Rattus norvegicus

29 known processes

Rnpep

arginyl aminopeptidase (aminopeptidase B)

Rnpep biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular metabolic process GO:0031324 281 0.087
rna biosynthetic process GO:0032774 380 0.083
regulation of multicellular organismal development GO:2000026 376 0.079
regulation of cellular component organization GO:0051128 368 0.078
organic acid metabolic process GO:0006082 292 0.071
Rat
regulation of transcription dna templated GO:0006355 374 0.068
transcription dna templated GO:0006351 377 0.066
regulation of nucleic acid templated transcription GO:1903506 380 0.064
nucleic acid templated transcription GO:0097659 379 0.063
nucleobase containing small molecule metabolic process GO:0055086 316 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.060
regulation of rna biosynthetic process GO:2001141 381 0.058
cellular component biogenesis GO:0044085 368 0.058
organophosphate metabolic process GO:0019637 370 0.058
lipid metabolic process GO:0006629 283 0.055
Rat
oxoacid metabolic process GO:0043436 290 0.055
Rat
single organism biosynthetic process GO:0044711 342 0.054
cellular amino acid metabolic process GO:0006520 107 0.054
rna metabolic process GO:0016070 406 0.054
organelle organization GO:0006996 266 0.052
nucleoside phosphate metabolic process GO:0006753 283 0.051
carboxylic acid metabolic process GO:0019752 289 0.048
Rat
response to inorganic substance GO:0010035 377 0.047
Rat
regulation of molecular function GO:0065009 398 0.044
cellular component movement GO:0006928 248 0.043
carbohydrate derivative metabolic process GO:1901135 346 0.043
negative regulation of metabolic process GO:0009892 331 0.043
cellular catabolic process GO:0044248 295 0.042
nucleotide metabolic process GO:0009117 279 0.041
macromolecular complex subunit organization GO:0043933 339 0.041
positive regulation of multicellular organismal process GO:0051240 387 0.041
protein complex subunit organization GO:0071822 302 0.040
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.040
regulation of cell development GO:0060284 263 0.039
negative regulation of cellular biosynthetic process GO:0031327 161 0.039
protein phosphorylation GO:0006468 345 0.038
protein localization GO:0008104 191 0.038
regulation of rna metabolic process GO:0051252 391 0.038
programmed cell death GO:0012501 392 0.038
regulation of cell proliferation GO:0042127 359 0.037
regulation of programmed cell death GO:0043067 341 0.037
negative regulation of multicellular organismal process GO:0051241 203 0.037
locomotion GO:0040011 237 0.036
apoptotic process GO:0006915 381 0.036
intracellular signal transduction GO:0035556 314 0.036
cellular component assembly GO:0022607 360 0.036
cell cell signaling GO:0007267 335 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.035
anatomical structure morphogenesis GO:0009653 298 0.035
regulation of cell differentiation GO:0045595 320 0.035
neuron projection morphogenesis GO:0048812 122 0.035
regulation of anatomical structure morphogenesis GO:0022603 141 0.034
regulation of intracellular signal transduction GO:1902531 218 0.034
regulation of apoptotic process GO:0042981 335 0.034
regulation of catalytic activity GO:0050790 304 0.033
neuron differentiation GO:0030182 368 0.033
cell projection organization GO:0030030 302 0.033
protein complex biogenesis GO:0070271 263 0.032
brain development GO:0007420 247 0.032
secretion GO:0046903 307 0.032
response to oxygen levels GO:0070482 265 0.032
negative regulation of nervous system development GO:0051961 79 0.032
regulation of phosphate metabolic process GO:0019220 349 0.031
positive regulation of molecular function GO:0044093 230 0.031
head development GO:0060322 247 0.031
reproductive process GO:0022414 372 0.031
regulation of phosphorus metabolic process GO:0051174 349 0.030
cellular amine metabolic process GO:0044106 38 0.030
response to metal ion GO:0010038 253 0.030
Rat
regulation of nervous system development GO:0051960 264 0.030
cation transport GO:0006812 382 0.030
vesicle mediated transport GO:0016192 181 0.030
response to extracellular stimulus GO:0009991 380 0.029
neuron projection development GO:0031175 273 0.029
transcription from rna polymerase ii promoter GO:0006366 252 0.029
catabolic process GO:0009056 351 0.029
ras protein signal transduction GO:0007265 29 0.029
cellular component morphogenesis GO:0032989 155 0.029
macromolecular complex assembly GO:0065003 273 0.029
neurological system process GO:0050877 219 0.028
organophosphate biosynthetic process GO:0090407 143 0.028
negative regulation of rna metabolic process GO:0051253 123 0.028
single organism organelle organization GO:1902589 180 0.028
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.028
response to nutrient levels GO:0031667 370 0.028
intracellular transport GO:0046907 185 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.027
purine nucleoside triphosphate metabolic process GO:0009144 141 0.027
cellular response to organic cyclic compound GO:0071407 202 0.027
homeostatic process GO:0042592 331 0.027
cellular cation homeostasis GO:0030003 180 0.027
negative regulation of transcription dna templated GO:0045892 116 0.027
