Rattus norvegicus

0 known processes

Folr2

folate receptor 2 (fetal)

Folr2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to lipopolysaccharide GO:0071222 55 0.387
response to other organism GO:0051707 220 0.303
cellular response to oxygen containing compound GO:1901701 386 0.296
positive regulation of response to stimulus GO:0048584 285 0.257
fc epsilon receptor signaling pathway GO:0038095 1 0.230
cellular ion homeostasis GO:0006873 184 0.226
cellular response to biotic stimulus GO:0071216 59 0.221
regulation of immune system process GO:0002682 123 0.220
immune system process GO:0002376 204 0.215
cellular response to molecule of bacterial origin GO:0071219 56 0.205
positive regulation of immune system process GO:0002684 90 0.198
response to lipopolysaccharide GO:0032496 191 0.174
cellular chemical homeostasis GO:0055082 247 0.154
response to glucocorticoid GO:0051384 223 0.135
cellular cation homeostasis GO:0030003 180 0.135
response to corticosteroid GO:0031960 235 0.128
cytokine biosynthetic process GO:0042089 3 0.128
response to bacterium GO:0009617 200 0.126
aging GO:0007568 241 0.125
response to molecule of bacterial origin GO:0002237 194 0.122
regulation of cellular localization GO:0060341 263 0.121
homeostatic process GO:0042592 331 0.121
secretion GO:0046903 307 0.119
response to oxygen levels GO:0070482 265 0.115
response to external biotic stimulus GO:0043207 221 0.115
immune response GO:0006955 104 0.114
cytokine secretion GO:0050663 15 0.112
cation transport GO:0006812 382 0.109
positive regulation of secretion GO:0051047 140 0.104
positive regulation of secretion by cell GO:1903532 128 0.099
positive regulation of mast cell activation GO:0033005 4 0.098
regulation of leukocyte degranulation GO:0043300 6 0.095
response to extracellular stimulus GO:0009991 380 0.094
response to radiation GO:0009314 137 0.093
positive regulation of leukocyte degranulation GO:0043302 4 0.092
brain development GO:0007420 247 0.091
negative regulation of multicellular organismal process GO:0051241 203 0.090
defense response GO:0006952 194 0.088
response to toxic substance GO:0009636 133 0.088
cellular divalent inorganic cation homeostasis GO:0072503 162 0.086
acute inflammatory response to non antigenic stimulus GO:0002525 2 0.086
divalent inorganic cation homeostasis GO:0072507 165 0.084
apoptotic process GO:0006915 381 0.083
cellular metal ion homeostasis GO:0006875 172 0.082
response to vitamin GO:0033273 131 0.082
response to nutrient levels GO:0031667 370 0.080
establishment of protein localization GO:0045184 141 0.079
positive regulation of immune response GO:0050778 42 0.079
cytokine production GO:0001816 61 0.078
positive regulation of transport GO:0051050 245 0.077
response to nutrient GO:0007584 248 0.077
g protein coupled receptor signaling pathway GO:0007186 242 0.076
response to cytokine GO:0034097 215 0.076
cellular lipid metabolic process GO:0044255 208 0.075
fatty acid metabolic process GO:0006631 99 0.074
central nervous system development GO:0007417 311 0.074
cytosolic calcium ion homeostasis GO:0051480 140 0.067
cellular response to organic cyclic compound GO:0071407 202 0.066
locomotion GO:0040011 237 0.065
regulation of secretion GO:0051046 224 0.065
cation homeostasis GO:0055080 195 0.065
response to biotic stimulus GO:0009607 226 0.064
positive regulation of cytokine production GO:0001819 42 0.064
regulation of response to external stimulus GO:0032101 106 0.064
positive regulation of response to external stimulus GO:0032103 51 0.062
cellular component assembly GO:0022607 360 0.061
single organism biosynthetic process GO:0044711 342 0.061
response to metal ion GO:0010038 253 0.060
immune response regulating signaling pathway GO:0002764 19 0.060
exocytosis GO:0006887 60 0.060
mast cell mediated immunity GO:0002448 10 0.059
growth GO:0040007 165 0.059
regulation of programmed cell death GO:0043067 341 0.059
response to peptide GO:1901652 292 0.058
positive regulation of inflammatory response GO:0050729 24 0.058
granulocyte chemotaxis GO:0071621 15 0.056
programmed cell death GO:0012501 392 0.055
regulation of metal ion transport GO:0010959 118 0.054
regulation of cytokine biosynthetic process GO:0042035 3 0.052
positive regulation of locomotion GO:0040017 102 0.051
cellular response to organonitrogen compound GO:0071417 197 0.051
mast cell activation GO:0045576 15 0.050
secretion by cell GO:0032940 248 0.050
positive regulation of multicellular organismal process GO:0051240 387 0.049
positive regulation of cellular component movement GO:0051272 102 0.049
response to decreased oxygen levels GO:0036293 237 0.048
cellular response to lipid GO:0071396 201 0.048
response to amino acid GO:0043200 75 0.047
