Rattus norvegicus

108 known processes

Pde3a

phosphodiesterase 3A, cGMP inhibited

(Aliases: RNPDE3A)

Pde3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of secretion GO:0051047 140 0.621
positive regulation of signaling GO:0023056 270 0.555
cell migration GO:0016477 197 0.513
cation transport GO:0006812 382 0.507
regulation of ion transport GO:0043269 245 0.491
regulation of secretion GO:0051046 224 0.473
Rat
regulation of cellular localization GO:0060341 263 0.466
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.460
Mouse
response to molecule of bacterial origin GO:0002237 194 0.441
neurological system process GO:0050877 219 0.395
intracellular signal transduction GO:0035556 314 0.382
Human
cell cell signaling GO:0007267 335 0.369
Rat
response to other organism GO:0051707 220 0.313
protein localization GO:0008104 191 0.296
immune system process GO:0002376 204 0.278
positive regulation of transport GO:0051050 245 0.267
positive regulation of cell communication GO:0010647 271 0.265
regulation of cellular protein metabolic process GO:0032268 267 0.246
reproductive process GO:0022414 372 0.242
cell motility GO:0048870 202 0.228
response to bacterium GO:0009617 200 0.228
sensory perception GO:0007600 101 0.225
positive regulation of secretion by cell GO:1903532 128 0.225
positive regulation of locomotion GO:0040017 102 0.223
negative regulation of response to stimulus GO:0048585 155 0.216
regulation of locomotion GO:0040012 148 0.214
positive regulation of response to stimulus GO:0048584 285 0.207
immune response GO:0006955 104 0.207
positive regulation of nervous system development GO:0051962 178 0.199
response to ethanol GO:0045471 162 0.190
positive regulation of cell motility GO:2000147 97 0.184
signal release GO:0023061 145 0.175
Rat
positive regulation of intracellular signal transduction GO:1902533 138 0.171
lipid biosynthetic process GO:0008610 128 0.170
regulation of molecular function GO:0065009 398 0.169
regulation of synaptic transmission GO:0050804 141 0.169
single organism behavior GO:0044708 130 0.166
cellular response to cytokine stimulus GO:0071345 127 0.165
regulation of nervous system development GO:0051960 264 0.165
regulation of hormone secretion GO:0046883 106 0.165
Rat
secretion by cell GO:0032940 248 0.163
Rat
regulation of metal ion transport GO:0010959 118 0.159
regulation of secretion by cell GO:1903530 208 0.154
Rat
cellular response to endogenous stimulus GO:0071495 377 0.149
Human
reproductive system development GO:0061458 128 0.148
positive regulation of protein metabolic process GO:0051247 178 0.146
cellular component movement GO:0006928 248 0.137
protein phosphorylation GO:0006468 345 0.136
transcription dna templated GO:0006351 377 0.136
response to lipopolysaccharide GO:0032496 191 0.135
synaptic transmission GO:0007268 235 0.135
positive regulation of phosphorylation GO:0042327 177 0.134
reproduction GO:0000003 245 0.134
chemical homeostasis GO:0048878 292 0.133
regulation of exocytosis GO:0017157 37 0.132
regulation of phosphorus metabolic process GO:0051174 349 0.129
muscle contraction GO:0006936 88 0.126
immune effector process GO:0002252 53 0.126
regulation of phosphorylation GO:0042325 248 0.124
organic hydroxy compound metabolic process GO:1901615 115 0.123
response to wounding GO:0009611 254 0.123
regulation of cell differentiation GO:0045595 320 0.121
Mouse
signal transduction by phosphorylation GO:0023014 144 0.120
regulation of rna metabolic process GO:0051252 391 0.120
response to estrogen GO:0043627 232 0.119
neuron development GO:0048666 286 0.116
multicellular organism reproduction GO:0032504 233 0.114
hormone secretion GO:0046879 115 0.111
Rat
positive regulation of phosphorus metabolic process GO:0010562 262 0.111
regulation of protein phosphorylation GO:0001932 183 0.110
regulation of immune system process GO:0002682 123 0.110
positive regulation of cellular protein metabolic process GO:0032270 167 0.109
regulation of hormone levels GO:0010817 187 0.107
Rat
apoptotic process GO:0006915 381 0.106
positive regulation of neurogenesis GO:0050769 165 0.106
regulation of neuron death GO:1901214 115 0.105
regulation of anatomical structure morphogenesis GO:0022603 141 0.103
regulation of phosphate metabolic process GO:0019220 349 0.100
sensory perception of pain GO:0019233 73 0.098
