Rattus norvegicus

74 known processes

Tox3

TOX high mobility group box family member 3

(Aliases: Tnrc9)

Tox3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 377 0.129
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.108
regulation of neuron differentiation GO:0045664 208 0.094
regulation of multicellular organismal development GO:2000026 376 0.090
regulation of rna metabolic process GO:0051252 391 0.088
transcription from rna polymerase ii promoter GO:0006366 252 0.082
Rat
anatomical structure morphogenesis GO:0009653 298 0.081
regulation of cellular localization GO:0060341 263 0.077
regulation of nucleic acid templated transcription GO:1903506 380 0.076
regulation of nervous system development GO:0051960 264 0.074
regulation of cell development GO:0060284 263 0.071
intracellular signal transduction GO:0035556 314 0.070
neuron differentiation GO:0030182 368 0.070
regulation of cell differentiation GO:0045595 320 0.070
response to extracellular stimulus GO:0009991 380 0.069
nucleic acid templated transcription GO:0097659 379 0.068
regulation of transcription dna templated GO:0006355 374 0.065
rna biosynthetic process GO:0032774 380 0.064
regulation of programmed cell death GO:0043067 341 0.062
Human
homeostatic process GO:0042592 331 0.059
regulation of rna biosynthetic process GO:2001141 381 0.059
cellular response to oxygen containing compound GO:1901701 386 0.058
neuron projection development GO:0031175 273 0.056
cellular component movement GO:0006928 248 0.055
programmed cell death GO:0012501 392 0.053
Human
rna metabolic process GO:0016070 406 0.053
regulation of phosphorus metabolic process GO:0051174 349 0.053
regulation of signal transduction GO:0009966 318 0.052
cellular response to endogenous stimulus GO:0071495 377 0.051
cation transport GO:0006812 382 0.051
regulation of neurogenesis GO:0050767 247 0.051
regulation of phosphate metabolic process GO:0019220 349 0.049
positive regulation of multicellular organismal process GO:0051240 387 0.049
response to nutrient levels GO:0031667 370 0.049
response to inorganic substance GO:0010035 377 0.048
neuron development GO:0048666 286 0.048
regulation of intracellular signal transduction GO:1902531 218 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.046
Rat
regulation of secretion by cell GO:1903530 208 0.045
regulation of anatomical structure morphogenesis GO:0022603 141 0.044
regulation of cellular component organization GO:0051128 368 0.044
cellular component morphogenesis GO:0032989 155 0.044
positive regulation of cell differentiation GO:0045597 217 0.043
positive regulation of transport GO:0051050 245 0.043
cellular response to stress GO:0033554 269 0.043
cell morphogenesis involved in differentiation GO:0000904 119 0.042
negative regulation of multicellular organismal process GO:0051241 203 0.042
cell projection organization GO:0030030 302 0.042
negative regulation of biosynthetic process GO:0009890 168 0.041
negative regulation of metabolic process GO:0009892 331 0.040
central nervous system development GO:0007417 311 0.040
negative regulation of cellular metabolic process GO:0031324 281 0.040
positive regulation of biosynthetic process GO:0009891 319 0.040
head development GO:0060322 247 0.039
chemical homeostasis GO:0048878 292 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.038
response to metal ion GO:0010038 253 0.038
locomotion GO:0040011 237 0.037
secretion GO:0046903 307 0.037
protein complex assembly GO:0006461 263 0.037
regulation of catalytic activity GO:0050790 304 0.037
regulation of system process GO:0044057 208 0.037
negative regulation of response to stimulus GO:0048585 155 0.036
organophosphate metabolic process GO:0019637 370 0.036
apoptotic process GO:0006915 381 0.036
Human
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.036
macromolecule localization GO:0033036 252 0.036
organic acid metabolic process GO:0006082 292 0.036
cellular component biogenesis GO:0044085 368 0.035
protein complex biogenesis GO:0070271 263 0.035
ion homeostasis GO:0050801 212 0.035
response to nutrient GO:0007584 248 0.035
regulation of cell proliferation GO:0042127 359 0.035
cell morphogenesis GO:0000902 142 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.035
positive regulation of response to stimulus GO:0048584 285 0.034
protein localization GO:0008104 191 0.034
positive regulation of gene expression GO:0010628 244 0.034
regulation of neuron projection development GO:0010975 161 0.034
regulation of secretion GO:0051046 224 0.033
brain development GO:0007420 247 0.033
regulation of molecular function GO:0065009 398 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
positive regulation of rna biosynthetic process GO:1902680 197 0.033
single organism intracellular transport GO:1902582 166 0.033
cell cell signaling GO:0007267 335 0.033
negative regulation of signaling GO:0023057 157 0.033
regulation of cellular component movement GO:0051270 150 0.032
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.032
cellular amino acid metabolic process GO:0006520 107 0.032
multicellular organism reproduction GO:0032504 233 0.032
cellular homeostasis GO:0019725 252 0.032
positive regulation of transcription dna templated GO:0045893 197 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.031
growth GO:0040007 165 0.031
