Rattus norvegicus

6 known processes

Ica1

islet cell autoantigen 1

(Aliases: Ica69)

Ica1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organophosphate metabolic process GO:0019637 370 0.088
regulation of protein metabolic process GO:0051246 289 0.062
regulation of signal transduction GO:0009966 318 0.054
intracellular signal transduction GO:0035556 314 0.054
regulation of rna metabolic process GO:0051252 391 0.052
programmed cell death GO:0012501 392 0.050
nucleoside phosphate metabolic process GO:0006753 283 0.048
catabolic process GO:0009056 351 0.048
regulation of catalytic activity GO:0050790 304 0.047
protein phosphorylation GO:0006468 345 0.046
transcription dna templated GO:0006351 377 0.045
regulation of phosphorus metabolic process GO:0051174 349 0.045
carbohydrate derivative metabolic process GO:1901135 346 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
reproductive process GO:0022414 372 0.043
oxoacid metabolic process GO:0043436 290 0.043
rna metabolic process GO:0016070 406 0.041
carboxylic acid metabolic process GO:0019752 289 0.041
organelle organization GO:0006996 266 0.041
apoptotic process GO:0006915 381 0.041
cellular component assembly GO:0022607 360 0.041
regulation of phosphate metabolic process GO:0019220 349 0.041
regulation of transcription dna templated GO:0006355 374 0.039
regulation of rna biosynthetic process GO:2001141 381 0.039
cellular catabolic process GO:0044248 295 0.039
regulation of cell differentiation GO:0045595 320 0.038
regulation of nucleic acid templated transcription GO:1903506 380 0.038
regulation of cellular component organization GO:0051128 368 0.037
regulation of cellular protein metabolic process GO:0032268 267 0.037
nucleobase containing small molecule metabolic process GO:0055086 316 0.036
organic acid metabolic process GO:0006082 292 0.035
macromolecular complex assembly GO:0065003 273 0.034
regulation of molecular function GO:0065009 398 0.034
cellular nitrogen compound catabolic process GO:0044270 163 0.034
cell cell signaling GO:0007267 335 0.034
regulation of nervous system development GO:0051960 264 0.034
organic substance catabolic process GO:1901575 316 0.033
macromolecule localization GO:0033036 252 0.033
cellular component biogenesis GO:0044085 368 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.031
single organism biosynthetic process GO:0044711 342 0.031
regulation of multicellular organismal development GO:2000026 376 0.031
cation transport GO:0006812 382 0.031
positive regulation of molecular function GO:0044093 230 0.031
negative regulation of metabolic process GO:0009892 331 0.031
response to metal ion GO:0010038 253 0.030
organonitrogen compound catabolic process GO:1901565 179 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
response to extracellular stimulus GO:0009991 380 0.030
protein localization GO:0008104 191 0.030
positive regulation of biosynthetic process GO:0009891 319 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
single organism reproductive process GO:0044702 297 0.029
negative regulation of signaling GO:0023057 157 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
regulation of programmed cell death GO:0043067 341 0.029
multi organism reproductive process GO:0044703 262 0.028
regulation of neurogenesis GO:0050767 247 0.028
regulation of protein modification process GO:0031399 194 0.028
reproduction GO:0000003 245 0.028
purine containing compound metabolic process GO:0072521 253 0.028
nucleotide metabolic process GO:0009117 279 0.028
nucleic acid templated transcription GO:0097659 379 0.027
rna biosynthetic process GO:0032774 380 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
cellular amine metabolic process GO:0044106 38 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
response to nutrient levels GO:0031667 370 0.026
negative regulation of cell death GO:0060548 229 0.026
regulation of cell proliferation GO:0042127 359 0.026
response to inorganic substance GO:0010035 377 0.026
regulation of phosphorylation GO:0042325 248 0.026
cell projection organization GO:0030030 302 0.025
transmembrane transport GO:0055085 412 0.025
single organism carbohydrate metabolic process GO:0044723 118 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
regulation of apoptotic process GO:0042981 335 0.025
secretion GO:0046903 307 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
single organism catabolic process GO:0044712 283 0.025
cellular amino acid metabolic process GO:0006520 107 0.024
amine metabolic process GO:0009308 38 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
neuron differentiation GO:0030182 368 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.024
single organism organelle organization GO:1902589 180 0.024
metal ion transport GO:0030001 289 0.024
organophosphate catabolic process GO:0046434 148 0.023
protein complex biogenesis GO:0070271 263 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
transcription from rna polymerase ii promoter GO:0006366 252 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
response to decreased oxygen levels GO:0036293 237 0.023
purine nucleoside metabolic process GO:0042278 169 0.023
carbohydrate metabolic process GO:0005975 130 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
oxidation reduction process GO:0055114 304 0.022
regulation of cellular localization GO:0060341 263 0.022
aromatic compound catabolic process GO:0019439 168 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
homeostatic process GO:0042592 331 0.022
negative regulation of cellular protein metabolic process GO:0032269 106 0.022
positive regulation of gene expression GO:0010628 244 0.022
chemical homeostasis GO:0048878 292 0.022
protein complex subunit organization GO:0071822 302 0.022
