Rattus norvegicus

0 known processes

Eif4enif1

eukaryotic translation initiation factor 4E nuclear import factor 1

(Aliases: RGD1560908)

Eif4enif1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of rna metabolic process GO:0051252 391 0.457
transcription dna templated GO:0006351 377 0.325
rna metabolic process GO:0016070 406 0.297
nucleic acid templated transcription GO:0097659 379 0.258
rna biosynthetic process GO:0032774 380 0.239
regulation of nucleic acid templated transcription GO:1903506 380 0.230
negative regulation of metabolic process GO:0009892 331 0.208
regulation of transcription dna templated GO:0006355 374 0.200
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.185
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.168
transcription from rna polymerase ii promoter GO:0006366 252 0.167
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.167
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.156
negative regulation of biosynthetic process GO:0009890 168 0.149
intracellular signal transduction GO:0035556 314 0.149
negative regulation of gene expression GO:0010629 199 0.139
regulation of rna biosynthetic process GO:2001141 381 0.139
positive regulation of rna biosynthetic process GO:1902680 197 0.139
positive regulation of biosynthetic process GO:0009891 319 0.130
positive regulation of rna metabolic process GO:0051254 203 0.127
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.125
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.122
positive regulation of cellular protein metabolic process GO:0032270 167 0.122
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.105
neuron differentiation GO:0030182 368 0.103
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.100
negative regulation of rna metabolic process GO:0051253 123 0.098
regulation of molecular function GO:0065009 398 0.096
regulation of nervous system development GO:0051960 264 0.094
positive regulation of cellular biosynthetic process GO:0031328 295 0.089
negative regulation of cellular metabolic process GO:0031324 281 0.086
positive regulation of nucleic acid templated transcription GO:1903508 197 0.082
negative regulation of nucleic acid templated transcription GO:1903507 117 0.081
regulation of catalytic activity GO:0050790 304 0.074
positive regulation of neuron projection development GO:0010976 99 0.074
positive regulation of gene expression GO:0010628 244 0.072
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.071
single organism organelle organization GO:1902589 180 0.071
regulation of cellular protein metabolic process GO:0032268 267 0.068
reproductive process GO:0022414 372 0.067
regulation of neurogenesis GO:0050767 247 0.067
bmp signaling pathway GO:0030509 4 0.065
protein phosphorylation GO:0006468 345 0.063
organic acid metabolic process GO:0006082 292 0.062
negative regulation of cellular biosynthetic process GO:0031327 161 0.061
apoptotic process GO:0006915 381 0.061
regulation of cell proliferation GO:0042127 359 0.060
cellular response to endogenous stimulus GO:0071495 377 0.060
regulation of cell development GO:0060284 263 0.060
negative regulation of macromolecule metabolic process GO:0010605 260 0.058
negative regulation of rna biosynthetic process GO:1902679 118 0.058
regulation of neuron differentiation GO:0045664 208 0.056
multi organism reproductive process GO:0044703 262 0.055
neuron projection development GO:0031175 273 0.055
macromolecule localization GO:0033036 252 0.054
cellular ketone metabolic process GO:0042180 51 0.054
regulation of multicellular organismal development GO:2000026 376 0.054
positive regulation of transcription dna templated GO:0045893 197 0.053
positive regulation of transforming growth factor beta3 production GO:0032916 2 0.053
regulation of neuron projection development GO:0010975 161 0.053
protein complex subunit organization GO:0071822 302 0.052
positive regulation of cell differentiation GO:0045597 217 0.052
positive regulation of developmental process GO:0051094 283 0.052
organelle organization GO:0006996 266 0.051
intracellular transport GO:0046907 185 0.049
multicellular organism reproduction GO:0032504 233 0.049
cellular component assembly GO:0022607 360 0.049
regulation of cellular ketone metabolic process GO:0010565 27 0.049
regulation of intracellular signal transduction GO:1902531 218 0.049
regulation of protein localization GO:0032880 81 0.049
regulation of signal transduction GO:0009966 318 0.049
regulation of cellular localization GO:0060341 263 0.048
macromolecular complex subunit organization GO:0043933 339 0.047
regulation of programmed cell death GO:0043067 341 0.047
regulation of phosphate metabolic process GO:0019220 349 0.047
cellular response to stress GO:0033554 269 0.046
single organism reproductive process GO:0044702 297 0.046