cellular amine metabolic process GO:0044106 38 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
cellular ion homeostasis GO:0006873 184 0.031
response to cytokine GO:0034097 215 0.030
multicellular organismal reproductive process GO:0048609 233 0.030
cellular component assembly GO:0022607 360 0.030
single organism reproductive process GO:0044702 297 0.030
Rat
secretion by cell GO:0032940 248 0.030
negative regulation of transport GO:0051051 136 0.030
g protein coupled receptor signaling pathway GO:0007186 242 0.030
metal ion homeostasis GO:0055065 186 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
cellular cation homeostasis GO:0030003 180 0.030
intracellular transport GO:0046907 185 0.030
ion transmembrane transport GO:0034220 365 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
positive regulation of cell development GO:0010720 176 0.029
reproductive process GO:0022414 372 0.029
Rat
negative regulation of gene expression GO:0010629 199 0.029
reproduction GO:0000003 245 0.029
purine containing compound metabolic process GO:0072521 253 0.028
regulation of ion transport GO:0043269 245 0.028
reproductive structure development GO:0048608 128 0.028
Rat
protein complex subunit organization GO:0071822 302 0.028
nitrogen compound transport GO:0071705 229 0.028
cellular chemical homeostasis GO:0055082 247 0.027
circulatory system development GO:0072359 134 0.027
positive regulation of molecular function GO:0044093 230 0.027
regulation of apoptotic process GO:0042981 335 0.027
Human
calcium ion homeostasis GO:0055074 162 0.027
negative regulation of rna metabolic process GO:0051253 123 0.027
axon development GO:0061564 96 0.027
neuron projection morphogenesis GO:0048812 122 0.027
response to growth factor GO:0070848 189 0.027
multi organism reproductive process GO:0044703 262 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
positive regulation of cell communication GO:0010647 271 0.026
cytoskeleton organization GO:0007010 111 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
metal ion transport GO:0030001 289 0.026
cellular protein localization GO:0034613 122 0.026
blood circulation GO:0008015 183 0.026
inorganic ion transmembrane transport GO:0098660 229 0.026
regulation of phosphorylation GO:0042325 248 0.025
positive regulation of neurogenesis GO:0050769 165 0.025
response to vitamin GO:0033273 131 0.025
cellular ketone metabolic process GO:0042180 51 0.025
cellular macromolecule localization GO:0070727 122 0.025
divalent metal ion transport GO:0070838 132 0.025
divalent inorganic cation homeostasis GO:0072507 165 0.025
regulation of cell projection organization GO:0031344 175 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
macromolecular complex assembly GO:0065003 273 0.025
defense response GO:0006952 194 0.025
response to wounding GO:0009611 254 0.025
protein transport GO:0015031 132 0.025
positive regulation of developmental process GO:0051094 283 0.025
neurological system process GO:0050877 219 0.025
localization of cell GO:0051674 202 0.025
negative regulation of cellular biosynthetic process GO:0031327 161 0.025
cellular calcium ion homeostasis GO:0006874 160 0.024
organelle organization GO:0006996 266 0.024
cell projection morphogenesis GO:0048858 123 0.024
cellular response to hormone stimulus GO:0032870 247 0.024
oxoacid metabolic process GO:0043436 290 0.024
purine nucleotide metabolic process GO:0006163 229 0.024
circulatory system process GO:0003013 183 0.024
positive regulation of nervous system development GO:0051962 178 0.024
ras protein signal transduction GO:0007265 29 0.024
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.024
nucleotide metabolic process GO:0009117 279 0.024
inorganic cation transmembrane transport GO:0098662 202 0.024
cation transmembrane transport GO:0098655 263 0.023
cellular divalent inorganic cation homeostasis GO:0072503 162 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
negative regulation of cell proliferation GO:0008285 119 0.023
cation homeostasis GO:0055080 195 0.023
protein phosphorylation GO:0006468 345 0.023
establishment of protein localization GO:0045184 141 0.023
regulation of metal ion transport GO:0010959 118 0.023
carboxylic acid metabolic process GO:0019752 289 0.023
tissue development GO:0009888 252 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
negative regulation of cell communication GO:0010648 158 0.023
hormone secretion GO:0046879 115 0.023
negative regulation of cell death GO:0060548 229 0.023
Human
immune response GO:0006955 104 0.023
organonitrogen compound catabolic process GO:1901565 179 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
cell part morphogenesis GO:0032990 123 0.022
reproductive system development GO:0061458 128 0.022
Rat
negative regulation of cell differentiation GO:0045596 99 0.022
amine metabolic process GO:0009308 38 0.022
nuclear transport GO:0051169 49 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
negative regulation of cell development GO:0010721 82 0.022
negative regulation of rna biosynthetic process GO:1902679 118 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
single organism catabolic process GO:0044712 283 0.022
response to peptide GO:1901652 292 0.022
catabolic process GO:0009056 351 0.022
transmembrane transport GO:0055085 412 0.021
positive regulation of secretion by cell GO:1903532 128 0.021
