Rattus norvegicus

0 known processes

Gpr44

G protein-coupled receptor 44

Gpr44 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
chemical homeostasis GO:0048878 292 0.123
reproduction GO:0000003 245 0.116
cation transport GO:0006812 382 0.114
regulation of rna biosynthetic process GO:2001141 381 0.106
homeostatic process GO:0042592 331 0.101
regulation of cell proliferation GO:0042127 359 0.098
response to peptide hormone GO:0043434 278 0.095
defense response GO:0006952 194 0.092
anion transport GO:0006820 178 0.090
macromolecular complex subunit organization GO:0043933 339 0.088
cellular response to endogenous stimulus GO:0071495 377 0.087
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.085
regulation of immune system process GO:0002682 123 0.084
apoptotic process GO:0006915 381 0.074
cytosolic calcium ion homeostasis GO:0051480 140 0.074
regulation of apoptotic process GO:0042981 335 0.073
cellular response to oxygen containing compound GO:1901701 386 0.072
neuron differentiation GO:0030182 368 0.071
phasic smooth muscle contraction GO:0014821 3 0.070
programmed cell death GO:0012501 392 0.069
organic acid transport GO:0015849 116 0.067
regulation of hormone levels GO:0010817 187 0.065
response to biotic stimulus GO:0009607 226 0.064
single organism reproductive process GO:0044702 297 0.063
positive regulation of response to stimulus GO:0048584 285 0.063
regulation of multicellular organismal development GO:2000026 376 0.062
response to external biotic stimulus GO:0043207 221 0.061
response to inorganic substance GO:0010035 377 0.060
ovulation cycle GO:0042698 67 0.060
response to carbohydrate GO:0009743 183 0.058
cellular response to lipid GO:0071396 201 0.057
intracellular signal transduction GO:0035556 314 0.057
response to ketone GO:1901654 182 0.056
regulation of transcription dna templated GO:0006355 374 0.056
regulation of programmed cell death GO:0043067 341 0.056
response to insulin GO:0032868 133 0.055
regulation of phosphorus metabolic process GO:0051174 349 0.055
divalent inorganic cation homeostasis GO:0072507 165 0.055
cellular response to acid chemical GO:0071229 75 0.052
calcium ion homeostasis GO:0055074 162 0.052
immune system process GO:0002376 204 0.050
carboxylic acid transport GO:0046942 115 0.050
response to oxygen levels GO:0070482 265 0.050
response to acid chemical GO:0001101 222 0.050
cellular response to hormone stimulus GO:0032870 247 0.050
aging GO:0007568 241 0.050
cell cell signaling GO:0007267 335 0.049
regulation of cellular localization GO:0060341 263 0.049
response to ethanol GO:0045471 162 0.048
reproductive process GO:0022414 372 0.048
protein phosphorylation GO:0006468 345 0.048
anatomical structure morphogenesis GO:0009653 298 0.048
organophosphate metabolic process GO:0019637 370 0.047
regulation of cell differentiation GO:0045595 320 0.047
cation homeostasis GO:0055080 195 0.047
regulation of nucleic acid templated transcription GO:1903506 380 0.047
response to other organism GO:0051707 220 0.047
cellular divalent inorganic cation homeostasis GO:0072503 162 0.046
protein complex subunit organization GO:0071822 302 0.046
regulation of phosphate metabolic process GO:0019220 349 0.045
response to estrogen GO:0043627 232 0.045
positive regulation of transport GO:0051050 245 0.045
cellular response to organonitrogen compound GO:0071417 197 0.045
organ regeneration GO:0031100 101 0.045
carboxylic acid metabolic process GO:0019752 289 0.044
inflammatory response GO:0006954 150 0.044
central nervous system development GO:0007417 311 0.043
lipid metabolic process GO:0006629 283 0.043
regulation of cell development GO:0060284 263 0.042
secretion GO:0046903 307 0.042
cellular chemical homeostasis GO:0055082 247 0.041
cellular calcium ion homeostasis GO:0006874 160 0.041
secretion by cell GO:0032940 248 0.041
single organism behavior GO:0044708 130 0.040
neurological system process GO:0050877 219 0.040
protein complex assembly GO:0006461 263 0.040
cellular response to insulin stimulus GO:0032869 81 0.040
sexual reproduction GO:0019953 148 0.040
organic anion transport GO:0015711 132 0.039
cellular component assembly GO:0022607 360 0.039
positive regulation of signaling GO:0023056 270 0.039
organelle organization GO:0006996 266 0.039
rna metabolic process GO:0016070 406 0.038
ion transmembrane transport GO:0034220 365 0.038
negative regulation of cell death GO:0060548 229 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
negative regulation of transport GO:0051051 136 0.036
positive regulation of phosphorus metabolic process GO:0010562 262 0.036
positive regulation of cell motility GO:2000147 97 0.035
cellular response to nitrogen compound GO:1901699 210 0.035
protein complex biogenesis GO:0070271 263 0.035
cellular metal ion homeostasis GO:0006875 172 0.035
macromolecular complex assembly GO:0065003 273 0.035
response to radiation GO:0009314 137 0.035
cellular component biogenesis GO:0044085 368 0.034
cell projection organization GO:0030030 302 0.034
positive regulation of cell proliferation GO:0008284 249 0.034
