Rattus norvegicus

40 known processes

Nox1

NADPH oxidase 1

Nox1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
homeostatic process GO:0042592 331 0.321
signal transduction by phosphorylation GO:0023014 144 0.258
aging GO:0007568 241 0.228
intracellular signal transduction GO:0035556 314 0.185
positive regulation of phosphate metabolic process GO:0045937 262 0.169
response to glucocorticoid GO:0051384 223 0.149
regulation of phosphate metabolic process GO:0019220 349 0.142
response to wounding GO:0009611 254 0.139
positive regulation of biosynthetic process GO:0009891 319 0.126
regulation of system process GO:0044057 208 0.122
mapk cascade GO:0000165 140 0.118
response to metal ion GO:0010038 253 0.115
apoptotic process GO:0006915 381 0.113
metal ion transport GO:0030001 289 0.102
programmed cell death GO:0012501 392 0.099
calcium ion homeostasis GO:0055074 162 0.099
regulation of cellular localization GO:0060341 263 0.098
transcription dna templated GO:0006351 377 0.098
response to radiation GO:0009314 137 0.096
cellular calcium ion homeostasis GO:0006874 160 0.091
regulation of programmed cell death GO:0043067 341 0.090
regulation of secretion by cell GO:1903530 208 0.090
cellular amine metabolic process GO:0044106 38 0.089
defense response GO:0006952 194 0.089
circulatory system process GO:0003013 183 0.089
response to peptide hormone GO:0043434 278 0.087
protein phosphorylation GO:0006468 345 0.087
regulation of phosphorus metabolic process GO:0051174 349 0.086
cellular response to nitrogen compound GO:1901699 210 0.084
cellular component movement GO:0006928 248 0.084
regulation of calcium ion transport GO:0051924 77 0.084
inorganic cation transmembrane transport GO:0098662 202 0.084
regulation of phosphorylation GO:0042325 248 0.082
positive regulation of cell death GO:0010942 184 0.082
amine metabolic process GO:0009308 38 0.080
cellular amino acid metabolic process GO:0006520 107 0.079
reproductive process GO:0022414 372 0.079
positive regulation of cell communication GO:0010647 271 0.078
positive regulation of response to stimulus GO:0048584 285 0.078
single organism intracellular transport GO:1902582 166 0.078
regulation of secretion GO:0051046 224 0.077
regulation of molecular function GO:0065009 398 0.075
negative regulation of multicellular organismal process GO:0051241 203 0.073
positive regulation of signaling GO:0023056 270 0.072
neurological system process GO:0050877 219 0.072
calcium ion transmembrane transport GO:0070588 70 0.071
response to cytokine GO:0034097 215 0.070
regulation of protein phosphorylation GO:0001932 183 0.070
regulation of apoptotic process GO:0042981 335 0.069
positive regulation of intracellular signal transduction GO:1902533 138 0.069
response to extracellular stimulus GO:0009991 380 0.068
response to corticosteroid GO:0031960 235 0.067
regulation of protein metabolic process GO:0051246 289 0.067
sensory perception of pain GO:0019233 73 0.064
cellular response to tumor necrosis factor GO:0071356 46 0.064
oxoacid metabolic process GO:0043436 290 0.063
positive regulation of mapk cascade GO:0043410 92 0.062
tissue development GO:0009888 252 0.062
regulation of blood pressure GO:0008217 83 0.062
regulation of membrane potential GO:0042391 110 0.060
cellular divalent inorganic cation homeostasis GO:0072503 162 0.060
regulation of cell proliferation GO:0042127 359 0.060
regulation of mapk cascade GO:0043408 116 0.059
chemical homeostasis GO:0048878 292 0.059
negative regulation of biosynthetic process GO:0009890 168 0.059
carboxylic acid metabolic process GO:0019752 289 0.058
regulation of metal ion transport GO:0010959 118 0.058
positive regulation of signal transduction GO:0009967 175 0.058
positive regulation of multicellular organismal process GO:0051240 387 0.057
g protein coupled receptor signaling pathway GO:0007186 242 0.057
cellular metal ion homeostasis GO:0006875 172 0.056
immune system process GO:0002376 204 0.056
positive regulation of protein modification process GO:0031401 142 0.056
cation transport GO:0006812 382 0.056
response to nutrient GO:0007584 248 0.056
positive regulation of phosphorylation GO:0042327 177 0.055
small molecule biosynthetic process GO:0044283 124 0.055
organic acid metabolic process GO:0006082 292 0.054
