Rattus norvegicus

0 known processes

Tnik

TRAF2 and NCK interacting kinase

(Aliases: RGD1561817)

Tnik biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transmembrane transport GO:0098655 263 0.158
locomotion GO:0040011 237 0.099
intracellular signal transduction GO:0035556 314 0.090
regulation of cellular component organization GO:0051128 368 0.082
anatomical structure morphogenesis GO:0009653 298 0.081
Rat
single organism biosynthetic process GO:0044711 342 0.079
neuron projection development GO:0031175 273 0.075
Rat
cellular component assembly GO:0022607 360 0.072
transcription dna templated GO:0006351 377 0.071
ion transmembrane transport GO:0034220 365 0.069
Rat
regulation of transcription dna templated GO:0006355 374 0.069
response to hypoxia GO:0001666 231 0.068
regulation of signal transduction GO:0009966 318 0.067
Rat
rna biosynthetic process GO:0032774 380 0.065
cation transport GO:0006812 382 0.061
inorganic cation transmembrane transport GO:0098662 202 0.061
transmembrane transport GO:0055085 412 0.060
Rat
positive regulation of signaling GO:0023056 270 0.060
cell projection organization GO:0030030 302 0.060
Rat
protein phosphorylation GO:0006468 345 0.059
positive regulation of ion transport GO:0043270 94 0.058
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.058
regulation of multicellular organismal development GO:2000026 376 0.055
neuron differentiation GO:0030182 368 0.053
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.053
regulation of neurogenesis GO:0050767 247 0.053
oxoacid metabolic process GO:0043436 290 0.051
metal ion transport GO:0030001 289 0.050
cellular component biogenesis GO:0044085 368 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.049
cellular component movement GO:0006928 248 0.048
organophosphate metabolic process GO:0019637 370 0.048
regulation of cellular localization GO:0060341 263 0.047
regulation of ion transport GO:0043269 245 0.047
Rat
response to nutrient GO:0007584 248 0.047
carboxylic acid metabolic process GO:0019752 289 0.047
organic acid metabolic process GO:0006082 292 0.047
regulation of phosphate metabolic process GO:0019220 349 0.046
homeostatic process GO:0042592 331 0.046
rna metabolic process GO:0016070 406 0.046
positive regulation of cell communication GO:0010647 271 0.045
positive regulation of biosynthetic process GO:0009891 319 0.045
cellular response to endogenous stimulus GO:0071495 377 0.044
neuron development GO:0048666 286 0.044
Rat
response to oxygen levels GO:0070482 265 0.043
positive regulation of response to stimulus GO:0048584 285 0.043
apoptotic process GO:0006915 381 0.043
response to inorganic substance GO:0010035 377 0.043
intracellular transport GO:0046907 185 0.042
regulation of neuron differentiation GO:0045664 208 0.042
regulation of nervous system development GO:0051960 264 0.041
enzyme linked receptor protein signaling pathway GO:0007167 116 0.041
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.040
Rat
response to decreased oxygen levels GO:0036293 237 0.040
learning or memory GO:0007611 90 0.040
positive regulation of cellular biosynthetic process GO:0031328 295 0.040
positive regulation of phosphorus metabolic process GO:0010562 262 0.039
chemical homeostasis GO:0048878 292 0.039
protein complex subunit organization GO:0071822 302 0.039
inorganic ion transmembrane transport GO:0098660 229 0.039
neuron projection morphogenesis GO:0048812 122 0.039
Rat
cell growth GO:0016049 104 0.038
cellular component morphogenesis GO:0032989 155 0.038
Rat
positive regulation of gene expression GO:0010628 244 0.038
axon development GO:0061564 96 0.038
regulation of cell development GO:0060284 263 0.038
single organism intracellular transport GO:1902582 166 0.037
macromolecular complex assembly GO:0065003 273 0.037
regulation of rna biosynthetic process GO:2001141 381 0.037
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.037
lipid biosynthetic process GO:0008610 128 0.036
cellular response to oxygen containing compound GO:1901701 386 0.034
regulation of rna metabolic process GO:0051252 391 0.033
reproductive process GO:0022414 372 0.033
positive regulation of molecular function GO:0044093 230 0.032
response to carbohydrate GO:0009743 183 0.032
macromolecular complex subunit organization GO:0043933 339 0.032
regulation of metal ion transport GO:0010959 118 0.032
single organism reproductive process GO:0044702 297 0.032
positive regulation of transport GO:0051050 245 0.032
nucleoside phosphate metabolic process GO:0006753 283 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
organelle organization GO:0006996 266 0.032
cell projection morphogenesis GO:0048858 123 0.031
Rat
male mating behavior GO:0060179 3 0.031
cellular response to hormone stimulus GO:0032870 247 0.031