multicellular organism reproduction GO:0032504 233 0.034
response to hexose GO:0009746 144 0.034
amide transport GO:0042886 105 0.034
signal release GO:0023061 145 0.034
positive regulation of locomotion GO:0040017 102 0.033
negative regulation of developmental process GO:0051093 125 0.033
response to monosaccharide GO:0034284 159 0.033
leukocyte activation GO:0045321 76 0.033
response to nutrient levels GO:0031667 370 0.033
multi organism reproductive process GO:0044703 262 0.033
positive regulation of cell communication GO:0010647 271 0.033
cellular lipid metabolic process GO:0044255 208 0.033
cellular homeostasis GO:0019725 252 0.033
multicellular organismal reproductive process GO:0048609 233 0.033
nucleic acid templated transcription GO:0097659 379 0.032
positive regulation of molecular function GO:0044093 230 0.032
sensory perception GO:0007600 101 0.032
rna biosynthetic process GO:0032774 380 0.032
response to peptide GO:1901652 292 0.032
regulation of rna metabolic process GO:0051252 391 0.032
g protein coupled receptor signaling pathway GO:0007186 242 0.032
regulation of cell motility GO:2000145 131 0.032
response to metal ion GO:0010038 253 0.031
regulation of catalytic activity GO:0050790 304 0.031
positive regulation of programmed cell death GO:0043068 157 0.031
regulation of locomotion GO:0040012 148 0.030
single organism organelle organization GO:1902589 180 0.030
regulation of phosphorylation GO:0042325 248 0.030
negative regulation of cell communication GO:0010648 158 0.030
protein oligomerization GO:0051259 191 0.030
positive regulation of cellular component organization GO:0051130 200 0.030
metal ion homeostasis GO:0055065 186 0.029
vesicle mediated transport GO:0016192 181 0.029
positive regulation of neurogenesis GO:0050769 165 0.029
peptide hormone secretion GO:0030072 84 0.028
cellular response to growth factor stimulus GO:0071363 162 0.028
positive regulation of protein metabolic process GO:0051247 178 0.028
ion homeostasis GO:0050801 212 0.028
smooth muscle cell proliferation GO:0048659 77 0.028
positive regulation of cell differentiation GO:0045597 217 0.028
regulation of molecular function GO:0065009 398 0.028
regulation of saliva secretion GO:0046877 3 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
negative regulation of multicellular organismal process GO:0051241 203 0.028
positive regulation of cell development GO:0010720 176 0.028
negative regulation of signaling GO:0023057 157 0.028
metal ion transport GO:0030001 289 0.027
regulation of smooth muscle cell proliferation GO:0048660 75 0.027
neuron projection development GO:0031175 273 0.027
locomotion GO:0040011 237 0.027
positive regulation of cell death GO:0010942 184 0.027
acid secretion GO:0046717 48 0.027
macromolecule localization GO:0033036 252 0.027
cognition GO:0050890 92 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
response to extracellular stimulus GO:0009991 380 0.026
amine metabolic process GO:0009308 38 0.025
learning or memory GO:0007611 90 0.025
positive regulation of developmental process GO:0051094 283 0.025
cellular ion homeostasis GO:0006873 184 0.025
negative regulation of cell proliferation GO:0008285 119 0.025
tube development GO:0035295 89 0.025
hormone transport GO:0009914 121 0.025
regulation of epithelial cell proliferation GO:0050678 49 0.025
nitrogen compound transport GO:0071705 229 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
positive regulation of cell migration GO:0030335 96 0.025
neuron development GO:0048666 286 0.024
response to estradiol GO:0032355 164 0.024
saliva secretion GO:0046541 3 0.024
negative regulation of programmed cell death GO:0043069 183 0.024
organic acid metabolic process GO:0006082 292 0.024
regulation of neuron differentiation GO:0045664 208 0.024
regulation of response to wounding GO:1903034 69 0.024
muscle system process GO:0003012 115 0.024
synaptic transmission GO:0007268 235 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.023
response to alkaloid GO:0043279 132 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.023
negative regulation of cellular biosynthetic process GO:0031327 161 0.023
regulation of nervous system development GO:0051960 264 0.023
regulation of signal transduction GO:0009966 318 0.023
positive regulation of response to external stimulus GO:0032103 51 0.023
positive regulation of immune system process GO:0002684 90 0.022
immune response GO:0006955 104 0.022
positive regulation of intracellular signal transduction GO:1902533 138 0.022
regulation of protein metabolic process GO:0051246 289 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
blood circulation GO:0008015 183 0.022
negative regulation of metabolic process GO:0009892 331 0.022
regulation of response to stress GO:0080134 126 0.022
positive regulation of nervous system development GO:0051962 178 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
positive regulation of secretion GO:0051047 140 0.021
response to corticosteroid GO:0031960 235 0.021
regulation of defense response GO:0031347 68 0.021
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.021
