Rattus norvegicus

16 known processes

Mc2r

melanocortin 2 receptor

Mc2r biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.046
carboxylic acid metabolic process GO:0019752 289 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
oxoacid metabolic process GO:0043436 290 0.036
amine metabolic process GO:0009308 38 0.034
reproductive process GO:0022414 372 0.033
apoptotic process GO:0006915 381 0.031
cellular amine metabolic process GO:0044106 38 0.031
cellular ketone metabolic process GO:0042180 51 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
cellular component assembly GO:0022607 360 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
transmembrane transport GO:0055085 412 0.030
neuron differentiation GO:0030182 368 0.030
intracellular signal transduction GO:0035556 314 0.030
response to extracellular stimulus GO:0009991 380 0.029
regulation of molecular function GO:0065009 398 0.029
rna metabolic process GO:0016070 406 0.029
homeostatic process GO:0042592 331 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
regulation of rna metabolic process GO:0051252 391 0.028
nucleic acid templated transcription GO:0097659 379 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
programmed cell death GO:0012501 392 0.028
regulation of cell development GO:0060284 263 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
regulation of cell proliferation GO:0042127 359 0.027
cell projection organization GO:0030030 302 0.027
regulation of neurogenesis GO:0050767 247 0.026
central nervous system development GO:0007417 311 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
response to nutrient levels GO:0031667 370 0.026
cation transport GO:0006812 382 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.025
positive regulation of developmental process GO:0051094 283 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
regulation of cellular component organization GO:0051128 368 0.025
regulation of programmed cell death GO:0043067 341 0.025
transcription dna templated GO:0006351 377 0.025
neuron projection development GO:0031175 273 0.025
single organism reproductive process GO:0044702 297 0.025
single organism biosynthetic process GO:0044711 342 0.025
regulation of apoptotic process GO:0042981 335 0.025
protein phosphorylation GO:0006468 345 0.025
cellular component biogenesis GO:0044085 368 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
response to inorganic substance GO:0010035 377 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
regulation of nervous system development GO:0051960 264 0.024
regulation of transcription dna templated GO:0006355 374 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
macromolecular complex assembly GO:0065003 273 0.023
regulation of rna biosynthetic process GO:2001141 381 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
protein complex biogenesis GO:0070271 263 0.023
organophosphate metabolic process GO:0019637 370 0.023
rna biosynthetic process GO:0032774 380 0.023
cellular response to stress GO:0033554 269 0.023
nucleotide metabolic process GO:0009117 279 0.023
neuron development GO:0048666 286 0.023
regulation of cell differentiation GO:0045595 320 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.023
negative regulation of metabolic process GO:0009892 331 0.023
multi organism reproductive process GO:0044703 262 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
regulation of protein metabolic process GO:0051246 289 0.022
positive regulation of molecular function GO:0044093 230 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
regulation of signal transduction GO:0009966 318 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
positive regulation of cell communication GO:0010647 271 0.022
chemical homeostasis GO:0048878 292 0.021
regulation of catalytic activity GO:0050790 304 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
protein complex assembly GO:0006461 263 0.021
brain development GO:0007420 247 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
regulation of neuron differentiation GO:0045664 208 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
response to oxygen levels GO:0070482 265 0.021
secretion GO:0046903 307 0.020
organic substance catabolic process GO:1901575 316 0.020
metal ion transport GO:0030001 289 0.020
protein complex subunit organization GO:0071822 302 0.020
single organism catabolic process GO:0044712 283 0.020
regulation of phosphorylation GO:0042325 248 0.020
response to hypoxia GO:0001666 231 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
organelle organization GO:0006996 266 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
regulation of cellular localization GO:0060341 263 0.020
g protein coupled receptor signaling pathway GO:0007186 242 0.020
response to corticosteroid GO:0031960 235 0.020
head development GO:0060322 247 0.020
response to nutrient GO:0007584 248 0.020
cellular catabolic process GO:0044248 295 0.019
reproduction GO:0000003 245 0.019
transcription from rna polymerase ii promoter GO:0006366 252 0.019
ion transmembrane transport GO:0034220 365 0.019
neurological system process GO:0050877 219 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
catabolic process GO:0009056 351 0.019
purine containing compound metabolic process GO:0072521 253 0.019
cell cell signaling GO:0007267 335 0.019
response to ethanol GO:0045471 162 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