cellular chemical homeostasis GO:0055082 247 0.053
rna metabolic process GO:0016070 406 0.053
stress activated protein kinase signaling cascade GO:0031098 37 0.053
smooth muscle cell proliferation GO:0048659 77 0.053
nucleobase containing small molecule metabolic process GO:0055086 316 0.052
regulation of cellular amine metabolic process GO:0033238 8 0.052
positive regulation of protein phosphorylation GO:0001934 135 0.052
regulation of cellular ketone metabolic process GO:0010565 27 0.051
positive regulation of programmed cell death GO:0043068 157 0.050
cellular homeostasis GO:0019725 252 0.050
head development GO:0060322 247 0.050
blood circulation GO:0008015 183 0.050
positive regulation of apoptotic process GO:0043065 154 0.050
anatomical structure morphogenesis GO:0009653 298 0.049
cytosolic calcium ion homeostasis GO:0051480 140 0.049
positive regulation of molecular function GO:0044093 230 0.049
response to nutrient levels GO:0031667 370 0.048
locomotion GO:0040011 237 0.047
ion transmembrane transport GO:0034220 365 0.047
central nervous system development GO:0007417 311 0.047
cation homeostasis GO:0055080 195 0.047
regulation of catalytic activity GO:0050790 304 0.046
positive regulation of phosphorus metabolic process GO:0010562 262 0.046
cellular ketone metabolic process GO:0042180 51 0.045
divalent metal ion transport GO:0070838 132 0.044
inflammatory response GO:0006954 150 0.044
response to mineralocorticoid GO:0051385 49 0.044
positive regulation of locomotion GO:0040017 102 0.044
cell projection organization GO:0030030 302 0.044
regulation of cellular amino acid metabolic process GO:0006521 2 0.043
regulation of cellular protein metabolic process GO:0032268 267 0.043
cation transmembrane transport GO:0098655 263 0.042
monovalent inorganic cation transport GO:0015672 172 0.041
secretion GO:0046903 307 0.040
single organism biosynthetic process GO:0044711 342 0.040
cellular cation homeostasis GO:0030003 180 0.040
protein localization GO:0008104 191 0.039
sensory perception GO:0007600 101 0.039
regulation of transcription dna templated GO:0006355 374 0.039
cellular response to organic cyclic compound GO:0071407 202 0.039
nucleic acid templated transcription GO:0097659 379 0.039
cellular response to cytokine stimulus GO:0071345 127 0.039
divalent inorganic cation homeostasis GO:0072507 165 0.039
cellular ion homeostasis GO:0006873 184 0.039
divalent inorganic cation transport GO:0072511 134 0.038
regulation of response to stress GO:0080134 126 0.038
regulation of homeostatic process GO:0032844 101 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
macromolecule localization GO:0033036 252 0.037
renal system process GO:0003014 40 0.037
response to ketone GO:1901654 182 0.037
regulation of blood circulation GO:1903522 110 0.037
response to alkaloid GO:0043279 132 0.036
proteolysis GO:0006508 175 0.036
regulation of cell development GO:0060284 263 0.036
response to hypoxia GO:0001666 231 0.036
intracellular transport GO:0046907 185 0.035
neuron differentiation GO:0030182 368 0.035
response to inorganic substance GO:0010035 377 0.035
positive regulation of catalytic activity GO:0043085 184 0.035
brain development GO:0007420 247 0.035
calcium ion transport GO:0006816 131 0.035
regulation of ion transport GO:0043269 245 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
single organism catabolic process GO:0044712 283 0.034
response to tumor necrosis factor GO:0034612 56 0.034
vascular process in circulatory system GO:0003018 96 0.034
establishment of protein localization GO:0045184 141 0.033
cellular macromolecule localization GO:0070727 122 0.033
response to estradiol GO:0032355 164 0.033
regulation of protein transport GO:0051223 68 0.033
wound healing GO:0042060 122 0.032
neuron development GO:0048666 286 0.032
regulation of intracellular signal transduction GO:1902531 218 0.032
localization of cell GO:0051674 202 0.031
response to axon injury GO:0048678 59 0.031
rna biosynthetic process GO:0032774 380 0.031
regulation of cellular component organization GO:0051128 368 0.031
response to decreased oxygen levels GO:0036293 237 0.030
single organism reproductive process GO:0044702 297 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.030
