Rattus norvegicus

63 known processes

Gjb6

gap junction protein, beta 6

(Aliases: Cx30)

Gjb6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nitrogen compound transport GO:0071705 229 0.182
Rat
cellular component assembly GO:0022607 360 0.152
Rat
organic acid metabolic process GO:0006082 292 0.113
oxoacid metabolic process GO:0043436 290 0.107
carboxylic acid metabolic process GO:0019752 289 0.104
blood circulation GO:0008015 183 0.102
Rat
macromolecular complex assembly GO:0065003 273 0.089
Rat
cell cell signaling GO:0007267 335 0.083
Rat
central nervous system development GO:0007417 311 0.082
brain development GO:0007420 247 0.081
regulation of hormone levels GO:0010817 187 0.080
Rat
protein complex subunit organization GO:0071822 302 0.075
Rat
cellular response to endogenous stimulus GO:0071495 377 0.074
protein complex biogenesis GO:0070271 263 0.074
Rat
tissue development GO:0009888 252 0.072
Rat
response to acid chemical GO:0001101 222 0.070
positive regulation of cell proliferation GO:0008284 249 0.067
response to ethanol GO:0045471 162 0.062
head development GO:0060322 247 0.060
single organism biosynthetic process GO:0044711 342 0.059
hormone transport GO:0009914 121 0.058
Rat
cellular component biogenesis GO:0044085 368 0.055
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.054
positive regulation of cell communication GO:0010647 271 0.053
Rat
rna metabolic process GO:0016070 406 0.052
lipid metabolic process GO:0006629 283 0.051
regulation of multicellular organismal development GO:2000026 376 0.049
Rat
cellular lipid metabolic process GO:0044255 208 0.049
monocarboxylic acid metabolic process GO:0032787 152 0.048
neuron differentiation GO:0030182 368 0.047
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.046
Rat
regulation of secretion by cell GO:1903530 208 0.045
Rat
neurological system process GO:0050877 219 0.044
Rat
macromolecular complex subunit organization GO:0043933 339 0.043
Rat
locomotion GO:0040011 237 0.043
regulation of programmed cell death GO:0043067 341 0.042
small molecule biosynthetic process GO:0044283 124 0.042
neuron development GO:0048666 286 0.042
Rat
response to corticosteroid GO:0031960 235 0.041
cellular response to oxygen containing compound GO:1901701 386 0.040
response to estrogen GO:0043627 232 0.040
Rat
homeostatic process GO:0042592 331 0.040
cellular response to organonitrogen compound GO:0071417 197 0.040
organic acid biosynthetic process GO:0016053 83 0.040
cellular response to hormone stimulus GO:0032870 247 0.040
oxidation reduction process GO:0055114 304 0.039
response to estradiol GO:0032355 164 0.038
Rat
positive regulation of protein phosphorylation GO:0001934 135 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
response to ketone GO:1901654 182 0.036
Rat
positive regulation of gene expression GO:0010628 244 0.036
regulation of phosphorus metabolic process GO:0051174 349 0.036
regulation of anatomical structure morphogenesis GO:0022603 141 0.036
cell morphogenesis GO:0000902 142 0.035
Rat
fatty acid metabolic process GO:0006631 99 0.035
apoptotic process GO:0006915 381 0.034
circulatory system process GO:0003013 183 0.034
Rat
cellular amino acid metabolic process GO:0006520 107 0.034
reproductive process GO:0022414 372 0.034
Rat
cell projection organization GO:0030030 302 0.034
Rat
positive regulation of signaling GO:0023056 270 0.034
Rat
gland development GO:0048732 155 0.033
localization of cell GO:0051674 202 0.033
response to glucocorticoid GO:0051384 223 0.033
anatomical structure morphogenesis GO:0009653 298 0.033
Rat
protein phosphorylation GO:0006468 345 0.033
secretion GO:0046903 307 0.032
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.032
regulation of molecular function GO:0065009 398 0.032
single organism organelle organization GO:1902589 180 0.032
cellular component morphogenesis GO:0032989 155 0.032
Rat
amine metabolic process GO:0009308 38 0.032
monocarboxylic acid transport GO:0015718 52 0.032
cell adhesion GO:0007155 110 0.032
cellular component movement GO:0006928 248 0.031
response to carbohydrate GO:0009743 183 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.031
protein complex assembly GO:0006461 263 0.031
Rat
reproduction GO:0000003 245 0.031
Rat
organelle organization GO:0006996 266 0.030
positive regulation of protein metabolic process GO:0051247 178 0.030
Rat
regulation of protein modification process GO:0031399 194 0.030
intracellular signal transduction GO:0035556 314 0.030
single organism reproductive process GO:0044702 297 0.030
Rat
response to metal ion GO:0010038 253 0.030
