Rattus norvegicus

71 known processes

Mink1

misshapen-like kinase 1 (zebrafish)

Mink1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
nucleic acid templated transcription GO:0097659 379 0.214
regulation of nucleic acid templated transcription GO:1903506 380 0.147
rna biosynthetic process GO:0032774 380 0.140
regulation of rna biosynthetic process GO:2001141 381 0.085
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.072
regulation of nervous system development GO:0051960 264 0.072
lipid metabolic process GO:0006629 283 0.068
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.060
transcription dna templated GO:0006351 377 0.056
single organism behavior GO:0044708 130 0.054
synaptic growth at neuromuscular junction GO:0051124 1 0.051
reproductive process GO:0022414 372 0.050
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.050
multicellular organism reproduction GO:0032504 233 0.049
rna metabolic process GO:0016070 406 0.049
regulation of rna metabolic process GO:0051252 391 0.048
locomotory exploration behavior GO:0035641 1 0.048
protein localization GO:0008104 191 0.047
exploration behavior GO:0035640 1 0.043
reproduction GO:0000003 245 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
positive regulation of transcription dna templated GO:0045893 197 0.038
lipid modification GO:0030258 52 0.037
transcription from rna polymerase ii promoter GO:0006366 252 0.037
synapse assembly GO:0007416 29 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
regulation of multicellular organismal development GO:2000026 376 0.035
regulation of cell projection organization GO:0031344 175 0.034
regulation of transcription dna templated GO:0006355 374 0.033
neurotransmitter gated ion channel clustering GO:0072578 3 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
brain development GO:0007420 247 0.033
cellular component assembly GO:0022607 360 0.033
programmed cell death GO:0012501 392 0.031
tube formation GO:0035148 3 0.030
cytoskeleton organization GO:0007010 111 0.029
regulation of cell development GO:0060284 263 0.029
negative regulation of metabolic process GO:0009892 331 0.027
n methyl d aspartate receptor clustering GO:0097114 2 0.027
single organism reproductive process GO:0044702 297 0.027
sexual reproduction GO:0019953 148 0.026
gamete generation GO:0007276 124 0.026
positive regulation of rna biosynthetic process GO:1902680 197 0.026
cellular component biogenesis GO:0044085 368 0.025
apoptotic process GO:0006915 381 0.025
positive regulation of developmental process GO:0051094 283 0.025
ion transmembrane transport GO:0034220 365 0.025
multicellular organismal reproductive process GO:0048609 233 0.024
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.023
immune system process GO:0002376 204 0.023
Mouse
organelle organization GO:0006996 266 0.023
negative regulation of rna biosynthetic process GO:1902679 118 0.023
multi organism reproductive process GO:0044703 262 0.022
regulation of molecular function GO:0065009 398 0.022
spindle organization GO:0007051 2 0.022
negative regulation of transport GO:0051051 136 0.022
regulation of cell differentiation GO:0045595 320 0.022
regulation of neuron projection development GO:0010975 161 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
phospholipid metabolic process GO:0006644 61 0.021
developmental growth GO:0048589 100 0.021
regulation of protein metabolic process GO:0051246 289 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
developmental process involved in reproduction GO:0003006 159 0.020
forebrain development GO:0030900 98 0.019
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 2 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
spermatogenesis GO:0007283 99 0.019
regulation of cytoskeleton organization GO:0051493 49 0.018
regulation of behavior GO:0050795 61 0.018
cellular component movement GO:0006928 248 0.018
regulation of ion transport GO:0043269 245 0.018
regulation of growth GO:0040008 105 0.018
chromatin assembly or disassembly GO:0006333 1 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
positive regulation of biosynthetic process GO:0009891 319 0.017
grooming behavior GO:0007625 4 0.017
negative regulation of rna metabolic process GO:0051253 123 0.017
response to metal ion GO:0010038 253 0.017
locomotion GO:0040011 237 0.017
blood circulation GO:0008015 183 0.017
dendritic spine organization GO:0097061 12 0.017
catabolic process GO:0009056 351 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
neuron death GO:0070997 127 0.016
regulation of neurogenesis GO:0050767 247 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
protein complex assembly GO:0006461 263 0.016
response to nutrient levels GO:0031667 370 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
negative regulation of cellular component organization GO:0051129 83 0.016