cellular chemical homeostasis GO:0055082 247 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
transcription from rna polymerase ii promoter GO:0006366 252 0.030
regulation of phosphorylation GO:0042325 248 0.030
small gtpase mediated signal transduction GO:0007264 36 0.030
regulation of programmed cell death GO:0043067 341 0.030
positive regulation of cellular component organization GO:0051130 200 0.030
cellular divalent inorganic cation homeostasis GO:0072503 162 0.030
cell part morphogenesis GO:0032990 123 0.029
Rat
cellular homeostasis GO:0019725 252 0.029
cellular catabolic process GO:0044248 295 0.029
regulation of catalytic activity GO:0050790 304 0.029
ras protein signal transduction GO:0007265 29 0.029
regulation of phosphorus metabolic process GO:0051174 349 0.029
protein complex biogenesis GO:0070271 263 0.029
cellular ketone metabolic process GO:0042180 51 0.029
nucleic acid templated transcription GO:0097659 379 0.028
regulation of apoptotic process GO:0042981 335 0.028
positive regulation of developmental process GO:0051094 283 0.028
positive regulation of rna metabolic process GO:0051254 203 0.028
catabolic process GO:0009056 351 0.028
single organism catabolic process GO:0044712 283 0.028
regulation of neuron projection development GO:0010975 161 0.028
reproduction GO:0000003 245 0.028
cellular calcium ion homeostasis GO:0006874 160 0.028
calcium ion homeostasis GO:0055074 162 0.028
membrane depolarization during action potential GO:0086010 1 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
protein complex assembly GO:0006461 263 0.026
regulation of membrane potential GO:0042391 110 0.026
amine metabolic process GO:0009308 38 0.026
cellular amine metabolic process GO:0044106 38 0.026
secretion GO:0046903 307 0.026
regulation of cell differentiation GO:0045595 320 0.026
cell cell signaling GO:0007267 335 0.025
Rat
neurological system process GO:0050877 219 0.025
organophosphate biosynthetic process GO:0090407 143 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
cellular metal ion homeostasis GO:0006875 172 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.024
regulation of homeostatic process GO:0032844 101 0.024
regulation of molecular function GO:0065009 398 0.024
Rat
response to nutrient levels GO:0031667 370 0.024
response to monosaccharide GO:0034284 159 0.024
multi organism reproductive process GO:0044703 262 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
regulation of protein modification process GO:0031399 194 0.023
regulation of nucleic acid templated transcription GO:1903506 380 0.023
regulation of protein phosphorylation GO:0001932 183 0.023
nucleotide metabolic process GO:0009117 279 0.023
behavior GO:0007610 205 0.023
myelination GO:0042552 39 0.023
cellular response to lipid GO:0071396 201 0.023
response to peptide GO:1901652 292 0.022
maintenance of location GO:0051235 17 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
regulation of cell projection organization GO:0031344 175 0.022
response to metal ion GO:0010038 253 0.022
response to extracellular stimulus GO:0009991 380 0.022
calcium ion transmembrane transport GO:0070588 70 0.022
ion homeostasis GO:0050801 212 0.022
developmental growth GO:0048589 100 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
response to biotic stimulus GO:0009607 226 0.021
regulation of system process GO:0044057 208 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
cell morphogenesis involved in differentiation GO:0000904 119 0.021
Rat
multicellular organismal reproductive process GO:0048609 233 0.021
programmed cell death GO:0012501 392 0.021
monovalent inorganic cation transport GO:0015672 172 0.021
cell morphogenesis GO:0000902 142 0.021
Rat
axonogenesis GO:0007409 71 0.021
oxidation reduction process GO:0055114 304 0.021
central nervous system development GO:0007417 311 0.021
cellular ion homeostasis GO:0006873 184 0.020
muscle system process GO:0003012 115 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
response to acid chemical GO:0001101 222 0.020
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
cell migration GO:0016477 197 0.020
regulation of vesicle mediated transport GO:0060627 81 0.020
organic substance catabolic process GO:1901575 316 0.019
membrane depolarization during cardiac muscle cell action potential GO:0086012 1 0.019
aging GO:0007568 241 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
axis specification GO:0009798 4 0.019
peptidyl amino acid modification GO:0018193 126 0.019
nitrogen compound transport GO:0071705 229 0.019
regulation of protein metabolic process GO:0051246 289 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
response to purine containing compound GO:0014074 126 0.019
purine containing compound metabolic process GO:0072521 253 0.019