transcription from rna polymerase ii promoter GO:0006366 252 0.098
g protein coupled receptor signaling pathway GO:0007186 242 0.096
organic substance catabolic process GO:1901575 316 0.096
response to biotic stimulus GO:0009607 226 0.094
lipid metabolic process GO:0006629 283 0.093
positive regulation of cell differentiation GO:0045597 217 0.090
Mouse
response to nutrient levels GO:0031667 370 0.090
positive regulation of cellular component movement GO:0051272 102 0.089
response to carbohydrate GO:0009743 183 0.089
positive regulation of immune system process GO:0002684 90 0.088
localization of cell GO:0051674 202 0.088
divalent metal ion transport GO:0070838 132 0.088
positive regulation of cell development GO:0010720 176 0.087
Mouse
regulation of intracellular signal transduction GO:1902531 218 0.085
regulation of immunoglobulin production GO:0002637 4 0.085
multicellular organismal reproductive process GO:0048609 233 0.085
response to transforming growth factor beta GO:0071559 46 0.084
Human
multi organism reproductive process GO:0044703 262 0.083
regulation of anatomical structure size GO:0090066 135 0.081
amine metabolic process GO:0009308 38 0.081
developmental induction GO:0031128 2 0.080
regulation of peptide secretion GO:0002791 82 0.080
Rat
macromolecule localization GO:0033036 252 0.080
regulation of apoptotic process GO:0042981 335 0.079
peptide hormone secretion GO:0030072 84 0.079
Rat
regulation of neurogenesis GO:0050767 247 0.079
acid secretion GO:0046717 48 0.077
nitrogen compound transport GO:0071705 229 0.077
Rat
erk1 and erk2 cascade GO:0070371 48 0.077
response to organophosphorus GO:0046683 102 0.076
regulation of cellular component movement GO:0051270 150 0.076
single organism reproductive process GO:0044702 297 0.074
regulation of protein metabolic process GO:0051246 289 0.074
ion homeostasis GO:0050801 212 0.073
positive regulation of cell migration GO:0030335 96 0.071
lymphocyte activation GO:0046649 43 0.071
insulin secretion GO:0030073 69 0.070
Rat
response to nicotine GO:0035094 51 0.070
response to extracellular stimulus GO:0009991 380 0.070
membrane organization GO:0061024 94 0.069
hormone transport GO:0009914 121 0.069
Rat
locomotion GO:0040011 237 0.069
cell type specific apoptotic process GO:0097285 134 0.069
sex differentiation GO:0007548 113 0.068
neuropeptide signaling pathway GO:0007218 29 0.067
regulation of peptide hormone secretion GO:0090276 80 0.067
Rat
leukocyte activation involved in immune response GO:0002366 16 0.067
positive regulation of phosphate metabolic process GO:0045937 262 0.067
response to external biotic stimulus GO:0043207 221 0.065
nucleic acid templated transcription GO:0097659 379 0.064
regulation of homeostatic process GO:0032844 101 0.064
phasic smooth muscle contraction GO:0014821 3 0.064
secretion GO:0046903 307 0.064
Rat
response to growth factor GO:0070848 189 0.064
Human
muscle system process GO:0003012 115 0.063
homeostatic process GO:0042592 331 0.063
regulation of transmembrane transport GO:0034762 122 0.063
cellular response to organic cyclic compound GO:0071407 202 0.062
Human
cellular component biogenesis GO:0044085 368 0.061
positive regulation of developmental process GO:0051094 283 0.060
Mouse
organic hydroxy compound biosynthetic process GO:1901617 51 0.060
cellular response to hormone stimulus GO:0032870 247 0.060
cellular divalent inorganic cation homeostasis GO:0072503 162 0.060
neuron death GO:0070997 127 0.059
regulation of programmed cell death GO:0043067 341 0.059
monocarboxylic acid metabolic process GO:0032787 152 0.059
regulation of blood vessel size GO:0050880 89 0.058
response to alkaloid GO:0043279 132 0.058
mapk cascade GO:0000165 140 0.058
regulation of rna biosynthetic process GO:2001141 381 0.058
positive regulation of signal transduction GO:0009967 175 0.056
rna metabolic process GO:0016070 406 0.056
negative regulation of signaling GO:0023057 157 0.056
Rat
regulation of signal transduction GO:0009966 318 0.056
response to decreased oxygen levels GO:0036293 237 0.056
vascular process in circulatory system GO:0003018 96 0.055
Human
response to peptide hormone GO:0043434 278 0.055
development of primary sexual characteristics GO:0045137 107 0.055
second messenger mediated signaling GO:0019932 51 0.055
Human
