Rattus norvegicus

36 known processes

Kdm5b

lysine (K)-specific demethylase 5B

(Aliases: RGD1565602,Jarid1b)

Kdm5b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rna biosynthetic process GO:2001141 381 0.131
Mouse
transcription dna templated GO:0006351 377 0.130
Mouse
rna metabolic process GO:0016070 406 0.100
Mouse
regulation of transcription dna templated GO:0006355 374 0.098
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.084
rna biosynthetic process GO:0032774 380 0.075
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.075
transcription from rna polymerase ii promoter GO:0006366 252 0.069
regulation of rna metabolic process GO:0051252 391 0.064
Mouse
organic acid metabolic process GO:0006082 292 0.064
negative regulation of macromolecule metabolic process GO:0010605 260 0.059
Mouse
positive regulation of cellular biosynthetic process GO:0031328 295 0.057
regulation of nucleic acid templated transcription GO:1903506 380 0.053
Mouse
brain development GO:0007420 247 0.051
regulation of multicellular organismal development GO:2000026 376 0.049
response to nutrient levels GO:0031667 370 0.048
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.046
positive regulation of gene expression GO:0010628 244 0.045
negative regulation of multicellular organismal process GO:0051241 203 0.045
positive regulation of cell communication GO:0010647 271 0.043
positive regulation of biosynthetic process GO:0009891 319 0.043
positive regulation of transcription dna templated GO:0045893 197 0.042
positive regulation of rna metabolic process GO:0051254 203 0.041
positive regulation of nucleic acid templated transcription GO:1903508 197 0.040
positive regulation of rna biosynthetic process GO:1902680 197 0.039
cellular ketone metabolic process GO:0042180 51 0.039
central nervous system development GO:0007417 311 0.039
oxoacid metabolic process GO:0043436 290 0.038
response to extracellular stimulus GO:0009991 380 0.037
head development GO:0060322 247 0.037
cellular amino acid metabolic process GO:0006520 107 0.037
organophosphate metabolic process GO:0019637 370 0.036
positive regulation of signaling GO:0023056 270 0.035
cell cell signaling GO:0007267 335 0.034
nucleic acid templated transcription GO:0097659 379 0.033
Mouse
carboxylic acid metabolic process GO:0019752 289 0.031
multicellular organism reproduction GO:0032504 233 0.031
Rat
positive regulation of developmental process GO:0051094 283 0.031
negative regulation of metabolic process GO:0009892 331 0.030
Mouse
response to nutrient GO:0007584 248 0.030
cell projection organization GO:0030030 302 0.030
regulation of cell differentiation GO:0045595 320 0.029
blood circulation GO:0008015 183 0.029
regulation of protein metabolic process GO:0051246 289 0.029
positive regulation of nervous system development GO:0051962 178 0.029
cellular component morphogenesis GO:0032989 155 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
negative regulation of gene expression GO:0010629 199 0.028
Mouse
positive regulation of cell differentiation GO:0045597 217 0.028
nucleotide metabolic process GO:0009117 279 0.028
catabolic process GO:0009056 351 0.028
regulation of cell development GO:0060284 263 0.028
regulation of catalytic activity GO:0050790 304 0.028
cellular amine metabolic process GO:0044106 38 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
homeostatic process GO:0042592 331 0.026
positive regulation of neurogenesis GO:0050769 165 0.026
response to inorganic substance GO:0010035 377 0.026
regulation of neurogenesis GO:0050767 247 0.025
regulation of cell motility GO:2000145 131 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
nucleoside phosphate metabolic process GO:0006753 283 0.025
gastrulation GO:0007369 2 0.025
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
cellular component biogenesis GO:0044085 368 0.025
cell morphogenesis GO:0000902 142 0.024
protein phosphorylation GO:0006468 345 0.024
macromolecular complex assembly GO:0065003 273 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
regulation of protein modification process GO:0031399 194 0.024
single organism catabolic process GO:0044712 283 0.024
cellular homeostasis GO:0019725 252 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
anterior posterior pattern specification GO:0009952 1 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
Mouse Rat
multicellular organismal reproductive process GO:0048609 233 0.023
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
protein oligomerization GO:0051259 191 0.022
intracellular transport GO:0046907 185 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
regulation of membrane potential GO:0042391 110 0.022
organelle organization GO:0006996 266 0.022
Mouse Rat
cellular response to endogenous stimulus GO:0071495 377 0.022
neuron projection development GO:0031175 273 0.022
apoptotic process GO:0006915 381 0.021
neuron differentiation GO:0030182 368 0.021
