Rattus norvegicus

34 known processes

Cort

cortistatin

Cort biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell proliferation GO:0042127 359 0.294
synaptic transmission GO:0007268 235 0.215
cellular response to organic cyclic compound GO:0071407 202 0.184
regulation of secretion by cell GO:1903530 208 0.177
positive regulation of phosphate metabolic process GO:0045937 262 0.158
regulation of signal transduction GO:0009966 318 0.147
transmembrane transport GO:0055085 412 0.139
g protein coupled receptor signaling pathway GO:0007186 242 0.133
cation transport GO:0006812 382 0.132
cell cell signaling GO:0007267 335 0.130
regulation of molecular function GO:0065009 398 0.128
secretion GO:0046903 307 0.123
regulation of hormone secretion GO:0046883 106 0.119
neuron differentiation GO:0030182 368 0.113
response to other organism GO:0051707 220 0.101
hormone secretion GO:0046879 115 0.096
anion transport GO:0006820 178 0.093
positive regulation of cell communication GO:0010647 271 0.090
positive regulation of cell proliferation GO:0008284 249 0.086
cell type specific apoptotic process GO:0097285 134 0.086
inorganic ion transmembrane transport GO:0098660 229 0.086
neurological system process GO:0050877 219 0.078
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.077
transcription dna templated GO:0006351 377 0.077
single organism reproductive process GO:0044702 297 0.076
head development GO:0060322 247 0.076
rna biosynthetic process GO:0032774 380 0.073
regulation of catalytic activity GO:0050790 304 0.071
intracellular signal transduction GO:0035556 314 0.071
defecation GO:0030421 1 0.070
cellular response to external stimulus GO:0071496 118 0.069
programmed cell death GO:0012501 392 0.068
cellular response to oxygen containing compound GO:1901701 386 0.068
apoptotic process GO:0006915 381 0.068
regulation of ion transmembrane transporter activity GO:0032412 48 0.066
response to inorganic substance GO:0010035 377 0.065
regulation of phosphorus metabolic process GO:0051174 349 0.065
cellular response to endogenous stimulus GO:0071495 377 0.065
chemical homeostasis GO:0048878 292 0.063
negative regulation of response to food GO:0032096 7 0.062
reproductive process GO:0022414 372 0.061
regulation of cellular localization GO:0060341 263 0.061
positive regulation of nucleic acid templated transcription GO:1903508 197 0.060
regulation of apoptotic process GO:0042981 335 0.060
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.060
response to nutrient levels GO:0031667 370 0.060
positive regulation of molecular function GO:0044093 230 0.060
positive regulation of catalytic activity GO:0043085 184 0.060
organelle organization GO:0006996 266 0.058
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.058
ion transmembrane transport GO:0034220 365 0.058
hormone transport GO:0009914 121 0.057
metal ion homeostasis GO:0055065 186 0.056
regulation of secretion GO:0051046 224 0.055
cellular calcium ion homeostasis GO:0006874 160 0.055
nitrogen compound transport GO:0071705 229 0.053
positive regulation of signaling GO:0023056 270 0.053
regulation of programmed cell death GO:0043067 341 0.053
single organism behavior GO:0044708 130 0.052
positive regulation of response to stimulus GO:0048584 285 0.051
homeostatic process GO:0042592 331 0.051
tissue development GO:0009888 252 0.050
sensory perception GO:0007600 101 0.050
cellular component biogenesis GO:0044085 368 0.048
ion homeostasis GO:0050801 212 0.047
positive regulation of rna metabolic process GO:0051254 203 0.047
cell morphogenesis GO:0000902 142 0.047
cardiac chamber development GO:0003205 1 0.046
regulation of intracellular signal transduction GO:1902531 218 0.046
negative regulation of gene expression GO:0010629 199 0.045
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.044
positive regulation of phosphorus metabolic process GO:0010562 262 0.044
macromolecular complex subunit organization GO:0043933 339 0.044
central nervous system development GO:0007417 311 0.044
negative regulation of programmed cell death GO:0043069 183 0.043
response to peptide GO:1901652 292 0.043
positive regulation of transcription dna templated GO:0045893 197 0.043
defense response GO:0006952 194 0.043
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.042
