Rattus norvegicus

11 known processes

Msln

mesothelin

Msln biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic anion transport GO:0015711 132 0.125
response to peptide GO:1901652 292 0.103
regulation of cell proliferation GO:0042127 359 0.079
response to lipopolysaccharide GO:0032496 191 0.074
positive regulation of cell proliferation GO:0008284 249 0.074
single organism biosynthetic process GO:0044711 342 0.069
regulation of phosphorus metabolic process GO:0051174 349 0.068
cellular response to endogenous stimulus GO:0071495 377 0.066
response to biotic stimulus GO:0009607 226 0.063
cellular response to oxygen containing compound GO:1901701 386 0.063
organic acid transport GO:0015849 116 0.061
positive regulation of multicellular organismal process GO:0051240 387 0.057
response to peptide hormone GO:0043434 278 0.056
oxoacid metabolic process GO:0043436 290 0.055
reproductive process GO:0022414 372 0.055
aging GO:0007568 241 0.055
cellular response to hormone stimulus GO:0032870 247 0.053
nitrogen compound transport GO:0071705 229 0.053
transmembrane transport GO:0055085 412 0.052
regulation of phosphate metabolic process GO:0019220 349 0.052
organic substance catabolic process GO:1901575 316 0.051
organic acid metabolic process GO:0006082 292 0.050
nucleobase containing small molecule metabolic process GO:0055086 316 0.050
regulation of system process GO:0044057 208 0.049
macromolecule localization GO:0033036 252 0.049
oxidation reduction process GO:0055114 304 0.048
single organism reproductive process GO:0044702 297 0.046
cellular catabolic process GO:0044248 295 0.046
response to estrogen GO:0043627 232 0.046
negative regulation of multicellular organismal process GO:0051241 203 0.045
cation transmembrane transport GO:0098655 263 0.044
response to nutrient levels GO:0031667 370 0.044
response to molecule of bacterial origin GO:0002237 194 0.042
response to hypoxia GO:0001666 231 0.041
small molecule biosynthetic process GO:0044283 124 0.041
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
organophosphate metabolic process GO:0019637 370 0.039
regulation of molecular function GO:0065009 398 0.038
neuron differentiation GO:0030182 368 0.038
rna biosynthetic process GO:0032774 380 0.038
cellular amine metabolic process GO:0044106 38 0.036
protein phosphorylation GO:0006468 345 0.036
head development GO:0060322 247 0.036
carboxylic acid metabolic process GO:0019752 289 0.036
reproduction GO:0000003 245 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.035
positive regulation of transport GO:0051050 245 0.035
regulation of membrane potential GO:0042391 110 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
regulation of catalytic activity GO:0050790 304 0.034
cellular chemical homeostasis GO:0055082 247 0.033
anion transport GO:0006820 178 0.033
ion transmembrane transport GO:0034220 365 0.033
amino acid transport GO:0006865 70 0.033
response to oxygen levels GO:0070482 265 0.032
amine metabolic process GO:0009308 38 0.031
catabolic process GO:0009056 351 0.031
cellular component biogenesis GO:0044085 368 0.031
chemical homeostasis GO:0048878 292 0.031
carboxylic acid transport GO:0046942 115 0.031
circulatory system process GO:0003013 183 0.030
regeneration GO:0031099 163 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
protein transport GO:0015031 132 0.030
intracellular transport GO:0046907 185 0.030
g protein coupled receptor signaling pathway GO:0007186 242 0.030
homeostatic process GO:0042592 331 0.030
hepaticobiliary system development GO:0061008 90 0.029
neuronal action potential GO:0019228 35 0.029
positive regulation of phosphate metabolic process GO:0045937 262 0.029
organonitrogen compound biosynthetic process GO:1901566 167 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.029
cation transport GO:0006812 382 0.029
macromolecular complex assembly GO:0065003 273 0.029
response to other organism GO:0051707 220 0.028
regulation of secretion GO:0051046 224 0.028
response to extracellular stimulus GO:0009991 380 0.028
regulation of protein phosphorylation GO:0001932 183 0.028
blood circulation GO:0008015 183 0.028
positive regulation of cellular protein metabolic process GO:0032270 167 0.027
metal ion homeostasis GO:0055065 186 0.027
monovalent inorganic cation transport GO:0015672 172 0.027
regulation of blood circulation GO:1903522 110 0.026
nucleotide metabolic process GO:0009117 279 0.026
response to acid chemical GO:0001101 222 0.026
response to corticosteroid GO:0031960 235 0.026
apoptotic process GO:0006915 381 0.026
response to mechanical stimulus GO:0009612 134 0.026
positive regulation of cell death GO:0010942 184 0.026
regulation of response to stress GO:0080134 126 0.026
response to wounding GO:0009611 254 0.026
regulation of cell differentiation GO:0045595 320 0.026
ion homeostasis GO:0050801 212 0.025
inorganic cation transmembrane transport GO:0098662 202 0.025
single organism intracellular transport GO:1902582 166 0.025
amide transport GO:0042886 105 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
regulation of phosphorylation GO:0042325 248 0.025
action potential GO:0001508 54 0.024
intracellular signal transduction GO:0035556 314 0.024
response to glucocorticoid GO:0051384 223 0.024
positive regulation of gene expression GO:0010628 244 0.024
protein oligomerization GO:0051259 191 0.024
single organism catabolic process GO:0044712 283 0.024
regulation of programmed cell death GO:0043067 341 0.024
response to bacterium GO:0009617 200 0.024
metal ion transport GO:0030001 289 0.023
positive regulation of protein phosphorylation GO:0001934 135 0.023
regulation of nervous system development GO:0051960 264 0.023
purine containing compound metabolic process GO:0072521 253 0.023
response to ketone GO:1901654 182 0.023
purine nucleotide metabolic process GO:0006163 229 0.023
cellular response to abiotic stimulus GO:0071214 85 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
