage morphogenesis GO:0035107 4 0.073
cellular response to growth factor stimulus GO:0071363 162 0.072
macromolecular complex assembly GO:0065003 273 0.071
single organism biosynthetic process GO:0044711 342 0.068
positive regulation of signal transduction GO:0009967 175 0.065
response to glucocorticoid GO:0051384 223 0.065
tube development GO:0035295 89 0.064
cardiovascular system development GO:0072358 134 0.061
response to oxygen levels GO:0070482 265 0.059
oxoacid metabolic process GO:0043436 290 0.058
positive regulation of cell communication GO:0010647 271 0.058
organic acid metabolic process GO:0006082 292 0.057
cation homeostasis GO:0055080 195 0.056
wound healing GO:0042060 122 0.056
positive regulation of signaling GO:0023056 270 0.056
response to estrogen GO:0043627 232 0.055
rna metabolic process GO:0016070 406 0.053
response to vitamin GO:0033273 131 0.053
response to peptide hormone GO:0043434 278 0.052
regulation of phosphate metabolic process GO:0019220 349 0.051
cellular response to peptide hormone stimulus GO:0071375 120 0.050
cellular response to external stimulus GO:0071496 118 0.050
regulation of cell proliferation GO:0042127 359 0.050
regulation of cellular localization GO:0060341 263 0.049
eye morphogenesis GO:0048592 4 0.049
regulation of rna metabolic process GO:0051252 391 0.049
gastrulation GO:0007369 2 0.048
cation transport GO:0006812 382 0.047
regulation of rna biosynthetic process GO:2001141 381 0.046
locomotion GO:0040011 237 0.046
cellular metal ion homeostasis GO:0006875 172 0.045
response to peptide GO:1901652 292 0.045
intracellular signal transduction GO:0035556 314 0.045
embryonic skeletal system development GO:0048706 3 0.045
cellular response to hormone stimulus GO:0032870 247 0.044
neurological system process GO:0050877 219 0.042
bone development GO:0060348 25 0.042
formation of primary germ layer GO:0001704 1 0.042
cell migration GO:0016477 197 0.041
immune response GO:0006955 104 0.040
rna biosynthetic process GO:0032774 380 0.040
response to ketone GO:1901654 182 0.040
positive regulation of secretion by cell GO:1903532 128 0.040
response to mechanical stimulus GO:0009612 134 0.039
neuronal action potential GO:0019228 35 0.039
regulation of signal transduction GO:0009966 318 0.039
cartilage development GO:0051216 22 0.039
negative regulation of multicellular organismal process GO:0051241 203 0.039
central nervous system development GO:0007417 311 0.038
positive regulation of cell death GO:0010942 184 0.038
cellular response to oxygen containing compound GO:1901701 386 0.038
response to biotic stimulus GO:0009607 226 0.038
positive regulation of phosphate metabolic process GO:0045937 262 0.038
blood circulation GO:0008015 183 0.038
ion homeostasis GO:0050801 212 0.038
carboxylic acid metabolic process GO:0019752 289 0.037
kidney development GO:0001822 67 0.037
protein heterooligomerization GO:0051291 89 0.036
regeneration GO:0031099 163 0.036
single organism catabolic process GO:0044712 283 0.036
chemical homeostasis GO:0048878 292 0.036
protein phosphorylation GO:0006468 345 0.036
multicellular organism reproduction GO:0032504 233 0.036
anatomical structure morphogenesis GO:0009653 298 0.035
multi multicellular organism process GO:0044706 138 0.035
circulatory system development GO:0072359 134 0.035
epithelium development GO:0060429 96 0.035
response to molecule of bacterial origin GO:0002237 194 0.035
transmission of nerve impulse GO:0019226 42 0.035
regulation of cell motility GO:2000145 131 0.034
regulation of phosphorylation GO:0042325 248 0.034
positive regulation of secretion GO:0051047 140 0.034
response to purine containing compound GO:0014074 126 0.033
vasculature development GO:0001944 70 0.033
response to acid chemical GO:0001101 222 0.033
regulation of response to stress GO:0080134 126 0.033
positive regulation of cellular component movement GO:0051272 102 0.032
regulation of hormone levels GO:0010817 187 0.032
response to decreased oxygen levels GO:0036293 237 0.032
positive regulation of transport GO:0051050 245 0.032
receptor mediated endocytosis GO:0006898 42 0.032
response to cytokine GO:0034097 215 0.032
endochondral bone growth GO:0003416 3 0.032
cartilage development involved in endochondral bone morphogenesis GO:0060351 3 0.032
multicellular organismal reproductive process GO:0048609 233 0.031
negative regulation of response to stimulus GO:0048585 155 0.031
metal ion transport GO:0030001 289 0.031
response to alkaloid GO:0043279 132 0.031
negative regulation of cell proliferation GO:0008285 119 0.030
cellular response to extracellular stimulus GO:0031668 73 0.030
cell motility GO:0048870 202 0.030
response to external biotic stimulus GO:0043207 221 0.030
female pregnancy GO:0007565 122 0.029
cellular response to peptide GO:1901653 133 0.029
