Rattus norvegicus

32 known processes

Insig1

insulin induced gene 1

Insig1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid biosynthetic process GO:0008610 128 0.868
steroid biosynthetic process GO:0006694 48 0.769
single organism biosynthetic process GO:0044711 342 0.691
alcohol biosynthetic process GO:0046165 38 0.645
lipid metabolic process GO:0006629 283 0.543
metanephric tubule development GO:0072170 4 0.522
cholesterol metabolic process GO:0008203 17 0.508
sterol metabolic process GO:0016125 18 0.460
alcohol metabolic process GO:0006066 77 0.409
small molecule biosynthetic process GO:0044283 124 0.325
cellular lipid metabolic process GO:0044255 208 0.304
steroid metabolic process GO:0008202 73 0.293
sterol biosynthetic process GO:0016126 10 0.210
cellular response to follicle stimulating hormone stimulus GO:0071372 13 0.190
cholesterol biosynthetic process GO:0006695 10 0.162
regulation of cholesterol metabolic process GO:0090181 5 0.157
positive regulation of response to stimulus GO:0048584 285 0.150
isoprenoid metabolic process GO:0006720 45 0.150
cellular response to nitrogen compound GO:1901699 210 0.136
head development GO:0060322 247 0.131
response to fatty acid GO:0070542 65 0.131
cellular response to organic cyclic compound GO:0071407 202 0.115
liver development GO:0001889 90 0.089
regulation of muscle organ development GO:0048634 26 0.089
organic hydroxy compound metabolic process GO:1901615 115 0.088
brain development GO:0007420 247 0.085
gonad development GO:0008406 104 0.076
response to amino acid GO:0043200 75 0.074
response to carbohydrate GO:0009743 183 0.074
single organism reproductive process GO:0044702 297 0.074
response to biotic stimulus GO:0009607 226 0.073
cofactor metabolic process GO:0051186 95 0.073
cellular response to peptide hormone stimulus GO:0071375 120 0.072
cellular ketone body metabolic process GO:0046950 4 0.071
response to ketone GO:1901654 182 0.067
response to acid chemical GO:0001101 222 0.063
kidney development GO:0001822 67 0.059
response to ethanol GO:0045471 162 0.059
isoprenoid biosynthetic process GO:0008299 12 0.059
regulation of response to wounding GO:1903034 69 0.058
regulation of cholesterol biosynthetic process GO:0045540 4 0.054
cellular response to fatty acid GO:0071398 29 0.053
tube development GO:0035295 89 0.053
cellular response to oxygen containing compound GO:1901701 386 0.053
response to inorganic substance GO:0010035 377 0.053
cellular response to lipid GO:0071396 201 0.051
regulation of heart growth GO:0060420 12 0.051
response to extracellular stimulus GO:0009991 380 0.050
response to cholesterol GO:0070723 13 0.049
positive regulation of skeletal muscle tissue development GO:0048643 4 0.046
response to temperature stimulus GO:0009266 94 0.046
response to organophosphorus GO:0046683 102 0.046
secretion GO:0046903 307 0.045
response to bacterium GO:0009617 200 0.045
organic hydroxy compound biosynthetic process GO:1901617 51 0.043
response to external biotic stimulus GO:0043207 221 0.041
tissue development GO:0009888 252 0.041
positive regulation of cell growth GO:0030307 44 0.040
regulation of multicellular organismal development GO:2000026 376 0.040
regulation of response to stress GO:0080134 126 0.039
response to other organism GO:0051707 220 0.037
protein complex biogenesis GO:0070271 263 0.037
demethylation GO:0070988 7 0.035
rna metabolic process GO:0016070 406 0.035
response to oxygen levels GO:0070482 265 0.034
positive regulation of muscle organ development GO:0048636 13 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.033
cellular chemical homeostasis GO:0055082 247 0.032
organic anion transport GO:0015711 132 0.032
organophosphate biosynthetic process GO:0090407 143 0.032
cellular response to alcohol GO:0097306 87 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.030
cellular response to organonitrogen compound GO:0071417 197 0.030
organophosphate metabolic process GO:0019637 370 0.030
response to lipopolysaccharide GO:0032496 191 0.030
protein complex assembly GO:0006461 263 0.030
urogenital system development GO:0001655 78 0.029
cellular response to molecule of bacterial origin GO:0071219 56 0.029
cellular ketone metabolic process GO:0042180 51 0.028
response to corticosteroid GO:0031960 235 0.028
response to molecule of bacterial origin GO:0002237 194 0.028
isopentenyl diphosphate metabolic process GO:0046490 3 0.028
regulation of hormone levels GO:0010817 187 0.027
response to glucose GO:0009749 136 0.027
programmed cell death GO:0012501 392 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
response to testosterone GO:0033574 55 0.026
regulation of rna biosynthetic process GO:2001141 381 0.026
regulation of secretion GO:0051046 224 0.026
response to nutrient GO:0007584 248 0.026
positive regulation of cell proliferation GO:0008284 249 0.025
