Rattus norvegicus

84 known processes

Araf

v-raf murine sarcoma 3611 viral oncogene homolog

(Aliases: Araf1)

Araf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to hypoxia GO:0001666 231 0.118
Rat
regulation of rna metabolic process GO:0051252 391 0.073
Fly
response to nutrient GO:0007584 248 0.071
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.069
regulation of cell differentiation GO:0045595 320 0.065
Fly
organophosphate biosynthetic process GO:0090407 143 0.064
programmed cell death GO:0012501 392 0.060
Human Fly
cellular response to oxygen containing compound GO:1901701 386 0.056
regulation of cell proliferation GO:0042127 359 0.056
Fly
reproduction GO:0000003 245 0.051
Worm Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.049
regulation of programmed cell death GO:0043067 341 0.048
Human Fly
calcium ion homeostasis GO:0055074 162 0.048
response to extracellular stimulus GO:0009991 380 0.047
Fly
cell cycle GO:0007049 101 0.046
Fly
reproductive process GO:0022414 372 0.046
Fly
ion homeostasis GO:0050801 212 0.046
nucleic acid templated transcription GO:0097659 379 0.044
Fly
positive regulation of signaling GO:0023056 270 0.044
homeostatic process GO:0042592 331 0.044
positive regulation of cell differentiation GO:0045597 217 0.044
Fly
cellular chemical homeostasis GO:0055082 247 0.044
organic acid metabolic process GO:0006082 292 0.043
response to carbohydrate GO:0009743 183 0.043
divalent inorganic cation homeostasis GO:0072507 165 0.043
chemical homeostasis GO:0048878 292 0.042
regulation of catalytic activity GO:0050790 304 0.042
cellular cation homeostasis GO:0030003 180 0.042
regulation of rna biosynthetic process GO:2001141 381 0.042
Fly
cellular lipid metabolic process GO:0044255 208 0.041
single organism reproductive process GO:0044702 297 0.041
Fly
response to monosaccharide GO:0034284 159 0.041
regulation of hormone secretion GO:0046883 106 0.041
positive regulation of transcription dna templated GO:0045893 197 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.039
cation homeostasis GO:0055080 195 0.039
positive regulation of hormone secretion GO:0046887 65 0.039
cellular calcium ion homeostasis GO:0006874 160 0.039
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.038
positive regulation of multicellular organismal process GO:0051240 387 0.037
Fly
synaptic transmission GO:0007268 235 0.037
response to decreased oxygen levels GO:0036293 237 0.037
Rat
regulation of signal transduction GO:0009966 318 0.036
regulation of phosphorylation GO:0042325 248 0.036
hormone transport GO:0009914 121 0.036
negative regulation of cellular metabolic process GO:0031324 281 0.036
Fly
divalent inorganic cation transport GO:0072511 134 0.035
positive regulation of gene expression GO:0010628 244 0.035
rna biosynthetic process GO:0032774 380 0.035
Fly
negative regulation of gene expression GO:0010629 199 0.035
cellular divalent inorganic cation homeostasis GO:0072503 162 0.035
response to wounding GO:0009611 254 0.034
transmembrane transport GO:0055085 412 0.034
positive regulation of cell communication GO:0010647 271 0.034
positive regulation of rna biosynthetic process GO:1902680 197 0.033
response to peptide GO:1901652 292 0.033
regulation of secretion GO:0051046 224 0.033
response to glucose GO:0009749 136 0.033
lipid metabolic process GO:0006629 283 0.033
cell projection organization GO:0030030 302 0.032
regulation of cellular protein metabolic process GO:0032268 267 0.032
positive regulation of cellular amine metabolic process GO:0033240 3 0.032
metal ion homeostasis GO:0055065 186 0.032
regulation of transcription dna templated GO:0006355 374 0.032
Fly
carboxylic acid catabolic process GO:0046395 49 0.031
positive regulation of nucleic acid templated transcription GO:1903508 197 0.031
response to nutrient levels GO:0031667 370 0.031
Fly
positive regulation of rna metabolic process GO:0051254 203 0.031
amine metabolic process GO:0009308 38 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
Fly
regulation of peptide transport GO:0090087 87 0.031
cellular ion homeostasis GO:0006873 184 0.030
regulation of cell cycle GO:0051726 73 0.030
Fly
gland development GO:0048732 155 0.029
Fly
secretion by cell GO:0032940 248 0.029
protein phosphorylation GO:0006468 345 0.029
positive regulation of cell development GO:0010720 176 0.029
Fly
regulation of hormone levels GO:0010817 187 0.028
regulation of cell development GO:0060284 263 0.028
Fly
oxoacid metabolic process GO:0043436 290 0.028
carboxylic acid metabolic process GO:0019752 289 0.028
organonitrogen compound biosynthetic process GO:1901566 167 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
