Rattus norvegicus

93 known processes

Bax

Bcl2-associated X protein

Bax biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organophosphate metabolic process GO:0019637 370 0.106
rna metabolic process GO:0016070 406 0.095
nucleoside phosphate metabolic process GO:0006753 283 0.087
cellular amino acid metabolic process GO:0006520 107 0.084
macromolecule localization GO:0033036 252 0.074
programmed cell death GO:0012501 392 0.072
purine containing compound metabolic process GO:0072521 253 0.070
regulation of phosphorus metabolic process GO:0051174 349 0.062
carboxylic acid metabolic process GO:0019752 289 0.058
carbohydrate derivative metabolic process GO:1901135 346 0.053
protein localization GO:0008104 191 0.052
arp2 3 complex mediated actin nucleation GO:0034314 2 0.051
nucleotide metabolic process GO:0009117 279 0.051
homeostatic process GO:0042592 331 0.050
anion transport GO:0006820 178 0.046
ribose phosphate metabolic process GO:0019693 235 0.045
cellular response to stress GO:0033554 269 0.045
Human
cell type specific apoptotic process GO:0097285 134 0.044
apoptotic process GO:0006915 381 0.043
cell morphogenesis GO:0000902 142 0.043
immune system process GO:0002376 204 0.041
Human
regulation of molecular function GO:0065009 398 0.040
Human Rat
regulation of cellular component organization GO:0051128 368 0.040
Human Rat
cellular protein localization GO:0034613 122 0.039
regulation of cell proliferation GO:0042127 359 0.038
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.037
nitrogen compound transport GO:0071705 229 0.037
reproduction GO:0000003 245 0.036
negative regulation of macromolecule metabolic process GO:0010605 260 0.036
Rat
regulation of catalytic activity GO:0050790 304 0.035
Human Rat
response to decreased oxygen levels GO:0036293 237 0.035
Rat
chemical homeostasis GO:0048878 292 0.034
regulation of phosphate metabolic process GO:0019220 349 0.033
anatomical structure morphogenesis GO:0009653 298 0.032
glycosyl compound metabolic process GO:1901657 182 0.032
tissue development GO:0009888 252 0.032
positive regulation of cellular component organization GO:0051130 200 0.032
Human Rat
guanosine containing compound metabolic process GO:1901068 74 0.031
cell chemotaxis GO:0060326 31 0.031
positive regulation of cell death GO:0010942 184 0.031
neuron development GO:0048666 286 0.031
response to peptide hormone GO:0043434 278 0.031
Rat
single organism organelle organization GO:1902589 180 0.030
g protein coupled receptor signaling pathway GO:0007186 242 0.030
protein phosphorylation GO:0006468 345 0.030
response to peptide GO:1901652 292 0.030
Rat
cellular component morphogenesis GO:0032989 155 0.030
ribonucleotide metabolic process GO:0009259 231 0.029
cytoskeleton organization GO:0007010 111 0.029
positive regulation of signaling GO:0023056 270 0.029
Human Rat
positive regulation of developmental process GO:0051094 283 0.029
nucleoside metabolic process GO:0009116 179 0.029
catabolic process GO:0009056 351 0.029
Human
purine nucleotide metabolic process GO:0006163 229 0.029
response to oxygen levels GO:0070482 265 0.028
Rat
gtp metabolic process GO:0046039 72 0.028
locomotion GO:0040011 237 0.028
response to growth factor GO:0070848 189 0.028
response to hypoxia GO:0001666 231 0.027
Rat
cellular homeostasis GO:0019725 252 0.027
neuron projection development GO:0031175 273 0.027
regulation of cell differentiation GO:0045595 320 0.027
nucleic acid templated transcription GO:0097659 379 0.027
intracellular signal transduction GO:0035556 314 0.027
Human
gtp catabolic process GO:0006184 71 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
response to insulin GO:0032868 133 0.026
purine nucleoside metabolic process GO:0042278 169 0.026
positive regulation of apoptotic process GO:0043065 154 0.025
purine ribonucleoside metabolic process GO:0046128 168 0.025
ion transmembrane transport GO:0034220 365 0.025
Human
eye development GO:0001654 50 0.025
localization of cell GO:0051674 202 0.025
positive regulation of cell communication GO:0010647 271 0.025
Human Rat
amine metabolic process GO:0009308 38 0.025
regulation of purine nucleotide metabolic process GO:1900542 115 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
Human
negative regulation of multicellular organismal process GO:0051241 203 0.024
response to extracellular stimulus GO:0009991 380 0.024
defense response GO:0006952 194 0.024
organelle organization GO:0006996 266 0.024
cell projection organization GO:0030030 302 0.024
ribonucleoside triphosphate catabolic process GO:0009203 122 0.023
cardiovascular system development GO:0072358 134 0.023
organic anion transport GO:0015711 132 0.023
cation homeostasis GO:0055080 195 0.023
regulation of apoptotic process GO:0042981 335 0.023
response to cytokine GO:0034097 215 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
response to carbohydrate GO:0009743 183 0.023
heterocycle catabolic process GO:0046700 167 0.023
Human
positive regulation of biosynthetic process GO:0009891 319 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
single organism biosynthetic process GO:0044711 342 0.022
cellular amine metabolic process GO:0044106 38 0.022
nucleoside phosphate catabolic process GO:1901292 140 0.022