central nervous system development GO:0007417 311 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
regulation of apoptotic process GO:0042981 335 0.023
ribose phosphate metabolic process GO:0019693 235 0.022
muscle system process GO:0003012 115 0.022
regulation of protein kinase activity GO:0045859 105 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
cellular lipid metabolic process GO:0044255 208 0.022
response to cytokine GO:0034097 215 0.022
heart process GO:0003015 57 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
purine containing compound catabolic process GO:0072523 138 0.022
regulation of protein modification process GO:0031399 194 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
positive regulation of response to stimulus GO:0048584 285 0.022
cellular response to organonitrogen compound GO:0071417 197 0.022
learning or memory GO:0007611 90 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
programmed cell death GO:0012501 392 0.021
cellular calcium ion homeostasis GO:0006874 160 0.021
cellular ketone metabolic process GO:0042180 51 0.021
brain development GO:0007420 247 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
negative regulation of cell death GO:0060548 229 0.021
regulation of heart contraction GO:0008016 48 0.021
organic acid biosynthetic process GO:0016053 83 0.021
cellular response to stress GO:0033554 269 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
lipid transport GO:0006869 61 0.020
cation homeostasis GO:0055080 195 0.020
protein complex biogenesis GO:0070271 263 0.020
heart contraction GO:0060047 57 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
response to decreased oxygen levels GO:0036293 237 0.020
monocarboxylic acid metabolic process GO:0032787 152 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
cellular ion homeostasis GO:0006873 184 0.020
positive regulation of apoptotic process GO:0043065 154 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
protein homooligomerization GO:0051260 91 0.020
cellular response to lipid GO:0071396 201 0.019
nucleoside metabolic process GO:0009116 179 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
positive regulation of protein modification process GO:0031401 142 0.019
regulation of purine nucleotide metabolic process GO:1900542 115 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
regulation of hormone levels GO:0010817 187 0.018
epithelial cell proliferation GO:0050673 54 0.018
proteolysis GO:0006508 175 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
response to organophosphorus GO:0046683 102 0.018
cellular cation homeostasis GO:0030003 180 0.018
peptide transport GO:0015833 97 0.018
aromatic compound catabolic process GO:0019439 168 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
liver development GO:0001889 90 0.018
cellular component assembly GO:0022607 360 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
cardiovascular system development GO:0072358 134 0.018
regulation of protein metabolic process GO:0051246 289 0.018
multicellular organismal signaling GO:0035637 44 0.017
protein localization GO:0008104 191 0.017
multi organism reproductive process GO:0044703 262 0.017
positive regulation of developmental process GO:0051094 283 0.017
organelle organization GO:0006996 266 0.017
carboxylic acid biosynthetic process GO:0046394 83 0.017
purine ribonucleotide catabolic process GO:0009154 136 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.017
multicellular organism reproduction GO:0032504 233 0.017
inflammatory response GO:0006954 150 0.017
secretion by cell GO:0032940 248 0.017
organic hydroxy compound transport GO:0015850 77 0.017
organ regeneration GO:0031100 101 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
lipid metabolic process GO:0006629 283 0.017
regulation of kinase activity GO:0043549 117 0.017
negative regulation of molecular function GO:0044092 133 0.016
cellular protein localization GO:0034613 122 0.016
cellular homeostasis GO:0019725 252 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
response to inorganic substance GO:0010035 377 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
neuron projection development GO:0031175 273 0.016
cell cell signaling GO:0007267 335 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
response to ethanol GO:0045471 162 0.016
gland development GO:0048732 155 0.016
regulation of transferase activity GO:0051338 123 0.016
response to metal ion GO:0010038 253 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
cytoskeleton organization GO:0007010 111 0.016
regulation of rna metabolic process GO:0051252 391 0.016
negative regulation of metabolic process GO:0009892 331 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
response to insulin GO:0032868 133 0.016
muscle contraction GO:0006936 88 0.016
signal transduction by phosphorylation GO:0023014 144 0.015
negative regulation of phosphorus metabolic process GO:0010563 80 0.015
response to estradiol GO:0032355 164 0.015
negative regulation of neuron differentiation GO:0045665 62 0.015
organophosphate catabolic process GO:0046434 148 0.015
regulation of muscle system process GO:0090257 79 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
developmental process involved in reproduction GO:0003006 159 0.015
positive regulation of molecular function GO:0044093 230 0.015
cellular component movement GO:0006928 248 0.015
response to alkaloid GO:0043279 132 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
immune system process GO:0002376 204 0.015
protein complex subunit organization GO:0071822 302 0.015
response to external biotic stimulus GO:0043207 221 0.015
neurological system process GO:0050877 219 0.015
protein complex assembly GO:0006461 263 0.015
regulation of protein localization GO:0032880 81 0.015
positive regulation of blood circulation GO:1903524 65 0.015