negative regulation of biosynthetic process GO:0009890 168 0.028
circulatory system process GO:0003013 183 0.028
cellular response to nitrogen compound GO:1901699 210 0.028
positive regulation of protein metabolic process GO:0051247 178 0.027
rna metabolic process GO:0016070 406 0.027
Fly
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.026
multi organism reproductive process GO:0044703 262 0.026
Fly
response to estrogen GO:0043627 232 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
cyclic nucleotide metabolic process GO:0009187 80 0.026
carbohydrate homeostasis GO:0033500 75 0.026
regulation of secretion by cell GO:1903530 208 0.026
regulation of molecular function GO:0065009 398 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
macromolecular complex assembly GO:0065003 273 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
organophosphate metabolic process GO:0019637 370 0.025
cytosolic calcium ion homeostasis GO:0051480 140 0.025
locomotion GO:0040011 237 0.025
Fly
cellular amine metabolic process GO:0044106 38 0.025
response to oxygen levels GO:0070482 265 0.025
Rat
signal release GO:0023061 145 0.024
aging GO:0007568 241 0.024
Worm
positive regulation of biosynthetic process GO:0009891 319 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
cell cell signaling GO:0007267 335 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
Fly
transcription dna templated GO:0006351 377 0.024
Fly
lipid biosynthetic process GO:0008610 128 0.024
hormone secretion GO:0046879 115 0.023
neuron differentiation GO:0030182 368 0.023
Fly
camp metabolic process GO:0046058 63 0.023
regulation of neuron death GO:1901214 115 0.023
regulation of cellular component organization GO:0051128 368 0.023
response to peptide hormone GO:0043434 278 0.023
single organism biosynthetic process GO:0044711 342 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
Fly
ribose phosphate metabolic process GO:0019693 235 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
Fly
positive regulation of cell death GO:0010942 184 0.022
cellular response to peptide GO:1901653 133 0.022
organelle organization GO:0006996 266 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
positive regulation of developmental process GO:0051094 283 0.022
Fly
cyclic purine nucleotide metabolic process GO:0052652 62 0.022
cellular homeostasis GO:0019725 252 0.022
multicellular organism reproduction GO:0032504 233 0.022
Fly
regulation of synaptic transmission GO:0050804 141 0.022
multi multicellular organism process GO:0044706 138 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
organic substance catabolic process GO:1901575 316 0.021
Human
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
negative regulation of metabolic process GO:0009892 331 0.021
Fly
apoptotic process GO:0006915 381 0.021
Human Fly
glucose homeostasis GO:0042593 75 0.021
positive regulation of secretion by cell GO:1903532 128 0.021
monocarboxylic acid metabolic process GO:0032787 152 0.021
regulation of calcium ion transport GO:0051924 77 0.021
fatty acid catabolic process GO:0009062 26 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
negative regulation of cell communication GO:0010648 158 0.020
Fly
purine containing compound metabolic process GO:0072521 253 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
Fly
response to hexose GO:0009746 144 0.020
peptide hormone secretion GO:0030072 84 0.019
metal ion transport GO:0030001 289 0.019
neuron development GO:0048666 286 0.019
learning or memory GO:0007611 90 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
Human Fly
sexual reproduction GO:0019953 148 0.019
Fly
carbohydrate derivative biosynthetic process GO:1901137 124 0.019
positive regulation of secretion GO:0051047 140 0.019
cellular response to stress GO:0033554 269 0.019
Fly
positive regulation of signal transduction GO:0009967 175 0.019
regulation of apoptotic process GO:0042981 335 0.019
Human Fly
actin filament based process GO:0030029 86 0.019
calcium ion import GO:0070509 22 0.019
positive regulation of molecular function GO:0044093 230 0.019
cellular component assembly GO:0022607 360 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
regulation of homeostatic process GO:0032844 101 0.018
regulation of carbohydrate metabolic process GO:0006109 41 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
single organism organelle organization GO:1902589 180 0.018
response to mechanical stimulus GO:0009612 134 0.018
small molecule catabolic process GO:0044282 59 0.018
divalent metal ion transport GO:0070838 132 0.018