regulation of cell differentiation GO:0045595 320 0.046
peptidyl amino acid modification GO:0018193 126 0.045
positive regulation of cell development GO:0010720 176 0.045
neuron development GO:0048666 286 0.045
protein complex assembly GO:0006461 263 0.044
positive regulation of protein metabolic process GO:0051247 178 0.044
anatomical structure morphogenesis GO:0009653 298 0.044
regulation of protein metabolic process GO:0051246 289 0.043
negative regulation of transcription dna templated GO:0045892 116 0.043
regulation of apoptotic process GO:0042981 335 0.043
positive regulation of nervous system development GO:0051962 178 0.043
cellular component biogenesis GO:0044085 368 0.043
histone h3 acetylation GO:0043966 2 0.042
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
protein complex biogenesis GO:0070271 263 0.041
positive regulation of cell death GO:0010942 184 0.041
response to inorganic substance GO:0010035 377 0.040
regulation of phosphorus metabolic process GO:0051174 349 0.039
regulation of cellular amine metabolic process GO:0033238 8 0.039
secretion GO:0046903 307 0.039
response to growth factor GO:0070848 189 0.039
negative regulation of cell communication GO:0010648 158 0.039
cytoskeleton organization GO:0007010 111 0.038
developmental process involved in reproduction GO:0003006 159 0.037
programmed cell death GO:0012501 392 0.037
cellular response to oxygen containing compound GO:1901701 386 0.037
negative regulation of response to stimulus GO:0048585 155 0.037
oxoacid metabolic process GO:0043436 290 0.037
carboxylic acid metabolic process GO:0019752 289 0.037
amine metabolic process GO:0009308 38 0.036
regulation of phosphorylation GO:0042325 248 0.036
macromolecular complex assembly GO:0065003 273 0.035
response to hypoxia GO:0001666 231 0.035
positive regulation of cell communication GO:0010647 271 0.035
negative regulation of apoptotic process GO:0043066 181 0.035
cellular amine metabolic process GO:0044106 38 0.035
response to estrogen GO:0043627 232 0.034
cellular component morphogenesis GO:0032989 155 0.034
positive regulation of neurogenesis GO:0050769 165 0.034
behavior GO:0007610 205 0.034
regulation of mrna splicing via spliceosome GO:0048024 3 0.033
cellular amino acid metabolic process GO:0006520 107 0.033
regulation of cellular component organization GO:0051128 368 0.033
positive regulation of neuron differentiation GO:0045666 126 0.032
nucleocytoplasmic transport GO:0006913 48 0.032
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.032
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:2001269 1 0.032
protein transport GO:0015031 132 0.031
circulatory system development GO:0072359 134 0.031
locomotion GO:0040011 237 0.031
positive regulation of phosphate metabolic process GO:0045937 262 0.030
smad protein complex assembly GO:0007183 1 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.030
cellular response to organonitrogen compound GO:0071417 197 0.030
negative regulation of programmed cell death GO:0043069 183 0.030
lipid metabolic process GO:0006629 283 0.030
reproduction GO:0000003 245 0.030
response to oxygen levels GO:0070482 265 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.029
regulation of cell projection organization GO:0031344 175 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
multicellular organismal reproductive process GO:0048609 233 0.028
negative regulation of cell death GO:0060548 229 0.028
central nervous system development GO:0007417 311 0.028
response to nutrient levels GO:0031667 370 0.028
establishment of protein localization GO:0045184 141 0.028
regulation of protein transport GO:0051223 68 0.028
positive regulation of cell projection organization GO:0031346 111 0.028
anterior posterior pattern specification GO:0009952 1 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
cell cycle GO:0007049 101 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
single organism behavior GO:0044708 130 0.027
response to extracellular stimulus GO:0009991 380 0.027
positive regulation of molecular function GO:0044093 230 0.027
rhythmic process GO:0048511 156 0.027
negative regulation of molecular function GO:0044092 133 0.026
response to decreased oxygen levels GO:0036293 237 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
positive regulation of signaling GO:0023056 270 0.025
tissue development GO:0009888 252 0.025
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.024
alternative mrna splicing via spliceosome GO:0000380 4 0.024
cell projection organization GO:0030030 302 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
gamete generation GO:0007276 124 0.023
single organism cellular localization GO:1902580 102 0.023
gastrulation GO:0007369 2 0.023
ras protein signal transduction GO:0007265 29 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
