Rattus norvegicus

78 known processes

Irf3

interferon regulatory factor 3

(Aliases: MGC94729)

Irf3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
alternative mrna splicing via spliceosome GO:0000380 4 0.171
regulation of nucleic acid templated transcription GO:1903506 380 0.134
rna metabolic process GO:0016070 406 0.083
angioblast cell migration GO:0035476 1 0.082
lipid metabolic process GO:0006629 283 0.080
negative regulation of cell communication GO:0010648 158 0.050
single organism biosynthetic process GO:0044711 342 0.050
rna biosynthetic process GO:0032774 380 0.044
regulation of rna biosynthetic process GO:2001141 381 0.044
regulation of molecular function GO:0065009 398 0.040
regulation of rna metabolic process GO:0051252 391 0.040
regulation of mrna splicing via spliceosome GO:0048024 3 0.040
cellular lipid metabolic process GO:0044255 208 0.039
negative regulation of metabolic process GO:0009892 331 0.038
dephosphorylation GO:0016311 98 0.036
transcription dna templated GO:0006351 377 0.036
glycerolipid metabolic process GO:0046486 67 0.036
phosphatidylinositol dephosphorylation GO:0046856 4 0.036
nucleic acid templated transcription GO:0097659 379 0.033
organophosphate biosynthetic process GO:0090407 143 0.030
organelle organization GO:0006996 266 0.030
macromolecule localization GO:0033036 252 0.029
cellular component movement GO:0006928 248 0.029
regulation of cellular component organization GO:0051128 368 0.029
regulation of transcription dna templated GO:0006355 374 0.029
neuron differentiation GO:0030182 368 0.028
organophosphate metabolic process GO:0019637 370 0.028
peptidyl tyrosine modification GO:0018212 72 0.026
localization of cell GO:0051674 202 0.026
cellular amine metabolic process GO:0044106 38 0.026
second messenger mediated signaling GO:0019932 51 0.026
multi organism reproductive process GO:0044703 262 0.025
head development GO:0060322 247 0.025
reproduction GO:0000003 245 0.025
protein phosphorylation GO:0006468 345 0.025
catabolic process GO:0009056 351 0.025
locomotion GO:0040011 237 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
response to atp GO:0033198 13 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
cell motility GO:0048870 202 0.024
cellular component assembly GO:0022607 360 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
single organism catabolic process GO:0044712 283 0.023
actin filament based process GO:0030029 86 0.023
cellular ketone metabolic process GO:0042180 51 0.023
regulation of cell cycle GO:0051726 73 0.022
gluconeogenesis GO:0006094 15 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
response to insulin GO:0032868 133 0.022
ribonucleoside triphosphate metabolic process GO:0009199 141 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
multicellular organism reproduction GO:0032504 233 0.021
response to purine containing compound GO:0014074 126 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
negative regulation of nucleic acid templated transcription GO:1903507 117 0.021
neuron projection development GO:0031175 273 0.021
organonitrogen compound biosynthetic process GO:1901566 167 0.020
apoptotic process GO:0006915 381 0.020
amine metabolic process GO:0009308 38 0.020
small molecule biosynthetic process GO:0044283 124 0.020
homeostatic process GO:0042592 331 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
cytoplasmic transport GO:0016482 115 0.018
endocytosis GO:0006897 84 0.018
regulation of cell differentiation GO:0045595 320 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
behavior GO:0007610 205 0.018
response to external biotic stimulus GO:0043207 221 0.018
response to acid chemical GO:0001101 222 0.018
regulation of organelle organization GO:0033043 80 0.018
intracellular transport GO:0046907 185 0.018
cellular cation homeostasis GO:0030003 180 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
cellular homeostasis GO:0019725 252 0.018
heart morphogenesis GO:0003007 3 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
negative regulation of gluconeogenesis GO:0045721 1 0.017
cytoskeleton organization GO:0007010 111 0.017
nitrogen compound transport GO:0071705 229 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
protein autophosphorylation GO:0046777 66 0.017
positive regulation of transport GO:0051050 245 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
nucleotide metabolic process GO:0009117 279 0.017
single organism reproductive process GO:0044702 297 0.016
phosphatidylethanolamine metabolic process GO:0046337 1 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
heart process GO:0003015 57 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
ion transmembrane transport GO:0034220 365 0.016
spindle organization GO:0007051 2 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
organic substance catabolic process GO:1901575 316 0.016
signal release GO:0023061 145 0.016
secretion GO:0046903 307 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
regulation of gluconeogenesis GO:0006111 4 0.016
cytoskeleton dependent cytokinesis GO:0061640 2 0.016
regulation of cellular localization GO:0060341 263 0.016
mrna 3 end processing GO:0031124 1 0.016
response to cytokine GO:0034097 215 0.016
anterior posterior pattern specification GO:0009952 1 0.016
organic acid metabolic process GO:0006082 292 0.016
nucleoside metabolic process GO:0009116 179 0.016
nucleotide biosynthetic process GO:0009165 98 0.016
reproductive process GO:0022414 372 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
secretion by cell GO:0032940 248 0.015
cellular carbohydrate metabolic process GO:0044262 72 0.015
response to peptide GO:1901652 292 0.015
response to aluminum ion GO:0010044 10 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
cytokinetic process GO:0032506 1 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
sexual reproduction GO:0019953 148 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.014
brain development GO:0007420 247 0.014
regulation of nervous system development GO:0051960 264 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
regulation of multicellular organismal development GO:2000026 376 0.014
regulation of response to external stimulus GO:0032101 106 0.014