central nervous system development GO:0007417 311 0.025
positive regulation of developmental process GO:0051094 283 0.024
coenzyme metabolic process GO:0006732 86 0.024
regulation of molecular function GO:0065009 398 0.024
reproductive structure development GO:0048608 128 0.024
reproductive process GO:0022414 372 0.024
male mating behavior GO:0060179 3 0.024
multicellular organism reproduction GO:0032504 233 0.023
response to wounding GO:0009611 254 0.023
response to nutrient levels GO:0031667 370 0.023
intracellular signal transduction GO:0035556 314 0.023
negative regulation of cell death GO:0060548 229 0.023
oxidation reduction process GO:0055114 304 0.023
regulation of developmental growth GO:0048638 45 0.023
striated muscle tissue development GO:0014706 58 0.023
amide transport GO:0042886 105 0.022
regulation of apoptotic process GO:0042981 335 0.022
growth GO:0040007 165 0.022
organic acid transport GO:0015849 116 0.022
negative regulation of response to stimulus GO:0048585 155 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
cellular response to glucocorticoid stimulus GO:0071385 68 0.021
negative regulation of cell communication GO:0010648 158 0.021
cellular amine metabolic process GO:0044106 38 0.021
cell type specific apoptotic process GO:0097285 134 0.021
regulation of signal transduction GO:0009966 318 0.021
response to monosaccharide GO:0034284 159 0.021
neuron differentiation GO:0030182 368 0.021
cellular component biogenesis GO:0044085 368 0.020
protein oligomerization GO:0051259 191 0.020
transcription dna templated GO:0006351 377 0.020
regulation of system process GO:0044057 208 0.020
positive regulation of cell communication GO:0010647 271 0.020
reproduction GO:0000003 245 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
response to peptide GO:1901652 292 0.020
regulation of cell differentiation GO:0045595 320 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.020
regulation of cell proliferation GO:0042127 359 0.020
response to sterol GO:0036314 13 0.019
response to peptide hormone GO:0043434 278 0.019
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.019
circulatory system development GO:0072359 134 0.019
response to triglyceride GO:0034014 3 0.019
regulation of cell growth GO:0001558 85 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
response to hexose GO:0009746 144 0.019
regulation of cellular component organization GO:0051128 368 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
response to stilbenoid GO:0035634 1 0.019
regulation of peptide transport GO:0090087 87 0.019
catabolic process GO:0009056 351 0.018
cellular response to cholesterol GO:0071397 9 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
neuron development GO:0048666 286 0.018
sexual reproduction GO:0019953 148 0.018
regulation of neurogenesis GO:0050767 247 0.018
negative regulation of metabolic process GO:0009892 331 0.018
neuron death GO:0070997 127 0.018
amine metabolic process GO:0009308 38 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
nucleic acid templated transcription GO:0097659 379 0.017
protein complex subunit organization GO:0071822 302 0.017
midgut development GO:0007494 13 0.017
cellular component assembly GO:0022607 360 0.017
chemical homeostasis GO:0048878 292 0.017
regulation of cell development GO:0060284 263 0.017
cell cell signaling GO:0007267 335 0.017
organic substance catabolic process GO:1901575 316 0.017
cellular response to stress GO:0033554 269 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
cellular response to peptide GO:1901653 133 0.017
cell projection organization GO:0030030 302 0.017
nitrogen compound transport GO:0071705 229 0.017
cellular amino acid metabolic process GO:0006520 107 0.016
regulation of response to external stimulus GO:0032101 106 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
oxoacid metabolic process GO:0043436 290 0.016
sex differentiation GO:0007548 113 0.016
response to disaccharide GO:0034285 10 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
negative regulation of homeostatic process GO:0032845 47 0.016
transmission of nerve impulse GO:0019226 42 0.016
developmental process involved in reproduction GO:0003006 159 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.015
reproductive system development GO:0061458 128 0.015
organic acid metabolic process GO:0006082 292 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
positive regulation of cell development GO:0010720 176 0.015
response to purine containing compound GO:0014074 126 0.015
neurological system process GO:0050877 219 0.015
hormone transport GO:0009914 121 0.015
response to decreased oxygen levels GO:0036293 237 0.015
cellular catabolic process GO:0044248 295 0.015
single organism catabolic process GO:0044712 283 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