sexual reproduction GO:0019953 148 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
response to growth factor GO:0070848 189 0.019
synaptic growth at neuromuscular junction GO:0051124 1 0.019
biological adhesion GO:0022610 110 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
neuron death GO:0070997 127 0.019
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.019
cellular lipid metabolic process GO:0044255 208 0.018
head development GO:0060322 247 0.018
regulation of cell proliferation GO:0042127 359 0.018
second messenger mediated signaling GO:0019932 51 0.018
localization of cell GO:0051674 202 0.018
multicellular organismal signaling GO:0035637 44 0.018
response to glucose GO:0009749 136 0.018
cell adhesion GO:0007155 110 0.018
tissue development GO:0009888 252 0.018
response to peptide hormone GO:0043434 278 0.018
response to lipopolysaccharide GO:0032496 191 0.018
choline transport GO:0015871 4 0.018
positive regulation of cell death GO:0010942 184 0.018
response to cytokine GO:0034097 215 0.017
response to external biotic stimulus GO:0043207 221 0.017
reproductive system development GO:0061458 128 0.017
response to bacterium GO:0009617 200 0.017
regulation of cellular component movement GO:0051270 150 0.017
macromolecule localization GO:0033036 252 0.017
membrane organization GO:0061024 94 0.017
organophosphate catabolic process GO:0046434 148 0.017
regulation of secretion GO:0051046 224 0.017
positive regulation of cell development GO:0010720 176 0.017
regulation of catabolic process GO:0009894 113 0.017
generation of precursor metabolites and energy GO:0006091 62 0.017
establishment of protein localization GO:0045184 141 0.017
potassium ion transport GO:0006813 97 0.017
sex differentiation GO:0007548 113 0.017
gonad development GO:0008406 104 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
cytoplasmic transport GO:0016482 115 0.016
sequestering of metal ion GO:0051238 9 0.016
growth GO:0040007 165 0.016
negative regulation of metabolic process GO:0009892 331 0.016
regeneration GO:0031099 163 0.016
brain development GO:0007420 247 0.016
circadian regulation of gene expression GO:0032922 3 0.016
cellular cation homeostasis GO:0030003 180 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
sequestering of calcium ion GO:0051208 8 0.016
calcium ion transport GO:0006816 131 0.016
rhythmic process GO:0048511 156 0.016
cognition GO:0050890 92 0.016
response to hexose GO:0009746 144 0.016
development of primary sexual characteristics GO:0045137 107 0.016
response to insulin GO:0032868 133 0.016
protein transport GO:0015031 132 0.016
regulation of hormone levels GO:0010817 187 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
monosaccharide metabolic process GO:0005996 61 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
signal release GO:0023061 145 0.016
response to corticosteroid GO:0031960 235 0.016
ribonucleotide metabolic process GO:0009259 231 0.015
dendrite development GO:0016358 72 0.015
Rat
regulation of intracellular signal transduction GO:1902531 218 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
actin mediated cell contraction GO:0070252 12 0.015
positive regulation of signal transduction GO:0009967 175 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
memory GO:0007613 54 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
regulation of locomotion GO:0040012 148 0.015
carbohydrate metabolic process GO:0005975 130 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.015
negative regulation of signaling GO:0023057 157 0.015
multi multicellular organism process GO:0044706 138 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
actin filament based process GO:0030029 86 0.014
neuronal action potential GO:0019228 35 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
response to oxidative stress GO:0006979 186 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
sodium ion transmembrane transport GO:0035725 67 0.014
action potential GO:0001508 54 0.014
transmission of nerve impulse GO:0019226 42 0.014
divalent inorganic cation transport GO:0072511 134 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
cellular response to stress GO:0033554 269 0.014
cation homeostasis GO:0055080 195 0.014
divalent metal ion transport GO:0070838 132 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
axon ensheathment GO:0008366 40 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
epithelium development GO:0060429 96 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
proteolysis GO:0006508 175 0.013
motor neuron axon guidance GO:0008045 1 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
gastrulation GO:0007369 2 0.013
regulation of cell motility GO:2000145 131 0.013
regulation of cell adhesion GO:0030155 52 0.013
negative regulation of cell death GO:0060548 229 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