cellular macromolecule localization GO:0070727 122 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
regulation of neurogenesis GO:0050767 247 0.015
growth GO:0040007 165 0.015
sulfur compound metabolic process GO:0006790 70 0.015
peptidyl amino acid modification GO:0018193 126 0.015
negative regulation of cell communication GO:0010648 158 0.015
positive regulation of protein metabolic process GO:0051247 178 0.014
regulation of signal transduction GO:0009966 318 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
positive regulation of cell communication GO:0010647 271 0.014
positive regulation of signaling GO:0023056 270 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
negative regulation of developmental process GO:0051093 125 0.014
endocytosis GO:0006897 84 0.014
regulation of protein transport GO:0051223 68 0.014
nucleic acid templated transcription GO:0097659 379 0.014
response to purine containing compound GO:0014074 126 0.014
response to testosterone GO:0033574 55 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
rna metabolic process GO:0016070 406 0.013
vesicle mediated transport GO:0016192 181 0.013
ras protein signal transduction GO:0007265 29 0.013
sexual reproduction GO:0019953 148 0.013
regulation of response to wounding GO:1903034 69 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
regulation of anatomical structure size GO:0090066 135 0.013
response to nutrient GO:0007584 248 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
lipid localization GO:0010876 62 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
response to toxic substance GO:0009636 133 0.013
multicellular organism growth GO:0035264 1 0.013
negative regulation of transport GO:0051051 136 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
bmp signaling pathway GO:0030509 4 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
protein targeting GO:0006605 61 0.013
response to ammonium ion GO:0060359 71 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
regulation of synaptic transmission GO:0050804 141 0.013
regulation of muscle contraction GO:0006937 53 0.013
biological adhesion GO:0022610 110 0.013
regulation of neurological system process GO:0031644 43 0.013
circulatory system development GO:0072359 134 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
single organism cellular localization GO:1902580 102 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
eye morphogenesis GO:0048592 4 0.012
actin filament based process GO:0030029 86 0.012
nucleotide catabolic process GO:0009166 139 0.012
response to reactive oxygen species GO:0000302 120 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
monocarboxylic acid transport GO:0015718 52 0.012
vascular process in circulatory system GO:0003018 96 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
cell projection organization GO:0030030 302 0.012
response to camp GO:0051591 91 0.012
regulation of cellular localization GO:0060341 263 0.012
regulation of transcription dna templated GO:0006355 374 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
positive regulation of cell development GO:0010720 176 0.012
calcium ion homeostasis GO:0055074 162 0.012
regulation of epithelial cell proliferation GO:0050678 49 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
cellular amino acid biosynthetic process GO:0008652 32 0.012
fatty acid derivative metabolic process GO:1901568 38 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
response to cgmp GO:0070305 3 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
synaptic transmission GO:0007268 235 0.012
intracellular protein transport GO:0006886 79 0.012
heterocycle catabolic process GO:0046700 167 0.012
cell activation GO:0001775 97 0.012
regulation of cell projection organization GO:0031344 175 0.012
regulation of cellular component organization GO:0051128 368 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.012
positive regulation of signal transduction GO:0009967 175 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
positive regulation of transferase activity GO:0051347 81 0.012
cytoplasmic transport GO:0016482 115 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
transcription dna templated GO:0006351 377 0.011
peptide hormone secretion GO:0030072 84 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
response to osmotic stress GO:0006970 42 0.011
gastrulation GO:0007369 2 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
regulation of inflammatory response GO:0050727 48 0.011
regulation of cell development GO:0060284 263 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
cell growth GO:0016049 104 0.011
acid secretion GO:0046717 48 0.011
regulation of nucleotide catabolic process GO:0030811 65 0.011
nucleoside catabolic process GO:0009164 126 0.011
acute inflammatory response GO:0002526 58 0.011
response to interleukin 13 GO:0035962 3 0.011
positive regulation of catabolic process GO:0009896 78 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
positive regulation of nervous system development GO:0051962 178 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
spermatogenesis GO:0007283 99 0.010
response to monosaccharide GO:0034284 159 0.010
kidney development GO:0001822 67 0.010
neuron development GO:0048666 286 0.010
female pregnancy GO:0007565 122 0.010
establishment of protein localization GO:0045184 141 0.010
anterior posterior pattern specification GO:0009952 1 0.010
amino acid transmembrane transport GO:0003333 33 0.010
cell adhesion GO:0007155 110 0.010
cyclic nucleotide metabolic process GO:0009187 80 0.010
purine containing compound biosynthetic process GO:0072522 85 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010

Msln disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.019
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
inherited metabolic disorder DOID:655 0 0.014
sensory system disease DOID:0050155 0 0.012