rhythmic process GO:0048511 156 0.019
positive regulation of gene expression GO:0010628 244 0.019
response to acid chemical GO:0001101 222 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
cellular homeostasis GO:0019725 252 0.018
response to oxidative stress GO:0006979 186 0.018
multicellular organism reproduction GO:0032504 233 0.018
regulation of neuron projection development GO:0010975 161 0.018
oxidation reduction process GO:0055114 304 0.018
response to glucocorticoid GO:0051384 223 0.018
response to peptide hormone GO:0043434 278 0.018
response to decreased oxygen levels GO:0036293 237 0.018
anion transport GO:0006820 178 0.018
response to ketone GO:1901654 182 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
secretion by cell GO:0032940 248 0.018
regulation of ion transport GO:0043269 245 0.018
ion homeostasis GO:0050801 212 0.018
cellular response to nitrogen compound GO:1901699 210 0.017
defense response GO:0006952 194 0.017
cellular chemical homeostasis GO:0055082 247 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
negative regulation of cell death GO:0060548 229 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
immune system process GO:0002376 204 0.017
response to peptide GO:1901652 292 0.017
positive regulation of cell development GO:0010720 176 0.017
nitrogen compound transport GO:0071705 229 0.017
response to wounding GO:0009611 254 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
blood circulation GO:0008015 183 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
negative regulation of gene expression GO:0010629 199 0.016
intracellular transport GO:0046907 185 0.016
positive regulation of nervous system development GO:0051962 178 0.016
macromolecule localization GO:0033036 252 0.016
aging GO:0007568 241 0.016
synaptic transmission GO:0007268 235 0.016
regulation of protein modification process GO:0031399 194 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
response to metal ion GO:0010038 253 0.016
response to estrogen GO:0043627 232 0.016
negative regulation of transport GO:0051051 136 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
regulation of secretion by cell GO:1903530 208 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
response to growth factor GO:0070848 189 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
metal ion homeostasis GO:0055065 186 0.016
inflammatory response GO:0006954 150 0.016
lipid metabolic process GO:0006629 283 0.016
regulation of cell projection organization GO:0031344 175 0.016
circulatory system process GO:0003013 183 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
cellular ion homeostasis GO:0006873 184 0.015
positive regulation of transport GO:0051050 245 0.015
protein oligomerization GO:0051259 191 0.015
response to radiation GO:0009314 137 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
cation homeostasis GO:0055080 195 0.015
response to cytokine GO:0034097 215 0.015
ras protein signal transduction GO:0007265 29 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
response to biotic stimulus GO:0009607 226 0.015
heart morphogenesis GO:0003007 3 0.015
regulation of system process GO:0044057 208 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
cellular cation homeostasis GO:0030003 180 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
gland development GO:0048732 155 0.015
sexual reproduction GO:0019953 148 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
single organism organelle organization GO:1902589 180 0.014
positive regulation of signaling GO:0023056 270 0.014
calcium ion homeostasis GO:0055074 162 0.014
cellular component movement GO:0006928 248 0.014
response to other organism GO:0051707 220 0.014
protein localization GO:0008104 191 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
response to vitamin GO:0033273 131 0.014
positive regulation of cell death GO:0010942 184 0.014
female pregnancy GO:0007565 122 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
heterocycle catabolic process GO:0046700 167 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
regulation of secretion GO:0051046 224 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
negative regulation of molecular function GO:0044092 133 0.014
response to lipopolysaccharide GO:0032496 191 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
response to external biotic stimulus GO:0043207 221 0.013
response to carbohydrate GO:0009743 183 0.013
proteolysis GO:0006508 175 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
developmental process involved in reproduction GO:0003006 159 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
regulation of hormone levels GO:0010817 187 0.013
regulation of membrane potential GO:0042391 110 0.013
response to estradiol GO:0032355 164 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
negative regulation of cell communication GO:0010648 158 0.013
response to toxic substance GO:0009636 133 0.013
single organism intracellular transport GO:1902582 166 0.013
negative regulation of signaling GO:0023057 157 0.013
cellular response to lipid GO:0071396 201 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
regeneration GO:0031099 163 0.013
nucleoside metabolic process GO:0009116 179 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
sex differentiation GO:0007548 113 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
response to bacterium GO:0009617 200 0.013