metal ion transport GO:0030001 289 0.015
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.014
regulation of lipid metabolic process GO:0019216 68 0.014
response to starvation GO:0042594 59 0.014
negative regulation of vasodilation GO:0045908 3 0.014
response to lipoprotein particle GO:0055094 8 0.014
negative regulation of signaling GO:0023057 157 0.014
regulation of peptide hormone secretion GO:0090276 80 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
cellular ion homeostasis GO:0006873 184 0.014
apoptotic process GO:0006915 381 0.014
response to oxidative stress GO:0006979 186 0.014
mapk cascade GO:0000165 140 0.014
positive regulation of cell death GO:0010942 184 0.014
multicellular organismal reproductive process GO:0048609 233 0.013
cellular homeostasis GO:0019725 252 0.013
neuron projection development GO:0031175 273 0.013
blood circulation GO:0008015 183 0.013
cellular response to carbohydrate stimulus GO:0071322 72 0.013
muscle system process GO:0003012 115 0.013
carboxylic acid transport GO:0046942 115 0.013
connective tissue development GO:0061448 33 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
multi organism reproductive process GO:0044703 262 0.013
cation transmembrane transport GO:0098655 263 0.013
secretion by cell GO:0032940 248 0.013
acetyl coa metabolic process GO:0006084 17 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
regulation of phosphorylation GO:0042325 248 0.013
hormone secretion GO:0046879 115 0.013
negative regulation of transport GO:0051051 136 0.013
protein phosphorylation GO:0006468 345 0.013
fatty acid metabolic process GO:0006631 99 0.013
regulation of cell projection organization GO:0031344 175 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
regulation of cellular localization GO:0060341 263 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
regulation of programmed cell death GO:0043067 341 0.013
positive regulation of signaling GO:0023056 270 0.013
response to vitamin e GO:0033197 24 0.013
inorganic ion transmembrane transport GO:0098660 229 0.012
synaptic transmission GO:0007268 235 0.012
male gamete generation GO:0048232 99 0.012
renal system development GO:0072001 67 0.012
terpenoid metabolic process GO:0006721 37 0.012
ketone body metabolic process GO:1902224 3 0.012
regulation of lipid biosynthetic process GO:0046890 38 0.012
ion transmembrane transport GO:0034220 365 0.012
heart morphogenesis GO:0003007 3 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
regulation of peptide secretion GO:0002791 82 0.012
peptide secretion GO:0002790 86 0.012
signal release GO:0023061 145 0.012
regulation of protein metabolic process GO:0051246 289 0.012
spermatogenesis GO:0007283 99 0.012
positive regulation of cardiac muscle cell apoptotic process GO:0010666 3 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
regulation of neuron projection development GO:0010975 161 0.011
response to hypoxia GO:0001666 231 0.011
metanephric nephron tubule development GO:0072234 3 0.011
multicellular organismal signaling GO:0035637 44 0.011
ras protein signal transduction GO:0007265 29 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
circulatory system process GO:0003013 183 0.011
hepaticobiliary system development GO:0061008 90 0.011
cardiovascular system development GO:0072358 134 0.011
regulation of secretion by cell GO:1903530 208 0.011
rna biosynthetic process GO:0032774 380 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
positive regulation of nervous system development GO:0051962 178 0.011
positive regulation of protein modification process GO:0031401 142 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
regulation of transcription dna templated GO:0006355 374 0.011
neuron neuron synaptic transmission GO:0007270 60 0.011
response to metal ion GO:0010038 253 0.011
regulation of rna metabolic process GO:0051252 391 0.011
regulation of neuron differentiation GO:0045664 208 0.011
organelle organization GO:0006996 266 0.011
muscle cell apoptotic process GO:0010657 30 0.011
adipose tissue development GO:0060612 6 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
response to alkaloid GO:0043279 132 0.011
neuronal action potential GO:0019228 35 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010
positive regulation of lipid catabolic process GO:0050996 4 0.010
development of primary sexual characteristics GO:0045137 107 0.010
positive regulation of molecular function GO:0044093 230 0.010
anatomical structure morphogenesis GO:0009653 298 0.010
phospholipid biosynthetic process GO:0008654 29 0.010
peptide transport GO:0015833 97 0.010

Insig1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011
musculoskeletal system disease DOID:17 0 0.011
nervous system disease DOID:863 0 0.011
disease of metabolism DOID:0014667 0 0.011