regulation of neurogenesis GO:0050767 247 0.018
Fly
regulation of protein modification process GO:0031399 194 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
intracellular signal transduction GO:0035556 314 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
neuron apoptotic process GO:0051402 88 0.018
protein transport GO:0015031 132 0.018
positive regulation of peptide secretion GO:0002793 52 0.018
epithelium development GO:0060429 96 0.017
Fly
regulation of protein metabolic process GO:0051246 289 0.017
organic anion transport GO:0015711 132 0.017
neuron projection development GO:0031175 273 0.017
response to axon injury GO:0048678 59 0.017
cellular component biogenesis GO:0044085 368 0.017
sequestering of calcium ion GO:0051208 8 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
ion transmembrane transport GO:0034220 365 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
nucleotide biosynthetic process GO:0009165 98 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
biological adhesion GO:0022610 110 0.017
nitrogen compound transport GO:0071705 229 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
peptide secretion GO:0002790 86 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
regulation of transmembrane transport GO:0034762 122 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
intracellular transport GO:0046907 185 0.016
oxidation reduction process GO:0055114 304 0.016
cellular ketone metabolic process GO:0042180 51 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
neurological system process GO:0050877 219 0.016
regulation of peptide hormone secretion GO:0090276 80 0.016
single organism catabolic process GO:0044712 283 0.016
Fly
regulation of neuron projection development GO:0010975 161 0.016
regulation of insulin secretion GO:0050796 65 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
Fly
regulation of peptide secretion GO:0002791 82 0.016
organic acid transport GO:0015849 116 0.016
regulation of immune response GO:0050776 55 0.016
cognition GO:0050890 92 0.016
positive regulation of transport GO:0051050 245 0.016
sex differentiation GO:0007548 113 0.016
response to growth factor GO:0070848 189 0.016
cyclic nucleotide biosynthetic process GO:0009190 63 0.016
regulation of camp metabolic process GO:0030814 43 0.016
response to acid chemical GO:0001101 222 0.016
regulation of cellular localization GO:0060341 263 0.016
cellular response to lipid GO:0071396 201 0.016
neuron death GO:0070997 127 0.016
negative regulation of cell death GO:0060548 229 0.016
Human Fly
secretion GO:0046903 307 0.016
camp biosynthetic process GO:0006171 47 0.015
development of primary sexual characteristics GO:0045137 107 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
Fly
axis specification GO:0009798 4 0.015
Fly
protein oligomerization GO:0051259 191 0.015
nucleotide metabolic process GO:0009117 279 0.015
lipid oxidation GO:0034440 30 0.015
peptide transport GO:0015833 97 0.015
blood circulation GO:0008015 183 0.015
positive regulation of peptide hormone secretion GO:0090277 50 0.015
alpha amino acid metabolic process GO:1901605 71 0.015
monocarboxylic acid catabolic process GO:0072329 28 0.015
negative regulation of signaling GO:0023057 157 0.015
Fly
cell type specific apoptotic process GO:0097285 134 0.015
carboxylic acid transport GO:0046942 115 0.015
regulation of cell projection organization GO:0031344 175 0.015
response to ethanol GO:0045471 162 0.014
response to glucocorticoid GO:0051384 223 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
insulin secretion GO:0030073 69 0.014
regulation of metal ion transport GO:0010959 118 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.014
regulation of tube size GO:0035150 89 0.014
cellular component movement GO:0006928 248 0.014
Fly
cell motility GO:0048870 202 0.014
Fly
response to radiation GO:0009314 137 0.014
regulation of system process GO:0044057 208 0.014
response to inorganic substance GO:0010035 377 0.014
cytoplasmic transport GO:0016482 115 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
regulation of nervous system development GO:0051960 264 0.014
Fly
negative regulation of programmed cell death GO:0043069 183 0.014
Human Fly
cellular response to acid chemical GO:0071229 75 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
acid secretion GO:0046717 48 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
organic acid catabolic process GO:0016054 49 0.013
regulation of neuron apoptotic process GO:0043523 83 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
negative regulation of secretion by cell GO:1903531 72 0.013