response to oxygen levels GO:0070482 265 0.021
muscle system process GO:0003012 115 0.021
regulation of nervous system development GO:0051960 264 0.021
positive regulation of multicellular organismal process GO:0051240 387 0.021
heterocycle catabolic process GO:0046700 167 0.021
amine metabolic process GO:0009308 38 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
chemical homeostasis GO:0048878 292 0.021
negative regulation of developmental process GO:0051093 125 0.021
positive regulation of cell development GO:0010720 176 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
regulation of phosphorylation GO:0042325 248 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
organic substance catabolic process GO:1901575 316 0.020
tissue development GO:0009888 252 0.020
neural crest cell differentiation GO:0014033 2 0.020
neuromuscular synaptic transmission GO:0007274 2 0.020
regulation of neuron differentiation GO:0045664 208 0.020
positive regulation of cell proliferation GO:0008284 249 0.019
cellular response to lipid GO:0071396 201 0.019
telencephalon development GO:0021537 62 0.019
multi organism reproductive process GO:0044703 262 0.019
Rat
negative regulation of nervous system development GO:0051961 79 0.019
protein complex biogenesis GO:0070271 263 0.019
locomotion GO:0040011 237 0.019
negative regulation of cell differentiation GO:0045596 99 0.019
response to decreased oxygen levels GO:0036293 237 0.019
axis specification GO:0009798 4 0.019
embryonic pattern specification GO:0009880 1 0.019
ribonucleotide metabolic process GO:0009259 231 0.018
regulation of phosphorus metabolic process GO:0051174 349 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
single organism carbohydrate metabolic process GO:0044723 118 0.018
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.018
cellular component assembly GO:0022607 360 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
Mouse
cellular catabolic process GO:0044248 295 0.018
protein homooligomerization GO:0051260 91 0.018
action potential GO:0001508 54 0.018
synaptic transmission GO:0007268 235 0.018
organonitrogen compound catabolic process GO:1901565 179 0.017
reproductive system development GO:0061458 128 0.017
Rat
ribose phosphate metabolic process GO:0019693 235 0.017
reproductive process GO:0022414 372 0.017
Rat
single organism intracellular transport GO:1902582 166 0.017
respiratory system development GO:0060541 45 0.017
neurological system process GO:0050877 219 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
response to carbohydrate GO:0009743 183 0.017
neuronal action potential GO:0019228 35 0.017
carbohydrate metabolic process GO:0005975 130 0.017
embryonic skeletal system development GO:0048706 3 0.017
developmental process involved in reproduction GO:0003006 159 0.017
Rat
cell projection morphogenesis GO:0048858 123 0.017
pallium development GO:0021543 42 0.017
positive regulation of neuron differentiation GO:0045666 126 0.016
cellular response to stress GO:0033554 269 0.016
regulation of anatomical structure size GO:0090066 135 0.016
reproduction GO:0000003 245 0.016
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.016
mesoderm development GO:0007498 2 0.016
localization of cell GO:0051674 202 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
bmp signaling pathway GO:0030509 4 0.016
single organism cellular localization GO:1902580 102 0.015
regulation of hormone levels GO:0010817 187 0.015
gland development GO:0048732 155 0.015
neuron development GO:0048666 286 0.015
sex differentiation GO:0007548 113 0.015
Rat
regulation of protein phosphorylation GO:0001932 183 0.015
response to estrogen GO:0043627 232 0.015
single organism reproductive process GO:0044702 297 0.015
Rat
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
regulation of locomotion GO:0040012 148 0.015
regulation of transferase activity GO:0051338 123 0.015
cell motility GO:0048870 202 0.015
eye morphogenesis GO:0048592 4 0.015
regulation of cell proliferation GO:0042127 359 0.015
endocytosis GO:0006897 84 0.015
circulatory system process GO:0003013 183 0.014
response to hypoxia GO:0001666 231 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
Mouse
glycosyl compound catabolic process GO:1901658 126 0.014
response to external biotic stimulus GO:0043207 221 0.014
regulation of molecular function GO:0065009 398 0.014
protein complex assembly GO:0006461 263 0.014
purine containing compound metabolic process GO:0072521 253 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
formation of primary germ layer GO:0001704 1 0.014
anatomical structure morphogenesis GO:0009653 298 0.014
rhythmic process GO:0048511 156 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
response to acid chemical GO:0001101 222 0.014
regulation of catabolic process GO:0009894 113 0.014
protein heterooligomerization GO:0051291 89 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