positive regulation of cellular amine metabolic process GO:0033240 3 0.029
heart contraction GO:0060047 57 0.029
regulation of rna biosynthetic process GO:2001141 381 0.029
metal ion homeostasis GO:0055065 186 0.029
regulation of muscle system process GO:0090257 79 0.029
negative regulation of metabolic process GO:0009892 331 0.029
regulation of heart contraction GO:0008016 48 0.029
regulation of rna metabolic process GO:0051252 391 0.029
positive regulation of secretion GO:0051047 140 0.028
positive regulation of brown fat cell proliferation GO:0070349 1 0.028
organic substance catabolic process GO:1901575 316 0.028
inorganic ion transmembrane transport GO:0098660 229 0.028
alcohol metabolic process GO:0006066 77 0.027
regulation of signal transduction GO:0009966 318 0.027
ribose phosphate metabolic process GO:0019693 235 0.027
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.027
cell cell signaling GO:0007267 335 0.027
positive regulation of gene expression GO:0010628 244 0.027
regulation of cell differentiation GO:0045595 320 0.026
cellular response to stress GO:0033554 269 0.026
regulation of blood vessel size GO:0050880 89 0.026
positive regulation of blood circulation GO:1903524 65 0.026
transmembrane transport GO:0055085 412 0.026
eye morphogenesis GO:0048592 4 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
negative regulation of transport GO:0051051 136 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
heart process GO:0003015 57 0.025
potassium ion transport GO:0006813 97 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
regulation of cation channel activity GO:2001257 23 0.025
cellular lipid metabolic process GO:0044255 208 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
behavior GO:0007610 205 0.025
stress activated mapk cascade GO:0051403 35 0.024
development of primary female sexual characteristics GO:0046545 56 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
regulation of anatomical structure size GO:0090066 135 0.024
multicellular organism reproduction GO:0032504 233 0.024
response to activity GO:0014823 73 0.024
negative regulation of ion transport GO:0043271 51 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
response to estrogen GO:0043627 232 0.023
ion homeostasis GO:0050801 212 0.023
camera type eye morphogenesis GO:0048593 2 0.022
cell activation GO:0001775 97 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
purine containing compound metabolic process GO:0072521 253 0.022
positive regulation of cell development GO:0010720 176 0.022
muscle system process GO:0003012 115 0.022
circulatory system development GO:0072359 134 0.022
neuron projection development GO:0031175 273 0.021
negative regulation of cell death GO:0060548 229 0.021
response to hexose GO:0009746 144 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
muscle contraction GO:0006936 88 0.021
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
lipid biosynthetic process GO:0008610 128 0.020
development of primary sexual characteristics GO:0045137 107 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
response to ethanol GO:0045471 162 0.020
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.020
muscle cell proliferation GO:0033002 84 0.020
second messenger mediated signaling GO:0019932 51 0.020
macromolecular complex assembly GO:0065003 273 0.020
positive regulation of secretion by cell GO:1903532 128 0.020
response to monosaccharide GO:0034284 159 0.020
gonad development GO:0008406 104 0.020
cytokine production GO:0001816 61 0.019
erk1 and erk2 cascade GO:0070371 48 0.019
response to cadmium ion GO:0046686 35 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
regulation of neuron apoptotic process GO:0043523 83 0.019
cellular component biogenesis GO:0044085 368 0.019
nucleotide metabolic process GO:0009117 279 0.019
positive regulation of transport GO:0051050 245 0.019
negative regulation of protein metabolic process GO:0051248 114 0.019
regulation of transporter activity GO:0032409 50 0.018
response to glucose GO:0009749 136 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
response to bacterium GO:0009617 200 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
positive regulation of nervous system development GO:0051962 178 0.018
response to temperature stimulus GO:0009266 94 0.018
