Rattus norvegicus

247 known processes

Akt2

v-akt murine thymoma viral oncogene homolog 2

Akt2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.972
vesicle mediated transport GO:0016192 181 0.653
Mouse Rat
cellular response to insulin stimulus GO:0032869 81 0.649
cellular response to endogenous stimulus GO:0071495 377 0.493
anatomical structure morphogenesis GO:0009653 298 0.441
Rat Fly
positive regulation of biosynthetic process GO:0009891 319 0.361
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.353
regulation of mesenchymal cell proliferation GO:0010464 4 0.326
positive regulation of transcription dna templated GO:0045893 197 0.317
cellular response to peptide hormone stimulus GO:0071375 120 0.315
neutral lipid biosynthetic process GO:0046460 7 0.244
mesenchymal cell proliferation GO:0010463 4 0.239
positive regulation of triglyceride metabolic process GO:0090208 4 0.236
macromolecule localization GO:0033036 252 0.233
Human Mouse Rat Fly
cellular response to peptide GO:1901653 133 0.232
triglyceride metabolic process GO:0006641 21 0.227
single organism biosynthetic process GO:0044711 342 0.223
Human Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.219
cellular component assembly GO:0022607 360 0.216
Yeast Rat Fly
response to monosaccharide GO:0034284 159 0.210
Rat
regulation of phosphate metabolic process GO:0019220 349 0.186
carbohydrate derivative metabolic process GO:1901135 346 0.179
Mouse Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.178
olfactory bulb interneuron differentiation GO:0021889 1 0.172
cellular response to organonitrogen compound GO:0071417 197 0.169
response to interleukin 1 GO:0070555 55 0.163
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.160
response to peptide GO:1901652 292 0.157
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.157
positive regulation of gene expression GO:0010628 244 0.153
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.149
Mouse
positive regulation of phosphorus metabolic process GO:0010562 262 0.149
nucleoside metabolic process GO:0009116 179 0.148
Mouse
establishment of protein localization GO:0045184 141 0.148
Mouse Rat
response to bacterium GO:0009617 200 0.147
homeostatic process GO:0042592 331 0.146
purine ribonucleoside metabolic process GO:0046128 168 0.145
Mouse
response to peptide hormone GO:0043434 278 0.144
response to glucocorticoid GO:0051384 223 0.144
Rat
regulation of glycoprotein metabolic process GO:1903018 6 0.143
anion transmembrane transport GO:0098656 77 0.142
Human
reproductive structure development GO:0048608 128 0.142
neutral lipid metabolic process GO:0006638 21 0.141
nucleotide metabolic process GO:0009117 279 0.137
Mouse
single organism intracellular transport GO:1902582 166 0.137
Mouse Rat
aging GO:0007568 241 0.134
Rat Worm
cellular component biogenesis GO:0044085 368 0.132
Yeast Rat Fly
tube development GO:0035295 89 0.132
positive regulation of locomotion GO:0040017 102 0.131
regulation of transcription dna templated GO:0006355 374 0.131
response to corticosteroid GO:0031960 235 0.131
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.130
negative regulation of rna metabolic process GO:0051253 123 0.127
carboxylic acid metabolic process GO:0019752 289 0.124
Human
regulation of phosphorylation GO:0042325 248 0.124
cellular lipid metabolic process GO:0044255 208 0.123
Human
positive regulation of cellular biosynthetic process GO:0031328 295 0.120
multicellular organism growth GO:0035264 1 0.120
Fly
postnatal olfactory bulb interneuron migration GO:0021827 1 0.119
nucleobase containing small molecule metabolic process GO:0055086 316 0.117
Mouse
ribonucleoside metabolic process GO:0009119 174 0.112
Mouse
negative regulation of cell death GO:0060548 229 0.112
protein transport GO:0015031 132 0.111
Mouse Rat
regulation of actin filament based process GO:0032970 42 0.111
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.109
secretion GO:0046903 307 0.108
Rat
regulation of protein metabolic process GO:0051246 289 0.108
cellular response to hormone stimulus GO:0032870 247 0.105