macromolecule localization GO:0033036 252 0.016
regulation of signal transduction GO:0009966 318 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
behavior GO:0007610 205 0.015
positive regulation of transport GO:0051050 245 0.015
morphogenesis of embryonic epithelium GO:0016331 3 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.014
regulation of neuron differentiation GO:0045664 208 0.014
male gamete generation GO:0048232 99 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
dendritic spine morphogenesis GO:0060997 9 0.014
regulation of behavioral fear response GO:2000822 3 0.014
regulation of cellular component organization GO:0051128 368 0.014
ras protein signal transduction GO:0007265 29 0.014
glycerolipid metabolic process GO:0046486 67 0.014
amine metabolic process GO:0009308 38 0.014
cellular lipid metabolic process GO:0044255 208 0.014
defense response GO:0006952 194 0.014
regeneration GO:0031099 163 0.014
nucleotide metabolic process GO:0009117 279 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
chemosensory behavior GO:0007635 2 0.013
positive regulation of gene expression GO:0010628 244 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
axis specification GO:0009798 4 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
anterior posterior pattern specification GO:0009952 1 0.013
cell projection organization GO:0030030 302 0.013
regulation of synapse assembly GO:0051963 15 0.013
cellular component morphogenesis GO:0032989 155 0.013
central nervous system development GO:0007417 311 0.013
response to nutrient GO:0007584 248 0.013
cellular protein localization GO:0034613 122 0.013
cellular amine metabolic process GO:0044106 38 0.013
head development GO:0060322 247 0.013
chromosome segregation GO:0007059 2 0.013
negative regulation of cell communication GO:0010648 158 0.013
response to inorganic substance GO:0010035 377 0.013
response to vitamin GO:0033273 131 0.013
cell morphogenesis GO:0000902 142 0.012
response to acid chemical GO:0001101 222 0.012
organophosphate metabolic process GO:0019637 370 0.012
regulation of catabolic process GO:0009894 113 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
negative regulation of organ growth GO:0046621 3 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
regulation of synapse organization GO:0050807 19 0.012
nucleoside metabolic process GO:0009116 179 0.012
epithelial tube formation GO:0072175 3 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
lipid storage GO:0019915 1 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
negative regulation of signaling GO:0023057 157 0.012
regulation of phosphate metabolic process GO:0019220 349 0.012
autophagic cell death GO:0048102 4 0.012
regulation of synapse structure and activity GO:0050803 21 0.012
neuron neuron synaptic transmission GO:0007270 60 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
receptor mediated endocytosis GO:0006898 42 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
regulation of blood circulation GO:1903522 110 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
neuron development GO:0048666 286 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
positive regulation of molecular function GO:0044093 230 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
cognition GO:0050890 92 0.011
transmembrane transport GO:0055085 412 0.011
cellular homeostasis GO:0019725 252 0.011
cellular ketone metabolic process GO:0042180 51 0.011
olfactory behavior GO:0042048 2 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
neuron projection development GO:0031175 273 0.011
proteolysis GO:0006508 175 0.011
synapse organization GO:0050808 46 0.011
homeostatic process GO:0042592 331 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
single organism intracellular transport GO:1902582 166 0.011
regulation of cellular localization GO:0060341 263 0.011
circulatory system process GO:0003013 183 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
oxoacid metabolic process GO:0043436 290 0.010
regulation of dendritic spine morphogenesis GO:0061001 6 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
actin filament based process GO:0030029 86 0.010
regulation of synaptic transmission GO:0050804 141 0.010
purine containing compound metabolic process GO:0072521 253 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
intracellular signal transduction GO:0035556 314 0.010
Mouse
forebrain generation of neurons GO:0021872 8 0.010
single organism catabolic process GO:0044712 283 0.010
defecation GO:0030421 1 0.010

Mink1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038
central nervous system disease DOID:331 0 0.017
parkinson s disease DOID:14330 0 0.014
synucleinopathy DOID:0050890 0 0.014
neurodegenerative disease DOID:1289 0 0.014