cellular amine metabolic process GO:0044106 38 0.030
response to inorganic substance GO:0010035 377 0.030
Rat
cellular ketone metabolic process GO:0042180 51 0.030
organic hydroxy compound metabolic process GO:1901615 115 0.030
positive regulation of transport GO:0051050 245 0.029
Rat
cardiovascular system development GO:0072358 134 0.029
Rat
lipid biosynthetic process GO:0008610 128 0.029
positive regulation of protein modification process GO:0031401 142 0.029
regulation of cellular localization GO:0060341 263 0.029
Rat
regulation of cellular component organization GO:0051128 368 0.029
Rat
positive regulation of cell death GO:0010942 184 0.028
negative regulation of cell death GO:0060548 229 0.028
regulation of cell development GO:0060284 263 0.028
regulation of cell proliferation GO:0042127 359 0.028
response to extracellular stimulus GO:0009991 380 0.028
positive regulation of molecular function GO:0044093 230 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
organic anion transport GO:0015711 132 0.027
Rat
carboxylic acid biosynthetic process GO:0046394 83 0.027
hormone secretion GO:0046879 115 0.027
Rat
multicellular organismal reproductive process GO:0048609 233 0.027
Rat
catabolic process GO:0009056 351 0.027
Rat
axon development GO:0061564 96 0.027
neurotransmitter transport GO:0006836 42 0.027
positive regulation of cellular protein metabolic process GO:0032270 167 0.027
heart morphogenesis GO:0003007 3 0.027
regulation of neurogenesis GO:0050767 247 0.027
negative regulation of secretion by cell GO:1903531 72 0.027
regulation of apoptotic process GO:0042981 335 0.027
action potential GO:0001508 54 0.026
sodium ion transport GO:0006814 82 0.026
cell motility GO:0048870 202 0.026
response to nutrient levels GO:0031667 370 0.026
transcription dna templated GO:0006351 377 0.026
amino acid transport GO:0006865 70 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
signal release GO:0023061 145 0.026
Rat
behavior GO:0007610 205 0.025
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
Rat
cell projection morphogenesis GO:0048858 123 0.025
Rat
regulation of protein metabolic process GO:0051246 289 0.025
Rat
amide transport GO:0042886 105 0.025
Rat
response to toxic substance GO:0009636 133 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
Rat
programmed cell death GO:0012501 392 0.024
single organism catabolic process GO:0044712 283 0.024
cellular response to peptide GO:1901653 133 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
vascular process in circulatory system GO:0003018 96 0.024
Rat
response to peptide GO:1901652 292 0.024
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.023
cellular chemical homeostasis GO:0055082 247 0.023
negative regulation of response to stimulus GO:0048585 155 0.023
Rat
regulation of phosphate metabolic process GO:0019220 349 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
regulation of cellular component movement GO:0051270 150 0.023
regulation of blood circulation GO:1903522 110 0.023
Rat
cellular response to nitrogen compound GO:1901699 210 0.023
response to biotic stimulus GO:0009607 226 0.022
alcohol metabolic process GO:0006066 77 0.022
muscle cell proliferation GO:0033002 84 0.022
Rat
response to oxygen levels GO:0070482 265 0.022
multi organism reproductive process GO:0044703 262 0.022
Rat
regulation of phosphorylation GO:0042325 248 0.022
positive regulation of signal transduction GO:0009967 175 0.022
organic acid transport GO:0015849 116 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
response to transition metal nanoparticle GO:1990267 122 0.022
regulation of catalytic activity GO:0050790 304 0.022
regulation of cell differentiation GO:0045595 320 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
neuron projection development GO:0031175 273 0.021
Rat
negative regulation of metabolic process GO:0009892 331 0.021
Rat
multi multicellular organism process GO:0044706 138 0.021
Rat
female pregnancy GO:0007565 122 0.021
Rat
cellular response to lipid GO:0071396 201 0.021
learning or memory GO:0007611 90 0.021
organonitrogen compound catabolic process GO:1901565 179 0.021
regulation of kinase activity GO:0043549 117 0.021
response to wounding GO:0009611 254 0.021
Rat
regulation of neurotransmitter levels GO:0001505 42 0.021
protein homooligomerization GO:0051260 91 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
rna biosynthetic process GO:0032774 380 0.020
response to amino acid GO:0043200 75 0.020
organic substance catabolic process GO:1901575 316 0.020
Rat
secretion by cell GO:0032940 248 0.020