intracellular signal transduction GO:0035556 314 0.104
single organism organelle organization GO:1902589 180 0.104
Yeast Mouse Rat
response to biotic stimulus GO:0009607 226 0.102
single organism catabolic process GO:0044712 283 0.101
Human Yeast Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.100
spindle organization GO:0007051 2 0.100
regulation of protein phosphorylation GO:0001932 183 0.099
regulation of apoptotic process GO:0042981 335 0.099
activation of phospholipase d activity GO:0031584 2 0.098
Rat
ion transmembrane transport GO:0034220 365 0.097
Human Rat
negative regulation of cellular metabolic process GO:0031324 281 0.094
cellular response to stress GO:0033554 269 0.092
Rat Fly
negative regulation of biosynthetic process GO:0009890 168 0.090
Rat
positive regulation of protein metabolic process GO:0051247 178 0.090
multi multicellular organism process GO:0044706 138 0.088
purine ribonucleotide metabolic process GO:0009150 227 0.088
Mouse
regulation of cellular component organization GO:0051128 368 0.086
Yeast Mouse Rat Fly
negative regulation of osteoblast differentiation GO:0045668 2 0.086
lipid transport GO:0006869 61 0.086
Human
ribonucleoside triphosphate catabolic process GO:0009203 122 0.084
Mouse
regulation of proteasomal protein catabolic process GO:0061136 4 0.083
negative regulation of nucleic acid templated transcription GO:1903507 117 0.083
regulation of programmed cell death GO:0043067 341 0.083
positive regulation of lipid biosynthetic process GO:0046889 25 0.082
tissue development GO:0009888 252 0.081
Rat
response to glucose GO:0009749 136 0.081
Rat
cell motility GO:0048870 202 0.081
response to nutrient levels GO:0031667 370 0.081
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.080
anion transport GO:0006820 178 0.080
Human Rat
regulation of multicellular organismal development GO:2000026 376 0.079
Rat Fly
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.079
Rat
cell projection organization GO:0030030 302 0.079
Rat Fly
neuron differentiation GO:0030182 368 0.078
Rat Fly
regulation of cell motility GO:2000145 131 0.078
nucleoside monophosphate metabolic process GO:0009123 93 0.077
mesoderm development GO:0007498 2 0.077
regulation of phosphorus metabolic process GO:0051174 349 0.076
regulation of protein modification process GO:0031399 194 0.075
positive regulation of protein phosphorylation GO:0001934 135 0.074
regulation of intracellular signal transduction GO:1902531 218 0.073
Mouse Rat
response to extracellular stimulus GO:0009991 380 0.072
positive regulation of cell proliferation GO:0008284 249 0.072
Rat
chemical homeostasis GO:0048878 292 0.071
cellular chemical homeostasis GO:0055082 247 0.071
cytosolic calcium ion homeostasis GO:0051480 140 0.069
ribonucleotide catabolic process GO:0009261 136 0.068
Mouse
regulation of smooth muscle cell proliferation GO:0048660 75 0.068
Rat
regeneration GO:0031099 163 0.068
Rat Fly
negative regulation of cellular biosynthetic process GO:0031327 161 0.066
Rat
nucleoside triphosphate catabolic process GO:0009143 123 0.065
Mouse
monosaccharide metabolic process GO:0005996 61 0.064
Human
multi organism reproductive process GO:0044703 262 0.064
Fly
positive regulation of cellular component organization GO:0051130 200 0.063
Mouse Rat Fly
response to mechanical stimulus GO:0009612 134 0.063
Rat
heart contraction GO:0060047 57 0.062
Rat
inorganic ion transmembrane transport GO:0098660 229 0.062
Rat
regulation of rna biosynthetic process GO:2001141 381 0.062
positive regulation of rna metabolic process GO:0051254 203 0.061
nucleoside catabolic process GO:0009164 126 0.061
Mouse
negative regulation of cell communication GO:0010648 158 0.060
Rat Fly
lipid localization GO:0010876 62 0.059
Human Fly
cellular response to nitrogen compound GO:1901699 210 0.059
head development GO:0060322 247 0.059
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.058
Rat
cellular homeostasis GO:0019725 252 0.058
negative regulation of programmed cell death GO:0043069 183 0.058
single organism membrane organization GO:0044802 74 0.057