complement receptor mediated signaling pathway GO:0002430 2 0.047
positive regulation of signaling GO:0023056 270 0.047
luteolysis GO:0001554 5 0.047
response to hypoxia GO:0001666 231 0.046
anatomical structure formation involved in morphogenesis GO:0048646 83 0.045
response to ionizing radiation GO:0010212 59 0.045
cellular homeostasis GO:0019725 252 0.044
macromolecular complex assembly GO:0065003 273 0.044
wound healing GO:0042060 122 0.043
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.042
protein secretion GO:0009306 34 0.041
regulation of multicellular organismal development GO:2000026 376 0.041
localization of cell GO:0051674 202 0.041
regulation of mast cell activation involved in immune response GO:0033006 6 0.039
calcium ion homeostasis GO:0055074 162 0.039
regulation of apoptotic process GO:0042981 335 0.037
positive regulation of cell development GO:0010720 176 0.037
regulation of locomotion GO:0040012 148 0.036
ion homeostasis GO:0050801 212 0.036
negative regulation of apoptotic process GO:0043066 181 0.035
regulation of cell proliferation GO:0042127 359 0.035
response to acid chemical GO:0001101 222 0.035
response to mechanical stimulus GO:0009612 134 0.035
leukocyte degranulation GO:0043299 12 0.034
positive regulation of intracellular signal transduction GO:1902533 138 0.034
tumor necrosis factor biosynthetic process GO:0042533 1 0.034
acute inflammatory response GO:0002526 58 0.034
response to temperature stimulus GO:0009266 94 0.034
negative regulation of cell death GO:0060548 229 0.034
immune effector process GO:0002252 53 0.033
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 8 0.033
negative regulation of programmed cell death GO:0043069 183 0.033
leukocyte activation involved in immune response GO:0002366 16 0.033
response to inorganic substance GO:0010035 377 0.033
protein complex subunit organization GO:0071822 302 0.032
positive regulation of developmental process GO:0051094 283 0.032
chemical homeostasis GO:0048878 292 0.032
protein oligomerization GO:0051259 191 0.032
carboxylic acid metabolic process GO:0019752 289 0.032
response to wounding GO:0009611 254 0.032
positive regulation of defense response GO:0031349 37 0.032
leukotriene biosynthetic process GO:0019370 3 0.032
metal ion transport GO:0030001 289 0.032
regulation of signal transduction GO:0009966 318 0.032
myeloid leukocyte activation GO:0002274 36 0.031
response to estradiol GO:0032355 164 0.030
cellular component biogenesis GO:0044085 368 0.029
cell migration GO:0016477 197 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
head development GO:0060322 247 0.029
response to estrogen GO:0043627 232 0.029
regulation of cellular component movement GO:0051270 150 0.028
regulation of leukocyte differentiation GO:1902105 20 0.028
regulation of tumor necrosis factor production GO:0032680 13 0.028
cellular response to lipoteichoic acid GO:0071223 1 0.028
cellular response to cytokine stimulus GO:0071345 127 0.028
second messenger mediated signaling GO:0019932 51 0.027
regulation of protein transport GO:0051223 68 0.027
response to heat GO:0009408 60 0.027
behavior GO:0007610 205 0.027
response to interferon gamma GO:0034341 20 0.027
positive regulation of camp metabolic process GO:0030816 31 0.027
positive regulation of intracellular transport GO:0032388 39 0.027
regeneration GO:0031099 163 0.026
regulation of mast cell activation GO:0033003 9 0.026
cellular calcium ion homeostasis GO:0006874 160 0.026
single organism intracellular transport GO:1902582 166 0.025
jak stat cascade GO:0007259 26 0.025
regulation of fever generation GO:0031620 6 0.025
regulation of ion transport GO:0043269 245 0.025
regulation of molecular function GO:0065009 398 0.024
monovalent inorganic cation transport GO:0015672 172 0.024
myeloid leukocyte mediated immunity GO:0002444 12 0.024
positive regulation of response to wounding GO:1903036 34 0.024
response to transition metal nanoparticle GO:1990267 122 0.024
immune response regulating cell surface receptor signaling pathway GO:0002768 10 0.024
metal ion homeostasis GO:0055065 186 0.024
sequestering of calcium ion GO:0051208 8 0.024
response to insulin GO:0032868 133 0.024
regulated secretory pathway GO:0045055 17 0.024
cellular component movement GO:0006928 248 0.024
cellular amine metabolic process GO:0044106 38 0.023
regulation of cell differentiation GO:0045595 320 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
tumor necrosis factor production GO:0032640 13 0.023
cellular response to abiotic stimulus GO:0071214 85 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
regulation of calcium ion transport GO:0051924 77 0.023
single organism cellular localization GO:1902580 102 0.022