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.020
Rat
epithelium development GO:0060429 96 0.020
Rat
regulation of signal transduction GO:0009966 318 0.020
response to insulin GO:0032868 133 0.020
developmental process involved in reproduction GO:0003006 159 0.020
Rat
regulation of locomotion GO:0040012 148 0.020
regulation of rna metabolic process GO:0051252 391 0.019
cellular response to peptide hormone stimulus GO:0071375 120 0.019
regulation of anatomical structure size GO:0090066 135 0.019
Rat
cellular response to organic cyclic compound GO:0071407 202 0.019
chemical homeostasis GO:0048878 292 0.019
gliogenesis GO:0042063 93 0.019
ion homeostasis GO:0050801 212 0.019
Rat
regulation of system process GO:0044057 208 0.019
Rat
response to fatty acid GO:0070542 65 0.019
neuron projection morphogenesis GO:0048812 122 0.019
Rat
positive regulation of neurogenesis GO:0050769 165 0.019
anion transport GO:0006820 178 0.019
Rat
regulation of tube size GO:0035150 89 0.019
Rat
regulation of nervous system development GO:0051960 264 0.019
positive regulation of apoptotic process GO:0043065 154 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
positive regulation of secretion by cell GO:1903532 128 0.018
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.018
response to external biotic stimulus GO:0043207 221 0.018
cellular response to acid chemical GO:0071229 75 0.018
response to hypoxia GO:0001666 231 0.018
positive regulation of nervous system development GO:0051962 178 0.017
protein oligomerization GO:0051259 191 0.017
Rat
regulation of secretion GO:0051046 224 0.017
Rat
regulation of mapk cascade GO:0043408 116 0.017
organic hydroxy compound transport GO:0015850 77 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
smooth muscle cell proliferation GO:0048659 77 0.017
regulation of smooth muscle cell proliferation GO:0048660 75 0.017
response to peptide hormone GO:0043434 278 0.017
Rat
cell migration GO:0016477 197 0.017
regulation of membrane potential GO:0042391 110 0.017
synaptic transmission GO:0007268 235 0.017
tube development GO:0035295 89 0.017
response to glucose GO:0009749 136 0.017
regulation of nucleic acid templated transcription GO:1903506 380 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.016
cellular catabolic process GO:0044248 295 0.016
small molecule catabolic process GO:0044282 59 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
growth GO:0040007 165 0.016
Rat
wound healing GO:0042060 122 0.016
Rat
neuronal action potential GO:0019228 35 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
glycosyl compound catabolic process GO:1901658 126 0.016
regulation of cell motility GO:2000145 131 0.016
regulation of transferase activity GO:0051338 123 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.016
single organism behavior GO:0044708 130 0.016
Rat
proteolysis GO:0006508 175 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
response to growth factor GO:0070848 189 0.016
carbohydrate metabolic process GO:0005975 130 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
negative regulation of signaling GO:0023057 157 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
aging GO:0007568 241 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
anatomical structure formation involved in morphogenesis GO:0048646 83 0.015
nucleic acid templated transcription GO:0097659 379 0.015
urogenital system development GO:0001655 78 0.015
peptide hormone secretion GO:0030072 84 0.015
Rat
carboxylic acid transport GO:0046942 115 0.015
response to radiation GO:0009314 137 0.015
negative regulation of gene expression GO:0010629 199 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
response to alkaloid GO:0043279 132 0.014
response to lipopolysaccharide GO:0032496 191 0.014
multicellular organismal signaling GO:0035637 44 0.014
positive regulation of developmental process GO:0051094 283 0.014
axon ensheathment GO:0008366 40 0.014
ion transmembrane transport GO:0034220 365 0.014
acid secretion GO:0046717 48 0.014
regeneration GO:0031099 163 0.014
regulation of cell projection size GO:0032536 1 0.014
ras protein signal transduction GO:0007265 29 0.014
organ regeneration GO:0031100 101 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
muscle structure development GO:0061061 87 0.014
Rat
response to monosaccharide GO:0034284 159 0.014
peptidyl tyrosine phosphorylation GO:0018108 72 0.014
amine transport GO:0015837 57 0.013
response to purine containing compound GO:0014074 126 0.013
reproductive structure development GO:0048608 128 0.013