Mouse
calcium ion homeostasis GO:0055074 162 0.056
organelle assembly GO:0070925 22 0.056
Yeast
response to external biotic stimulus GO:0043207 221 0.055
protein complex assembly GO:0006461 263 0.055
Rat
reproductive process GO:0022414 372 0.054
Fly
cellular response to external stimulus GO:0071496 118 0.054
Rat
regulation of cell proliferation GO:0042127 359 0.053
Rat Fly
neuron development GO:0048666 286 0.053
Rat Fly
transmembrane transport GO:0055085 412 0.053
Human Mouse Rat
cellular response to cytokine stimulus GO:0071345 127 0.052
negative regulation of gene expression GO:0010629 199 0.052
catabolic process GO:0009056 351 0.052
Human Yeast Mouse
regulation of catabolic process GO:0009894 113 0.052
Human Yeast Mouse
regulation of cardiac muscle tissue development GO:0055024 12 0.052
positive regulation of cell migration GO:0030335 96 0.051
response to cytokine GO:0034097 215 0.051
regulation of cell morphogenesis GO:0022604 77 0.050
Fly
transcription dna templated GO:0006351 377 0.050
purine ribonucleotide catabolic process GO:0009154 136 0.049
Mouse
gamete generation GO:0007276 124 0.049
Fly
regulation of cellular amine metabolic process GO:0033238 8 0.048
rna metabolic process GO:0016070 406 0.048
apoptotic process GO:0006915 381 0.048
acylglycerol metabolic process GO:0006639 21 0.048
positive regulation of glycoprotein metabolic process GO:1903020 3 0.047
regulation of triglyceride biosynthetic process GO:0010866 4 0.047
cytoskeleton organization GO:0007010 111 0.046
Yeast Rat
calcium ion transport GO:0006816 131 0.045
organelle organization GO:0006996 266 0.045
Yeast Mouse Rat
cellular response to starvation GO:0009267 27 0.045
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.045
regulation of phospholipase c activity GO:1900274 9 0.045
cellular response to abiotic stimulus GO:0071214 85 0.044
Rat
negative regulation of rna biosynthetic process GO:1902679 118 0.044
regulation of lymphocyte migration GO:2000401 1 0.044
organic substance catabolic process GO:1901575 316 0.044
Human Yeast Mouse
organophosphate metabolic process GO:0019637 370 0.044
Mouse
response to cadmium ion GO:0046686 35 0.043
regulation of rna metabolic process GO:0051252 391 0.043
regulation of phospholipase activity GO:0010517 12 0.043
Rat
response to acid chemical GO:0001101 222 0.042
Rat
phototransduction visible light GO:0007603 2 0.042
macromolecular complex assembly GO:0065003 273 0.041
Yeast Rat
cellular protein localization GO:0034613 122 0.041
Mouse Rat
cerebral cortex tangential migration using cell cell interactions GO:0021823 1 0.041
macromolecular complex subunit organization GO:0043933 339 0.041
Yeast Rat
regulation of ion transport GO:0043269 245 0.040
purine nucleoside triphosphate metabolic process GO:0009144 141 0.040
Mouse
cardiocyte differentiation GO:0035051 22 0.040
regulation of signal transduction GO:0009966 318 0.040
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.040
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.039
Rat Fly
glycerolipid metabolic process GO:0046486 67 0.039
anatomical structure formation involved in morphogenesis GO:0048646 83 0.039
Fly
lipid metabolic process GO:0006629 283 0.039
Human Fly
positive regulation of cell communication GO:0010647 271 0.038
protein complex subunit organization GO:0071822 302 0.038
Yeast Rat
membrane organization GO:0061024 94 0.038
Mouse
response to toxic substance GO:0009636 133 0.038
Rat
positive regulation of isotype switching GO:0045830 1 0.038
neurological system process GO:0050877 219 0.037
Rat
localization of cell GO:0051674 202 0.037
smad protein complex assembly GO:0007183 1 0.037
cardiovascular system development GO:0072358 134 0.036
positive regulation of cellular protein metabolic process GO:0032270 167 0.036
forebrain development GO:0030900 98 0.036
purine containing compound metabolic process GO:0072521 253 0.036
Mouse
formation of primary germ layer GO:0001704 1 0.036
regulation of protein targeting to membrane GO:0090313 3 0.035
Mouse
regulation of lipid metabolic process GO:0019216 68 0.035
