Rattus norvegicus

16 known processes

Mefv

Mediterranean fever

(Aliases: pyrin)

Mefv biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of neutrophil migration GO:1902622 6 0.221
cellular response to cytokine stimulus GO:0071345 127 0.162
regulation of cellular extravasation GO:0002691 2 0.161
carboxylic acid metabolic process GO:0019752 289 0.127
response to cytokine GO:0034097 215 0.116
catabolic process GO:0009056 351 0.104
defense response GO:0006952 194 0.100
Human
regulation of phosphorus metabolic process GO:0051174 349 0.098
positive regulation of neutrophil migration GO:1902624 6 0.093
response to molecule of bacterial origin GO:0002237 194 0.087
regulation of neutrophil chemotaxis GO:0090022 5 0.085
immune system process GO:0002376 204 0.074
positive regulation of phosphorus metabolic process GO:0010562 262 0.073
response to radiation GO:0009314 137 0.070
positive regulation of intracellular signal transduction GO:1902533 138 0.064
secretion GO:0046903 307 0.064
cation transport GO:0006812 382 0.061
positive regulation of neutrophil chemotaxis GO:0090023 5 0.060
carbohydrate derivative metabolic process GO:1901135 346 0.058
chemical homeostasis GO:0048878 292 0.058
protein complex biogenesis GO:0070271 263 0.058
cellular calcium ion homeostasis GO:0006874 160 0.058
divalent inorganic cation homeostasis GO:0072507 165 0.052
negative regulation of chronic inflammatory response GO:0002677 2 0.051
metanephric tubule morphogenesis GO:0072173 2 0.050
regulation of phosphate metabolic process GO:0019220 349 0.050
cellular component biogenesis GO:0044085 368 0.049
amine metabolic process GO:0009308 38 0.049
cell motility GO:0048870 202 0.048
appendage morphogenesis GO:0035107 4 0.048
secretion by cell GO:0032940 248 0.047
ion homeostasis GO:0050801 212 0.046
response to oxygen levels GO:0070482 265 0.046
protein oligomerization GO:0051259 191 0.045
angioblast cell migration GO:0035476 1 0.045
cellular ion homeostasis GO:0006873 184 0.045
g protein coupled receptor signaling pathway GO:0007186 242 0.045
macromolecular complex assembly GO:0065003 273 0.045
regulation of cellular localization GO:0060341 263 0.044
intracellular signal transduction GO:0035556 314 0.044
oxoacid metabolic process GO:0043436 290 0.043
protein complex assembly GO:0006461 263 0.042
lymphocyte chemotaxis GO:0048247 3 0.042
organic acid transport GO:0015849 116 0.041
ribonucleotide metabolic process GO:0009259 231 0.041
regulation of secretion GO:0051046 224 0.041
cellular amino acid metabolic process GO:0006520 107 0.040
regulation of locomotion GO:0040012 148 0.039
cellular cation homeostasis GO:0030003 180 0.039
protein homooligomerization GO:0051260 91 0.038
regulation of multicellular organismal development GO:2000026 376 0.037
nucleobase containing small molecule metabolic process GO:0055086 316 0.037
nucleoside phosphate metabolic process GO:0006753 283 0.037
cellular homeostasis GO:0019725 252 0.037
cellular lipid metabolic process GO:0044255 208 0.036
cytokine mediated signaling pathway GO:0019221 43 0.036
lipid metabolic process GO:0006629 283 0.036
positive regulation of secretion GO:0051047 140 0.036
cell migration GO:0016477 197 0.036
positive regulation of phosphorylation GO:0042327 177 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.035
cellular response to biotic stimulus GO:0071216 59 0.035
protein phosphorylation GO:0006468 345 0.034
neuron differentiation GO:0030182 368 0.034
regulation of immune system process GO:0002682 123 0.034
calcium ion homeostasis GO:0055074 162 0.034
purine nucleotide metabolic process GO:0006163 229 0.033
response to acid chemical GO:0001101 222 0.032
embryonic limb morphogenesis GO:0030326 4 0.032
inflammatory response to antigenic stimulus GO:0002437 18 0.031
organophosphate biosynthetic process GO:0090407 143 0.031
programmed cell death GO:0012501 392 0.031
homeostatic process GO:0042592 331 0.031
small molecule biosynthetic process GO:0044283 124 0.031
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.031
chronic inflammatory response to non antigenic stimulus GO:0002545 1 0.031
regulation of defense response GO:0031347 68 0.031
Human
single organism catabolic process GO:0044712 283 0.031
response to lipopolysaccharide GO:0032496 191 0.030
response to bacterium GO:0009617 200 0.030
cellular amine metabolic process GO:0044106 38 0.030
negative regulation of transport GO:0051051 136 0.030
neuron development GO:0048666 286 0.030
aging GO:0007568 241 0.029
regulation of chronic inflammatory response GO:0002676 3 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
neutrophil chemotaxis GO:0030593 11 0.029
cellular response to endogenous stimulus GO:0071495 377 0.029
locomotion GO:0040011 237 0.028
calcium ion transport GO:0006816 131 0.028
cellular component assembly GO:0022607 360 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
cellular metal ion homeostasis GO:0006875 172 0.027
positive regulation of signal transduction GO:0009967 175 0.027
regulation of secretion by cell GO:1903530 208 0.026
negative regulation of signaling GO:0023057 157 0.026