hormone metabolic process GO:0042445 69 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
response to glucose GO:0009749 136 0.021
transmembrane transport GO:0055085 412 0.021
cellular response to peptide hormone stimulus GO:0071375 120 0.021
enzyme linked receptor protein signaling pathway GO:0007167 116 0.020
regulation of organelle organization GO:0033043 80 0.020
behavior GO:0007610 205 0.020
cellular component morphogenesis GO:0032989 155 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
epithelium development GO:0060429 96 0.020
acute inflammatory response GO:0002526 58 0.020
transcription dna templated GO:0006351 377 0.020
regeneration GO:0031099 163 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
positive regulation of neuron differentiation GO:0045666 126 0.020
regulation of cellular component organization GO:0051128 368 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
neuropeptide signaling pathway GO:0007218 29 0.019
tissue development GO:0009888 252 0.019
cellular cation homeostasis GO:0030003 180 0.019
cell activation GO:0001775 97 0.019
regulation of neurogenesis GO:0050767 247 0.019
response to bacterium GO:0009617 200 0.019
regulation of mapk cascade GO:0043408 116 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
regulation of hormone secretion GO:0046883 106 0.019
negative regulation of secretion by cell GO:1903531 72 0.019
brain development GO:0007420 247 0.019
positive regulation of cellular component movement GO:0051272 102 0.019
negative regulation of hormone secretion GO:0046888 46 0.019
single organism biosynthetic process GO:0044711 342 0.018
cell motility GO:0048870 202 0.018
muscle cell proliferation GO:0033002 84 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
synaptic transmission gabaergic GO:0051932 22 0.018
tongue morphogenesis GO:0043587 3 0.018
regulation of peptide hormone secretion GO:0090276 80 0.018
cellular amine metabolic process GO:0044106 38 0.018
positive regulation of saliva secretion GO:0046878 3 0.018
regulation of peptide transport GO:0090087 87 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
peptide secretion GO:0002790 86 0.018
aromatic compound catabolic process GO:0019439 168 0.018
cell migration GO:0016477 197 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
brain renin angiotensin system GO:0002035 3 0.017
oxoacid metabolic process GO:0043436 290 0.017
response to nutrient GO:0007584 248 0.017
regulation of peptide secretion GO:0002791 82 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
male sex differentiation GO:0046661 64 0.017
cellular response to peptide GO:1901653 133 0.017
response to nicotine GO:0035094 51 0.017
nucleotide metabolic process GO:0009117 279 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
organ morphogenesis GO:0009887 75 0.017
development of primary sexual characteristics GO:0045137 107 0.016
hormone secretion GO:0046879 115 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
calcium ion transport GO:0006816 131 0.016
heart morphogenesis GO:0003007 3 0.016
urinary bladder smooth muscle contraction GO:0014832 4 0.016
regulation of inflammatory response GO:0050727 48 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
regulation of kinase activity GO:0043549 117 0.016
response to cytokine GO:0034097 215 0.016
regulation of amine transport GO:0051952 54 0.016
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.016
regulation of cell activation GO:0050865 50 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
response to ammonium ion GO:0060359 71 0.016
regulation of neuron projection development GO:0010975 161 0.016
anion transmembrane transport GO:0098656 77 0.016
response to lipopolysaccharide GO:0032496 191 0.016
regulation of protein modification process GO:0031399 194 0.015
regulation of anatomical structure size GO:0090066 135 0.015
regulation of ion transport GO:0043269 245 0.015
proteolysis GO:0006508 175 0.015
glial cell differentiation GO:0010001 65 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
organic substance catabolic process GO:1901575 316 0.015
positive regulation of hormone secretion GO:0046887 65 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
localization of cell GO:0051674 202 0.015
response to progesterone GO:0032570 48 0.015
regulation of establishment of planar polarity GO:0090175 2 0.015
urogenital system development GO:0001655 78 0.015
learning GO:0007612 33 0.015
response to wounding GO:0009611 254 0.015
head development GO:0060322 247 0.014
positive regulation of signal transduction GO:0009967 175 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.014
response to growth factor GO:0070848 189 0.014
copulation GO:0007620 17 0.014
purine containing compound metabolic process GO:0072521 253 0.014
regulation of anion transport GO:0044070 43 0.014
developmental process involved in reproduction GO:0003006 159 0.014
cellular response to external stimulus GO:0071496 118 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
rhythmic process GO:0048511 156 0.014
regulation of chemotaxis GO:0050920 29 0.014
