Rattus norvegicus

20 known processes

Folr1

folate receptor 1 (adult)

(Aliases: Fbp1)

Folr1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.115
regulation of programmed cell death GO:0043067 341 0.115
organic acid metabolic process GO:0006082 292 0.099
tissue development GO:0009888 252 0.097
negative regulation of rna biosynthetic process GO:1902679 118 0.092
regulation of rna metabolic process GO:0051252 391 0.091
macromolecular complex assembly GO:0065003 273 0.078
gland development GO:0048732 155 0.075
eye morphogenesis GO:0048592 4 0.068
negative regulation of transcription dna templated GO:0045892 116 0.064
nucleic acid templated transcription GO:0097659 379 0.062
rna biosynthetic process GO:0032774 380 0.060
monovalent inorganic cation transport GO:0015672 172 0.059
regeneration GO:0031099 163 0.058
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.054
regulation of apoptotic process GO:0042981 335 0.053
negative regulation of cellular biosynthetic process GO:0031327 161 0.053
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.052
carboxylic acid metabolic process GO:0019752 289 0.052
camera type eye development GO:0043010 48 0.050
sodium ion transmembrane transport GO:0035725 67 0.048
reproductive system development GO:0061458 128 0.047
transcription from rna polymerase ii promoter GO:0006366 252 0.046
oxoacid metabolic process GO:0043436 290 0.045
ion homeostasis GO:0050801 212 0.045
apoptotic process GO:0006915 381 0.045
regulation of nucleic acid templated transcription GO:1903506 380 0.045
regulation of rna biosynthetic process GO:2001141 381 0.045
negative regulation of gene expression GO:0010629 199 0.045
amine metabolic process GO:0009308 38 0.044
anatomical structure morphogenesis GO:0009653 298 0.043
sensory organ development GO:0007423 74 0.043
negative regulation of nucleic acid templated transcription GO:1903507 117 0.041
cation transmembrane transport GO:0098655 263 0.041
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.039
development of primary sexual characteristics GO:0045137 107 0.039
response to extracellular stimulus GO:0009991 380 0.039
negative regulation of cellular metabolic process GO:0031324 281 0.039
protein complex assembly GO:0006461 263 0.037
cellular component assembly GO:0022607 360 0.037
head development GO:0060322 247 0.037
organ morphogenesis GO:0009887 75 0.035
cellular chemical homeostasis GO:0055082 247 0.035
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.035
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.034
protein complex biogenesis GO:0070271 263 0.033
negative regulation of biosynthetic process GO:0009890 168 0.033
cellular component biogenesis GO:0044085 368 0.032
divalent inorganic cation homeostasis GO:0072507 165 0.031
cellular response to growth factor stimulus GO:0071363 162 0.031
cell morphogenesis involved in differentiation GO:0000904 119 0.031
homeostatic process GO:0042592 331 0.030
reproductive structure development GO:0048608 128 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
negative regulation of rna metabolic process GO:0051253 123 0.029
response to wounding GO:0009611 254 0.028
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
protein complex subunit organization GO:0071822 302 0.028
cellular ketone metabolic process GO:0042180 51 0.028
cellular response to stress GO:0033554 269 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
anion transport GO:0006820 178 0.027
transcription dna templated GO:0006351 377 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
brain development GO:0007420 247 0.027
epithelial cell differentiation GO:0030855 71 0.027
cation transport GO:0006812 382 0.026
regulation of cell proliferation GO:0042127 359 0.026
response to metal ion GO:0010038 253 0.026
negative regulation of apoptotic process GO:0043066 181 0.026
immune system process GO:0002376 204 0.026
sodium ion transport GO:0006814 82 0.026
programmed cell death GO:0012501 392 0.026
central nervous system development GO:0007417 311 0.025
response to corticosteroid GO:0031960 235 0.025
negative regulation of cell death GO:0060548 229 0.025
regulation of transcription dna templated GO:0006355 374 0.025
cell morphogenesis GO:0000902 142 0.025
aging GO:0007568 241 0.024
chemical homeostasis GO:0048878 292 0.024
cation homeostasis GO:0055080 195 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
male sex differentiation GO:0046661 64 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
negative regulation of metabolic process GO:0009892 331 0.023
positive regulation of mapk cascade GO:0043410 92 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
response to acid chemical GO:0001101 222 0.022
cellular amine metabolic process GO:0044106 38 0.022
neuron projection morphogenesis GO:0048812 122 0.022
cell migration GO:0016477 197 0.022
positive regulation of rna metabolic process GO:0051254 203 0.021
gonad development GO:0008406 104 0.021
axonogenesis GO:0007409 71 0.021
transmembrane transport GO:0055085 412 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
cell projection organization GO:0030030 302 0.021
neuron development GO:0048666 286 0.020
sex differentiation GO:0007548 113 0.020
ion transmembrane transport GO:0034220 365 0.020
single organism reproductive process GO:0044702 297 0.020
rna metabolic process GO:0016070 406 0.020
defense response GO:0006952 194 0.019
organelle organization GO:0006996 266 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
regulation of molecular function GO:0065009 398 0.019
cellular response to oxygen containing compound GO:1901701 386 0.019
carboxylic acid biosynthetic process GO:0046394 83 0.018
response to growth factor GO:0070848 189 0.018
male gonad development GO:0008584 59 0.018
response to peptide hormone GO:0043434 278 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
regulation of neurogenesis GO:0050767 247 0.018
reproductive process GO:0022414 372 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
retina morphogenesis in camera type eye GO:0060042 1 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
response to toxic substance GO:0009636 133 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
axis specification GO:0009798 4 0.017
positive regulation of biosynthetic process GO:0009891 319 0.017
response to retinoic acid GO:0032526 63 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