organic acid metabolic process GO:0006082 292 0.026
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.026
nucleotide metabolic process GO:0009117 279 0.026
signal transduction by phosphorylation GO:0023014 144 0.026
response to interleukin 15 GO:0070672 4 0.026
gastrulation GO:0007369 2 0.025
multicellular organismal signaling GO:0035637 44 0.025
cation transmembrane transport GO:0098655 263 0.025
cellular response to stress GO:0033554 269 0.024
cellular catabolic process GO:0044248 295 0.024
negative regulation of long term synaptic potentiation GO:1900272 1 0.024
ribose phosphate metabolic process GO:0019693 235 0.023
response to biotic stimulus GO:0009607 226 0.023
carbohydrate derivative catabolic process GO:1901136 147 0.023
embryonic appendage morphogenesis GO:0035113 4 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
t cell chemotaxis GO:0010818 2 0.022
cation homeostasis GO:0055080 195 0.022
limb morphogenesis GO:0035108 4 0.022
positive regulation of cell death GO:0010942 184 0.022
positive regulation of protein metabolic process GO:0051247 178 0.022
Human
cellular ketone metabolic process GO:0042180 51 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.021
regulation of chronic inflammatory response to non antigenic stimulus GO:0002880 1 0.021
response to inorganic substance GO:0010035 377 0.021
establishment of protein localization GO:0045184 141 0.021
cytosolic calcium ion homeostasis GO:0051480 140 0.021
anatomical structure morphogenesis GO:0009653 298 0.021
granulocyte migration GO:0097530 16 0.021
purine containing compound metabolic process GO:0072521 253 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
positive regulation of granulocyte chemotaxis GO:0071624 6 0.020
eosinophil chemotaxis GO:0048245 3 0.020
mapk cascade GO:0000165 140 0.020
organophosphate metabolic process GO:0019637 370 0.019
response to retinoic acid GO:0032526 63 0.019
metal ion homeostasis GO:0055065 186 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
reproductive process GO:0022414 372 0.019
single organism biosynthetic process GO:0044711 342 0.019
organic substance catabolic process GO:1901575 316 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
organophosphate catabolic process GO:0046434 148 0.019
circulatory system development GO:0072359 134 0.019
negative regulation of chronic inflammatory response to non antigenic stimulus GO:0002881 1 0.018
nitrogen compound transport GO:0071705 229 0.018
cytokine biosynthetic process GO:0042089 3 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
eosinophil migration GO:0072677 3 0.018
chemotaxis GO:0006935 66 0.018
positive regulation of developmental process GO:0051094 283 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
metanephric epithelium development GO:0072207 4 0.018
signal release GO:0023061 145 0.018
dephosphorylation GO:0016311 98 0.018
macromolecule localization GO:0033036 252 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
positive regulation of signaling GO:0023056 270 0.017
cellular carbohydrate metabolic process GO:0044262 72 0.017
response to hyperoxia GO:0055093 45 0.017
response to hypoxia GO:0001666 231 0.017
granulocyte chemotaxis GO:0071621 15 0.017
response to external biotic stimulus GO:0043207 221 0.017
second messenger mediated signaling GO:0019932 51 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
response to temperature stimulus GO:0009266 94 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
aromatic compound catabolic process GO:0019439 168 0.017
response to decreased oxygen levels GO:0036293 237 0.016
acid secretion GO:0046717 48 0.016
regulation of heterotypic cell cell adhesion GO:0034114 2 0.016
divalent inorganic cation transport GO:0072511 134 0.016
negative regulation of neutrophil apoptotic process GO:0033030 3 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
response to extracellular stimulus GO:0009991 380 0.016
negative regulation of amine transport GO:0051953 24 0.016
myeloid leukocyte activation GO:0002274 36 0.016
defense response to other organism GO:0098542 17 0.016
regulation of hydrolase activity GO:0051336 143 0.015
Human
regulation of catalytic activity GO:0050790 304 0.015
Human
regulation of b cell mediated immunity GO:0002712 2 0.015
regulation of mapk cascade GO:0043408 116 0.015
phospholipid biosynthetic process GO:0008654 29 0.015
regulation of ion transport GO:0043269 245 0.015
metanephric tubule development GO:0072170 4 0.015
negative regulation of secretion GO:0051048 82 0.015
brain development GO:0007420 247 0.015
regulation of hormone levels GO:0010817 187 0.015
response to tumor necrosis factor GO:0034612 56 0.015
positive regulation of nervous system development GO:0051962 178 0.015
positive regulation of protein modification process GO:0031401 142 0.015
multi multicellular organism process GO:0044706 138 0.015
cellular chemical homeostasis GO:0055082 247 0.015
regulation of immunoglobulin secretion GO:0051023 1 0.015
central nervous system development GO:0007417 311 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.014
