Rattus norvegicus

0 known processes

Tufm

Tu translation elongation factor, mitochondrial

Tufm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dicarboxylic acid catabolic process GO:0043649 1 0.536
dicarboxylic acid metabolic process GO:0043648 42 0.479
cofactor metabolic process GO:0051186 95 0.386
coenzyme metabolic process GO:0006732 86 0.377
nicotinamide nucleotide metabolic process GO:0046496 28 0.335
regulation of apoptotic process GO:0042981 335 0.208
organic acid metabolic process GO:0006082 292 0.202
carboxylic acid metabolic process GO:0019752 289 0.197
acyl coa metabolic process GO:0006637 28 0.189
generation of precursor metabolites and energy GO:0006091 62 0.160
2 oxoglutarate metabolic process GO:0006103 6 0.143
oxidation reduction process GO:0055114 304 0.135
oxoacid metabolic process GO:0043436 290 0.132
cellular amino acid metabolic process GO:0006520 107 0.116
pyridine containing compound metabolic process GO:0072524 32 0.111
oxaloacetate metabolic process GO:0006107 6 0.110
regulation of intracellular signal transduction GO:1902531 218 0.107
response to molecule of bacterial origin GO:0002237 194 0.086
tricarboxylic acid metabolic process GO:0072350 10 0.085
oxidoreduction coenzyme metabolic process GO:0006733 31 0.085
response to oxidative stress GO:0006979 186 0.083
nucleotide metabolic process GO:0009117 279 0.081
Yeast
cellular response to oxidative stress GO:0034599 76 0.079
cellular amino acid biosynthetic process GO:0008652 32 0.076
nucleobase containing small molecule metabolic process GO:0055086 316 0.070
Yeast
programmed cell death GO:0012501 392 0.068
energy derivation by oxidation of organic compounds GO:0015980 46 0.064
organophosphate metabolic process GO:0019637 370 0.063
Yeast
cellular respiration GO:0045333 21 0.062
nucleoside phosphate metabolic process GO:0006753 283 0.061
Yeast
regulation of phosphorylation GO:0042325 248 0.057
glutamine family amino acid biosynthetic process GO:0009084 2 0.057
regulation of programmed cell death GO:0043067 341 0.056
positive regulation of programmed cell death GO:0043068 157 0.054
carbohydrate catabolic process GO:0016052 40 0.051
glutamate metabolic process GO:0006536 3 0.050
response to temperature stimulus GO:0009266 94 0.050
single organism biosynthetic process GO:0044711 342 0.049
Yeast
cellular response to stress GO:0033554 269 0.047
pyridine nucleotide metabolic process GO:0019362 28 0.044
multicellular organismal reproductive process GO:0048609 233 0.044
nadh metabolic process GO:0006734 10 0.041
intracellular signal transduction GO:0035556 314 0.041
cellular homeostasis GO:0019725 252 0.040
reproductive process GO:0022414 372 0.038
cation transport GO:0006812 382 0.038
regulation of protein metabolic process GO:0051246 289 0.038
cellular response to oxygen containing compound GO:1901701 386 0.036
negative regulation of cell communication GO:0010648 158 0.035
response to peptide hormone GO:0043434 278 0.034
cation homeostasis GO:0055080 195 0.034
carbohydrate metabolic process GO:0005975 130 0.034
regulation of phosphorus metabolic process GO:0051174 349 0.033
protein processing GO:0016485 68 0.033
protein maturation GO:0051604 68 0.033
synaptic transmission GO:0007268 235 0.033
negative regulation of intracellular signal transduction GO:1902532 38 0.032
protein phosphorylation GO:0006468 345 0.032
regulation of neurogenesis GO:0050767 247 0.031
nad metabolic process GO:0019674 15 0.031
regulation of cell development GO:0060284 263 0.031
head development GO:0060322 247 0.031
regulation of nervous system development GO:0051960 264 0.030
positive regulation of signal transduction GO:0009967 175 0.029
feeding behavior GO:0007631 53 0.029
response to nutrient levels GO:0031667 370 0.028
female pregnancy GO:0007565 122 0.028
gonad development GO:0008406 104 0.028
response to corticosteroid GO:0031960 235 0.028
cellular response to reactive oxygen species GO:0034614 55 0.027
response to reactive oxygen species GO:0000302 120 0.027
apoptotic process GO:0006915 381 0.027
single organism catabolic process GO:0044712 283 0.027
Yeast
positive regulation of cell death GO:0010942 184 0.027
alpha amino acid biosynthetic process GO:1901607 23 0.026
response to toxic substance GO:0009636 133 0.026
homeostatic process GO:0042592 331 0.026
regulation of signal transduction GO:0009966 318 0.025
developmental process involved in reproduction GO:0003006 159 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
regulation of phosphate metabolic process GO:0019220 349 0.024
monocarboxylic acid metabolic process GO:0032787 152 0.024
proteolysis GO:0006508 175 0.024
ion homeostasis GO:0050801 212 0.024
regulation of kinase activity GO:0043549 117 0.023
mapk cascade GO:0000165 140 0.023
glutamate catabolic process GO:0006538 1 0.023
response to lipopolysaccharide GO:0032496 191 0.023
single organism reproductive process GO:0044702 297 0.023
regulation of response to stress GO:0080134 126 0.022
negative regulation of signaling GO:0023057 157 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
reproductive structure development GO:0048608 128 0.021
brain development GO:0007420 247 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
response to extracellular stimulus GO:0009991 380 0.021
alpha amino acid metabolic process GO:1901605 71 0.021
central nervous system development GO:0007417 311 0.021
regulation of molecular function GO:0065009 398 0.020
monovalent inorganic cation transport GO:0015672 172 0.020
cellular metal ion homeostasis GO:0006875 172 0.020
negative regulation of cell death GO:0060548 229 0.020
negative regulation of signal transduction GO:0009968 83 0.020