nuclear transport GO:0051169 49 0.022
cell morphogenesis involved in differentiation GO:0000904 119 0.022
urogenital system development GO:0001655 78 0.022
response to toxic substance GO:0009636 133 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
single organism nuclear import GO:1902593 35 0.022
growth GO:0040007 165 0.022
cell growth GO:0016049 104 0.022
cellular component movement GO:0006928 248 0.022
transforming growth factor beta3 production GO:0032907 2 0.022
single organism intracellular transport GO:1902582 166 0.021
negative regulation of developmental process GO:0051093 125 0.021
cellular protein localization GO:0034613 122 0.021
regulation of transforming growth factor beta3 production GO:0032910 2 0.021
proteolysis GO:0006508 175 0.020
chemical homeostasis GO:0048878 292 0.020
protein localization GO:0008104 191 0.020
positive regulation of biomineral tissue development GO:0070169 4 0.020
homeostatic process GO:0042592 331 0.020
cell cell signaling GO:0007267 335 0.020
cell morphogenesis GO:0000902 142 0.020
negative regulation of signal transduction GO:0009968 83 0.019
axis specification GO:0009798 4 0.019
regulation of hydrolase activity GO:0051336 143 0.019
mapk cascade GO:0000165 140 0.019
cell fate determination GO:0001709 2 0.019
dna metabolic process GO:0006259 96 0.019
negative regulation of cell development GO:0010721 82 0.019
cell migration GO:0016477 197 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
lipid biosynthetic process GO:0008610 128 0.018
regulation of cell cycle GO:0051726 73 0.018
muscle structure development GO:0061061 87 0.018
negative regulation of cell proliferation GO:0008285 119 0.018
positive regulation of signal transduction GO:0009967 175 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
nucleotide metabolic process GO:0009117 279 0.018
regulation of cell morphogenesis GO:0022604 77 0.018
catabolic process GO:0009056 351 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
embryo development GO:0009790 49 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
secretion by cell GO:0032940 248 0.018
positive regulation of protein modification process GO:0031401 142 0.018
negative regulation of signaling GO:0023057 157 0.018
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathway GO:0097296 1 0.018
response to peptide GO:1901652 292 0.018
neuron projection morphogenesis GO:0048812 122 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.017
sex differentiation GO:0007548 113 0.017
response to peptide hormone GO:0043434 278 0.017
sexual reproduction GO:0019953 148 0.017
regulation of secretion GO:0051046 224 0.017
regulation of transferase activity GO:0051338 123 0.017
developmental growth GO:0048589 100 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
regulation of response to stress GO:0080134 126 0.017
cytoplasmic transport GO:0016482 115 0.017
cell part morphogenesis GO:0032990 123 0.017
circadian rhythm GO:0007623 88 0.017
muscle system process GO:0003012 115 0.017
aging GO:0007568 241 0.016
cellular macromolecule localization GO:0070727 122 0.016
intracellular protein transport GO:0006886 79 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
organic substance catabolic process GO:1901575 316 0.016
actin filament based process GO:0030029 86 0.016
embryonic pattern specification GO:0009880 1 0.016
negative regulation of nervous system development GO:0051961 79 0.016
regulation of protein modification process GO:0031399 194 0.016
protein import GO:0017038 37 0.016
protein localization to organelle GO:0033365 57 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.015
regulation of growth GO:0040008 105 0.015
cell projection morphogenesis GO:0048858 123 0.015
protein import into nucleus GO:0006606 35 0.015
cellular protein complex assembly GO:0043623 44 0.015
neurological system process GO:0050877 219 0.015
response to transforming growth factor beta GO:0071559 46 0.015
protein maturation GO:0051604 68 0.015
protein targeting GO:0006605 61 0.015
localization of cell GO:0051674 202 0.015
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
regulation of establishment of protein localization GO:0070201 69 0.015
cellular response to external stimulus GO:0071496 118 0.015
regulation of cell growth GO:0001558 85 0.014
nuclear import GO:0051170 35 0.014
response to estradiol GO:0032355 164 0.014
response to radiation GO:0009314 137 0.014
positive regulation of transport GO:0051050 245 0.014
reproductive structure development GO:0048608 128 0.014
single organism biosynthetic process GO:0044711 342 0.014
cellular macromolecular complex assembly GO:0034622 58 0.014
response to ketone GO:1901654 182 0.014
protein oligomerization GO:0051259 191 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.014
regulation of proteolysis GO:0030162 66 0.014