response to inorganic substance GO:0010035 377 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
regulation of cellular component organization GO:0051128 368 0.016
cellular homeostasis GO:0019725 252 0.016
metal ion homeostasis GO:0055065 186 0.016
camera type eye morphogenesis GO:0048593 2 0.016
oligopeptide transport GO:0006857 4 0.016
cellular component morphogenesis GO:0032989 155 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
axon development GO:0061564 96 0.016
negative regulation of cell communication GO:0010648 158 0.015
intracellular signal transduction GO:0035556 314 0.015
neuron differentiation GO:0030182 368 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.015
regulation of anion transport GO:0044070 43 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
negative regulation of signal transduction GO:0009968 83 0.015
metal ion transport GO:0030001 289 0.015
positive regulation of developmental process GO:0051094 283 0.015
multi organism reproductive process GO:0044703 262 0.015
dephosphorylation GO:0016311 98 0.015
positive regulation of cell communication GO:0010647 271 0.015
cellular modified amino acid metabolic process GO:0006575 61 0.015
single organism biosynthetic process GO:0044711 342 0.015
glial cell differentiation GO:0010001 65 0.015
potassium ion transport GO:0006813 97 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
fatty acid metabolic process GO:0006631 99 0.014
organic anion transport GO:0015711 132 0.014
response to nutrient levels GO:0031667 370 0.014
cell cell signaling GO:0007267 335 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
regulation of organelle organization GO:0033043 80 0.014
eye development GO:0001654 50 0.014
neuron projection development GO:0031175 273 0.014
sexual reproduction GO:0019953 148 0.014
organ induction GO:0001759 1 0.014
regulation of locomotion GO:0040012 148 0.014
intestinal absorption GO:0050892 3 0.014
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.014
retina development in camera type eye GO:0060041 27 0.014
regulation of membrane potential GO:0042391 110 0.013
positive regulation of gene expression GO:0010628 244 0.013
positive regulation of signaling GO:0023056 270 0.013
regulation of phosphorylation GO:0042325 248 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
development of primary female sexual characteristics GO:0046545 56 0.013
ovulation cycle process GO:0022602 50 0.013
multicellular organism reproduction GO:0032504 233 0.013
positive regulation of signal transduction GO:0009967 175 0.013
female pregnancy GO:0007565 122 0.013
protein oligomerization GO:0051259 191 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
regulation of response to stress GO:0080134 126 0.013
response to vitamin GO:0033273 131 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
regulation of cell differentiation GO:0045595 320 0.013
reproduction GO:0000003 245 0.013
female gonad development GO:0008585 53 0.013
organ formation GO:0048645 3 0.013
neurological system process GO:0050877 219 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
regulation of neuron projection development GO:0010975 161 0.013
mapk cascade GO:0000165 140 0.013
epithelium development GO:0060429 96 0.013
proteolysis GO:0006508 175 0.012
heart process GO:0003015 57 0.012
cellular cation homeostasis GO:0030003 180 0.012
morphogenesis of embryonic epithelium GO:0016331 3 0.012
cellular response to external stimulus GO:0071496 118 0.012
cytoskeleton organization GO:0007010 111 0.012
monocarboxylic acid biosynthetic process GO:0072330 48 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
multi multicellular organism process GO:0044706 138 0.012
regulation of phosphate metabolic process GO:0019220 349 0.012
rhythmic process GO:0048511 156 0.012
developmental process involved in reproduction GO:0003006 159 0.012
neural crest cell development GO:0014032 2 0.012
insulin like growth factor receptor signaling pathway GO:0048009 3 0.012
sulfur compound metabolic process GO:0006790 70 0.012
negative regulation of developmental process GO:0051093 125 0.012
regulation of defense response GO:0031347 68 0.012
regulation of response to external stimulus GO:0032101 106 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
response to other organism GO:0051707 220 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
response to monosaccharide GO:0034284 159 0.011
cellular amide metabolic process GO:0043603 44 0.011
regulation of mapk cascade GO:0043408 116 0.011
development of primary male sexual characteristics GO:0046546 59 0.011
regulation of cell projection organization GO:0031344 175 0.011
mesoderm development GO:0007498 2 0.011
sensory perception GO:0007600 101 0.011
calcium ion homeostasis GO:0055074 162 0.011
transmission of nerve impulse GO:0019226 42 0.011
regulation of system process GO:0044057 208 0.011
specification of organ identity GO:0010092 2 0.011
organic acid biosynthetic process GO:0016053 83 0.011
anterior posterior pattern specification GO:0009952 1 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
response to osmotic stress GO:0006970 42 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
protein phosphorylation GO:0006468 345 0.011
regulation of immune system process GO:0002682 123 0.011
embryonic pattern specification GO:0009880 1 0.011
neuronal action potential GO:0019228 35 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
calcium ion transport GO:0006816 131 0.010
positive regulation of phosphorus metabolic process GO:0010562 262 0.010
morphogenesis of an epithelium GO:0002009 20 0.010
cellular lipid metabolic process GO:0044255 208 0.010
chemotaxis GO:0006935 66 0.010
response to oxidative stress GO:0006979 186 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
male gamete generation GO:0048232 99 0.010
establishment of protein localization GO:0045184 141 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
regulation of signal transduction GO:0009966 318 0.010
fat cell proliferation GO:0070341 2 0.010
s shaped body morphogenesis GO:0072050 2 0.010

Folr1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
nervous system disease DOID:863 0 0.046
sensory system disease DOID:0050155 0 0.028
eye and adnexa disease DOID:1492 0 0.027
musculoskeletal system disease DOID:17 0 0.023
eye disease DOID:5614 0 0.014
connective tissue disease DOID:65 0 0.011
immune system disease DOID:2914 0 0.011