Rattus norvegicus

6 known processes

Clta

clathrin, light chain (Lca)

(Aliases: LCA1,LCA2,LCA3,MGC105384)

Clta biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of programmed cell death GO:0043067 341 0.169
vesicle mediated transport GO:0016192 181 0.153
regulation of apoptotic process GO:0042981 335 0.131
single organism intracellular transport GO:1902582 166 0.118
response to peptide GO:1901652 292 0.112
regulation of cellular component organization GO:0051128 368 0.112
programmed cell death GO:0012501 392 0.104
response to peptide hormone GO:0043434 278 0.099
reproductive process GO:0022414 372 0.099
macromolecular complex subunit organization GO:0043933 339 0.097
regulation of protein metabolic process GO:0051246 289 0.095
macromolecule localization GO:0033036 252 0.094
single organism reproductive process GO:0044702 297 0.092
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.090
intracellular transport GO:0046907 185 0.089
cell morphogenesis involved in differentiation GO:0000904 119 0.089
regulation of signal transduction GO:0009966 318 0.087
regulation of multicellular organismal development GO:2000026 376 0.086
response to insulin GO:0032868 133 0.086
cellular component biogenesis GO:0044085 368 0.085
regulation of neuron differentiation GO:0045664 208 0.082
protein complex biogenesis GO:0070271 263 0.079
regulation of cell differentiation GO:0045595 320 0.079
central nervous system development GO:0007417 311 0.078
cellular response to oxygen containing compound GO:1901701 386 0.077
positive regulation of multicellular organismal process GO:0051240 387 0.072
negative regulation of macromolecule metabolic process GO:0010605 260 0.071
negative regulation of metabolic process GO:0009892 331 0.071
protein localization GO:0008104 191 0.070
macromolecular complex assembly GO:0065003 273 0.069
homeostatic process GO:0042592 331 0.069
cell projection morphogenesis GO:0048858 123 0.068
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.067
positive regulation of cellular component organization GO:0051130 200 0.066
response to extracellular stimulus GO:0009991 380 0.066
cellular response to peptide hormone stimulus GO:0071375 120 0.065
cation transport GO:0006812 382 0.065
cell projection organization GO:0030030 302 0.063
multi organism reproductive process GO:0044703 262 0.063
response to nutrient levels GO:0031667 370 0.062
regulation of molecular function GO:0065009 398 0.062
apoptotic process GO:0006915 381 0.060
organic acid metabolic process GO:0006082 292 0.059
negative regulation of cell death GO:0060548 229 0.058
negative regulation of apoptotic process GO:0043066 181 0.057
regulation of intracellular signal transduction GO:1902531 218 0.057
response to external biotic stimulus GO:0043207 221 0.055
regulation of neurogenesis GO:0050767 247 0.055
anatomical structure morphogenesis GO:0009653 298 0.054
positive regulation of developmental process GO:0051094 283 0.054
cellular macromolecule localization GO:0070727 122 0.053
cellular component assembly GO:0022607 360 0.052
positive regulation of phosphate metabolic process GO:0045937 262 0.050
neuron projection development GO:0031175 273 0.050
positive regulation of cell differentiation GO:0045597 217 0.049
cellular cation homeostasis GO:0030003 180 0.048
intracellular signal transduction GO:0035556 314 0.048
negative regulation of cellular metabolic process GO:0031324 281 0.047
regulation of nervous system development GO:0051960 264 0.047
regulation of anatomical structure morphogenesis GO:0022603 141 0.046
regulation of anatomical structure size GO:0090066 135 0.046
cellular component morphogenesis GO:0032989 155 0.046
protein complex assembly GO:0006461 263 0.046
positive regulation of response to stimulus GO:0048584 285 0.045
cellular response to endogenous stimulus GO:0071495 377 0.045
neuron development GO:0048666 286 0.044
ion transmembrane transport GO:0034220 365 0.044
positive regulation of cell communication GO:0010647 271 0.044
positive regulation of phosphorus metabolic process GO:0010562 262 0.044
cell morphogenesis GO:0000902 142 0.043
cellular response to nitrogen compound GO:1901699 210 0.043
reproduction GO:0000003 245 0.043
positive regulation of signal transduction GO:0009967 175 0.043
cellular response to organic cyclic compound GO:0071407 202 0.043
catabolic process GO:0009056 351 0.043
neuron differentiation GO:0030182 368 0.042