Human
response to nutrient GO:0007584 248 0.034
Rat
single organism reproductive process GO:0044702 297 0.034
Fly
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.034
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.034
cellular amine metabolic process GO:0044106 38 0.034
response to growth factor GO:0070848 189 0.034
organic cyclic compound catabolic process GO:1901361 175 0.034
Yeast Mouse
positive regulation of hydrolase activity GO:0051345 86 0.034
Mouse Rat
negative regulation of tyrosine phosphorylation of stat5 protein GO:0042524 1 0.034
regulation of cellular component biogenesis GO:0044087 86 0.034
Rat Fly
response to insulin GO:0032868 133 0.033
behavior GO:0007610 205 0.033
ribonucleotide metabolic process GO:0009259 231 0.033
Mouse
nucleoside triphosphate metabolic process GO:0009141 144 0.033
Mouse
positive regulation of cell development GO:0010720 176 0.033
Fly
locomotion GO:0040011 237 0.033
protein phosphorylation GO:0006468 345 0.033
mesodermal cell differentiation GO:0048333 1 0.033
response to hexose GO:0009746 144 0.032
Rat
aromatic compound catabolic process GO:0019439 168 0.032
Yeast Mouse
olfactory bulb interneuron development GO:0021891 1 0.032
purine nucleotide metabolic process GO:0006163 229 0.032
Mouse
intracellular transport GO:0046907 185 0.032
Mouse Rat
response to purine containing compound GO:0014074 126 0.032
tangential migration from the subventricular zone to the olfactory bulb GO:0022028 1 0.032
positive regulation of cellular component movement GO:0051272 102 0.032
vasculogenesis GO:0001570 3 0.031
female pregnancy GO:0007565 122 0.031
cellular response to organic cyclic compound GO:0071407 202 0.031
divalent inorganic cation transport GO:0072511 134 0.031
organic acid metabolic process GO:0006082 292 0.031
Human
protein localization GO:0008104 191 0.031
Mouse Rat
single organism cellular localization GO:1902580 102 0.031
Mouse Rat
microvillus assembly GO:0030033 2 0.031
cerebral cortex tangential migration GO:0021800 1 0.031
transcription from rna polymerase ii promoter GO:0006366 252 0.030
glycosyl compound metabolic process GO:1901657 182 0.030
Mouse
positive regulation of cell projection organization GO:0031346 111 0.030
Rat Fly
positive regulation of intracellular signal transduction GO:1902533 138 0.030
Rat
response to metal ion GO:0010038 253 0.030
embryonic cranial skeleton morphogenesis GO:0048701 2 0.030
response to inorganic substance GO:0010035 377 0.030
Rat
guanosine containing compound catabolic process GO:1901069 71 0.029
Mouse
cell migration GO:0016477 197 0.029
ribose phosphate metabolic process GO:0019693 235 0.029
Mouse
positive regulation of phosphorylation GO:0042327 177 0.029
central nervous system development GO:0007417 311 0.029
Rat
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.029
Human Mouse Rat Worm Fly
developmental induction GO:0031128 2 0.029
negative regulation of metabolic process GO:0009892 331 0.029
organic hydroxy compound transport GO:0015850 77 0.029
Rat
monocarboxylic acid metabolic process GO:0032787 152 0.029
Human
vesicle fusion GO:0006906 14 0.029
Mouse
negative regulation of developmental process GO:0051093 125 0.028
Fly
purine nucleoside triphosphate catabolic process GO:0009146 122 0.028
Mouse
cellular amino acid metabolic process GO:0006520 107 0.028
hexose metabolic process GO:0019318 58 0.028
Human
cellular cation homeostasis GO:0030003 180 0.028
oxoacid metabolic process GO:0043436 290 0.028
Human
response to vitamin d GO:0033280 34 0.028
Rat
nucleic acid templated transcription GO:0097659 379 0.027
metanephric nephron tubule epithelial cell differentiation GO:0072257 1 0.027
response to other organism GO:0051707 220 0.027
nucleobase containing compound catabolic process GO:0034655 152 0.027
Yeast Mouse
carboxylic acid transport GO:0046942 115 0.027
Human Rat
purine nucleoside monophosphate metabolic process GO:0009126 84 0.027
sterol transport GO:0015918 6 0.027
negative regulation of protein import into nucleus translocation GO:0033159 1 0.027