positive regulation of molecular function GO:0044093 230 0.054
divalent inorganic cation transport GO:0072511 134 0.053
cation transmembrane transport GO:0098655 263 0.053
circulatory system process GO:0003013 183 0.053
Human
calcium ion transport GO:0006816 131 0.053
cellular metal ion homeostasis GO:0006875 172 0.052
programmed cell death GO:0012501 392 0.052
female pregnancy GO:0007565 122 0.051
organophosphate metabolic process GO:0019637 370 0.051
regulation of membrane potential GO:0042391 110 0.051
biological adhesion GO:0022610 110 0.050
regulation of organ formation GO:0003156 2 0.049
metal ion transport GO:0030001 289 0.049
cellular amine metabolic process GO:0044106 38 0.049
small molecule biosynthetic process GO:0044283 124 0.049
neuron projection development GO:0031175 273 0.049
neuron differentiation GO:0030182 368 0.049
cell projection morphogenesis GO:0048858 123 0.048
amine transport GO:0015837 57 0.048
single organism intracellular transport GO:1902582 166 0.048
reproductive structure development GO:0048608 128 0.048
regulation of kinase activity GO:0043549 117 0.048
calcium mediated signaling GO:0019722 23 0.048
gonad development GO:0008406 104 0.047
regulation of ion transmembrane transport GO:0034765 121 0.047
negative regulation of cell death GO:0060548 229 0.047
regulation of tube size GO:0035150 89 0.047
carboxylic acid metabolic process GO:0019752 289 0.046
regulation of calcium ion transport GO:0051924 77 0.045
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.045
behavior GO:0007610 205 0.045
organic anion transport GO:0015711 132 0.044
cellular response to steroid hormone stimulus GO:0071383 93 0.044
response to cocaine GO:0042220 39 0.043
transmembrane transport GO:0055085 412 0.043
cardiovascular system development GO:0072358 134 0.043
regulation of vesicle mediated transport GO:0060627 81 0.043
positive regulation of mapk cascade GO:0043410 92 0.042
axon development GO:0061564 96 0.042
myeloid leukocyte differentiation GO:0002573 20 0.042
response to oxygen levels GO:0070482 265 0.042
positive regulation of blood circulation GO:1903524 65 0.042
regulation of cell development GO:0060284 263 0.041
Mouse
cell projection organization GO:0030030 302 0.041
positive regulation of protein modification process GO:0031401 142 0.041
developmental process involved in reproduction GO:0003006 159 0.041
cellular ketone metabolic process GO:0042180 51 0.041
establishment of protein localization GO:0045184 141 0.040
positive regulation of gene expression GO:0010628 244 0.040
central nervous system development GO:0007417 311 0.040
response to ketone GO:1901654 182 0.040
ossification GO:0001503 70 0.040
leukocyte mediated immunity GO:0002443 28 0.039
leukocyte differentiation GO:0002521 30 0.039
ion transmembrane transport GO:0034220 365 0.039
regulation of response to stress GO:0080134 126 0.039
negative regulation of metabolic process GO:0009892 331 0.039
single organism carbohydrate metabolic process GO:0044723 118 0.039
metal ion homeostasis GO:0055065 186 0.039
organ induction GO:0001759 1 0.038
gamete generation GO:0007276 124 0.038
regulation of mapk cascade GO:0043408 116 0.038
alcohol biosynthetic process GO:0046165 38 0.037
regulation of multicellular organismal development GO:2000026 376 0.037
vesicle mediated transport GO:0016192 181 0.037
cellular response to glucocorticoid stimulus GO:0071385 68 0.037
protein transport GO:0015031 132 0.036
positive regulation of biosynthetic process GO:0009891 319 0.036
positive regulation of kinase activity GO:0033674 77 0.036
single organism biosynthetic process GO:0044711 342 0.036
cellular protein localization GO:0034613 122 0.036
positive regulation of synaptic transmission GO:0050806 62 0.036
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.035
protein complex biogenesis GO:0070271 263 0.035
regulation of nucleic acid templated transcription GO:1903506 380 0.035
learning or memory GO:0007611 90 0.035
regulation of protein modification process GO:0031399 194 0.035
steroid biosynthetic process GO:0006694 48 0.034
response to metal ion GO:0010038 253 0.034
cellular ion homeostasis GO:0006873 184 0.034
cellular cation homeostasis GO:0030003 180 0.034
negative regulation of transport GO:0051051 136 0.034
Rat
cognition GO:0050890 92 0.034
response to inorganic substance GO:0010035 377 0.034