protein complex subunit organization GO:0071822 302 0.042
organelle organization GO:0006996 266 0.042
cellular response to hormone stimulus GO:0032870 247 0.042
response to bacterium GO:0009617 200 0.042
axon development GO:0061564 96 0.041
developmental process involved in reproduction GO:0003006 159 0.041
multicellular organismal reproductive process GO:0048609 233 0.041
regulation of phosphate metabolic process GO:0019220 349 0.040
cellular component movement GO:0006928 248 0.040
multicellular organism reproduction GO:0032504 233 0.040
regulation of cell proliferation GO:0042127 359 0.040
rhythmic process GO:0048511 156 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.039
cell type specific apoptotic process GO:0097285 134 0.039
positive regulation of cell proliferation GO:0008284 249 0.039
oxoacid metabolic process GO:0043436 290 0.038
cellular homeostasis GO:0019725 252 0.038
amine metabolic process GO:0009308 38 0.038
carboxylic acid metabolic process GO:0019752 289 0.038
response to biotic stimulus GO:0009607 226 0.038
head development GO:0060322 247 0.037
response to growth factor GO:0070848 189 0.037
positive regulation of signaling GO:0023056 270 0.037
nitrogen compound transport GO:0071705 229 0.037
cellular chemical homeostasis GO:0055082 247 0.037
protein phosphorylation GO:0006468 345 0.037
chemical homeostasis GO:0048878 292 0.036
regulation of neuron projection development GO:0010975 161 0.036
regulation of catabolic process GO:0009894 113 0.036
cellular response to growth factor stimulus GO:0071363 162 0.036
regulation of phosphorus metabolic process GO:0051174 349 0.036
regulation of neuron death GO:1901214 115 0.035
regulation of cellular protein metabolic process GO:0032268 267 0.034
negative regulation of gene expression GO:0010629 199 0.034
positive regulation of molecular function GO:0044093 230 0.034
metal ion transport GO:0030001 289 0.034
enzyme linked receptor protein signaling pathway GO:0007167 116 0.034
cation transmembrane transport GO:0098655 263 0.034
female pregnancy GO:0007565 122 0.033
response to nutrient GO:0007584 248 0.033
growth GO:0040007 165 0.032
negative regulation of protein metabolic process GO:0051248 114 0.032
cellular catabolic process GO:0044248 295 0.032
regulation of catalytic activity GO:0050790 304 0.032
glial cell differentiation GO:0010001 65 0.031
proteolysis GO:0006508 175 0.031
negative regulation of multicellular organismal process GO:0051241 203 0.031
response to other organism GO:0051707 220 0.031
positive regulation of protein metabolic process GO:0051247 178 0.031
neuron death GO:0070997 127 0.031
cellular ion homeostasis GO:0006873 184 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
cell part morphogenesis GO:0032990 123 0.030
negative regulation of rna biosynthetic process GO:1902679 118 0.029
response to acid chemical GO:0001101 222 0.029
regulation of cellular localization GO:0060341 263 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.028
regulation of growth GO:0040008 105 0.028
regulation of cell projection organization GO:0031344 175 0.027
developmental growth GO:0048589 100 0.027
response to ethanol GO:0045471 162 0.027
lipid metabolic process GO:0006629 283 0.027
axonogenesis GO:0007409 71 0.026
regulation of vesicle mediated transport GO:0060627 81 0.026
regulation of hormone levels GO:0010817 187 0.026
multicellular organism growth GO:0035264 1 0.026
neuron apoptotic process GO:0051402 88 0.026
negative regulation of biosynthetic process GO:0009890 168 0.026
response to estrogen GO:0043627 232 0.025
membrane organization GO:0061024 94 0.025
positive regulation of transport GO:0051050 245 0.025
cellular response to peptide GO:1901653 133 0.025
cellular amine metabolic process GO:0044106 38 0.025
inorganic ion transmembrane transport GO:0098660 229 0.025
cell cell signaling GO:0007267 335 0.025
response to inorganic substance GO:0010035 377 0.025
brain development GO:0007420 247 0.024
organonitrogen compound catabolic process GO:1901565 179 0.024
cell cycle GO:0007049 101 0.024
neuron projection morphogenesis GO:0048812 122 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.024
response to oxygen levels GO:0070482 265 0.024
rna biosynthetic process GO:0032774 380 0.024
inorganic cation transmembrane transport GO:0098662 202 0.024
gliogenesis GO:0042063 93 0.024
response to hypoxia GO:0001666 231 0.024
protein oligomerization GO:0051259 191 0.024