transcription from rna polymerase ii promoter GO:0006366 252 0.042
monovalent inorganic cation transport GO:0015672 172 0.042
response to oxidative stress GO:0006979 186 0.042
positive regulation of protein modification process GO:0031401 142 0.042
regulation of protein modification process GO:0031399 194 0.042
learning or memory GO:0007611 90 0.041
regulation of ion transmembrane transport GO:0034765 121 0.041
positive regulation of action potential GO:0045760 8 0.041
positive regulation of gene expression GO:0010628 244 0.041
neuron apoptotic process GO:0051402 88 0.041
inflammatory response GO:0006954 150 0.041
response to biotic stimulus GO:0009607 226 0.040
cellular response to stress GO:0033554 269 0.040
regulation of phosphate metabolic process GO:0019220 349 0.039
positive regulation of biosynthetic process GO:0009891 319 0.039
cellular response to tumor necrosis factor GO:0071356 46 0.039
regulation of multicellular organismal development GO:2000026 376 0.039
multicellular organismal reproductive process GO:0048609 233 0.038
positive regulation of multicellular organismal process GO:0051240 387 0.038
cellular response to organonitrogen compound GO:0071417 197 0.038
brain development GO:0007420 247 0.038
regulation of synaptic transmission GO:0050804 141 0.038
regulation of rna metabolic process GO:0051252 391 0.037
purine containing compound metabolic process GO:0072521 253 0.037
response to oxygen levels GO:0070482 265 0.037
organophosphate metabolic process GO:0019637 370 0.037
cellular lipid metabolic process GO:0044255 208 0.037
response to extracellular stimulus GO:0009991 380 0.036
response to reactive oxygen species GO:0000302 120 0.036
multi organism reproductive process GO:0044703 262 0.036
secretion by cell GO:0032940 248 0.036
protein phosphorylation GO:0006468 345 0.036
cation homeostasis GO:0055080 195 0.036
calcium ion homeostasis GO:0055074 162 0.036
glutamate receptor signaling pathway GO:0007215 43 0.035
cellular amide metabolic process GO:0043603 44 0.035
negative regulation of metabolic process GO:0009892 331 0.035
regulation of leukocyte activation GO:0002694 45 0.035
protein complex biogenesis GO:0070271 263 0.035
response to growth factor GO:0070848 189 0.035
cellular ion homeostasis GO:0006873 184 0.035
cellular homeostasis GO:0019725 252 0.034
regulation of protein metabolic process GO:0051246 289 0.034
neuropeptide signaling pathway GO:0007218 29 0.034
negative regulation of signaling GO:0023057 157 0.034
reproduction GO:0000003 245 0.034
positive regulation of cellular protein metabolic process GO:0032270 167 0.033
response to external biotic stimulus GO:0043207 221 0.033
response to bacterium GO:0009617 200 0.033
cellular cation homeostasis GO:0030003 180 0.033
regulation of membrane potential GO:0042391 110 0.033
cellular response to abiotic stimulus GO:0071214 85 0.032
response to mechanical stimulus GO:0009612 134 0.032
cell projection organization GO:0030030 302 0.032
multicellular organism reproduction GO:0032504 233 0.032
cellular chemical homeostasis GO:0055082 247 0.032
response to cytokine GO:0034097 215 0.032
positive regulation of cell development GO:0010720 176 0.031
regulation of map kinase activity GO:0043405 53 0.031
protein oligomerization GO:0051259 191 0.031
regulation of glutamate receptor signaling pathway GO:1900449 17 0.031
negative regulation of biosynthetic process GO:0009890 168 0.030
cellular component morphogenesis GO:0032989 155 0.030
response to lipopolysaccharide GO:0032496 191 0.030
regulation of cellular component organization GO:0051128 368 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.030
cell projection morphogenesis GO:0048858 123 0.030
motor neuron axon guidance GO:0008045 1 0.030
lipid metabolic process GO:0006629 283 0.030
positive regulation of hormone secretion GO:0046887 65 0.030
negative regulation of cell communication GO:0010648 158 0.029
response to wounding GO:0009611 254 0.029
negative regulation of cellular biosynthetic process GO:0031327 161 0.029
signal release GO:0023061 145 0.029
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.029
positive regulation of signal transduction GO:0009967 175 0.028
learning GO:0007612 33 0.028
positive regulation of intracellular signal transduction GO:1902533 138 0.028