amide transport GO:0042886 105 0.013
immune system process GO:0002376 204 0.013
Fly
gamete generation GO:0007276 124 0.013
Fly
response to bacterium GO:0009617 200 0.013
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
sequestering of metal ion GO:0051238 9 0.013
female sex differentiation GO:0046660 59 0.013
regulation of response to external stimulus GO:0032101 106 0.013
Fly
regulation of neuron differentiation GO:0045664 208 0.013
Fly
negative regulation of molecular function GO:0044092 133 0.013
memory GO:0007613 54 0.013
sensory perception of pain GO:0019233 73 0.013
response to estradiol GO:0032355 164 0.013
female pregnancy GO:0007565 122 0.013
fatty acid oxidation GO:0019395 29 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
cell substrate adhesion GO:0031589 29 0.012
muscle system process GO:0003012 115 0.012
alcohol metabolic process GO:0006066 77 0.012
vascular process in circulatory system GO:0003018 96 0.012
regulation of blood vessel size GO:0050880 89 0.012
positive regulation of ion transport GO:0043270 94 0.012
lipid modification GO:0030258 52 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
catabolic process GO:0009056 351 0.012
Human Fly
positive regulation of insulin secretion GO:0032024 36 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
bmp signaling pathway GO:0030509 4 0.012
negative regulation of neuron death GO:1901215 69 0.012
cellular catabolic process GO:0044248 295 0.012
Human Fly
response to amino acid GO:0043200 75 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
response to corticosteroid GO:0031960 235 0.012
proteolysis GO:0006508 175 0.012
Human
cell migration GO:0016477 197 0.012
Fly
response to retinoic acid GO:0032526 63 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
cellular response to glucose stimulus GO:0071333 65 0.012
response to electrical stimulus GO:0051602 56 0.012
regulation of camp biosynthetic process GO:0030817 38 0.012
developmental process involved in reproduction GO:0003006 159 0.012
Fly
purine ribonucleotide biosynthetic process GO:0009152 81 0.012
spermatogenesis GO:0007283 99 0.012
Fly
positive regulation of phosphorylation GO:0042327 177 0.011
second messenger mediated signaling GO:0019932 51 0.011
fatty acid metabolic process GO:0006631 99 0.011
heterocycle catabolic process GO:0046700 167 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
single organism intracellular transport GO:1902582 166 0.011
male gamete generation GO:0048232 99 0.011
Fly
purine nucleotide catabolic process GO:0006195 136 0.011
response to metal ion GO:0010038 253 0.011
regulation of ion transport GO:0043269 245 0.011
chromosome segregation GO:0007059 2 0.011
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.011
cellular response to external stimulus GO:0071496 118 0.011
Fly
purine containing compound biosynthetic process GO:0072522 85 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
cation transmembrane transport GO:0098655 263 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
ossification GO:0001503 70 0.011
cell cycle process GO:0022402 57 0.011
tissue development GO:0009888 252 0.011
Fly
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.011
epithelial cell differentiation GO:0030855 71 0.011
Fly
positive regulation of lipid kinase activity GO:0090218 2 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
Fly
regulation of anatomical structure size GO:0090066 135 0.011
male mating behavior GO:0060179 3 0.011
gonad development GO:0008406 104 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
anion transport GO:0006820 178 0.010
cellular response to hexose stimulus GO:0071331 65 0.010
positive regulation of catalytic activity GO:0043085 184 0.010
reproductive system development GO:0061458 128 0.010
ras protein signal transduction GO:0007265 29 0.010
Worm Fly
lipid storage GO:0019915 1 0.010
regulation of protein kinase activity GO:0045859 105 0.010
regulation of ion transmembrane transport GO:0034765 121 0.010
regulation of synaptic plasticity GO:0048167 70 0.010
glial cell differentiation GO:0010001 65 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
response to lipopolysaccharide GO:0032496 191 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
regulation of blood circulation GO:1903522 110 0.010
localization of cell GO:0051674 202 0.010
Fly
lipid catabolic process GO:0016042 46 0.010

Araf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.014
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
musculoskeletal system disease DOID:17 0 0.011
inherited metabolic disorder DOID:655 0 0.010