response to nutrient GO:0007584 248 0.020
mitochondrion organization GO:0007005 35 0.020
Yeast
glutamine family amino acid metabolic process GO:0009064 15 0.019
positive regulation of cell communication GO:0010647 271 0.019
regulation of cell proliferation GO:0042127 359 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
cellular component biogenesis GO:0044085 368 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
transcription dna templated GO:0006351 377 0.018
negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902176 2 0.018
development of primary sexual characteristics GO:0045137 107 0.018
catabolic process GO:0009056 351 0.018
Yeast
circulatory system process GO:0003013 183 0.018
cell migration GO:0016477 197 0.018
regulation of hydrolase activity GO:0051336 143 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
protein complex biogenesis GO:0070271 263 0.018
response to activity GO:0014823 73 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
Yeast
cellular cation homeostasis GO:0030003 180 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
gamete generation GO:0007276 124 0.017
multi organism reproductive process GO:0044703 262 0.017
response to peptide GO:1901652 292 0.017
response to bacterium GO:0009617 200 0.016
small molecule biosynthetic process GO:0044283 124 0.016
tricarboxylic acid cycle GO:0006099 11 0.016
organic substance catabolic process GO:1901575 316 0.016
Yeast
positive regulation of phosphate metabolic process GO:0045937 262 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
regulation of ion transport GO:0043269 245 0.016
growth GO:0040007 165 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
positive regulation of immune system process GO:0002684 90 0.015
multicellular organism reproduction GO:0032504 233 0.015
chemical homeostasis GO:0048878 292 0.015
regeneration GO:0031099 163 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
cellular ketone metabolic process GO:0042180 51 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
response to acid chemical GO:0001101 222 0.015
ion transmembrane transport GO:0034220 365 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
Yeast
thioester metabolic process GO:0035383 28 0.015
metal ion homeostasis GO:0055065 186 0.015
alpha amino acid catabolic process GO:1901606 20 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
immune system process GO:0002376 204 0.014
activation of cysteine type endopeptidase activity GO:0097202 4 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
cellular component assembly GO:0022607 360 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
cellular amine metabolic process GO:0044106 38 0.014
amine metabolic process GO:0009308 38 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
Yeast
multi multicellular organism process GO:0044706 138 0.014
brain renin angiotensin system GO:0002035 3 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
purine containing compound metabolic process GO:0072521 253 0.014
Yeast
regulation of multicellular organismal development GO:2000026 376 0.014
nucleoside metabolic process GO:0009116 179 0.014
Yeast
organic acid biosynthetic process GO:0016053 83 0.014
response to estrogen GO:0043627 232 0.013
sex differentiation GO:0007548 113 0.013
cell projection organization GO:0030030 302 0.013
cellular amino acid catabolic process GO:0009063 21 0.013
response to inorganic substance GO:0010035 377 0.013
organic acid catabolic process GO:0016054 49 0.013
rna metabolic process GO:0016070 406 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
Yeast
positive regulation of signaling GO:0023056 270 0.013
regulation of neuron differentiation GO:0045664 208 0.013
cellular ion homeostasis GO:0006873 184 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
cellular chemical homeostasis GO:0055082 247 0.012
positive regulation of cell development GO:0010720 176 0.012
regulation of growth GO:0040008 105 0.012
response to decreased oxygen levels GO:0036293 237 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
positive regulation of developmental process GO:0051094 283 0.012
response to oxygen levels GO:0070482 265 0.012
protein complex assembly GO:0006461 263 0.012
regulation of cellular component organization GO:0051128 368 0.011
metal ion transport GO:0030001 289 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
ras protein signal transduction GO:0007265 29 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
liver development GO:0001889 90 0.011
apoptotic signaling pathway GO:0097190 27 0.011
regulation of peptidase activity GO:0052547 55 0.011
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.011
cellular response to lipid GO:0071396 201 0.011
cell cell signaling GO:0007267 335 0.011
response to organophosphorus GO:0046683 102 0.011
regulation of system process GO:0044057 208 0.011
response to mechanical stimulus GO:0009612 134 0.010
macromolecular complex subunit organization GO:0043933 339 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
cellular response to alcohol GO:0097306 87 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
endocytosis GO:0006897 84 0.010

Tufm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
disease of metabolism DOID:0014667 0 0.024
cancer DOID:162 0 0.021
disease of cellular proliferation DOID:14566 0 0.021
central nervous system disease DOID:331 0 0.020
retinal disease DOID:5679 0 0.015
retinal degeneration DOID:8466 0 0.015
sensory system disease DOID:0050155 0 0.015
retinitis pigmentosa DOID:10584 0 0.015
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
organ system cancer DOID:0050686 0 0.012