macromolecular complex assembly GO:0065003 273 0.028
cellular response to lipid GO:0071396 201 0.028
protein complex assembly GO:0006461 263 0.028
reproductive structure development GO:0048608 128 0.028
cellular metal ion homeostasis GO:0006875 172 0.027
positive regulation of transport GO:0051050 245 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
nucleic acid templated transcription GO:0097659 379 0.027
response to alkaloid GO:0043279 132 0.027
neuron projection morphogenesis GO:0048812 122 0.027
neuron projection development GO:0031175 273 0.027
negative regulation of peptide hormone secretion GO:0090278 30 0.027
response to glucose GO:0009749 136 0.027
single organism organelle organization GO:1902589 180 0.027
regulation of transmembrane transporter activity GO:0022898 49 0.026
response to acid chemical GO:0001101 222 0.026
aging GO:0007568 241 0.026
mapk cascade GO:0000165 140 0.026
response to glucocorticoid GO:0051384 223 0.026
inorganic cation transmembrane transport GO:0098662 202 0.026
development of primary sexual characteristics GO:0045137 107 0.026
positive regulation of secretion by cell GO:1903532 128 0.026
negative regulation of multicellular organismal process GO:0051241 203 0.026
negative regulation of luteinizing hormone secretion GO:0033685 4 0.026
negative regulation of cell death GO:0060548 229 0.026
positive regulation of protein phosphorylation GO:0001934 135 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
positive regulation of protein metabolic process GO:0051247 178 0.025
sex differentiation GO:0007548 113 0.025
cytosolic calcium ion homeostasis GO:0051480 140 0.025
rhythmic process GO:0048511 156 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.025
regulation of transporter activity GO:0032409 50 0.025
adult locomotory behavior GO:0008344 4 0.025
rna metabolic process GO:0016070 406 0.025
cell morphogenesis involved in differentiation GO:0000904 119 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
negative regulation of signal transduction GO:0009968 83 0.025
regulation of neuron death GO:1901214 115 0.025
leukocyte activation GO:0045321 76 0.025
response to electrical stimulus GO:0051602 56 0.024
reproductive system development GO:0061458 128 0.024
small gtpase mediated signal transduction GO:0007264 36 0.024
urogenital system development GO:0001655 78 0.024
forebrain development GO:0030900 98 0.024
muscle system process GO:0003012 115 0.024
regulation of transcription dna templated GO:0006355 374 0.024
developmental process involved in reproduction GO:0003006 159 0.024
response to molecule of bacterial origin GO:0002237 194 0.023
cellular response to steroid hormone stimulus GO:0071383 93 0.023
cellular component assembly GO:0022607 360 0.023
response to corticosteroid GO:0031960 235 0.023
phospholipid metabolic process GO:0006644 61 0.023
response to nicotine GO:0035094 51 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
protein complex subunit organization GO:0071822 302 0.023
peptide transport GO:0015833 97 0.023
response to axon injury GO:0048678 59 0.023
regulation of mapk cascade GO:0043408 116 0.023
axon choice point recognition GO:0016198 2 0.022
regulation of immune system process GO:0002682 123 0.022
protein maturation GO:0051604 68 0.022
response to hypoxia GO:0001666 231 0.022
negative regulation of secretion GO:0051048 82 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
regulation of peptide hormone secretion GO:0090276 80 0.021
olfactory behavior GO:0042048 2 0.021
axon midline choice point recognition GO:0016199 2 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.021
regulation of hormone levels GO:0010817 187 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
negative regulation of hormone secretion GO:0046888 46 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
mesoderm development GO:0007498 2 0.021
neuron development GO:0048666 286 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
negative regulation of phosphate metabolic process GO:0045936 80 0.021
negative regulation of cell proliferation GO:0008285 119 0.021
regulation of cation channel activity GO:2001257 23 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.021
regulation of organelle organization GO:0033043 80 0.020
cellular amino acid metabolic process GO:0006520 107 0.020