cellular nitrogen compound catabolic process GO:0044270 163 0.027
Yeast Mouse
macromolecule catabolic process GO:0009057 58 0.027
Yeast
regulation of cell projection organization GO:0031344 175 0.027
Rat Fly
reproductive system development GO:0061458 128 0.027
cellular ion homeostasis GO:0006873 184 0.027
muscle cell proliferation GO:0033002 84 0.026
Rat
organophosphate catabolic process GO:0046434 148 0.026
Mouse
organophosphate biosynthetic process GO:0090407 143 0.026
positive regulation of transport GO:0051050 245 0.026
actin filament bundle assembly GO:0051017 19 0.026
Rat
carbohydrate metabolic process GO:0005975 130 0.026
Human Rat
negative regulation of transcription dna templated GO:0045892 116 0.026
mapk cascade GO:0000165 140 0.026
Rat
limb morphogenesis GO:0035108 4 0.026
insulin like growth factor receptor signaling pathway GO:0048009 3 0.026
cellular response to lipid GO:0071396 201 0.026
regulation of ion transmembrane transport GO:0034765 121 0.026
Human
lipid biosynthetic process GO:0008610 128 0.026
acylglycerol biosynthetic process GO:0046463 7 0.026
autophagy GO:0006914 19 0.025
Yeast
retinoic acid receptor signaling pathway GO:0048384 7 0.025
single organism carbohydrate metabolic process GO:0044723 118 0.025
Human Rat
cation homeostasis GO:0055080 195 0.025
regulation of activation of jak2 kinase activity GO:0010534 1 0.025
anterior posterior pattern specification GO:0009952 1 0.025
divalent metal ion transport GO:0070838 132 0.025
negative regulation of transport GO:0051051 136 0.025
Human
sensory perception GO:0007600 101 0.025
cellular macromolecular complex assembly GO:0034622 58 0.025
Yeast
positive regulation of phospholipase activity GO:0010518 10 0.024
Rat
regulation of cellular component movement GO:0051270 150 0.024
gland development GO:0048732 155 0.024
ion homeostasis GO:0050801 212 0.024
reactive oxygen species biosynthetic process GO:1903409 8 0.024
fatty acid biosynthetic process GO:0006633 33 0.024
positive regulation of signal transduction GO:0009967 175 0.024
jnk cascade GO:0007254 28 0.024
Rat
regulation of body fluid levels GO:0050878 90 0.024
regulation of fatty acid metabolic process GO:0019217 18 0.024
Human
regulation of cellular ketone metabolic process GO:0010565 27 0.023
Human
response to molecule of bacterial origin GO:0002237 194 0.023
positive regulation of protein targeting to membrane GO:0090314 1 0.023
Mouse
mitotic spindle organization GO:0007052 2 0.023
cellular divalent inorganic cation homeostasis GO:0072503 162 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
positive regulation of cell motility GO:2000147 97 0.023
cellular response to acid chemical GO:0071229 75 0.023
response to carbohydrate GO:0009743 183 0.023
Rat
regulation of response to stress GO:0080134 126 0.023
Rat Fly
regulation of anion transport GO:0044070 43 0.023
Human
secretion by cell GO:0032940 248 0.023
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
positive regulation of developmental process GO:0051094 283 0.023
Rat Fly
developmental growth GO:0048589 100 0.023
Rat Fly
protein targeting to membrane GO:0006612 11 0.023
Mouse
positive regulation of signaling GO:0023056 270 0.023
regulation of molecular function GO:0065009 398 0.022
response to organophosphorus GO:0046683 102 0.022
g protein coupled glutamate receptor signaling pathway GO:0007216 8 0.022
cell projection assembly GO:0030031 21 0.022
Rat
metal ion homeostasis GO:0055065 186 0.022
response to lipopolysaccharide GO:0032496 191 0.022
synaptic transmission GO:0007268 235 0.022
Rat Fly
glycerol 3 phosphate metabolic process GO:0006072 2 0.022
somatic recombination of immunoglobulin gene segments GO:0016447 1 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
Fly
regulation of cell differentiation GO:0045595 320 0.022
Fly
regulation of catalytic activity GO:0050790 304 0.022
cellular response to biotic stimulus GO:0071216 59 0.022
lung development GO:0030324 43 0.022
smooth muscle cell proliferation GO:0048659 77 0.022
Rat
cellular component morphogenesis GO:0032989 155 0.022
Rat Fly