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.034
negative regulation of neuron death GO:1901215 69 0.034
cellular homeostasis GO:0019725 252 0.034
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.033
inorganic cation transmembrane transport GO:0098662 202 0.033
response to camp GO:0051591 91 0.033
single organism cellular localization GO:1902580 102 0.033
defense response GO:0006952 194 0.033
negative regulation of programmed cell death GO:0043069 183 0.033
regulation of transferase activity GO:0051338 123 0.033
positive regulation of cellular component organization GO:0051130 200 0.033
regulation of peptide transport GO:0090087 87 0.033
Rat
macromolecular complex subunit organization GO:0043933 339 0.032
circulatory system development GO:0072359 134 0.032
regulation of cell motility GO:2000145 131 0.032
cellular response to stress GO:0033554 269 0.032
positive regulation of hormone secretion GO:0046887 65 0.032
regulation of catalytic activity GO:0050790 304 0.032
response to estradiol GO:0032355 164 0.032
positive regulation of neuron differentiation GO:0045666 126 0.032
sequestering of calcium ion GO:0051208 8 0.032
response to hypoxia GO:0001666 231 0.032
calcium ion homeostasis GO:0055074 162 0.032
glial cell differentiation GO:0010001 65 0.031
response to xenobiotic stimulus GO:0009410 23 0.031
regulation of cell proliferation GO:0042127 359 0.031
cellular component assembly GO:0022607 360 0.031
protein complex assembly GO:0006461 263 0.031
positive regulation of protein phosphorylation GO:0001934 135 0.031
tumor necrosis factor biosynthetic process GO:0042533 1 0.031
cellular chemical homeostasis GO:0055082 247 0.030
protein complex subunit organization GO:0071822 302 0.030
organic acid metabolic process GO:0006082 292 0.030
negative regulation of ion transmembrane transport GO:0034766 16 0.030
positive regulation of leukocyte degranulation GO:0043302 4 0.030
negative regulation of secretion by cell GO:1903531 72 0.030
Rat
female sex differentiation GO:0046660 59 0.030
response to insulin GO:0032868 133 0.030
positive regulation of transferase activity GO:0051347 81 0.029
negative regulation of response to external stimulus GO:0032102 37 0.029
positive regulation of immune response GO:0050778 42 0.029
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.029
alcohol metabolic process GO:0006066 77 0.029
carbohydrate metabolic process GO:0005975 130 0.029
response to hexose GO:0009746 144 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
inorganic ion transmembrane transport GO:0098660 229 0.029
hematopoietic or lymphoid organ development GO:0048534 36 0.029
regulation of leukocyte mediated immunity GO:0002703 19 0.029
organophosphate biosynthetic process GO:0090407 143 0.029
regulation of mononuclear cell proliferation GO:0032944 26 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.028
blood circulation GO:0008015 183 0.027
Human
dephosphorylation GO:0016311 98 0.027
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.027
Human
digestive system development GO:0055123 41 0.027
neurotransmitter transport GO:0006836 42 0.027
regulation of insulin secretion GO:0050796 65 0.027
Rat
multi multicellular organism process GO:0044706 138 0.027
acute inflammatory response GO:0002526 58 0.027
negative regulation of ion transport GO:0043271 51 0.027
wound healing GO:0042060 122 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
positive regulation of cell death GO:0010942 184 0.027
positive regulation of peptide secretion GO:0002793 52 0.026
sensory organ development GO:0007423 74 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
positive regulation of homeostatic process GO:0032846 49 0.026
positive regulation of exocytosis GO:0045921 19 0.026
exocytosis GO:0006887 60 0.026
regulation of response to external stimulus GO:0032101 106 0.026
regulation of lipid metabolic process GO:0019216 68 0.026
cell morphogenesis GO:0000902 142 0.026
jak stat cascade GO:0007259 26 0.025
phospholipid metabolic process GO:0006644 61 0.025
response to toxic substance GO:0009636 133 0.025
intracellular protein transport GO:0006886 79 0.025
response to food GO:0032094 27 0.025
macromolecular complex assembly GO:0065003 273 0.025
negative regulation of nervous system development GO:0051961 79 0.025
regulation of protein kinase activity GO:0045859 105 0.025