gland development GO:0048732 155 0.020
response to monosaccharide GO:0034284 159 0.020
amide biosynthetic process GO:0043604 10 0.020
regulation of ion transport GO:0043269 245 0.020
response to heat GO:0009408 60 0.020
amine metabolic process GO:0009308 38 0.020
cellular amine metabolic process GO:0044106 38 0.020
regulation of metanephros development GO:0072215 4 0.020
regulation of anatomical structure size GO:0090066 135 0.019
response to hexose GO:0009746 144 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
smooth muscle contraction GO:0006939 37 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
muscle contraction GO:0006936 88 0.019
response to ethanol GO:0045471 162 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
g protein coupled receptor internalization GO:0002031 3 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
axon development GO:0061564 96 0.019
regulation of immune response GO:0050776 55 0.019
actin cytoskeleton organization GO:0030036 73 0.018
behavior GO:0007610 205 0.018
hormone mediated signaling pathway GO:0009755 23 0.018
nucleotide metabolic process GO:0009117 279 0.018
negative regulation of secretion by cell GO:1903531 72 0.018
fertilization GO:0009566 3 0.018
response to metal ion GO:0010038 253 0.018
immune system process GO:0002376 204 0.018
regulation of phosphorylation GO:0042325 248 0.018
positive regulation of developmental process GO:0051094 283 0.018
sexual reproduction GO:0019953 148 0.018
regulation of system process GO:0044057 208 0.018
dendrite morphogenesis GO:0048813 43 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.018
regulation of cell development GO:0060284 263 0.018
regulation of peptide secretion GO:0002791 82 0.018
metal ion transport GO:0030001 289 0.017
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.017
phasic smooth muscle contraction GO:0014821 3 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
negative regulation of transport GO:0051051 136 0.017
epithelial cell proliferation GO:0050673 54 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
response to hydrogen peroxide GO:0042542 89 0.016
development of primary female sexual characteristics GO:0046545 56 0.016
positive regulation of mapk cascade GO:0043410 92 0.016
regulation of transferase activity GO:0051338 123 0.016
response to fatty acid GO:0070542 65 0.016
dorsal ventral axon guidance GO:0033563 1 0.016
dendrite development GO:0016358 72 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
positive regulation of protein kinase activity GO:0045860 73 0.016
regulation of protein kinase activity GO:0045859 105 0.016
regulation of dendrite development GO:0050773 59 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
neuromuscular synaptic transmission GO:0007274 2 0.016
response to decreased oxygen levels GO:0036293 237 0.016
organic substance catabolic process GO:1901575 316 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
embryonic pattern specification GO:0009880 1 0.015
regulation of neuron projection development GO:0010975 161 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
negative regulation of lyase activity GO:0051350 8 0.015
peptide biosynthetic process GO:0043043 3 0.015
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
calcium ion transport GO:0006816 131 0.015
response to isoquinoline alkaloid GO:0014072 28 0.014
neuron fate commitment GO:0048663 4 0.014
regulation of nervous system development GO:0051960 264 0.014
gonad development GO:0008406 104 0.014
multi multicellular organism process GO:0044706 138 0.014
response to morphine GO:0043278 27 0.014
cognition GO:0050890 92 0.014
renal system development GO:0072001 67 0.014
positive regulation of hydrolase activity GO:0051345 86 0.014
locomotion GO:0040011 237 0.014
chemosensory behavior GO:0007635 2 0.014
lipid transport GO:0006869 61 0.014
regulation of hydrolase activity GO:0051336 143 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
cellular response to alkaloid GO:0071312 25 0.014
lipid localization GO:0010876 62 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
male gamete generation GO:0048232 99 0.014
regulation of transmembrane transport GO:0034762 122 0.014
neural crest cell migration GO:0001755 1 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