calcium ion transport GO:0006816 131 0.013
muscle system process GO:0003012 115 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
axis specification GO:0009798 4 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
cation transmembrane transport GO:0098655 263 0.013
cellular protein localization GO:0034613 122 0.013
cell morphogenesis GO:0000902 142 0.012
regulation of anatomical structure size GO:0090066 135 0.012
multi multicellular organism process GO:0044706 138 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
regulation of hydrolase activity GO:0051336 143 0.012
gamete generation GO:0007276 124 0.012
cellular component morphogenesis GO:0032989 155 0.012
growth GO:0040007 165 0.012
cellular lipid metabolic process GO:0044255 208 0.012
regulation of synaptic transmission GO:0050804 141 0.012
peptidyl amino acid modification GO:0018193 126 0.012
localization of cell GO:0051674 202 0.012
reproductive structure development GO:0048608 128 0.012
cardiovascular system development GO:0072358 134 0.012
signal release GO:0023061 145 0.012
divalent inorganic cation transport GO:0072511 134 0.012
locomotion GO:0040011 237 0.012
small molecule biosynthetic process GO:0044283 124 0.012
carbohydrate metabolic process GO:0005975 130 0.012
positive regulation of protein modification process GO:0031401 142 0.012
regulation of metal ion transport GO:0010959 118 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
positive regulation of signal transduction GO:0009967 175 0.012
immune response GO:0006955 104 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
divalent metal ion transport GO:0070838 132 0.012
anterior posterior pattern specification GO:0009952 1 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
cell migration GO:0016477 197 0.012
response to organophosphorus GO:0046683 102 0.011
development of primary sexual characteristics GO:0045137 107 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
negative regulation of developmental process GO:0051093 125 0.011
hormone secretion GO:0046879 115 0.011
regulation of neuron death GO:1901214 115 0.011
response to hexose GO:0009746 144 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
cytoplasmic transport GO:0016482 115 0.011
negative regulation of innate immune response GO:0045824 4 0.011
cellular response to peptide GO:1901653 133 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
response to reactive oxygen species GO:0000302 120 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
response to glucose GO:0009749 136 0.011
mapk cascade GO:0000165 140 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
purine containing compound catabolic process GO:0072523 138 0.011
tissue development GO:0009888 252 0.011
aromatic compound catabolic process GO:0019439 168 0.011
regulation of transferase activity GO:0051338 123 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
amide transport GO:0042886 105 0.011
regulation of kinase activity GO:0043549 117 0.011
cell part morphogenesis GO:0032990 123 0.011
eye morphogenesis GO:0048592 4 0.011
regulation of immune system process GO:0002682 123 0.011
circulatory system development GO:0072359 134 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
cell motility GO:0048870 202 0.011
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.011
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.011
male gamete generation GO:0048232 99 0.011
spermatogenesis GO:0007283 99 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
response to alkaloid GO:0043279 132 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
organic anion transport GO:0015711 132 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
organophosphate catabolic process GO:0046434 148 0.011
lipid storage GO:0019915 1 0.011
regulation of response to stress GO:0080134 126 0.011
embryonic skeletal system development GO:0048706 3 0.010
hormone transport GO:0009914 121 0.010
action potential GO:0001508 54 0.010
response to monosaccharide GO:0034284 159 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
lipid biosynthetic process GO:0008610 128 0.010
regulation of cytokine biosynthetic process GO:0042035 3 0.010
response to camp GO:0051591 91 0.010
organic acid transport GO:0015849 116 0.010
negative regulation of cell proliferation GO:0008285 119 0.010
cellular macromolecule localization GO:0070727 122 0.010
response to purine containing compound GO:0014074 126 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
chromosome segregation GO:0007059 2 0.010
sensory perception GO:0007600 101 0.010
nucleotide catabolic process GO:0009166 139 0.010
cell projection morphogenesis GO:0048858 123 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
response to insulin GO:0032868 133 0.010
regulation of protein kinase activity GO:0045859 105 0.010
regulation of catabolic process GO:0009894 113 0.010
behavior GO:0007610 205 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
actin filament based process GO:0030029 86 0.010
dna metabolic process GO:0006259 96 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
protein transport GO:0015031 132 0.010
peptide transport GO:0015833 97 0.010
reproductive system development GO:0061458 128 0.010

Mc2r disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.021
disease of metabolism DOID:0014667 0 0.015
central nervous system disease DOID:331 0 0.012
musculoskeletal system disease DOID:17 0 0.011
sensory system disease DOID:0050155 0 0.011