chemical homeostasis GO:0048878 292 0.027
cellular ketone metabolic process GO:0042180 51 0.027
cellular response to oxygen containing compound GO:1901701 386 0.026
purine nucleoside triphosphate catabolic process GO:0009146 122 0.026
small gtpase mediated signal transduction GO:0007264 36 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
purine nucleoside metabolic process GO:0042278 169 0.026
cation transmembrane transport GO:0098655 263 0.026
positive regulation of transport GO:0051050 245 0.026
neuron development GO:0048666 286 0.026
macromolecule localization GO:0033036 252 0.026
central nervous system development GO:0007417 311 0.026
cellular response to hormone stimulus GO:0032870 247 0.026
cell morphogenesis GO:0000902 142 0.026
positive regulation of developmental process GO:0051094 283 0.026
regulation of cell morphogenesis GO:0022604 77 0.026
behavior GO:0007610 205 0.025
regulation of neurogenesis GO:0050767 247 0.025
response to decreased oxygen levels GO:0036293 237 0.025
aging GO:0007568 241 0.025
synaptic growth at neuromuscular junction GO:0051124 1 0.025
g protein coupled receptor signaling pathway GO:0007186 242 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
positive regulation of cell death GO:0010942 184 0.025
negative regulation of cell death GO:0060548 229 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
cellular response to stress GO:0033554 269 0.025
organic substance catabolic process GO:1901575 316 0.025
anterior posterior pattern specification GO:0009952 1 0.025
response to nutrient GO:0007584 248 0.025
ion transmembrane transport GO:0034220 365 0.025
cation homeostasis GO:0055080 195 0.024
cellular ion homeostasis GO:0006873 184 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
response to wounding GO:0009611 254 0.024
response to hypoxia GO:0001666 231 0.024
response to acid chemical GO:0001101 222 0.024
negative regulation of gene expression GO:0010629 199 0.024
growth GO:0040007 165 0.024
amine metabolic process GO:0009308 38 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
synaptic transmission GO:0007268 235 0.023
ion homeostasis GO:0050801 212 0.023
negative regulation of developmental process GO:0051093 125 0.023
positive regulation of signaling GO:0023056 270 0.023
negative regulation of biosynthetic process GO:0009890 168 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
single organism cellular localization GO:1902580 102 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
organonitrogen compound biosynthetic process GO:1901566 167 0.023
cellular chemical homeostasis GO:0055082 247 0.023
organic cyclic compound catabolic process GO:1901361 175 0.022
oxidation reduction process GO:0055114 304 0.022
transmembrane transport GO:0055085 412 0.022
cell morphogenesis involved in differentiation GO:0000904 119 0.022
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
regulation of cellular localization GO:0060341 263 0.022
negative regulation of rna biosynthetic process GO:1902679 118 0.022
metal ion transport GO:0030001 289 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.022
cellular macromolecule localization GO:0070727 122 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.022
cell motility GO:0048870 202 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
regulation of protein metabolic process GO:0051246 289 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
carbohydrate metabolic process GO:0005975 130 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
tissue development GO:0009888 252 0.021
inorganic cation transmembrane transport GO:0098662 202 0.021
reproduction GO:0000003 245 0.021
nitrogen compound transport GO:0071705 229 0.021
single organism membrane organization GO:0044802 74 0.021
cellular homeostasis GO:0019725 252 0.021
metal ion homeostasis GO:0055065 186 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
cellular metal ion homeostasis GO:0006875 172 0.021
ribonucleoside metabolic process GO:0009119 174 0.021
regulation of growth GO:0040008 105 0.021
organonitrogen compound catabolic process GO:1901565 179 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
eye morphogenesis GO:0048592 4 0.020
actin filament based process GO:0030029 86 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
response to estradiol GO:0032355 164 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
cardiovascular system development GO:0072358 134 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.020
protein oligomerization GO:0051259 191 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
negative regulation of apoptotic process GO:0043066 181 0.019
cognition GO:0050890 92 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
regulation of catabolic process GO:0009894 113 0.019
regulation of secretion by cell GO:1903530 208 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
protein complex assembly GO:0006461 263 0.019
nucleoside triphosphate catabolic process GO:0009143 123 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
endocytosis GO:0006897 84 0.019
purine containing compound metabolic process GO:0072521 253 0.019
response to peptide hormone GO:0043434 278 0.019