Rat
biological adhesion GO:0022610 110 0.013
response to fungicide GO:0060992 20 0.013
negative regulation of developmental process GO:0051093 125 0.013
Rat
regulation of peptide hormone secretion GO:0090276 80 0.013
Rat
purine nucleoside metabolic process GO:0042278 169 0.013
chemotaxis GO:0006935 66 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
Rat
negative regulation of transport GO:0051051 136 0.013
defense response GO:0006952 194 0.013
Rat
positive regulation of kinase activity GO:0033674 77 0.013
limb morphogenesis GO:0035108 4 0.013
response to vitamin GO:0033273 131 0.013
vasoconstriction GO:0042310 54 0.013
Rat
regulation of transcription dna templated GO:0006355 374 0.013
neuron death GO:0070997 127 0.013
endomembrane system organization GO:0010256 48 0.013
cellular homeostasis GO:0019725 252 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.012
negative regulation of cell communication GO:0010648 158 0.012
membrane organization GO:0061024 94 0.012
cellular lipid catabolic process GO:0044242 37 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
terpenoid metabolic process GO:0006721 37 0.012
regulation of response to stress GO:0080134 126 0.012
Rat
cellular calcium ion homeostasis GO:0006874 160 0.012
Rat
response to nutrient GO:0007584 248 0.012
peptidyl tyrosine modification GO:0018212 72 0.012
response to mechanical stimulus GO:0009612 134 0.012
Rat
nucleoside metabolic process GO:0009116 179 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
regulation of neuron death GO:1901214 115 0.012
axonogenesis GO:0007409 71 0.012
transmembrane transport GO:0055085 412 0.012
Rat
response to cytokine GO:0034097 215 0.012
calcium ion homeostasis GO:0055074 162 0.012
Rat
response to hyperoxia GO:0055093 45 0.012
organophosphate metabolic process GO:0019637 370 0.012
cellular macromolecular complex assembly GO:0034622 58 0.012
chromosome segregation GO:0007059 2 0.012
positive regulation of transferase activity GO:0051347 81 0.012
response to decreased oxygen levels GO:0036293 237 0.012
regulation of synaptic transmission GO:0050804 141 0.012
organophosphate catabolic process GO:0046434 148 0.012
hormone metabolic process GO:0042445 69 0.011
response to other organism GO:0051707 220 0.011
taxis GO:0042330 67 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
myelination GO:0042552 39 0.011
reproductive system development GO:0061458 128 0.011
Rat
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
Rat
negative regulation of nervous system development GO:0051961 79 0.011
positive regulation of secretion GO:0051047 140 0.011
Rat
synaptic growth at neuromuscular junction GO:0051124 1 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
regulation of cell projection organization GO:0031344 175 0.011
cell part morphogenesis GO:0032990 123 0.011
Rat
response to activity GO:0014823 73 0.011
regulation of neuron differentiation GO:0045664 208 0.011
response to dexamethasone GO:0071548 49 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
steroid metabolic process GO:0008202 73 0.011
peptidyl amino acid modification GO:0018193 126 0.011
cellular response to alcohol GO:0097306 87 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
glial cell differentiation GO:0010001 65 0.011
axis specification GO:0009798 4 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
response to retinoic acid GO:0032526 63 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
Rat
anterior posterior pattern specification GO:0009952 1 0.010
regulation of body fluid levels GO:0050878 90 0.010
Rat
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
heart contraction GO:0060047 57 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
negative regulation of signal transduction GO:0009968 83 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
isoprenoid metabolic process GO:0006720 45 0.010
cation homeostasis GO:0055080 195 0.010
Rat
response to molecule of bacterial origin GO:0002237 194 0.010
mesoderm development GO:0007498 2 0.010
cell cycle checkpoint GO:0000075 2 0.010
liver development GO:0001889 90 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
monocarboxylic acid biosynthetic process GO:0072330 48 0.010
regulation of neuron projection development GO:0010975 161 0.010
embryonic limb morphogenesis GO:0030326 4 0.010

Gjb6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
Human
nervous system disease DOID:863 0 0.027
Human
sensory system disease DOID:0050155 0 0.015
Human
disease of metabolism DOID:0014667 0 0.015
inherited metabolic disorder DOID:655 0 0.014