biological adhesion GO:0022610 110 0.014
regulation of phosphorylation GO:0042325 248 0.014
phototransduction visible light GO:0007603 2 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
neurological system process GO:0050877 219 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
reproduction GO:0000003 245 0.014
cell cell signaling GO:0007267 335 0.014
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.014
positive regulation of cell communication GO:0010647 271 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
immune response GO:0006955 104 0.014
organic hydroxy compound biosynthetic process GO:1901617 51 0.014
gamete generation GO:0007276 124 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
monocarboxylic acid transport GO:0015718 52 0.014
positive regulation of mapk cascade GO:0043410 92 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
regulation of neuron differentiation GO:0045664 208 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
neutrophil migration GO:1990266 12 0.013
regulation of apoptotic process GO:0042981 335 0.013
transmission of nerve impulse GO:0019226 42 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
positive regulation of response to external stimulus GO:0032103 51 0.013
positive regulation of molecular function GO:0044093 230 0.013
Human
regulation of nervous system development GO:0051960 264 0.013
negative regulation of cell death GO:0060548 229 0.013
positive regulation of cell migration GO:0030335 96 0.013
multi organism reproductive process GO:0044703 262 0.013
axis specification GO:0009798 4 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
cell adhesion GO:0007155 110 0.012
regulation of metal ion transport GO:0010959 118 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
regulation of neutrophil apoptotic process GO:0033029 4 0.012
positive regulation of immune system process GO:0002684 90 0.012
carboxylic acid transport GO:0046942 115 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
regulation of signal transduction GO:0009966 318 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
positive regulation of angiogenesis GO:0045766 28 0.012
negative regulation of developmental process GO:0051093 125 0.012
muscle cell proliferation GO:0033002 84 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
organic anion transport GO:0015711 132 0.012
cellular response to molecule of bacterial origin GO:0071219 56 0.012
positive regulation of ion transport GO:0043270 94 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
Human
regulation of insulin secretion GO:0050796 65 0.012
renal system development GO:0072001 67 0.012
localization of cell GO:0051674 202 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
positive regulation of tumor necrosis factor superfamily cytokine production GO:1903557 8 0.011
regulation of cell differentiation GO:0045595 320 0.011
response to hexose GO:0009746 144 0.011
t cell migration GO:0072678 2 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
eye morphogenesis GO:0048592 4 0.011
innate immune response GO:0045087 35 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
heterocycle catabolic process GO:0046700 167 0.011
regulation of membrane potential GO:0042391 110 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
Human
cellular response to growth factor stimulus GO:0071363 162 0.011
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.011
regulation of molecular function GO:0065009 398 0.011
Human
alcohol metabolic process GO:0006066 77 0.011
cell projection organization GO:0030030 302 0.011
purine containing compound catabolic process GO:0072523 138 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
b cell activation involved in immune response GO:0002312 1 0.011
neuronal action potential GO:0019228 35 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
calcium ion transmembrane transport GO:0070588 70 0.011
nucleotide catabolic process GO:0009166 139 0.011
antibiotic transport GO:0042891 2 0.011
positive regulation of transport GO:0051050 245 0.011
peptide transport GO:0015833 97 0.011
anion transport GO:0006820 178 0.011
acute inflammatory response GO:0002526 58 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
regulation of cytokine biosynthetic process GO:0042035 3 0.010
lipid biosynthetic process GO:0008610 128 0.010
negative regulation of cellular metabolic process GO:0031324 281 0.010
regulation of cellular component organization GO:0051128 368 0.010
response to growth factor GO:0070848 189 0.010
transformation of host cell by virus GO:0019087 4 0.010
organic hydroxy compound metabolic process GO:1901615 115 0.010
response to metal ion GO:0010038 253 0.010
multicellular organismal reproductive process GO:0048609 233 0.010
positive regulation of cell development GO:0010720 176 0.010
regulation of catabolic process GO:0009894 113 0.010

Mefv disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
Human
nervous system disease DOID:863 0 0.028
musculoskeletal system disease DOID:17 0 0.028
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013