Rattus norvegicus

15 known processes

Insig2

insulin induced gene 2

Insig2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.103
carboxylic acid metabolic process GO:0019752 289 0.081
programmed cell death GO:0012501 392 0.074
alpha amino acid metabolic process GO:1901605 71 0.064
oxoacid metabolic process GO:0043436 290 0.062
protein complex assembly GO:0006461 263 0.050
organelle organization GO:0006996 266 0.048
cellular catabolic process GO:0044248 295 0.045
cell projection organization GO:0030030 302 0.040
cellular amino acid metabolic process GO:0006520 107 0.039
regulation of molecular function GO:0065009 398 0.039
nucleobase containing small molecule metabolic process GO:0055086 316 0.038
macromolecular complex assembly GO:0065003 273 0.037
regulation of programmed cell death GO:0043067 341 0.037
protein oligomerization GO:0051259 191 0.036
catabolic process GO:0009056 351 0.036
apoptotic process GO:0006915 381 0.031
neuron differentiation GO:0030182 368 0.031
neuron projection development GO:0031175 273 0.028
regulation of apoptotic process GO:0042981 335 0.028
purine containing compound metabolic process GO:0072521 253 0.028
neuron development GO:0048666 286 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.027
carbohydrate derivative metabolic process GO:1901135 346 0.027
response to oxygen levels GO:0070482 265 0.027
organic substance catabolic process GO:1901575 316 0.027
purine ribonucleotide metabolic process GO:0009150 227 0.026
homeostatic process GO:0042592 331 0.026
amine metabolic process GO:0009308 38 0.026
purine nucleoside metabolic process GO:0042278 169 0.026
macromolecular complex subunit organization GO:0043933 339 0.025
purine ribonucleoside metabolic process GO:0046128 168 0.025
regulation of cellular component organization GO:0051128 368 0.025
cellular component biogenesis GO:0044085 368 0.025
glycosyl compound metabolic process GO:1901657 182 0.025
macromolecule localization GO:0033036 252 0.025
negative regulation of apoptotic process GO:0043066 181 0.024
cellular response to stress GO:0033554 269 0.024
cellular amine metabolic process GO:0044106 38 0.024
protein complex biogenesis GO:0070271 263 0.024
negative regulation of cellular component organization GO:0051129 83 0.023
nucleoside metabolic process GO:0009116 179 0.023
nitrogen compound transport GO:0071705 229 0.023
single organism catabolic process GO:0044712 283 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
ribose phosphate metabolic process GO:0019693 235 0.022
response to decreased oxygen levels GO:0036293 237 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
response to other organism GO:0051707 220 0.022
regulation of protein metabolic process GO:0051246 289 0.022
response to external biotic stimulus GO:0043207 221 0.022
regulation of cellular localization GO:0060341 263 0.021
positive regulation of molecular function GO:0044093 230 0.021
aging GO:0007568 241 0.021
response to inorganic substance GO:0010035 377 0.021
ribonucleoside metabolic process GO:0009119 174 0.021
secretion by cell GO:0032940 248 0.021
negative regulation of programmed cell death GO:0043069 183 0.020
single organism intracellular transport GO:1902582 166 0.020
single organism organelle organization GO:1902589 180 0.020
regulation of signal transduction GO:0009966 318 0.020
regulation of cell differentiation GO:0045595 320 0.020
intracellular signal transduction GO:0035556 314 0.020
cellular component assembly GO:0022607 360 0.019
ras protein signal transduction GO:0007265 29 0.019
cellular component morphogenesis GO:0032989 155 0.019
positive regulation of developmental process GO:0051094 283 0.019
response to nutrient levels GO:0031667 370 0.019
gtp metabolic process GO:0046039 72 0.019
ion transmembrane transport GO:0034220 365 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
negative regulation of metabolic process GO:0009892 331 0.019
vesicle mediated transport GO:0016192 181 0.019
cell morphogenesis GO:0000902 142 0.018
multi organism reproductive process GO:0044703 262 0.018
purine nucleoside triphosphate metabolic process GO:0009144 141 0.018
negative regulation of cell death GO:0060548 229 0.017
organophosphate metabolic process GO:0019637 370 0.017
protein complex subunit organization GO:0071822 302 0.017
cytoplasmic transport GO:0016482 115 0.017
reproductive process GO:0022414 372 0.017
regulation of neuron differentiation GO:0045664 208 0.017
regulation of phosphorylation GO:0042325 248 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
reproduction GO:0000003 245 0.017
gtp catabolic process GO:0006184 71 0.016
positive regulation of cell communication GO:0010647 271 0.016
transcription dna templated GO:0006351 377 0.016
positive regulation of protein modification process GO:0031401 142 0.016
regulation of proteasomal protein catabolic process GO:0061136 4 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
metal ion transport GO:0030001 289 0.016
single organism membrane organization GO:0044802 74 0.016
muscle system process GO:0003012 115 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