Rat
purine containing compound catabolic process GO:0072523 138 0.019
nucleoside metabolic process GO:0009116 179 0.019
response to corticosteroid GO:0031960 235 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
heart morphogenesis GO:0003007 3 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
Rat
ribonucleoside triphosphate metabolic process GO:0009199 141 0.018
localization of cell GO:0051674 202 0.018
circulatory system development GO:0072359 134 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
regulation of anatomical structure size GO:0090066 135 0.018
ribonucleoside catabolic process GO:0042454 126 0.018
cytoskeleton organization GO:0007010 111 0.018
heterocycle catabolic process GO:0046700 167 0.018
response to ethanol GO:0045471 162 0.018
regulation of cell projection organization GO:0031344 175 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
single organism intracellular transport GO:1902582 166 0.018
regulation of nucleotide metabolic process GO:0006140 117 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
response to insulin GO:0032868 133 0.018
response to peptide GO:1901652 292 0.018
Rat
regulation of phosphorylation GO:0042325 248 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
single organism reproductive process GO:0044702 297 0.018
cellular protein localization GO:0034613 122 0.018
single organism behavior GO:0044708 130 0.018
cell projection morphogenesis GO:0048858 123 0.018
negative regulation of cell development GO:0010721 82 0.018
nucleoside phosphate catabolic process GO:1901292 140 0.018
regulation of rho gtpase activity GO:0032319 17 0.018
regulation of system process GO:0044057 208 0.018
membrane organization GO:0061024 94 0.018
blood circulation GO:0008015 183 0.017
cell migration GO:0016477 197 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
circulatory system process GO:0003013 183 0.017
nucleoside catabolic process GO:0009164 126 0.017
regulation of neuron differentiation GO:0045664 208 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
negative regulation of neuron differentiation GO:0045665 62 0.017
carbohydrate derivative biosynthetic process GO:1901137 124 0.017
tube development GO:0035295 89 0.017
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.017
regulation of proteasomal protein catabolic process GO:0061136 4 0.017
negative regulation of neurogenesis GO:0050768 78 0.017
multi organism reproductive process GO:0044703 262 0.016
regulation of secretion GO:0051046 224 0.016
single organism catabolic process GO:0044712 283 0.016
positive regulation of gene expression GO:0010628 244 0.016
cardiac chamber development GO:0003205 1 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
regulation of neuron projection development GO:0010975 161 0.016
axis specification GO:0009798 4 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
cytokinetic process GO:0032506 1 0.016
multicellular organism reproduction GO:0032504 233 0.016
regulation of hydrolase activity GO:0051336 143 0.016
response to external biotic stimulus GO:0043207 221 0.016
embryonic pattern specification GO:0009880 1 0.016
anion transport GO:0006820 178 0.016
cell part morphogenesis GO:0032990 123 0.015
organic anion transport GO:0015711 132 0.015
gastrulation GO:0007369 2 0.015
regulation of signal transduction GO:0009966 318 0.015
multicellular organism growth GO:0035264 1 0.015
glycosyl compound catabolic process GO:1901658 126 0.015
response to glucocorticoid GO:0051384 223 0.015
lipid biosynthetic process GO:0008610 128 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
gland development GO:0048732 155 0.015
cellular lipid metabolic process GO:0044255 208 0.015
Rat
response to oxidative stress GO:0006979 186 0.015
rho protein signal transduction GO:0007266 11 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
asymmetric protein localization GO:0008105 2 0.015
regulation of cellular component movement GO:0051270 150 0.015
aromatic compound catabolic process GO:0019439 168 0.015
cellular response to lipid GO:0071396 201 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
positive regulation of nucleoside metabolic process GO:0045979 55 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
nucleoside triphosphate metabolic process GO:0009141 144 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.014
cytoskeleton dependent cytokinesis GO:0061640 2 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
establishment of protein localization GO:0045184 141 0.014
amide transport GO:0042886 105 0.014
negative regulation of signaling GO:0023057 157 0.014
regulation of kinase activity GO:0043549 117 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
response to alkaloid GO:0043279 132 0.014
regulation of locomotion GO:0040012 148 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
positive regulation of secretion GO:0051047 140 0.014
developmental growth GO:0048589 100 0.014
sexual reproduction GO:0019953 148 0.014
negative regulation of transport GO:0051051 136 0.014
learning or memory GO:0007611 90 0.014
regulation of organelle organization GO:0033043 80 0.014
ribonucleotide catabolic process GO:0009261 136 0.014