regulation of cell migration GO:0030334 128 0.022
protein oligomerization GO:0051259 191 0.021
Rat
intracellular protein transport GO:0006886 79 0.021
Mouse Rat
negative regulation of cell development GO:0010721 82 0.021
brain development GO:0007420 247 0.021
multicellular organismal signaling GO:0035637 44 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
cell cell signaling GO:0007267 335 0.021
Rat Fly
cell adhesion GO:0007155 110 0.021
Rat
protein localization to organelle GO:0033365 57 0.020
Rat
neuron projection development GO:0031175 273 0.020
Rat Fly
pallium development GO:0021543 42 0.020
adp biosynthetic process GO:0006172 8 0.020
negative regulation of activation of jak2 kinase activity GO:1902569 1 0.020
regulation of neuron differentiation GO:0045664 208 0.020
Fly
signal transduction by phosphorylation GO:0023014 144 0.020
Rat
reproduction GO:0000003 245 0.020
Fly
regulation of cell cycle GO:0051726 73 0.020
Rat
regulation of fat cell differentiation GO:0045598 3 0.020
ras protein signal transduction GO:0007265 29 0.019
substrate dependent cerebral cortex tangential migration GO:0021825 1 0.019
muscle cell differentiation GO:0042692 52 0.019
Fly
multicellular organism reproduction GO:0032504 233 0.019
Fly
specification of organ identity GO:0010092 2 0.019
positive regulation of cell death GO:0010942 184 0.019
Rat
response to estrogen GO:0043627 232 0.019
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
regulation of protein kinase activity GO:0045859 105 0.019
Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
Rat Fly
glandular epithelial cell differentiation GO:0002067 4 0.018
programmed cell death GO:0012501 392 0.018
lipid storage GO:0019915 1 0.018
Fly
organic acid transport GO:0015849 116 0.018
Human Rat
detection of visible light GO:0009584 3 0.018
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
negative regulation of nervous system development GO:0051961 79 0.018
Fly
inner ear morphogenesis GO:0042472 1 0.018
protein autophosphorylation GO:0046777 66 0.018
Rat
positive regulation of protein modification process GO:0031401 142 0.018
fatty acid metabolic process GO:0006631 99 0.018
Human
negative regulation of multicellular organismal process GO:0051241 203 0.018
Rat Fly
positive regulation of cell differentiation GO:0045597 217 0.018
Fly
negative regulation of intracellular signal transduction GO:1902532 38 0.018
Rat
sexual reproduction GO:0019953 148 0.018
Fly
regulation of lipid biosynthetic process GO:0046890 38 0.018
microtubule cytoskeleton organization GO:0000226 25 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
Mouse
mesenchymal to epithelial transition GO:0060231 3 0.018
nucleotide catabolic process GO:0009166 139 0.018
Mouse
ribonucleoside monophosphate metabolic process GO:0009161 88 0.018
cell proliferation in forebrain GO:0021846 3 0.017
cation transport GO:0006812 382 0.017
mesoderm morphogenesis GO:0048332 1 0.017
dephosphorylation GO:0016311 98 0.017
response to hypoxia GO:0001666 231 0.017
Rat
triglyceride biosynthetic process GO:0019432 7 0.017
negative regulation of heart growth GO:0061117 3 0.017
golgi vesicle transport GO:0048193 22 0.017
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.017
protein complex biogenesis GO:0070271 263 0.017
Rat
action potential GO:0001508 54 0.017
negative regulation of ion transport GO:0043271 51 0.017
Human
regulation of skeletal muscle tissue regeneration GO:0043416 2 0.017
hematopoietic or lymphoid organ development GO:0048534 36 0.017
activation of protein kinase activity GO:0032147 47 0.017
Rat
lipid oxidation GO:0034440 30 0.017
Human
cranial nerve morphogenesis GO:0021602 1 0.017
glucose metabolic process GO:0006006 52 0.017
Human
rna localization GO:0006403 4 0.017
protein catabolic process GO:0030163 30 0.017
embryonic pattern specification GO:0009880 1 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
sensory perception of pain GO:0019233 73 0.017
response to corticosterone GO:0051412 40 0.017
Rat
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
organic anion transport GO:0015711 132 0.016