multi organism reproductive process GO:0044703 262 0.028
response to hyperoxia GO:0055093 45 0.028
anatomical structure formation involved in morphogenesis GO:0048646 83 0.028
growth GO:0040007 165 0.028
programmed cell death GO:0012501 392 0.028
cellular homeostasis GO:0019725 252 0.028
regulation of apoptotic process GO:0042981 335 0.027
response to glucose GO:0009749 136 0.027
cellular response to nitrogen compound GO:1901699 210 0.027
catabolic process GO:0009056 351 0.027
positive regulation of cell motility GO:2000147 97 0.027
apoptotic process GO:0006915 381 0.026
regulation of anatomical structure morphogenesis GO:0022603 141 0.026
cellular response to organonitrogen compound GO:0071417 197 0.026
embryo development GO:0009790 49 0.026
single organism intracellular transport GO:1902582 166 0.026
positive regulation of locomotion GO:0040017 102 0.026
defense response GO:0006952 194 0.026
negative regulation of cell death GO:0060548 229 0.025
respiratory system development GO:0060541 45 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.025
response to estradiol GO:0032355 164 0.025
response to hypoxia GO:0001666 231 0.025
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
cellular response to lipid GO:0071396 201 0.025
cellular chemical homeostasis GO:0055082 247 0.025
response to hexose GO:0009746 144 0.024
regulation of locomotion GO:0040012 148 0.024
head development GO:0060322 247 0.024
neural crest cell differentiation GO:0014033 2 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
cellular amine metabolic process GO:0044106 38 0.024
reproduction GO:0000003 245 0.024
nucleotide metabolic process GO:0009117 279 0.024
peptidyl amino acid modification GO:0018193 126 0.024
secretion by cell GO:0032940 248 0.024
response to tumor necrosis factor GO:0034612 56 0.024
regulation of secretion GO:0051046 224 0.024
transcription dna templated GO:0006351 377 0.024
response to other organism GO:0051707 220 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
positive regulation of developmental process GO:0051094 283 0.023
Rat
organic substance catabolic process GO:1901575 316 0.023
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.022
regulation of cell differentiation GO:0045595 320 0.022
regulation of blood pressure GO:0008217 83 0.022
positive regulation of blood coagulation GO:0030194 4 0.022
single organism reproductive process GO:0044702 297 0.022
nucleic acid templated transcription GO:0097659 379 0.022
response to toxic substance GO:0009636 133 0.022
action potential GO:0001508 54 0.022
tissue morphogenesis GO:0048729 22 0.021
regulation of programmed cell death GO:0043067 341 0.021
homeostatic process GO:0042592 331 0.021
negative regulation of metabolic process GO:0009892 331 0.021
regulation of cell migration GO:0030334 128 0.021
regulation of secretion by cell GO:1903530 208 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
negative regulation of signal transduction GO:0009968 83 0.021
response to amino acid GO:0043200 75 0.021
response to bacterium GO:0009617 200 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
cellular ion homeostasis GO:0006873 184 0.020
positive regulation of molecular function GO:0044093 230 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
Rat
cellular response to nutrient levels GO:0031669 60 0.020
regulation of cellular component movement GO:0051270 150 0.020
multicellular organismal signaling GO:0035637 44 0.020
cellular response to nutrient GO:0031670 30 0.019
response to camp GO:0051591 91 0.019
extracellular structure organization GO:0043062 13 0.019
cellular response to vitamin e GO:0071306 3 0.019
regulation of protein metabolic process GO:0051246 289 0.019
forebrain development GO:0030900 98 0.019
negative regulation of cell communication GO:0010648 158 0.019
circulatory system process GO:0003013 183 0.019
regulation of immune response GO:0050776 55 0.019
regulation of immune system process GO:0002682 123 0.019
response to ethanol GO:0045471 162 0.019
regulation of system process GO:0044057 208 0.019
eye development GO:0001654 50 0.019
brain development GO:0007420 247 0.019
response to indole 3 methanol GO:0071680 2 0.019
hormone metabolic process GO:0042445 69 0.019
g protein coupled receptor signaling pathway GO:0007186 242 0.019
protein oligomerization GO:0051259 191 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
vesicle mediated transport GO:0016192 181 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
single organism organelle organization GO:1902589 180 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
response to carbohydrate GO:0009743 183 0.018
macromolecule localization GO:0033036 252 0.018
renal system development GO:0072001 67 0.018
response to metal ion GO:0010038 253 0.018
response to progesterone GO:0032570 48 0.018