negative regulation of transcription dna templated GO:0045892 116 0.021
positive regulation of signaling GO:0023056 270 0.021
regulation of hydrolase activity GO:0051336 143 0.021
response to estrogen GO:0043627 232 0.021
single organism organelle organization GO:1902589 180 0.021
muscle system process GO:0003012 115 0.021
cellular response to lipid GO:0071396 201 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.020
cell motility GO:0048870 202 0.020
immune system process GO:0002376 204 0.020
negative regulation of nervous system development GO:0051961 79 0.020
gonad development GO:0008406 104 0.020
Rat
cellular metal ion homeostasis GO:0006875 172 0.020
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
anion transport GO:0006820 178 0.019
cardiovascular system development GO:0072358 134 0.019
regulation of hormone levels GO:0010817 187 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
Rat
cellular response to organonitrogen compound GO:0071417 197 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
regulation of protein metabolic process GO:0051246 289 0.019
neuron death GO:0070997 127 0.019
Human
regulation of cellular amine metabolic process GO:0033238 8 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
positive regulation of signal transduction GO:0009967 175 0.018
cell migration GO:0016477 197 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
intracellular protein transport GO:0006886 79 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
cellular catabolic process GO:0044248 295 0.018
regulation of growth GO:0040008 105 0.018
axis specification GO:0009798 4 0.018
negative regulation of neurogenesis GO:0050768 78 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
response to peptide hormone GO:0043434 278 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
protein oligomerization GO:0051259 191 0.017
cytoplasmic transport GO:0016482 115 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.017
regulation of protein localization GO:0032880 81 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
actin filament based process GO:0030029 86 0.017
muscle cell proliferation GO:0033002 84 0.017
negative regulation of developmental process GO:0051093 125 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
signal release GO:0023061 145 0.017
gastrulation GO:0007369 2 0.017
dendrite development GO:0016358 72 0.017
single organism biosynthetic process GO:0044711 342 0.017
response to radiation GO:0009314 137 0.016
action potential GO:0001508 54 0.016
mapk cascade GO:0000165 140 0.016
response to other organism GO:0051707 220 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
response to oxidative stress GO:0006979 186 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
regulation of hormone secretion GO:0046883 106 0.016
regulation of locomotion GO:0040012 148 0.016
dephosphorylation GO:0016311 98 0.016
response to acid chemical GO:0001101 222 0.016
heart morphogenesis GO:0003007 3 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
signal transduction by phosphorylation GO:0023014 144 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
Human
positive regulation of protein metabolic process GO:0051247 178 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
maintenance of location GO:0051235 17 0.015
calcium ion transport GO:0006816 131 0.015
aging GO:0007568 241 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.015
positive regulation of cell death GO:0010942 184 0.015
response to oxygen levels GO:0070482 265 0.015
sex differentiation GO:0007548 113 0.015
Rat
regulation of peptide transport GO:0090087 87 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
synaptic transmission GO:0007268 235 0.015
divalent inorganic cation transport GO:0072511 134 0.015
cell adhesion GO:0007155 110 0.015
multicellular organismal signaling GO:0035637 44 0.015
cellular response to organic cyclic compound GO:0071407 202 0.014
nucleotide catabolic process GO:0009166 139 0.014
response to tumor necrosis factor GO:0034612 56 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
sequestering of calcium ion GO:0051208 8 0.014
axonogenesis GO:0007409 71 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
response to purine containing compound GO:0014074 126 0.014
response to monosaccharide GO:0034284 159 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
vesicle mediated transport GO:0016192 181 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
positive regulation of secretion GO:0051047 140 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
purine containing compound catabolic process GO:0072523 138 0.014
nucleocytoplasmic transport GO:0006913 48 0.014
muscle structure development GO:0061061 87 0.014
amide transport GO:0042886 105 0.014
response to ketone GO:1901654 182 0.014
peptide secretion GO:0002790 86 0.014
regulation of anatomical structure size GO:0090066 135 0.014
forebrain development GO:0030900 98 0.014
organic substance catabolic process GO:1901575 316 0.014
cell type specific apoptotic process GO:0097285 134 0.014
Human
regulation of protein phosphorylation GO:0001932 183 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
actin cytoskeleton organization GO:0030036 73 0.013
regulation of homeostatic process GO:0032844 101 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