regulation of anatomical structure size GO:0090066 135 0.014
aromatic compound catabolic process GO:0019439 168 0.014
dna metabolic process GO:0006259 96 0.014
response to ammonium ion GO:0060359 71 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
actin cytoskeleton organization GO:0030036 73 0.014
nucleoside monophosphate metabolic process GO:0009123 93 0.014
response to monosaccharide GO:0034284 159 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
response to oxygen levels GO:0070482 265 0.014
response to bacterium GO:0009617 200 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
transmembrane transport GO:0055085 412 0.013
response to fluoride GO:1902617 3 0.013
protein localization GO:0008104 191 0.013
cell projection organization GO:0030030 302 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
carbohydrate metabolic process GO:0005975 130 0.013
ribonucleoside monophosphate metabolic process GO:0009161 88 0.013
regeneration GO:0031099 163 0.013
response to radiation GO:0009314 137 0.013
retinal ganglion cell axon guidance GO:0031290 1 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
response to organophosphorus GO:0046683 102 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
regulation of signal transduction GO:0009966 318 0.013
sequestering of metal ion GO:0051238 9 0.013
lipid biosynthetic process GO:0008610 128 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
hematopoietic progenitor cell differentiation GO:0002244 2 0.013
maintenance of location GO:0051235 17 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
regulation of protein maturation GO:1903317 50 0.013
multicellular organism growth GO:0035264 1 0.013
cellular catabolic process GO:0044248 295 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
cell cycle checkpoint GO:0000075 2 0.013
cation transport GO:0006812 382 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
carbohydrate biosynthetic process GO:0016051 42 0.012
ribonucleoside monophosphate catabolic process GO:0009158 55 0.012
carboxylic acid metabolic process GO:0019752 289 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
negative regulation of signaling GO:0023057 157 0.012
gamete generation GO:0007276 124 0.012
embryonic pattern specification GO:0009880 1 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
single organism organelle organization GO:1902589 180 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
regulation of cytoskeleton organization GO:0051493 49 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
single organism intracellular transport GO:1902582 166 0.012
programmed cell death GO:0012501 392 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
synaptic transmission GO:0007268 235 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
intra golgi vesicle mediated transport GO:0006891 3 0.012
protein complex biogenesis GO:0070271 263 0.012
hexose biosynthetic process GO:0019319 15 0.011
regulation of hormone secretion GO:0046883 106 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
positive regulation of gene expression GO:0010628 244 0.011
regulation of catalytic activity GO:0050790 304 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
proteolysis GO:0006508 175 0.011
response to peptide hormone GO:0043434 278 0.011
nucleoside monophosphate catabolic process GO:0009125 56 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
oxoacid metabolic process GO:0043436 290 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
alcohol metabolic process GO:0006066 77 0.011
vesicle mediated transport GO:0016192 181 0.011
cell cell signaling GO:0007267 335 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
chemical homeostasis GO:0048878 292 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
mrna processing GO:0006397 14 0.011
ras protein signal transduction GO:0007265 29 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
metal ion transport GO:0030001 289 0.011
purine nucleoside monophosphate catabolic process GO:0009128 55 0.011
regulation of transferase activity GO:0051338 123 0.011
macromolecular complex assembly GO:0065003 273 0.011
cation homeostasis GO:0055080 195 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
organophosphate catabolic process GO:0046434 148 0.011
neuromuscular process GO:0050905 2 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
regulation of neuron projection development GO:0010975 161 0.011
regulation of organ formation GO:0003156 2 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
single organism behavior GO:0044708 130 0.010
peptidyl tyrosine phosphorylation GO:0018108 72 0.010
negative regulation of secretion GO:0051048 82 0.010
positive regulation of cellular amine metabolic process GO:0033240 3 0.010
anion transport GO:0006820 178 0.010
response to other organism GO:0051707 220 0.010
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.010
cellular component biogenesis GO:0044085 368 0.010
purine containing compound metabolic process GO:0072521 253 0.010
metal ion homeostasis GO:0055065 186 0.010
regulation of secretion by cell GO:1903530 208 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.010
positive regulation of secretion GO:0051047 140 0.010
positive regulation of developmental process GO:0051094 283 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010
oxidation reduction process GO:0055114 304 0.010
cellular chemical homeostasis GO:0055082 247 0.010
synaptic vesicle endocytosis GO:0048488 4 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
positive regulation of molecular function GO:0044093 230 0.010
neuron development GO:0048666 286 0.010

Irf3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.145
retinal degeneration DOID:8466 0 0.145
sensory system disease DOID:0050155 0 0.145
disease of anatomical entity DOID:7 0 0.145
retinitis pigmentosa DOID:10584 0 0.145
eye and adnexa disease DOID:1492 0 0.145
nervous system disease DOID:863 0 0.145
eye disease DOID:5614 0 0.145
disease of metabolism DOID:0014667 0 0.036
inherited metabolic disorder DOID:655 0 0.036
carbohydrate metabolic disorder DOID:2978 0 0.025
muscular disease DOID:0080000 0 0.014
musculoskeletal system disease DOID:17 0 0.014