negative regulation of innate immune response GO:0045824 4 0.014
multicellular organism growth GO:0035264 1 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
cellular ketone metabolic process GO:0042180 51 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
cellular response to steroid hormone stimulus GO:0071383 93 0.013
regulation of blood pressure GO:0008217 83 0.013
circulatory system development GO:0072359 134 0.013
positive regulation of epithelial cell proliferation GO:0050679 32 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
regulation of cell migration GO:0030334 128 0.013
gland development GO:0048732 155 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
regulation of amino acid transport GO:0051955 25 0.013
regulation of homeostatic process GO:0032844 101 0.013
regulation of tube size GO:0035150 89 0.013
regulation of membrane potential GO:0042391 110 0.013
response to toxic substance GO:0009636 133 0.013
regulation of insulin secretion GO:0050796 65 0.013
phospholipid metabolic process GO:0006644 61 0.013
regulation of response to external stimulus GO:0032101 106 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
urinary tract smooth muscle contraction GO:0014848 4 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
spermatogenesis GO:0007283 99 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
intestinal absorption GO:0050892 3 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
epithelial cell proliferation GO:0050673 54 0.012
response to mechanical stimulus GO:0009612 134 0.012
cellular response to stress GO:0033554 269 0.012
salivary gland development GO:0007431 3 0.012
positive regulation of defense response GO:0031349 37 0.012
regulation of ossification GO:0030278 32 0.012
cellular hormone metabolic process GO:0034754 49 0.012
actin filament based process GO:0030029 86 0.012
single organism catabolic process GO:0044712 283 0.012
angiotensin mediated drinking behavior GO:0003051 2 0.012
gonad development GO:0008406 104 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
cytoskeleton organization GO:0007010 111 0.012
regulation of growth GO:0040008 105 0.012
regulation of cell projection organization GO:0031344 175 0.012
peptide transport GO:0015833 97 0.012
negative regulation of gene expression GO:0010629 199 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
regulation of secretion by cell GO:1903530 208 0.012
male gamete generation GO:0048232 99 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
negative regulation of glutamate secretion GO:0014050 9 0.012
neuron neuron synaptic transmission GO:0007270 60 0.012
cardiovascular system development GO:0072358 134 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
regulation of organic acid transport GO:0032890 35 0.012
organelle localization GO:0051640 55 0.012
response to fatty acid GO:0070542 65 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
positive regulation of peptide secretion GO:0002793 52 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
muscle structure development GO:0061061 87 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
secretion by tissue GO:0032941 37 0.011
growth GO:0040007 165 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
response to camp GO:0051591 91 0.011
lipid transport GO:0006869 61 0.011
catabolic process GO:0009056 351 0.011
positive regulation of somatostatin secretion GO:0090274 4 0.011
regulation of transferase activity GO:0051338 123 0.011
negative regulation of ion transport GO:0043271 51 0.011
ossification GO:0001503 70 0.011
amino acid transport GO:0006865 70 0.011
regulation of muscle system process GO:0090257 79 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
reproductive system development GO:0061458 128 0.011
regulation of immune response GO:0050776 55 0.011
response to osmotic stress GO:0006970 42 0.011
response to hypoxia GO:0001666 231 0.011
hormone biosynthetic process GO:0042446 25 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
response to organophosphorus GO:0046683 102 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
isoprenoid metabolic process GO:0006720 45 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
positive regulation of peptide hormone secretion GO:0090277 50 0.010
generation of ovulation cycle rhythm GO:0060112 2 0.010
response to vitamin GO:0033273 131 0.010
single organism intracellular transport GO:1902582 166 0.010
response to glucocorticoid GO:0051384 223 0.010
mapk cascade GO:0000165 140 0.010
regulation of secretion GO:0051046 224 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
cell morphogenesis GO:0000902 142 0.010
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
regulation of cellular component movement GO:0051270 150 0.010
lipid localization GO:0010876 62 0.010
regulation of blood vessel size GO:0050880 89 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
dendrite development GO:0016358 72 0.010
carbohydrate homeostasis GO:0033500 75 0.010
positive regulation of transcription dna templated GO:0045893 197 0.010

Gpr44 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014