response to peptide GO:1901652 292 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
ion homeostasis GO:0050801 212 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
response to oxygen levels GO:0070482 265 0.021
regulation of cell development GO:0060284 263 0.021
negative regulation of programmed cell death GO:0043069 183 0.021
cellular cation homeostasis GO:0030003 180 0.021
negative regulation of gene expression GO:0010629 199 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
protein complex assembly GO:0006461 263 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
regulation of secretion by cell GO:1903530 208 0.021
negative regulation of cell communication GO:0010648 158 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
response to nutrient GO:0007584 248 0.020
neuron projection development GO:0031175 273 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
nucleoside triphosphate metabolic process GO:0009141 144 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
regulation of neuron differentiation GO:0045664 208 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
negative regulation of protein metabolic process GO:0051248 114 0.020
multicellular organism reproduction GO:0032504 233 0.020
response to peptide hormone GO:0043434 278 0.020
secretion by cell GO:0032940 248 0.020
nucleoside phosphate catabolic process GO:1901292 140 0.019
sexual reproduction GO:0019953 148 0.019
anion transport GO:0006820 178 0.019
neuron development GO:0048666 286 0.019
cellular response to stress GO:0033554 269 0.019
positive regulation of developmental process GO:0051094 283 0.019
cellular chemical homeostasis GO:0055082 247 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.019
response to corticosteroid GO:0031960 235 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
cellular lipid metabolic process GO:0044255 208 0.018
cellular homeostasis GO:0019725 252 0.018
regulation of neuron projection development GO:0010975 161 0.018
inorganic cation transmembrane transport GO:0098662 202 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
response to hypoxia GO:0001666 231 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
cell morphogenesis GO:0000902 142 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
regulation of purine nucleotide catabolic process GO:0033121 65 0.018
metal ion homeostasis GO:0055065 186 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
positive regulation of nucleotide metabolic process GO:0045981 91 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
cellular ion homeostasis GO:0006873 184 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
purine ribonucleotide catabolic process GO:0009154 136 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
heart morphogenesis GO:0003007 3 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
lipid metabolic process GO:0006629 283 0.017
cellular ketone metabolic process GO:0042180 51 0.017
growth GO:0040007 165 0.017
response to glucose GO:0009749 136 0.017
purine nucleotide catabolic process GO:0006195 136 0.017
cation transmembrane transport GO:0098655 263 0.017
synaptic transmission GO:0007268 235 0.017
developmental process involved in reproduction GO:0003006 159 0.017
regulation of catabolic process GO:0009894 113 0.017
cell motility GO:0048870 202 0.017
ras protein signal transduction GO:0007265 29 0.016
vesicle mediated transport GO:0016192 181 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
regulation of ion transport GO:0043269 245 0.016
response to oxidative stress GO:0006979 186 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
regulation of hydrolase activity GO:0051336 143 0.016
nucleotide catabolic process GO:0009166 139 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
regulation of cell projection organization GO:0031344 175 0.016
cellular carbohydrate metabolic process GO:0044262 72 0.016
response to ketone GO:1901654 182 0.016
gamete generation GO:0007276 124 0.016
intracellular transport GO:0046907 185 0.016
ribonucleoside catabolic process GO:0042454 126 0.016
cellular component morphogenesis GO:0032989 155 0.016
ion transmembrane transport GO:0034220 365 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
aging GO:0007568 241 0.015
response to glucocorticoid GO:0051384 223 0.015
cellular component movement GO:0006928 248 0.015
positive regulation of transport GO:0051050 245 0.015
response to radiation GO:0009314 137 0.015
cytoskeleton organization GO:0007010 111 0.015
regulation of secretion GO:0051046 224 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
eye morphogenesis GO:0048592 4 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
regulation of nucleotide catabolic process GO:0030811 65 0.015
heterocycle catabolic process GO:0046700 167 0.015
neurological system process GO:0050877 219 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
regulation of hormone levels GO:0010817 187 0.015
negative regulation of developmental process GO:0051093 125 0.015
cellular response to endogenous stimulus GO:0071495 377 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
regulation of anatomical structure size GO:0090066 135 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
response to monosaccharide GO:0034284 159 0.015
rhythmic process GO:0048511 156 0.014
behavior GO:0007610 205 0.014
cation homeostasis GO:0055080 195 0.014
positive regulation of cell death GO:0010942 184 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
protein transport GO:0015031 132 0.014
negative regulation of phosphate metabolic process GO:0045936 80 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
establishment of protein localization GO:0045184 141 0.014
response to bacterium GO:0009617 200 0.014
nucleoside metabolic process GO:0009116 179 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