regulation of homeostatic process GO:0032844 101 0.022
response to gamma radiation GO:0010332 24 0.022
protein kinase c activating g protein coupled receptor signaling pathway GO:0007205 12 0.022
response to growth factor GO:0070848 189 0.022
organophosphate metabolic process GO:0019637 370 0.022
neuron death GO:0070997 127 0.022
response to activity GO:0014823 73 0.022
cellular response to insulin stimulus GO:0032869 81 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
cardiovascular system development GO:0072358 134 0.021
sequestering of metal ion GO:0051238 9 0.021
organonitrogen compound biosynthetic process GO:1901566 167 0.021
complement activation GO:0006956 11 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
insecticide metabolic process GO:0017143 4 0.020
regulation of exocytosis GO:0017157 37 0.020
positive regulation of cell motility GO:2000147 97 0.020
mast cell activation involved in immune response GO:0002279 10 0.020
nitrogen compound transport GO:0071705 229 0.020
Human Rat
positive regulation of signal transduction GO:0009967 175 0.020
amine metabolic process GO:0009308 38 0.020
response to ketone GO:1901654 182 0.020
positive regulation of leukocyte migration GO:0002687 21 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
response to vitamin a GO:0033189 36 0.019
cellular response to external stimulus GO:0071496 118 0.019
s shaped body morphogenesis GO:0072050 2 0.019
protein localization GO:0008104 191 0.019
negative regulation of myeloid cell differentiation GO:0045638 3 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 13 0.019
neurological system process GO:0050877 219 0.019
sensory perception of pain GO:0019233 73 0.019
mast cell degranulation GO:0043303 10 0.019
vesicle mediated transport GO:0016192 181 0.019
cellular response to metal ion GO:0071248 55 0.019
immune system development GO:0002520 41 0.018
response to alkaloid GO:0043279 132 0.018
cellular response to glucocorticoid stimulus GO:0071385 68 0.018
regulation of inflammatory response GO:0050727 48 0.018
response to amine GO:0014075 46 0.018
blood circulation GO:0008015 183 0.018
response to carbohydrate GO:0009743 183 0.018
inflammatory response GO:0006954 150 0.018
response to hyperoxia GO:0055093 45 0.018
positive regulation of protein transport GO:0051222 41 0.018
hematopoietic progenitor cell differentiation GO:0002244 2 0.018
positive regulation of homeostatic process GO:0032846 49 0.018
ovulation cycle GO:0042698 67 0.018
positive regulation of exocytosis GO:0045921 19 0.018
reactive oxygen species metabolic process GO:0072593 37 0.018
rhythmic process GO:0048511 156 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
positive regulation of macrophage chemotaxis GO:0010759 2 0.017
myeloid cell activation involved in immune response GO:0002275 13 0.017
positive regulation of jak stat cascade GO:0046427 19 0.017
regulation of response to wounding GO:1903034 69 0.017
regulation of neuron apoptotic process GO:0043523 83 0.017
oxoacid metabolic process GO:0043436 290 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
intracellular signal transduction GO:0035556 314 0.017
positive regulation of cell communication GO:0010647 271 0.016
protein complex biogenesis GO:0070271 263 0.016
macromolecule localization GO:0033036 252 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
cellular response to alkaloid GO:0071312 25 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
regulation of body fluid levels GO:0050878 90 0.016
camp metabolic process GO:0046058 63 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
regulation of cell migration GO:0030334 128 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
divalent metal ion transport GO:0070838 132 0.015
organelle localization GO:0051640 55 0.015
response to oxidative stress GO:0006979 186 0.015
response to ethanol GO:0045471 162 0.015
cytolysis GO:0019835 4 0.015
glial cell differentiation GO:0010001 65 0.015
organic acid metabolic process GO:0006082 292 0.015
response to camp GO:0051591 91 0.015
neuron projection development GO:0031175 273 0.015
regulation of myeloid cell differentiation GO:0045637 12 0.015
circulatory system development GO:0072359 134 0.015
potassium ion transport GO:0006813 97 0.015
cell projection organization GO:0030030 302 0.015
protein homooligomerization GO:0051260 91 0.015
response to organophosphorus GO:0046683 102 0.014
regulation of sensory perception of pain GO:0051930 29 0.014
positive regulation of leukocyte activation GO:0002696 30 0.014
regulation of system process GO:0044057 208 0.014
regulation of leukocyte activation GO:0002694 45 0.014
regulation of cell motility GO:2000145 131 0.014