response to ammonium ion GO:0060359 71 0.013
positive regulation of transferase activity GO:0051347 81 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
somatostatin receptor signaling pathway GO:0038169 4 0.013
regulation of cell differentiation GO:0045595 320 0.013
positive regulation of kinase activity GO:0033674 77 0.013
axis specification GO:0009798 4 0.013
epithelium development GO:0060429 96 0.013
ras protein signal transduction GO:0007265 29 0.013
tube formation GO:0035148 3 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
cell part morphogenesis GO:0032990 123 0.013
cellular response to hypoxia GO:0071456 51 0.013
regulation of neurogenesis GO:0050767 247 0.013
axonogenesis GO:0007409 71 0.013
neuron death GO:0070997 127 0.013
sensory organ development GO:0007423 74 0.013
organic acid transport GO:0015849 116 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
circulatory system process GO:0003013 183 0.012
endocrine process GO:0050886 32 0.012
positive regulation of secretion GO:0051047 140 0.012
defense response to gram positive bacterium GO:0050830 2 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
organic anion transport GO:0015711 132 0.012
response to estrogen GO:0043627 232 0.012
negative regulation of nuclear division GO:0051784 1 0.012
cellular ketone metabolic process GO:0042180 51 0.012
spermatogenesis GO:0007283 99 0.012
regulation of cell projection organization GO:0031344 175 0.012
regulation of action potential GO:0098900 14 0.012
organ formation GO:0048645 3 0.012
potassium ion transport GO:0006813 97 0.012
response to carbohydrate GO:0009743 183 0.012
glucose homeostasis GO:0042593 75 0.012
protein autophosphorylation GO:0046777 66 0.012
alcohol metabolic process GO:0006066 77 0.012
blood circulation GO:0008015 183 0.012
cytoskeleton organization GO:0007010 111 0.012
sensory perception of pain GO:0019233 73 0.012
bmp signaling pathway GO:0030509 4 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
positive regulation of cellular component organization GO:0051130 200 0.011
gamete generation GO:0007276 124 0.011
positive regulation of long term synaptic potentiation GO:1900273 4 0.011
negative regulation of cell division GO:0051782 1 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
single fertilization GO:0007338 3 0.011
response to peptide hormone GO:0043434 278 0.011
regulation of nucleotide catabolic process GO:0030811 65 0.011
response to activity GO:0014823 73 0.011
response to amino acid GO:0043200 75 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
endocrine hormone secretion GO:0060986 21 0.011
protein homooligomerization GO:0051260 91 0.011
growth GO:0040007 165 0.011
cellular response to drug GO:0035690 30 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
heart development GO:0007507 72 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
activation of jak2 kinase activity GO:0042977 2 0.011
kidney development GO:0001822 67 0.011
regulation of response to food GO:0032095 11 0.011
regulation of embryonic development GO:0045995 2 0.011
mitotic cell cycle GO:0000278 49 0.011
neuromuscular process GO:0050905 2 0.011
somatostatin signaling pathway GO:0038170 4 0.011
nucleoside metabolic process GO:0009116 179 0.011
skeletal system development GO:0001501 41 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
developmental growth GO:0048589 100 0.010
peptide secretion GO:0002790 86 0.010
regulation of response to stress GO:0080134 126 0.010
peptide hormone secretion GO:0030072 84 0.010
cation transmembrane transport GO:0098655 263 0.010
regulation of blood pressure GO:0008217 83 0.010
regulation of blood circulation GO:1903522 110 0.010
embryonic axis specification GO:0000578 1 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
regulation of response to external stimulus GO:0032101 106 0.010
regulation of body fluid levels GO:0050878 90 0.010
response to tumor necrosis factor GO:0034612 56 0.010

Cort disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
gastrointestinal system disease DOID:77 0 0.019
sensory system disease DOID:0050155 0 0.016
obesity DOID:9970 0 0.015
disease of metabolism DOID:0014667 0 0.015
nutrition disease DOID:374 0 0.015
overnutrition DOID:654 0 0.015
acquired metabolic disease DOID:0060158 0 0.015