regulation of signal transduction GO:0009966 318 0.013
regulation of apoptotic process GO:0042981 335 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
regulation of neuron projection development GO:0010975 161 0.013
peptidyl amino acid modification GO:0018193 126 0.013
nucleoside metabolic process GO:0009116 179 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
Mouse
proteolysis GO:0006508 175 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
single organism biosynthetic process GO:0044711 342 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
regeneration GO:0031099 163 0.013
protein complex subunit organization GO:0071822 302 0.013
response to peptide GO:1901652 292 0.013
neural crest cell development GO:0014032 2 0.013
salivary gland development GO:0007431 3 0.013
multicellular organism growth GO:0035264 1 0.013
male sex differentiation GO:0046661 64 0.013
Rat
purine ribonucleoside catabolic process GO:0046130 124 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
response to mechanical stimulus GO:0009612 134 0.012
reproductive structure development GO:0048608 128 0.012
Rat
vesicle mediated transport GO:0016192 181 0.012
aromatic compound catabolic process GO:0019439 168 0.012
circulatory system development GO:0072359 134 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
cellular lipid metabolic process GO:0044255 208 0.012
circadian regulation of gene expression GO:0032922 3 0.012
lipid metabolic process GO:0006629 283 0.012
regulation of programmed cell death GO:0043067 341 0.012
transmission of nerve impulse GO:0019226 42 0.012
cellular ion homeostasis GO:0006873 184 0.012
growth GO:0040007 165 0.012
purine nucleoside monophosphate catabolic process GO:0009128 55 0.012
positive regulation of signal transduction GO:0009967 175 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
alternative mrna splicing via spliceosome GO:0000380 4 0.012
nucleoside monophosphate metabolic process GO:0009123 93 0.012
response to monosaccharide GO:0034284 159 0.012
tube development GO:0035295 89 0.012
regulation of system process GO:0044057 208 0.012
neuron projection morphogenesis GO:0048812 122 0.012
regulation of muscle system process GO:0090257 79 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
metal ion homeostasis GO:0055065 186 0.012
multicellular organismal signaling GO:0035637 44 0.012
positive regulation of catabolic process GO:0009896 78 0.012
cellular component movement GO:0006928 248 0.012
protein deubiquitination GO:0016579 4 0.011
ras protein signal transduction GO:0007265 29 0.011
programmed cell death GO:0012501 392 0.011
atp catabolic process GO:0006200 54 0.011
aging GO:0007568 241 0.011
behavior GO:0007610 205 0.011
positive regulation of molecular function GO:0044093 230 0.011
organophosphate catabolic process GO:0046434 148 0.011
sexual reproduction GO:0019953 148 0.011
Rat
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
spermatogenesis GO:0007283 99 0.011
Rat
nucleoside phosphate catabolic process GO:1901292 140 0.011
nucleotide catabolic process GO:0009166 139 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
male gamete generation GO:0048232 99 0.011
Rat
protein autophosphorylation GO:0046777 66 0.011
atp metabolic process GO:0046034 72 0.011
response to vitamin GO:0033273 131 0.011
regulation of cellular component organization GO:0051128 368 0.011
dna metabolic process GO:0006259 96 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
cation transport GO:0006812 382 0.011
negative regulation of protein phosphorylation GO:0001933 44 0.011
regulation of phosphate metabolic process GO:0019220 349 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
limbic system development GO:0021761 38 0.011
sequestering of calcium ion GO:0051208 8 0.011
appendage morphogenesis GO:0035107 4 0.011
response to metal ion GO:0010038 253 0.011
heart morphogenesis GO:0003007 3 0.010
protein catabolic process GO:0030163 30 0.010
regulation of dendrite development GO:0050773 59 0.010
negative regulation of cell development GO:0010721 82 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
cellular response to acid chemical GO:0071229 75 0.010
steroid metabolic process GO:0008202 73 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
Mouse
axon cargo transport GO:0008088 1 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
carboxylic acid biosynthetic process GO:0046394 83 0.010
single organism organelle organization GO:1902589 180 0.010
Mouse Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
Mouse
response to retinoic acid GO:0032526 63 0.010
regulation of cellular component movement GO:0051270 150 0.010

Kdm5b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.036
nervous system disease DOID:863 0 0.036
sensory system disease DOID:0050155 0 0.028
eye and adnexa disease DOID:1492 0 0.028
eye disease DOID:5614 0 0.028
retinal disease DOID:5679 0 0.021
cardiovascular system disease DOID:1287 0 0.012