heart development GO:0007507 72 0.013
positive regulation of ion transport GO:0043270 94 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
Human
peptide transport GO:0015833 97 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
response to hypoxia GO:0001666 231 0.013
response to reactive oxygen species GO:0000302 120 0.013
gliogenesis GO:0042063 93 0.013
response to glucocorticoid GO:0051384 223 0.013
organophosphate catabolic process GO:0046434 148 0.013
regulation of catabolic process GO:0009894 113 0.013
lipid metabolic process GO:0006629 283 0.013
rhythmic process GO:0048511 156 0.013
regulation of response to stress GO:0080134 126 0.013
proteolysis GO:0006508 175 0.013
regulation of membrane potential GO:0042391 110 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
nucleoside metabolic process GO:0009116 179 0.013
heterocycle catabolic process GO:0046700 167 0.012
cardiac ventricle development GO:0003231 1 0.012
response to biotic stimulus GO:0009607 226 0.012
regulation of blood circulation GO:1903522 110 0.012
carboxylic acid transport GO:0046942 115 0.012
hormone transport GO:0009914 121 0.012
gamete generation GO:0007276 124 0.012
negative regulation of molecular function GO:0044092 133 0.012
positive regulation of protein modification process GO:0031401 142 0.012
establishment of tissue polarity GO:0007164 2 0.012
development of primary female sexual characteristics GO:0046545 56 0.012
Rat
second messenger mediated signaling GO:0019932 51 0.012
female pregnancy GO:0007565 122 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
developmental growth GO:0048589 100 0.012
multi multicellular organism process GO:0044706 138 0.012
taxis GO:0042330 67 0.012
sequestering of metal ion GO:0051238 9 0.012
response to insulin GO:0032868 133 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
regulation of response to external stimulus GO:0032101 106 0.012
anterior posterior pattern specification GO:0009952 1 0.012
lipid storage GO:0019915 1 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
regeneration GO:0031099 163 0.012
biological adhesion GO:0022610 110 0.012
spindle organization GO:0007051 2 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
organic hydroxy compound transport GO:0015850 77 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
response to external biotic stimulus GO:0043207 221 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
response to hexose GO:0009746 144 0.012
response to carbohydrate GO:0009743 183 0.012
negative regulation of neuron differentiation GO:0045665 62 0.011
cellular response to external stimulus GO:0071496 118 0.011
organic acid transport GO:0015849 116 0.011
rho protein signal transduction GO:0007266 11 0.011
cardiac chamber development GO:0003205 1 0.011
development of primary sexual characteristics GO:0045137 107 0.011
Rat
regulation of calcium ion transport GO:0051924 77 0.011
regulation of intracellular transport GO:0032386 65 0.011
male gamete generation GO:0048232 99 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
spermatogenesis GO:0007283 99 0.011
response to glucose GO:0009749 136 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
regulation of nucleocytoplasmic transport GO:0046822 28 0.011
cell growth GO:0016049 104 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
developmental process involved in reproduction GO:0003006 159 0.011
Rat
single organism cellular localization GO:1902580 102 0.011
negative regulation of signal transduction GO:0009968 83 0.011
chemotaxis GO:0006935 66 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
response to decreased oxygen levels GO:0036293 237 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
Human
regulation of cellular component biogenesis GO:0044087 86 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
carbohydrate metabolic process GO:0005975 130 0.011
cellular lipid metabolic process GO:0044255 208 0.011
cell cycle checkpoint GO:0000075 2 0.011
regulation of establishment of planar polarity GO:0090175 2 0.011
response to estradiol GO:0032355 164 0.011
female sex differentiation GO:0046660 59 0.011
Rat
ribonucleotide metabolic process GO:0009259 231 0.011
regulation of cell migration GO:0030334 128 0.011
peptide hormone secretion GO:0030072 84 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
embryonic pattern specification GO:0009880 1 0.010
regulation of protein transport GO:0051223 68 0.010
regulation of muscle system process GO:0090257 79 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
multicellular organism growth GO:0035264 1 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
striated muscle contraction GO:0006941 44 0.010
monosaccharide metabolic process GO:0005996 61 0.010
regulation of cell motility GO:2000145 131 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
peptidyl amino acid modification GO:0018193 126 0.010
muscle contraction GO:0006936 88 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
adult locomotory behavior GO:0008344 4 0.010
ovulation cycle GO:0042698 67 0.010
insulin secretion GO:0030073 69 0.010

Tox3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
cardiovascular system disease DOID:1287 0 0.019
central nervous system disease DOID:331 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
musculoskeletal system disease DOID:17 0 0.011