Human Rat
regulation of system process GO:0044057 208 0.016
Rat
defense response to gram negative bacterium GO:0050829 3 0.016
telencephalon development GO:0021537 62 0.016
cellular protein complex assembly GO:0043623 44 0.016
cellular ketone metabolic process GO:0042180 51 0.016
Human
muscle system process GO:0003012 115 0.016
Rat
regulation of cellular response to stress GO:0080135 49 0.016
Rat Fly
purine nucleoside catabolic process GO:0006152 124 0.016
Mouse
positive regulation of tolerance induction GO:0002645 1 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
inorganic anion transport GO:0015698 41 0.016
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.016
cytoplasmic transport GO:0016482 115 0.016
Rat
negative regulation of nephron tubule epithelial cell differentiation GO:0072183 1 0.016
acyl coa metabolic process GO:0006637 28 0.016
regulation of response to external stimulus GO:0032101 106 0.016
proteolysis GO:0006508 175 0.016
positive regulation of protein kinase activity GO:0045860 73 0.016
Rat
salivary gland morphogenesis GO:0007435 1 0.016
regulation of mapk cascade GO:0043408 116 0.016
Rat
negative regulation of apoptotic process GO:0043066 181 0.016
regulation of hydrolase activity GO:0051336 143 0.016
negative regulation of signaling GO:0023057 157 0.016
Rat Fly
epithelial cell proliferation GO:0050673 54 0.016
response to estradiol GO:0032355 164 0.016
Rat
regulation of cell development GO:0060284 263 0.015
Fly
cellular carbohydrate metabolic process GO:0044262 72 0.015
Human Rat
positive regulation of monooxygenase activity GO:0032770 5 0.015
morphogenesis of embryonic epithelium GO:0016331 3 0.015
ribonucleotide biosynthetic process GO:0009260 85 0.015
regulation of growth GO:0040008 105 0.015
Rat Fly
ossification GO:0001503 70 0.015
bmp signaling pathway GO:0030509 4 0.015
hematopoietic progenitor cell differentiation GO:0002244 2 0.015
sensory perception of bitter taste GO:0050913 4 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
Rat
regulation of hormone levels GO:0010817 187 0.015
negative regulation of protein modification process GO:0031400 52 0.015
Rat
positive regulation of cellular catabolic process GO:0031331 71 0.015
Human Mouse
negative regulation of hydrogen peroxide metabolic process GO:0010727 2 0.015
biological adhesion GO:0022610 110 0.015
Rat
appendage morphogenesis GO:0035107 4 0.015
cell substrate adhesion GO:0031589 29 0.015
Rat
negative regulation of synaptic transmission GO:0050805 29 0.015
Fly
gastrulation GO:0007369 2 0.015
regulation of organ formation GO:0003156 2 0.015
response to temperature stimulus GO:0009266 94 0.015
Rat
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.015
regulation of organ growth GO:0046620 13 0.015
Fly
negative regulation of cell differentiation GO:0045596 99 0.015
nucleoside phosphate biosynthetic process GO:1901293 102 0.015
monocarboxylic acid biosynthetic process GO:0072330 48 0.015
regulation of neuron projection development GO:0010975 161 0.014
Fly
inorganic cation transmembrane transport GO:0098662 202 0.014
Rat
synaptic growth at neuromuscular junction GO:0051124 1 0.014
Fly
ribonucleoside biosynthetic process GO:0042455 25 0.014
rhythmic process GO:0048511 156 0.014
Fly
regulation of striated muscle tissue development GO:0016202 25 0.014
microvillus organization GO:0032528 2 0.014
circulatory system process GO:0003013 183 0.014
Rat
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 19 0.014
regulation of calcium ion transport GO:0051924 77 0.014
lipid modification GO:0030258 52 0.014
Human
jak stat cascade GO:0007259 26 0.014
response to activity GO:0014823 73 0.014

Akt2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.130
musculoskeletal system disease DOID:17 0 0.130
connective tissue disease DOID:65 0 0.116
disease of metabolism DOID:0014667 0 0.097
Human
carbohydrate metabolic disorder DOID:2978 0 0.097
inherited metabolic disorder DOID:655 0 0.097
bone disease DOID:0080001 0 0.036
bone development disease DOID:0080006 0 0.029
endocrine system disease DOID:28 0 0.016