neuron differentiation GO:0030182 368 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
oxoacid metabolic process GO:0043436 290 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
Human Rat
response to monosaccharide GO:0034284 159 0.021
positive regulation of multicellular organismal process GO:0051240 387 0.021
proteolysis GO:0006508 175 0.021
Human Rat
cellular catabolic process GO:0044248 295 0.021
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
Human
cell cycle GO:0007049 101 0.021
regulation of cellular catabolic process GO:0031329 101 0.021
Human
transcription dna templated GO:0006351 377 0.021
head development GO:0060322 247 0.021
cellular calcium ion homeostasis GO:0006874 160 0.021
negative regulation of rna biosynthetic process GO:1902679 118 0.020
aromatic compound catabolic process GO:0019439 168 0.020
Human
heart morphogenesis GO:0003007 3 0.020
guanosine containing compound catabolic process GO:1901069 71 0.020
single organism reproductive process GO:0044702 297 0.020
oxidation reduction process GO:0055114 304 0.020
negative regulation of protein metabolic process GO:0051248 114 0.020
Rat
regulation of programmed cell death GO:0043067 341 0.020
response to glucose GO:0009749 136 0.020
response to nutrient levels GO:0031667 370 0.020
calcium ion homeostasis GO:0055074 162 0.020
actin nucleation GO:0045010 2 0.019
nucleoside triphosphate metabolic process GO:0009141 144 0.019
purine nucleoside triphosphate catabolic process GO:0009146 122 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
cell motility GO:0048870 202 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
Human
regulation of immune system process GO:0002682 123 0.019
Human
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
regulation of cell projection organization GO:0031344 175 0.019
regulation of neuron apoptotic process GO:0043523 83 0.018
Human
response to oxidative stress GO:0006979 186 0.018
Rat
cellular response to growth factor stimulus GO:0071363 162 0.018
organic acid transport GO:0015849 116 0.018
single organism cellular localization GO:1902580 102 0.018
positive regulation of hydrolase activity GO:0051345 86 0.018
Human
regulation of neuron death GO:1901214 115 0.018
Human
protein transport GO:0015031 132 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
regulation of organelle organization GO:0033043 80 0.018
Human Rat
lipid metabolic process GO:0006629 283 0.018
response to inorganic substance GO:0010035 377 0.018
response to wounding GO:0009611 254 0.018
secretion GO:0046903 307 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
regulation of signal transduction GO:0009966 318 0.018
Human Rat
response to alkaloid GO:0043279 132 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
regulation of cell development GO:0060284 263 0.017
nucleotide catabolic process GO:0009166 139 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
Human
aging GO:0007568 241 0.017
Rat
positive regulation of transport GO:0051050 245 0.017
positive regulation of secretion GO:0051047 140 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
Rat
regulation of phosphorylation GO:0042325 248 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
Human
response to corticosteroid GO:0031960 235 0.017
regulation of hormone levels GO:0010817 187 0.017
response to hexose GO:0009746 144 0.016
purine containing compound catabolic process GO:0072523 138 0.016
regulation of hydrolase activity GO:0051336 143 0.016
Human Rat
cellular component biogenesis GO:0044085 368 0.016
Human
single organism intracellular transport GO:1902582 166 0.016
carboxylic acid transport GO:0046942 115 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
positive regulation of molecular function GO:0044093 230 0.016
Human
microtubule based process GO:0007017 36 0.016
cellular chemical homeostasis GO:0055082 247 0.016
cell migration GO:0016477 197 0.016
central nervous system development GO:0007417 311 0.016
regulation of transcription dna templated GO:0006355 374 0.015
protein complex biogenesis GO:0070271 263 0.015
Human
glycosyl compound catabolic process GO:1901658 126 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
Human
response to ketone GO:1901654 182 0.015
organic substance catabolic process GO:1901575 316 0.015
Human
organophosphate biosynthetic process GO:0090407 143 0.015
protein complex assembly GO:0006461 263 0.015
Human
circulatory system development GO:0072359 134 0.015
brain development GO:0007420 247 0.015
somatic stem cell division GO:0048103 2 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
regulation of multicellular organismal development GO:2000026 376 0.015
secretion by cell GO:0032940 248 0.015
cell part morphogenesis GO:0032990 123 0.015
cellular response to peptide GO:1901653 133 0.014
regulation of defense response GO:0031347 68 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
multicellular organism growth GO:0035264 1 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
Human
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
amide transport GO:0042886 105 0.014
ion homeostasis GO:0050801 212 0.014
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