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.018
vasculogenesis GO:0001570 3 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
response to lipopolysaccharide GO:0032496 191 0.018
response to growth factor GO:0070848 189 0.018
cellular response to mechanical stimulus GO:0071260 48 0.018
organophosphate catabolic process GO:0046434 148 0.018
sequestering of metal ion GO:0051238 9 0.017
response to nicotine GO:0035094 51 0.017
protein localization GO:0008104 191 0.017
intracellular transport GO:0046907 185 0.017
maintenance of location GO:0051235 17 0.017
regulation of membrane potential GO:0042391 110 0.017
response to temperature stimulus GO:0009266 94 0.017
collagen fibril organization GO:0030199 1 0.017
myelination GO:0042552 39 0.017
sequestering of calcium ion GO:0051208 8 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
metal ion homeostasis GO:0055065 186 0.017
response to monosaccharide GO:0034284 159 0.017
vascular process in circulatory system GO:0003018 96 0.016
reproductive structure development GO:0048608 128 0.016
regulation of transcription dna templated GO:0006355 374 0.016
development of primary sexual characteristics GO:0045137 107 0.016
ensheathment of neurons GO:0007272 40 0.016
digestive system development GO:0055123 41 0.016
regulation of cytokine production GO:0001817 56 0.016
biological adhesion GO:0022610 110 0.016
gland development GO:0048732 155 0.016
ras protein signal transduction GO:0007265 29 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
intramembranous ossification GO:0001957 1 0.016
regulation of stem cell differentiation GO:2000736 2 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
secretion GO:0046903 307 0.016
reproductive system development GO:0061458 128 0.016
cellular cation homeostasis GO:0030003 180 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
connective tissue development GO:0061448 33 0.016
potassium ion transport GO:0006813 97 0.016
positive regulation of cell migration GO:0030335 96 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
Rat
multicellular organismal catabolic process GO:0044243 2 0.015
regulation of cellular component organization GO:0051128 368 0.015
Rat
amine metabolic process GO:0009308 38 0.015
tissue remodeling GO:0048771 40 0.015
cellular response to tumor necrosis factor GO:0071356 46 0.015
divalent metal ion transport GO:0070838 132 0.015
inflammatory response GO:0006954 150 0.015
muscle tissue development GO:0060537 58 0.015
blood vessel development GO:0001568 69 0.015
aromatic compound catabolic process GO:0019439 168 0.015
gonad development GO:0008406 104 0.015
protein homooligomerization GO:0051260 91 0.015
cellular catabolic process GO:0044248 295 0.015
osteoblast differentiation GO:0001649 26 0.015
urogenital system development GO:0001655 78 0.015
calcium ion homeostasis GO:0055074 162 0.015
ovulation cycle GO:0042698 67 0.015
lipid biosynthetic process GO:0008610 128 0.015
skeletal system morphogenesis GO:0048705 12 0.015
negative regulation of heart growth GO:0061117 3 0.015
response to increased oxygen levels GO:0036296 45 0.015
lung development GO:0030324 43 0.015
cytoplasmic transport GO:0016482 115 0.015
regulation of nucleic acid templated transcription GO:1903506 380 0.014
anterior posterior pattern specification GO:0009952 1 0.014
organophosphate metabolic process GO:0019637 370 0.014
cellular response to vitamin GO:0071295 21 0.014
limb morphogenesis GO:0035108 4 0.014
lipid metabolic process GO:0006629 283 0.014
response to inorganic substance GO:0010035 377 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
sex differentiation GO:0007548 113 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
regulation of cellular component biogenesis GO:0044087 86 0.014
Rat
sulfur amino acid metabolic process GO:0000096 9 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
camp metabolic process GO:0046058 63 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
negative regulation of innate immune response GO:0045824 4 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
establishment of protein localization GO:0045184 141 0.013
developmental process involved in reproduction GO:0003006 159 0.013
insulin like growth factor receptor signaling pathway GO:0048009 3 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
axon ensheathment GO:0008366 40 0.013
regulation of body fluid levels GO:0050878 90 0.013
response to retinoic acid GO:0032526 63 0.013
neuron differentiation GO:0030182 368 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
oxidation reduction process GO:0055114 304 0.013
regulation of metal ion transport GO:0010959 118 0.013
tube morphogenesis GO:0035239 23 0.013
response to fibroblast growth factor GO:0071774 29 0.013
cellular response to acid chemical GO:0071229 75 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