organelle organization GO:0006996 266 0.018
cytoplasmic transport GO:0016482 115 0.018
growth GO:0040007 165 0.018
catabolic process GO:0009056 351 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
negative regulation of gene expression GO:0010629 199 0.018
positive regulation of synaptic plasticity GO:0031915 3 0.018
cardiovascular system development GO:0072358 134 0.018
response to growth factor GO:0070848 189 0.018
response to antibiotic GO:0046677 39 0.018
epithelial cell differentiation GO:0030855 71 0.018
single organism cellular localization GO:1902580 102 0.018
regulation of nucleic acid templated transcription GO:1903506 380 0.017
response to light stimulus GO:0009416 52 0.017
purine containing compound biosynthetic process GO:0072522 85 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
negative regulation of secretion GO:0051048 82 0.017
regulation of hydrolase activity GO:0051336 143 0.017
ras protein signal transduction GO:0007265 29 0.017
positive regulation of ion transport GO:0043270 94 0.017
protein transport GO:0015031 132 0.017
reproductive structure development GO:0048608 128 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
regulation of reactive oxygen species metabolic process GO:2000377 26 0.017
multi organism reproductive process GO:0044703 262 0.017
cellular response to hormone stimulus GO:0032870 247 0.016
response to reactive oxygen species GO:0000302 120 0.016
regulation of immune system process GO:0002682 123 0.016
cellular response to lipid GO:0071396 201 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
organophosphate metabolic process GO:0019637 370 0.016
response to corticosterone GO:0051412 40 0.016
actin filament based process GO:0030029 86 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
secretion by cell GO:0032940 248 0.016
regulation of protein kinase activity GO:0045859 105 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
regulation of hormone levels GO:0010817 187 0.016
regulation of synaptic transmission GO:0050804 141 0.016
gamete generation GO:0007276 124 0.016
cyclic nucleotide biosynthetic process GO:0009190 63 0.016
response to calcium ion GO:0051592 59 0.016
negative regulation of molecular function GO:0044092 133 0.016
axonogenesis GO:0007409 71 0.016
action potential GO:0001508 54 0.015
regulation of proteolysis GO:0030162 66 0.015
acute inflammatory response GO:0002526 58 0.015
single organism behavior GO:0044708 130 0.015
regulation of ion transmembrane transport GO:0034765 121 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
developmental growth GO:0048589 100 0.015
multicellular organismal signaling GO:0035637 44 0.015
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.014
nerve development GO:0021675 11 0.014
regulation of transferase activity GO:0051338 123 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
phospholipid metabolic process GO:0006644 61 0.014
cellular response to biotic stimulus GO:0071216 59 0.014
regulation of nervous system development GO:0051960 264 0.014
intracellular protein transport GO:0006886 79 0.014
cellular component assembly GO:0022607 360 0.014
lipid metabolic process GO:0006629 283 0.014
membrane organization GO:0061024 94 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
reactive oxygen species metabolic process GO:0072593 37 0.014
cellular potassium ion transport GO:0071804 72 0.014
response to peptide GO:1901652 292 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
endocrine process GO:0050886 32 0.014
cellular response to metal ion GO:0071248 55 0.014
cell migration GO:0016477 197 0.013
camera type eye development GO:0043010 48 0.013
regulation of erk1 and erk2 cascade GO:0070372 41 0.013
chemotaxis GO:0006935 66 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
regulation of transmembrane transport GO:0034762 122 0.013
ovulation cycle GO:0042698 67 0.013
regulation of protein modification process GO:0031399 194 0.013
cellular response to alkaloid GO:0071312 25 0.013
cardiac muscle contraction GO:0060048 27 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
fat cell proliferation GO:0070341 2 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
regulation of hormone secretion GO:0046883 106 0.013
excretion GO:0007588 24 0.013