organic acid metabolic process GO:0006082 292 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
response to other organism GO:0051707 220 0.013
immune response GO:0006955 104 0.013
Human
cellular cation homeostasis GO:0030003 180 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
negative regulation of gene expression GO:0010629 199 0.013
Rat
response to acid chemical GO:0001101 222 0.013
negative regulation of metabolic process GO:0009892 331 0.013
Rat
regulation of nervous system development GO:0051960 264 0.013
cellular ion homeostasis GO:0006873 184 0.013
regulation of response to stress GO:0080134 126 0.013
Human
response to organophosphorus GO:0046683 102 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
regeneration GO:0031099 163 0.013
Rat
regulation of cellular localization GO:0060341 263 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
negative regulation of cell death GO:0060548 229 0.013
Rat
macromolecular complex assembly GO:0065003 273 0.012
Human
endomembrane system organization GO:0010256 48 0.012
negative regulation of arp2 3 complex mediated actin nucleation GO:0034316 1 0.012
regulation of kinase activity GO:0043549 117 0.012
regulation of anatomical structure size GO:0090066 135 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
metal ion homeostasis GO:0055065 186 0.012
cellular ketone metabolic process GO:0042180 51 0.012
cation transport GO:0006812 382 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
cellular component assembly GO:0022607 360 0.012
Human
positive regulation of protein metabolic process GO:0051247 178 0.012
Human
purine ribonucleotide metabolic process GO:0009150 227 0.012
negative regulation of cell communication GO:0010648 158 0.012
regulation of protein polymerization GO:0032271 19 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
single organism catabolic process GO:0044712 283 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
cell cycle checkpoint GO:0000075 2 0.012
cytoplasmic transport GO:0016482 115 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
cellular lipid metabolic process GO:0044255 208 0.012
cellular protein complex assembly GO:0043623 44 0.012
regulation of apoptotic signaling pathway GO:2001233 13 0.012
Human Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
Human
neuron projection morphogenesis GO:0048812 122 0.012
axis specification GO:0009798 4 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
neuron death GO:0070997 127 0.012
Human
organonitrogen compound biosynthetic process GO:1901566 167 0.012
amino acid transport GO:0006865 70 0.012
response to ethanol GO:0045471 162 0.011
Rat
regulation of neurogenesis GO:0050767 247 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
growth GO:0040007 165 0.011
organophosphate catabolic process GO:0046434 148 0.011
synaptic transmission GO:0007268 235 0.011
reproductive process GO:0022414 372 0.011
hair cycle GO:0042633 3 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
Rat
protein complex subunit organization GO:0071822 302 0.011
Human
positive regulation of secretion by cell GO:1903532 128 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
cell adhesion GO:0007155 110 0.011
sexual reproduction GO:0019953 148 0.011
positive regulation of cell development GO:0010720 176 0.011
regulation of neuron projection development GO:0010975 161 0.011
response to purine containing compound GO:0014074 126 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
transmembrane transport GO:0055085 412 0.011
Human
response to biotic stimulus GO:0009607 226 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
Human
epithelium development GO:0060429 96 0.011
biological adhesion GO:0022610 110 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
regulation of nucleotide catabolic process GO:0030811 65 0.011
regulation of neuron differentiation GO:0045664 208 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
cell cycle process GO:0022402 57 0.011
regulation of peptide secretion GO:0002791 82 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
negative regulation of signaling GO:0023057 157 0.011
camera type eye development GO:0043010 48 0.011
organelle localization GO:0051640 55 0.010
defense response to other organism GO:0098542 17 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
regulation of cell migration GO:0030334 128 0.010
anion transmembrane transport GO:0098656 77 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
regulation of nucleic acid templated transcription GO:1903506 380 0.010
response to hyperoxia GO:0055093 45 0.010
fertilization GO:0009566 3 0.010
circulatory system process GO:0003013 183 0.010
regulation of catabolic process GO:0009894 113 0.010
Human
single fertilization GO:0007338 3 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.010
Human Rat
cellular macromolecule localization GO:0070727 122 0.010
regulation of peptide transport GO:0090087 87 0.010
nucleoside catabolic process GO:0009164 126 0.010
regulation of protein metabolic process GO:0051246 289 0.010
Human Rat
organ regeneration GO:0031100 101 0.010
Rat

Bax disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.054
nervous system disease DOID:863 0 0.054
central nervous system disease DOID:331 0 0.013