regulation of axonogenesis GO:0050770 37 0.023
positive regulation of catalytic activity GO:0043085 184 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
multicellular organismal homeostasis GO:0048871 49 0.023
sexual reproduction GO:0019953 148 0.023
negative regulation of nucleic acid templated transcription GO:1903507 117 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
regulation of transcription dna templated GO:0006355 374 0.022
positive regulation of intracellular signal transduction GO:1902533 138 0.022
multi multicellular organism process GO:0044706 138 0.022
cell cycle process GO:0022402 57 0.022
rna metabolic process GO:0016070 406 0.022
establishment of protein localization GO:0045184 141 0.022
single organism catabolic process GO:0044712 283 0.022
regulation of rna metabolic process GO:0051252 391 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
positive regulation of cell death GO:0010942 184 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
response to molecule of bacterial origin GO:0002237 194 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
nucleic acid templated transcription GO:0097659 379 0.021
negative regulation of programmed cell death GO:0043069 183 0.021
cellular response to organonitrogen compound GO:0071417 197 0.021
behavior GO:0007610 205 0.021
response to glucocorticoid GO:0051384 223 0.021
response to transition metal nanoparticle GO:1990267 122 0.020
metal ion homeostasis GO:0055065 186 0.020
sulfur compound metabolic process GO:0006790 70 0.020
response to toxic substance GO:0009636 133 0.020
regulation of membrane potential GO:0042391 110 0.020
positive regulation of cell development GO:0010720 176 0.020
immune system process GO:0002376 204 0.020
positive regulation of protein modification process GO:0031401 142 0.020
negative regulation of cellular component organization GO:0051129 83 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
muscle contraction GO:0006936 88 0.019
cell adhesion GO:0007155 110 0.019
blood circulation GO:0008015 183 0.019
regulation of hydrolase activity GO:0051336 143 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
cellular response to lipid GO:0071396 201 0.019
gamete generation GO:0007276 124 0.018
positive regulation of nervous system development GO:0051962 178 0.018
cellular ketone metabolic process GO:0042180 51 0.018
negative regulation of cell communication GO:0010648 158 0.018
neurological system process GO:0050877 219 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
endocytosis GO:0006897 84 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
regulation of peptidase activity GO:0052547 55 0.018
inflammatory response GO:0006954 150 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
cellular lipid metabolic process GO:0044255 208 0.017
response to metal ion GO:0010038 253 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
anion transport GO:0006820 178 0.017
action potential GO:0001508 54 0.017
cellular protein localization GO:0034613 122 0.017
protein maturation GO:0051604 68 0.017
response to carbohydrate GO:0009743 183 0.017
defense response GO:0006952 194 0.017
cytoplasmic transport GO:0016482 115 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
cellular response to alcohol GO:0097306 87 0.017
ribose phosphate metabolic process GO:0019693 235 0.016
organophosphate metabolic process GO:0019637 370 0.016
negative regulation of signaling GO:0023057 157 0.016
transmembrane transport GO:0055085 412 0.016
regulation of mapk cascade GO:0043408 116 0.016
negative regulation of transport GO:0051051 136 0.016
response to wounding GO:0009611 254 0.016
nucleotide metabolic process GO:0009117 279 0.016
ion homeostasis GO:0050801 212 0.016
tissue development GO:0009888 252 0.016
mapk cascade GO:0000165 140 0.016
response to decreased oxygen levels GO:0036293 237 0.015
response to retinoic acid GO:0032526 63 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
organic anion transport GO:0015711 132 0.015
negative regulation of cell proliferation GO:0008285 119 0.015
response to lipopolysaccharide GO:0032496 191 0.015
regulation of cell growth GO:0001558 85 0.015
protein processing GO:0016485 68 0.015
regulation of developmental growth GO:0048638 45 0.015
cellular amide metabolic process GO:0043603 44 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
response to purine containing compound GO:0014074 126 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