biological adhesion GO:0022610 110 0.014
response to bacterium GO:0009617 200 0.014
secretion by cell GO:0032940 248 0.013
regulation of neuron death GO:1901214 115 0.013
cell type specific apoptotic process GO:0097285 134 0.013
carboxylic acid transport GO:0046942 115 0.013
negative regulation of molecular function GO:0044092 133 0.013
response to toxic substance GO:0009636 133 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
glycerolipid metabolic process GO:0046486 67 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
lymphoid progenitor cell differentiation GO:0002320 2 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
developmental process involved in reproduction GO:0003006 159 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
response to ketone GO:1901654 182 0.013
regulation of hormone levels GO:0010817 187 0.013
protein transport GO:0015031 132 0.013
regulation of ion transport GO:0043269 245 0.013
response to other organism GO:0051707 220 0.013
response to biotic stimulus GO:0009607 226 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.013
gliogenesis GO:0042063 93 0.013
positive regulation of nervous system development GO:0051962 178 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
response to cytokine GO:0034097 215 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
regulation of membrane potential GO:0042391 110 0.012
small molecule biosynthetic process GO:0044283 124 0.012
positive regulation of cell communication GO:0010647 271 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
regulation of blood circulation GO:1903522 110 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
immune system process GO:0002376 204 0.012
b cell differentiation GO:0030183 2 0.012
gtp catabolic process GO:0006184 71 0.012
cell growth GO:0016049 104 0.012
axon development GO:0061564 96 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
response to estrogen GO:0043627 232 0.012
positive regulation of cell development GO:0010720 176 0.012
peptidyl amino acid modification GO:0018193 126 0.012
organophosphate catabolic process GO:0046434 148 0.012
reproductive structure development GO:0048608 128 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
response to vitamin GO:0033273 131 0.012
nucleotide catabolic process GO:0009166 139 0.012
response to growth factor GO:0070848 189 0.012
actin cytoskeleton organization GO:0030036 73 0.012
organic acid transport GO:0015849 116 0.012
double strand break repair GO:0006302 1 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
muscle system process GO:0003012 115 0.012
protein heterooligomerization GO:0051291 89 0.012
lipid storage GO:0019915 1 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
neural crest cell development GO:0014032 2 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
rna localization GO:0006403 4 0.011
salivary gland development GO:0007431 3 0.011
epithelium development GO:0060429 96 0.011
Rat
cellular response to growth factor stimulus GO:0071363 162 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
response to monosaccharide GO:0034284 159 0.011
peptide secretion GO:0002790 86 0.011
tube formation GO:0035148 3 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
eye development GO:0001654 50 0.011
negative regulation of cell communication GO:0010648 158 0.011
male gamete generation GO:0048232 99 0.011
phospholipid metabolic process GO:0006644 61 0.011
regulation of hormone secretion GO:0046883 106 0.011
rhythmic process GO:0048511 156 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
adult locomotory behavior GO:0008344 4 0.011
regulation of cell growth GO:0001558 85 0.011
signal release GO:0023061 145 0.011
regulation of nucleotide catabolic process GO:0030811 65 0.011
spindle organization GO:0007051 2 0.011
maintenance of location GO:0051235 17 0.011
cell adhesion GO:0007155 110 0.011
regeneration GO:0031099 163 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
regulation of cellular component size GO:0032535 51 0.011
regulation of protein modification process GO:0031399 194 0.011
divalent inorganic cation transport GO:0072511 134 0.010
negative regulation of cell proliferation GO:0008285 119 0.010
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
positive regulation of secretion by cell GO:1903532 128 0.010
spermatogenesis GO:0007283 99 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
positive regulation of catabolic process GO:0009896 78 0.010
regulation of transferase activity GO:0051338 123 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
cellular response to external stimulus GO:0071496 118 0.010
vesicle docking involved in exocytosis GO:0006904 4 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
purine nucleoside monophosphate metabolic process GO:0009126 84 0.010

Rnpep disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
musculoskeletal system disease DOID:17 0 0.029
disease of metabolism DOID:0014667 0 0.016
sensory system disease DOID:0050155 0 0.012
disease of cellular proliferation DOID:14566 0 0.011
inherited metabolic disorder DOID:655 0 0.010
central nervous system disease DOID:331 0 0.010
cancer DOID:162 0 0.010