purine containing compound metabolic process GO:0072521 253 0.014
embryonic axis specification GO:0000578 1 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
dna integrity checkpoint GO:0031570 2 0.014
multicellular organism growth GO:0035264 1 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
positive regulation of cell motility GO:2000147 97 0.013
positive regulation of adherens junction organization GO:1903393 2 0.013
regulation of organelle organization GO:0033043 80 0.013
response to carbohydrate GO:0009743 183 0.013
response to ethanol GO:0045471 162 0.013
cell motility GO:0048870 202 0.013
response to metal ion GO:0010038 253 0.013
cellular catabolic process GO:0044248 295 0.013
cellular lipid metabolic process GO:0044255 208 0.013
positive regulation of protein kinase activity GO:0045860 73 0.013
regulation of secretion by cell GO:1903530 208 0.013
response to cytokine GO:0034097 215 0.013
positive regulation of transferase activity GO:0051347 81 0.013
gonad development GO:0008406 104 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
regulation of bmp signaling pathway GO:0030510 2 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
male sex differentiation GO:0046661 64 0.012
establishment of protein localization to organelle GO:0072594 44 0.012
response to oxidative stress GO:0006979 186 0.012
response to glucocorticoid GO:0051384 223 0.012
positive regulation of focal adhesion assembly GO:0051894 2 0.012
cell cycle checkpoint GO:0000075 2 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
kidney development GO:0001822 67 0.012
activation of cysteine type endopeptidase activity GO:0097202 4 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
lipid storage GO:0019915 1 0.012
dendrite development GO:0016358 72 0.012
cellular response to lipid GO:0071396 201 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
negative regulation of intracellular signal transduction GO:1902532 38 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
spermatogenesis GO:0007283 99 0.012
development of primary sexual characteristics GO:0045137 107 0.012
cation transport GO:0006812 382 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.012
regulation of dendrite development GO:0050773 59 0.012
protein autophosphorylation GO:0046777 66 0.012
dendrite morphogenesis GO:0048813 43 0.012
regulation of anatomical structure size GO:0090066 135 0.012
vesicle mediated transport GO:0016192 181 0.012
actin cytoskeleton organization GO:0030036 73 0.012
response to reactive oxygen species GO:0000302 120 0.012
meiotic cell cycle process GO:1903046 3 0.011
response to vitamin GO:0033273 131 0.011
adult locomotory behavior GO:0008344 4 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
brain development GO:0007420 247 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of intracellular transport GO:0032386 65 0.011
protein localization to nucleus GO:0034504 39 0.011
wound healing GO:0042060 122 0.011
cellular chemical homeostasis GO:0055082 247 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
chemotaxis GO:0006935 66 0.011
cell type specific apoptotic process GO:0097285 134 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
spindle organization GO:0007051 2 0.011
cardiovascular system development GO:0072358 134 0.011
cellular response to oxidative stress GO:0034599 76 0.011
chromosome segregation GO:0007059 2 0.011
regulation of nucleocytoplasmic transport GO:0046822 28 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.011
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 1 0.011
cellular homeostasis GO:0019725 252 0.011
response to corticosteroid GO:0031960 235 0.011
organ formation GO:0048645 3 0.011
signal transduction involved in regulation of gene expression GO:0023019 4 0.011
forebrain development GO:0030900 98 0.011
dephosphorylation GO:0016311 98 0.011
single organism catabolic process GO:0044712 283 0.011
regulation of cytoskeleton organization GO:0051493 49 0.010
regulation of kinase activity GO:0043549 117 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
response to biotic stimulus GO:0009607 226 0.010
protein targeting to nucleus GO:0044744 35 0.010
nitrogen compound transport GO:0071705 229 0.010
muscle cell differentiation GO:0042692 52 0.010
metal ion transport GO:0030001 289 0.010
posttranscriptional regulation of gene expression GO:0010608 37 0.010
head development GO:0060322 247 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
response to starvation GO:0042594 59 0.010
mullerian duct regression GO:0001880 2 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
cellular response to peptide GO:1901653 133 0.010
positive regulation of cell migration GO:0030335 96 0.010
positive regulation of secretion by cell GO:1903532 128 0.010

Eif4enif1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016