carboxylic acid transport GO:0046942 115 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
reproductive structure development GO:0048608 128 0.015
cell growth GO:0016049 104 0.015
response to corticosteroid GO:0031960 235 0.014
cellular response to insulin stimulus GO:0032869 81 0.014
cellular response to stress GO:0033554 269 0.014
gonad development GO:0008406 104 0.014
regulation of phosphorylation GO:0042325 248 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
regulation of proteolysis GO:0030162 66 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
single organism biosynthetic process GO:0044711 342 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
purine containing compound catabolic process GO:0072523 138 0.014
regulation of ion transport GO:0043269 245 0.014
organic substance catabolic process GO:1901575 316 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
neuronal action potential GO:0019228 35 0.014
circulatory system process GO:0003013 183 0.013
gland development GO:0048732 155 0.013
regulation of kinase activity GO:0043549 117 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
regulation of cell development GO:0060284 263 0.013
sensory organ development GO:0007423 74 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
cellular response to external stimulus GO:0071496 118 0.013
protein transport GO:0015031 132 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
development of primary sexual characteristics GO:0045137 107 0.013
dendrite development GO:0016358 72 0.012
localization of cell GO:0051674 202 0.012
regulation of secretion GO:0051046 224 0.012
regulation of system process GO:0044057 208 0.012
synaptic transmission GO:0007268 235 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
ossification GO:0001503 70 0.012
reproductive system development GO:0061458 128 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
cell migration GO:0016477 197 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
neuron projection guidance GO:0097485 24 0.012
biological adhesion GO:0022610 110 0.012
hair cell differentiation GO:0035315 2 0.012
negative regulation of signal transduction GO:0009968 83 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
cell motility GO:0048870 202 0.012
lipid transport GO:0006869 61 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
negative regulation of molecular function GO:0044092 133 0.012
transcription dna templated GO:0006351 377 0.012
response to oxidative stress GO:0006979 186 0.012
purine containing compound metabolic process GO:0072521 253 0.011
sensory perception GO:0007600 101 0.011
nucleotide catabolic process GO:0009166 139 0.011
oxidation reduction process GO:0055114 304 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
regulation of endocytosis GO:0030100 42 0.011
signal release GO:0023061 145 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
taxis GO:0042330 67 0.011
cation homeostasis GO:0055080 195 0.011
epithelial cell differentiation GO:0030855 71 0.011
ameboidal type cell migration GO:0001667 26 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
calcium ion homeostasis GO:0055074 162 0.011
regulation of transferase activity GO:0051338 123 0.011
regulation of notch signaling pathway GO:0008593 3 0.011
regulation of protein modification process GO:0031399 194 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
embryo implantation GO:0007566 15 0.011
carbohydrate metabolic process GO:0005975 130 0.011
epithelium development GO:0060429 96 0.011
intracellular protein transport GO:0006886 79 0.011
salivary gland morphogenesis GO:0007435 1 0.011
regulation of response to stress GO:0080134 126 0.011
regulation of cellular component size GO:0032535 51 0.011
male gamete generation GO:0048232 99 0.010
regulation of protein kinase activity GO:0045859 105 0.010
anion transmembrane transport GO:0098656 77 0.010
protein heterooligomerization GO:0051291 89 0.010
ras protein signal transduction GO:0007265 29 0.010
spermatogenesis GO:0007283 99 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
innate immune response GO:0045087 35 0.010
rna localization GO:0006403 4 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
negative regulation of developmental process GO:0051093 125 0.010

Clta disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037
musculoskeletal system disease DOID:17 0 0.013
sensory system disease DOID:0050155 0 0.010