glycosyl compound catabolic process GO:1901658 126 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
secretion GO:0046903 307 0.015
lipid transport GO:0006869 61 0.015
multicellular organism reproduction GO:0032504 233 0.015
response to oxidative stress GO:0006979 186 0.015
oxidation reduction process GO:0055114 304 0.015
regulation of neuron projection development GO:0010975 161 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.015
protein localization GO:0008104 191 0.015
regulation of ion transport GO:0043269 245 0.015
response to hypoxia GO:0001666 231 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
regulation of cell development GO:0060284 263 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
nucleotide metabolic process GO:0009117 279 0.015
single organism reproductive process GO:0044702 297 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
cellular response to oxygen containing compound GO:1901701 386 0.014
Rat
positive regulation of gene expression GO:0010628 244 0.014
membrane organization GO:0061024 94 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
nucleic acid templated transcription GO:0097659 379 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.014
protein homooligomerization GO:0051260 91 0.014
neurological system process GO:0050877 219 0.014
vesicle fusion with golgi apparatus GO:0048280 4 0.014
regulation of catalytic activity GO:0050790 304 0.014
immune system process GO:0002376 204 0.014
response to corticosteroid GO:0031960 235 0.014
transmission of nerve impulse GO:0019226 42 0.014
cellular ketone metabolic process GO:0042180 51 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
nucleoside triphosphate catabolic process GO:0009143 123 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
regulation of transcription dna templated GO:0006355 374 0.013
growth GO:0040007 165 0.013
regulation of membrane potential GO:0042391 110 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
male gamete generation GO:0048232 99 0.013
response to biotic stimulus GO:0009607 226 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
regulation of secretion GO:0051046 224 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
chemical homeostasis GO:0048878 292 0.013
transmembrane transport GO:0055085 412 0.013
spermatogenesis GO:0007283 99 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.012
organophosphate catabolic process GO:0046434 148 0.012
anion transport GO:0006820 178 0.012
multicellular organismal signaling GO:0035637 44 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
response to extracellular stimulus GO:0009991 380 0.012
chromosome segregation GO:0007059 2 0.012
nucleoside catabolic process GO:0009164 126 0.012
rna metabolic process GO:0016070 406 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
regulation of nervous system development GO:0051960 264 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
neuron death GO:0070997 127 0.012
cation transport GO:0006812 382 0.012
response to ethanol GO:0045471 162 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
regulation of system process GO:0044057 208 0.012
regulation of homotypic cell cell adhesion GO:0034110 4 0.012
response to glucocorticoid GO:0051384 223 0.012
endoplasmic reticulum organization GO:0007029 1 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
cell part morphogenesis GO:0032990 123 0.012
lysosomal transport GO:0007041 8 0.012
negative regulation of transport GO:0051051 136 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
positive regulation of neuron projection development GO:0010976 99 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
regulation of transferase activity GO:0051338 123 0.011
cellular macromolecule localization GO:0070727 122 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
response to cytokine GO:0034097 215 0.011
cellular chemical homeostasis GO:0055082 247 0.011
intracellular transport GO:0046907 185 0.011
ion homeostasis GO:0050801 212 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
cell cycle checkpoint GO:0000075 2 0.011
positive regulation of transport GO:0051050 245 0.011
regulation of secretion by cell GO:1903530 208 0.011
organelle inheritance GO:0048308 2 0.011
cell growth GO:0016049 104 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
positive regulation of cell development GO:0010720 176 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
purine containing compound catabolic process GO:0072523 138 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
negative regulation of neuron death GO:1901215 69 0.010
peptidyl amino acid modification GO:0018193 126 0.010
g protein coupled receptor signaling pathway GO:0007186 242 0.010
cellular homeostasis GO:0019725 252 0.010
response to metal ion GO:0010038 253 0.010
heterocycle catabolic process GO:0046700 167 0.010
organic anion transport GO:0015711 132 0.010
small molecule biosynthetic process GO:0044283 124 0.010
endomembrane system organization GO:0010256 48 0.010

Insig2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011