activation of phospholipase c activity GO:0007202 7 0.014
positive regulation of interleukin 1 secretion GO:0050716 3 0.014
cytoplasmic transport GO:0016482 115 0.014
regulation of response to stress GO:0080134 126 0.014
response to retinoic acid GO:0032526 63 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
positive regulation of smooth muscle cell migration GO:0014911 27 0.014
cellular component maintenance GO:0043954 4 0.014
regulation of immune response GO:0050776 55 0.014
cellular response to steroid hormone stimulus GO:0071383 93 0.013
blood vessel morphogenesis GO:0048514 58 0.013
positive regulation of regulated secretory pathway GO:1903307 4 0.013
regulation of interleukin 1 beta secretion GO:0050706 3 0.013
regulation of cytokine production GO:0001817 56 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
male sex determination GO:0030238 2 0.013
gonad development GO:0008406 104 0.013
defense response to gram negative bacterium GO:0050829 3 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
tissue development GO:0009888 252 0.013
regulation of regulated secretory pathway GO:1903305 7 0.013
protein complex assembly GO:0006461 263 0.013
activation of immune response GO:0002253 26 0.013
response to peptide hormone GO:0043434 278 0.013
regulation of secretion by cell GO:1903530 208 0.013
regulation of camp metabolic process GO:0030814 43 0.012
positive regulation of cell migration GO:0030335 96 0.012
positive regulation of mast cell degranulation GO:0043306 4 0.012
regulation of neurological system process GO:0031644 43 0.012
protein transport GO:0015031 132 0.012
intracellular transport GO:0046907 185 0.012
regulation of muscle contraction GO:0006937 53 0.012
biological adhesion GO:0022610 110 0.012
regulation of intracellular transport GO:0032386 65 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
positive regulation of cytokine biosynthetic process GO:0042108 1 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
positive regulation of cell death GO:0010942 184 0.012
response to transforming growth factor beta GO:0071559 46 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
multicellular organism reproduction GO:0032504 233 0.012
regulation of cell development GO:0060284 263 0.012
positive regulation of t cell chemotaxis GO:0010820 1 0.012
regulation of protein localization GO:0032880 81 0.012
response to interleukin 1 GO:0070555 55 0.012
cellular response to stress GO:0033554 269 0.012
response to purine containing compound GO:0014074 126 0.012
regulation of cellular component organization GO:0051128 368 0.012
muscle system process GO:0003012 115 0.012
hematopoietic or lymphoid organ development GO:0048534 36 0.012
regulation of catalytic activity GO:0050790 304 0.012
divalent inorganic cation transport GO:0072511 134 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
regulation of phospholipase activity GO:0010517 12 0.011
regulation of mast cell degranulation GO:0043304 6 0.011
tumor necrosis factor superfamily cytokine production GO:0071706 13 0.011
developmental growth GO:0048589 100 0.011
regulation of acute inflammatory response GO:0002673 23 0.011
cell activation GO:0001775 97 0.011
metanephric comma shaped body morphogenesis GO:0072278 2 0.011
positive regulation of mast cell activation involved in immune response GO:0033008 4 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
positive regulation of myeloid leukocyte mediated immunity GO:0002888 4 0.011
negative regulation of developmental process GO:0051093 125 0.011
metanephric s shaped body morphogenesis GO:0072284 2 0.011
positive regulation of transcription factor import into nucleus GO:0042993 4 0.011
cell proliferation involved in heart morphogenesis GO:0061323 2 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
regulation of behavior GO:0050795 61 0.010
response to ammonium ion GO:0060359 71 0.010
neuron differentiation GO:0030182 368 0.010
regulation of heterotypic cell cell adhesion GO:0034114 2 0.010
nucleotide metabolic process GO:0009117 279 0.010
dorsal ventral pattern formation GO:0009953 4 0.010
regulation of leukocyte migration GO:0002685 24 0.010
sex differentiation GO:0007548 113 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
neuronal action potential GO:0019228 35 0.010
response to isoquinoline alkaloid GO:0014072 28 0.010

Folr2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
primary immunodeficiency disease DOID:612 0 0.015
immune system disease DOID:2914 0 0.015
musculoskeletal system disease DOID:17 0 0.014
kidney disease DOID:557 0 0.013
urinary system disease DOID:18 0 0.013
immune system cancer DOID:0060083 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011