negative regulation of molecular function GO:0044092 133 0.014
small molecule biosynthetic process GO:0044283 124 0.014
response to hexose GO:0009746 144 0.014
purine containing compound catabolic process GO:0072523 138 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
gland development GO:0048732 155 0.014
locomotion GO:0040011 237 0.014
response to ethanol GO:0045471 162 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
response to estrogen GO:0043627 232 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
peptidyl amino acid modification GO:0018193 126 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
response to carbohydrate GO:0009743 183 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
cellular protein localization GO:0034613 122 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
response to acid chemical GO:0001101 222 0.013
neuron projection morphogenesis GO:0048812 122 0.013
spermatogenesis GO:0007283 99 0.013
calcium ion homeostasis GO:0055074 162 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
regulation of response to stress GO:0080134 126 0.013
positive regulation of nervous system development GO:0051962 178 0.013
circulatory system process GO:0003013 183 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
response to vitamin GO:0033273 131 0.013
dna metabolic process GO:0006259 96 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
response to reactive oxygen species GO:0000302 120 0.013
regulation of nucleoside metabolic process GO:0009118 66 0.012
mapk cascade GO:0000165 140 0.012
response to growth factor GO:0070848 189 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
localization of cell GO:0051674 202 0.012
response to biotic stimulus GO:0009607 226 0.012
cell type specific apoptotic process GO:0097285 134 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
positive regulation of signaling GO:0023056 270 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
divalent metal ion transport GO:0070838 132 0.012
cell cycle GO:0007049 101 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
organic acid transport GO:0015849 116 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
male gamete generation GO:0048232 99 0.012
response to purine containing compound GO:0014074 126 0.012
regulation of transferase activity GO:0051338 123 0.012
proteolysis GO:0006508 175 0.012
nitrogen compound transport GO:0071705 229 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
positive regulation of protein modification process GO:0031401 142 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
response to external biotic stimulus GO:0043207 221 0.012
regulation of transporter activity GO:0032409 50 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
chromosome segregation GO:0007059 2 0.012
regulation of system process GO:0044057 208 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
axis specification GO:0009798 4 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
regulation of synaptic transmission GO:0050804 141 0.012
regulation of organelle organization GO:0033043 80 0.012
tissue development GO:0009888 252 0.011
positive regulation of cell development GO:0010720 176 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
anterior posterior pattern specification GO:0009952 1 0.011
carboxylic acid transport GO:0046942 115 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
single organism cellular localization GO:1902580 102 0.011
cellular macromolecule localization GO:0070727 122 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
regulation of kinase activity GO:0043549 117 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
camera type eye development GO:0043010 48 0.011
regulation of membrane potential GO:0042391 110 0.011
protein oligomerization GO:0051259 191 0.011
positive regulation of cell communication GO:0010647 271 0.011
spindle organization GO:0007051 2 0.011
blood circulation GO:0008015 183 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
central nervous system development GO:0007417 311 0.011
single organism intracellular transport GO:1902582 166 0.011
nucleoside catabolic process GO:0009164 126 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
hormone transport GO:0009914 121 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
divalent inorganic cation transport GO:0072511 134 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
regulation of gtpase activity GO:0043087 57 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
multicellular organism growth GO:0035264 1 0.011
immune system process GO:0002376 204 0.011
response to temperature stimulus GO:0009266 94 0.011
monovalent inorganic cation transport GO:0015672 172 0.010
embryonic pattern specification GO:0009880 1 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
regulation of dendrite development GO:0050773 59 0.010
signal release GO:0023061 145 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
camera type eye morphogenesis GO:0048593 2 0.010
positive regulation of neurogenesis GO:0050769 165 0.010
organic hydroxy compound metabolic process GO:1901615 115 0.010
amide transport GO:0042886 105 0.010
negative regulation of transport GO:0051051 136 0.010
single organism behavior GO:0044708 130 0.010
organic anion transport GO:0015711 132 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
cytoskeleton dependent cytokinesis GO:0061640 2 0.010
gtp catabolic process GO:0006184 71 0.010
regulation of neuron death GO:1901214 115 0.010
response to other organism GO:0051707 220 0.010
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
adult locomotory behavior GO:0008344 4 0.010

Ica1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
disease of metabolism DOID:0014667 0 0.015
central nervous system disease DOID:331 0 0.011