negative regulation of response to wounding GO:1903035 23 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
negative regulation of chronic inflammatory response GO:0002677 2 0.024
regulation of defecation GO:2000292 1 0.024
glucose homeostasis GO:0042593 75 0.024
glycerolipid metabolic process GO:0046486 67 0.024
brain development GO:0007420 247 0.023
cellular response to corticosteroid stimulus GO:0071384 69 0.023
regulation of pancreatic stellate cell proliferation GO:2000229 2 0.023
regulation of neuron differentiation GO:0045664 208 0.023
regulation of immune effector process GO:0002697 32 0.023
cytosolic calcium ion homeostasis GO:0051480 140 0.023
divalent inorganic cation homeostasis GO:0072507 165 0.023
oxoacid metabolic process GO:0043436 290 0.023
positive regulation of cellular component biogenesis GO:0044089 55 0.023
cellular macromolecule localization GO:0070727 122 0.023
negative regulation of biosynthetic process GO:0009890 168 0.023
epithelium development GO:0060429 96 0.023
visual learning GO:0008542 8 0.023
organ formation GO:0048645 3 0.023
response to nutrient GO:0007584 248 0.023
regulation of transcription dna templated GO:0006355 374 0.023
intracellular transport GO:0046907 185 0.022
hemopoiesis GO:0030097 34 0.022
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.022
cell morphogenesis involved in differentiation GO:0000904 119 0.022
single organism membrane organization GO:0044802 74 0.022
rna biosynthetic process GO:0032774 380 0.022
single organism organelle organization GO:1902589 180 0.022
peptide secretion GO:0002790 86 0.022
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.022
response to monosaccharide GO:0034284 159 0.021
peptidyl tyrosine phosphorylation GO:0018108 72 0.021
sexual reproduction GO:0019953 148 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
immune system development GO:0002520 41 0.021
regulation of ion transmembrane transporter activity GO:0032412 48 0.021
gamma aminobutyric acid transport GO:0015812 8 0.021
organelle organization GO:0006996 266 0.021
Mouse
negative regulation of homeostatic process GO:0032845 47 0.021
cell part morphogenesis GO:0032990 123 0.021
response to glucocorticoid GO:0051384 223 0.021
amide transport GO:0042886 105 0.020
Rat
regulation of response to wounding GO:1903034 69 0.020
digestive tract development GO:0048565 39 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
regulation of neurological system process GO:0031644 43 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
regulation of cellular component organization GO:0051128 368 0.020
Mouse
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
inflammatory response GO:0006954 150 0.020
ras protein signal transduction GO:0007265 29 0.020
regulation of catabolic process GO:0009894 113 0.020
negative regulation of multicellular organismal process GO:0051241 203 0.020
reactive nitrogen species metabolic process GO:2001057 1 0.020
head development GO:0060322 247 0.019
regulation of transmembrane transporter activity GO:0022898 49 0.019
ovulation cycle process GO:0022602 50 0.019
cellular response to peptide GO:1901653 133 0.019
synaptic transmission cholinergic GO:0007271 11 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
regulation of sensory perception GO:0051931 29 0.019
taxis GO:0042330 67 0.019
growth GO:0040007 165 0.019
negative regulation of neuron differentiation GO:0045665 62 0.019
regulation of transporter activity GO:0032409 50 0.018
regulation of epithelial cell proliferation GO:0050678 49 0.018
memory GO:0007613 54 0.018
choline transport GO:0015871 4 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
heterocycle catabolic process GO:0046700 167 0.018
regulation of erk1 and erk2 cascade GO:0070372 41 0.018
cellular response to oxygen levels GO:0071453 60 0.018
response to purine containing compound GO:0014074 126 0.018
myeloid cell differentiation GO:0030099 22 0.018
positive regulation of leukocyte activation GO:0002696 30 0.018
cellular carbohydrate metabolic process GO:0044262 72 0.018
immunoglobulin mediated immune response GO:0016064 4 0.018
peptide transport GO:0015833 97 0.018
Rat
response to oxidative stress GO:0006979 186 0.018
vasoconstriction GO:0042310 54 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