response to heat GO:0009408 60 0.013
potassium ion transmembrane transport GO:0071805 71 0.013
nitrogen compound transport GO:0071705 229 0.013
protein polymerization GO:0051258 22 0.013
positive regulation of developmental process GO:0051094 283 0.013
male sex differentiation GO:0046661 64 0.013
regulation of systemic arterial blood pressure GO:0003073 30 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
leukocyte activation GO:0045321 76 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
protein complex subunit organization GO:0071822 302 0.013
regulation of neurogenesis GO:0050767 247 0.013
forebrain development GO:0030900 98 0.013
response to oxidative stress GO:0006979 186 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
epithelial cell proliferation GO:0050673 54 0.013
negative regulation of signaling GO:0023057 157 0.013
response to purine containing compound GO:0014074 126 0.013
regulation of cytokine production GO:0001817 56 0.013
activation of protein kinase activity GO:0032147 47 0.013
regulation of body fluid levels GO:0050878 90 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
regulation of cell projection organization GO:0031344 175 0.013
sodium ion transport GO:0006814 82 0.013
regulation of synaptic plasticity GO:0048167 70 0.012
positive regulation of defense response GO:0031349 37 0.012
positive regulation of calcium ion transport GO:0051928 36 0.012
isoprenoid metabolic process GO:0006720 45 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
retina morphogenesis in camera type eye GO:0060042 1 0.012
ossification GO:0001503 70 0.012
cognition GO:0050890 92 0.012
learning or memory GO:0007611 90 0.012
vasoconstriction GO:0042310 54 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
neuromuscular process GO:0050905 2 0.012
positive regulation of cytoskeleton organization GO:0051495 26 0.012
negative regulation of cell communication GO:0010648 158 0.012
response to vitamin GO:0033273 131 0.012
spermatogenesis GO:0007283 99 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
response to oxygen levels GO:0070482 265 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
rhythmic process GO:0048511 156 0.012
regulation of endocrine process GO:0044060 21 0.012
regulation of neuron projection development GO:0010975 161 0.012
multicellular organismal homeostasis GO:0048871 49 0.011
response to mechanical stimulus GO:0009612 134 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
positive regulation of transmembrane transport GO:0034764 25 0.011
response to fatty acid GO:0070542 65 0.011
micturition GO:0060073 4 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
protein maturation GO:0051604 68 0.011
epithelium development GO:0060429 96 0.011
regulation of ion transmembrane transporter activity GO:0032412 48 0.011
regulation of vasoconstriction GO:0019229 44 0.011
developmental process involved in reproduction GO:0003006 159 0.011
telencephalon development GO:0021537 62 0.011
response to amino acid GO:0043200 75 0.011
regulation of inflammatory response GO:0050727 48 0.011
regulation of defense response GO:0031347 68 0.011
myeloid leukocyte activation GO:0002274 36 0.011
response to acid chemical GO:0001101 222 0.011
response to external biotic stimulus GO:0043207 221 0.011
ovulation cycle process GO:0022602 50 0.011
protein localization to organelle GO:0033365 57 0.011
hormone secretion GO:0046879 115 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
regulation of cellular component movement GO:0051270 150 0.011
immune response GO:0006955 104 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
regulation of response to external stimulus GO:0032101 106 0.011
regulation of neuron death GO:1901214 115 0.010
regulation of protein localization GO:0032880 81 0.010
negative regulation of protein maturation GO:1903318 47 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
male gamete generation GO:0048232 99 0.010
positive regulation of protein kinase activity GO:0045860 73 0.010
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
synaptic transmission GO:0007268 235 0.010
negative regulation of catalytic activity GO:0043086 103 0.010

Nox1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
disease of cellular proliferation DOID:14566 0 0.010