multicellular organism growth GO:0035264 1 0.013
metal ion homeostasis GO:0055065 186 0.013
positive regulation of nervous system development GO:0051962 178 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
regulation of cardiac muscle cell action potential GO:0098901 3 0.013
circulatory system process GO:0003013 183 0.013
negative regulation of developmental process GO:0051093 125 0.013
regulation of anatomical structure size GO:0090066 135 0.013
positive regulation of cell projection organization GO:0031346 111 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
multicellular organism reproduction GO:0032504 233 0.012
cell cycle GO:0007049 101 0.012
negative regulation of nervous system development GO:0051961 79 0.012
cellular macromolecule localization GO:0070727 122 0.012
regulation of calcium ion transport GO:0051924 77 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
regulation of axonogenesis GO:0050770 37 0.012
muscle tissue development GO:0060537 58 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
response to calcium ion GO:0051592 59 0.012
response to vitamin GO:0033273 131 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
lipid metabolic process GO:0006629 283 0.012
vesicle mediated transport GO:0016192 181 0.012
anterior posterior pattern specification GO:0009952 1 0.012
embryonic pattern specification GO:0009880 1 0.012
circadian rhythm GO:0007623 88 0.012
cyclic purine nucleotide metabolic process GO:0052652 62 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
response to estrogen GO:0043627 232 0.012
regulation of synaptic transmission GO:0050804 141 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
actin cytoskeleton organization GO:0030036 73 0.012
regulation of cell migration GO:0030334 128 0.011
response to alkaloid GO:0043279 132 0.011
amino acid transport GO:0006865 70 0.011
single organism organelle organization GO:1902589 180 0.011
ensheathment of neurons GO:0007272 40 0.011
gamete generation GO:0007276 124 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
response to hydrogen peroxide GO:0042542 89 0.011
carboxylic acid transport GO:0046942 115 0.011
response to wounding GO:0009611 254 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
spindle organization GO:0007051 2 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
secretion by cell GO:0032940 248 0.011
organic anion transport GO:0015711 132 0.011
muscle structure development GO:0061061 87 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
dendrite morphogenesis GO:0048813 43 0.011
Rat
negative regulation of protein metabolic process GO:0051248 114 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
striated muscle tissue development GO:0014706 58 0.011
negative regulation of transport GO:0051051 136 0.011
regulation of secretion by cell GO:1903530 208 0.011
single organism behavior GO:0044708 130 0.011
cellular response to molecule of bacterial origin GO:0071219 56 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
circulatory system development GO:0072359 134 0.011
positive regulation of locomotion GO:0040017 102 0.011
negative regulation of cell communication GO:0010648 158 0.011
regulation of dendrite development GO:0050773 59 0.011
cytoskeleton dependent cytokinesis GO:0061640 2 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
forebrain development GO:0030900 98 0.010
cytoskeleton organization GO:0007010 111 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
developmental growth involved in morphogenesis GO:0060560 33 0.010
protein oligomerization GO:0051259 191 0.010
regulation of ion homeostasis GO:2000021 63 0.010
cellular protein localization GO:0034613 122 0.010
response to other organism GO:0051707 220 0.010
regulation of small gtpase mediated signal transduction GO:0051056 48 0.010
response to organophosphorus GO:0046683 102 0.010
calcium ion transport into cytosol GO:0060402 38 0.010
small molecule biosynthetic process GO:0044283 124 0.010
regulation of homotypic cell cell adhesion GO:0034110 4 0.010
bmp signaling pathway GO:0030509 4 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
organ regeneration GO:0031100 101 0.010
nucleoside metabolic process GO:0009116 179 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
lipid storage GO:0019915 1 0.010
cellular response to external stimulus GO:0071496 118 0.010
response to ketone GO:1901654 182 0.010

Tnik disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.020
brain disease DOID:936 0 0.020
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
myopathy DOID:423 0 0.019
muscular disease DOID:0080000 0 0.019
musculoskeletal system disease DOID:17 0 0.019
muscle tissue disease DOID:66 0 0.019
disease of metabolism DOID:0014667 0 0.013
cardiovascular system disease DOID:1287 0 0.011