regulation of organic acid transport GO:0032890 35 0.018
tube development GO:0035295 89 0.018
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.018
cytokine production GO:0001816 61 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
regulation of amine transport GO:0051952 54 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
endoplasmic reticulum to cytosol transport GO:1903513 4 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
positive regulation of insulin secretion GO:0032024 36 0.017
macromolecule catabolic process GO:0009057 58 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
Human
myeloid cell activation involved in immune response GO:0002275 13 0.017
synaptic transmission glutamatergic GO:0035249 33 0.017
development of primary female sexual characteristics GO:0046545 56 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
response to pain GO:0048265 11 0.017
regulation of organelle organization GO:0033043 80 0.016
Mouse
steroid metabolic process GO:0008202 73 0.016
aging GO:0007568 241 0.016
male sex differentiation GO:0046661 64 0.016
male gamete generation GO:0048232 99 0.016
regulation of system process GO:0044057 208 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
Human
peptidyl tyrosine modification GO:0018212 72 0.016
cellular response to lipid GO:0071396 201 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
regulation of ion homeostasis GO:2000021 63 0.016
carbohydrate homeostasis GO:0033500 75 0.016
cytokine biosynthetic process GO:0042089 3 0.016
negative regulation of molecular function GO:0044092 133 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
cytoskeleton organization GO:0007010 111 0.016
neuron apoptotic process GO:0051402 88 0.016
response to glucose GO:0009749 136 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
regulation of cytokine biosynthetic process GO:0042035 3 0.015
regulation of neuron projection development GO:0010975 161 0.015
response to ammonium ion GO:0060359 71 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
male gonad development GO:0008584 59 0.015
positive regulation of response to food GO:0032097 3 0.015
catabolic process GO:0009056 351 0.015
cellular biogenic amine metabolic process GO:0006576 30 0.015
regulation of developmental growth GO:0048638 45 0.015
negative regulation of calcium ion import GO:0090281 2 0.015
regulation of protein catabolic process GO:0042176 16 0.015
adult locomotory behavior GO:0008344 4 0.015
negative regulation of neurogenesis GO:0050768 78 0.015
dendrite development GO:0016358 72 0.015
spermatogenesis GO:0007283 99 0.015
regulation of cell adhesion GO:0030155 52 0.014
regulation of intracellular transport GO:0032386 65 0.014
regulation of muscle contraction GO:0006937 53 0.014
hormone biosynthetic process GO:0042446 25 0.014
regulation of leukocyte degranulation GO:0043300 6 0.014
learning GO:0007612 33 0.014
tolerance induction dependent upon immune response GO:0002461 2 0.014
hair cell differentiation GO:0035315 2 0.014
regulation of cellular component biogenesis GO:0044087 86 0.014
positive regulation of peptide hormone secretion GO:0090277 50 0.014
response to radiation GO:0009314 137 0.014
rho protein signal transduction GO:0007266 11 0.014
innate immune response GO:0045087 35 0.014
organic hydroxy compound transport GO:0015850 77 0.014
cell cell signaling involved in cell fate commitment GO:0045168 2 0.014
positive regulation of epithelial cell proliferation GO:0050679 32 0.014
regulation of cation channel activity GO:2001257 23 0.014
insecticide metabolic process GO:0017143 4 0.014
regulation of actin filament based process GO:0032970 42 0.014
regulation of cell migration GO:0030334 128 0.014
single organism cell adhesion GO:0098602 46 0.014
monoamine transport GO:0015844 43 0.014
regulation of sensory perception of pain GO:0051930 29 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
negative regulation of cell communication GO:0010648 158 0.013
Rat
regulation of cell projection organization GO:0031344 175 0.013
protein oligomerization GO:0051259 191 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.013

Pde3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.027
central nervous system disease DOID:331 0 0.020
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
disease of cellular proliferation DOID:14566 0 0.015