cellular response to alcohol GO:0097306 87 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
small molecule biosynthetic process GO:0044283 124 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
negative regulation of response to external stimulus GO:0032102 37 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.012
cellular macromolecule localization GO:0070727 122 0.012
camera type eye morphogenesis GO:0048593 2 0.012
negative regulation of fibrinolysis GO:0051918 2 0.012
sensory organ development GO:0007423 74 0.012
extracellular matrix organization GO:0030198 13 0.012
growth plate cartilage development GO:0003417 2 0.012
regulation of molecular function GO:0065009 398 0.012
regulation of cell development GO:0060284 263 0.012
endomembrane system organization GO:0010256 48 0.012
regulation of epithelial cell proliferation GO:0050678 49 0.012
carboxylic acid biosynthetic process GO:0046394 83 0.012
digestive tract development GO:0048565 39 0.012
protein heterotrimerization GO:0070208 2 0.012
positive regulation of the force of heart contraction by norepinephrine GO:0003061 1 0.012
regulation of intracellular transport GO:0032386 65 0.012
protein processing GO:0016485 68 0.012
regulation of protein modification process GO:0031399 194 0.012
regulation of embryonic development GO:0045995 2 0.012
calcium ion transport GO:0006816 131 0.012
renin secretion into blood stream GO:0002001 1 0.012
cell cell signaling GO:0007267 335 0.012
Rat
muscle structure development GO:0061061 87 0.012
protein transport GO:0015031 132 0.012
glial cell development GO:0021782 19 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
negative regulation of immune system process GO:0002683 39 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
positive regulation of cytoplasmic transport GO:1903651 32 0.011
regulation of mapk cascade GO:0043408 116 0.011
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.011
embryonic pattern specification GO:0009880 1 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
coenzyme metabolic process GO:0006732 86 0.011
male gamete generation GO:0048232 99 0.011
striated muscle tissue development GO:0014706 58 0.011
cellular response to stress GO:0033554 269 0.011
regulation of anatomical structure size GO:0090066 135 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
cellular carbohydrate metabolic process GO:0044262 72 0.011
proteolysis GO:0006508 175 0.011
muscle cell differentiation GO:0042692 52 0.011
blood vessel morphogenesis GO:0048514 58 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
positive regulation of immune response GO:0050778 42 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
artery development GO:0060840 3 0.011
regulation of epithelial to mesenchymal transition GO:0010717 2 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
fibrinolysis GO:0042730 2 0.011
muscle organ development GO:0007517 50 0.011
peptide metabolic process GO:0006518 32 0.011
regulation of hormone secretion GO:0046883 106 0.011
defense response to gram negative bacterium GO:0050829 3 0.010
regulation of growth GO:0040008 105 0.010
response to fluoride GO:1902617 3 0.010
negative regulation of homeostatic process GO:0032845 47 0.010
negative regulation of response to wounding GO:1903035 23 0.010
negative regulation of signaling GO:0023057 157 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
glucose metabolic process GO:0006006 52 0.010
purine containing compound metabolic process GO:0072521 253 0.010
tissue regeneration GO:0042246 36 0.010
luteolysis GO:0001554 5 0.010
negative regulation of cellular metabolic process GO:0031324 281 0.010
morphogenesis of an epithelium GO:0002009 20 0.010
organic hydroxy compound metabolic process GO:1901615 115 0.010
extracellular fibril organization GO:0043206 1 0.010
plasminogen activation GO:0031639 2 0.010
nucleotide catabolic process GO:0009166 139 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
monosaccharide metabolic process GO:0005996 61 0.010
hormone secretion GO:0046879 115 0.010
rho protein signal transduction GO:0007266 11 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
positive regulation of hormone secretion GO:0046887 65 0.010
embryonic hindlimb morphogenesis GO:0035116 2 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010

Srpx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.150
musculoskeletal system disease DOID:17 0 0.150
cardiovascular system disease DOID:1287 0 0.030
nervous system disease DOID:863 0 0.029
bone disease DOID:0080001 0 0.020
connective tissue disease DOID:65 0 0.020
artery disease DOID:0050828 0 0.015
vascular disease DOID:178 0 0.015
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012
bone development disease DOID:0080006 0 0.011
central nervous system disease DOID:331 0 0.010