Rattus norvegicus

18 known processes

Sds

serine dehydratase

(Aliases: RATSDHE1,TDH,Sdh,SDH2,Sdhe1,MGC108581)

Sds biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
alpha amino acid metabolic process GO:1901605 71 0.649
organic acid metabolic process GO:0006082 292 0.495
carboxylic acid metabolic process GO:0019752 289 0.353
cellular amino acid biosynthetic process GO:0008652 32 0.337
oxoacid metabolic process GO:0043436 290 0.320
organic acid biosynthetic process GO:0016053 83 0.292
carboxylic acid biosynthetic process GO:0046394 83 0.269
alpha amino acid biosynthetic process GO:1901607 23 0.196
response to inorganic substance GO:0010035 377 0.177
lipid metabolic process GO:0006629 283 0.146
cellular amino acid metabolic process GO:0006520 107 0.141
monocarboxylic acid metabolic process GO:0032787 152 0.138
small molecule biosynthetic process GO:0044283 124 0.130
signal release GO:0023061 145 0.128
cellular catabolic process GO:0044248 295 0.125
cell motility GO:0048870 202 0.102
nitrogen compound transport GO:0071705 229 0.096
regulation of rna biosynthetic process GO:2001141 381 0.096
cell cell signaling GO:0007267 335 0.094
localization of cell GO:0051674 202 0.087
single organism biosynthetic process GO:0044711 342 0.077
organic substance catabolic process GO:1901575 316 0.077
cellular component movement GO:0006928 248 0.077
response to corticosteroid GO:0031960 235 0.073
regulation of cellular component movement GO:0051270 150 0.073
regulation of multicellular organismal development GO:2000026 376 0.067
response to acid chemical GO:0001101 222 0.067
response to extracellular stimulus GO:0009991 380 0.067
regulation of cell motility GO:2000145 131 0.066
regeneration GO:0031099 163 0.061
catabolic process GO:0009056 351 0.059
cellular lipid metabolic process GO:0044255 208 0.057
cellular response to hormone stimulus GO:0032870 247 0.055
cellular component assembly GO:0022607 360 0.055
multicellular organism reproduction GO:0032504 233 0.047
chemical homeostasis GO:0048878 292 0.046
regulation of hormone levels GO:0010817 187 0.044
positive regulation of developmental process GO:0051094 283 0.043
response to peptide hormone GO:0043434 278 0.043
cellular response to oxygen containing compound GO:1901701 386 0.042
regulation of peptide transport GO:0090087 87 0.042
single organism catabolic process GO:0044712 283 0.041
cell migration GO:0016477 197 0.041
response to ketone GO:1901654 182 0.041
regulation of insulin secretion GO:0050796 65 0.041
cellular modified amino acid metabolic process GO:0006575 61 0.040
gamete generation GO:0007276 124 0.040
synaptic transmission GO:0007268 235 0.040
regulation of rna metabolic process GO:0051252 391 0.040
multicellular organismal reproductive process GO:0048609 233 0.040
ion homeostasis GO:0050801 212 0.040
head development GO:0060322 247 0.039
cellular response to lipid GO:0071396 201 0.039
lipid biosynthetic process GO:0008610 128 0.039
response to oxidative stress GO:0006979 186 0.038
small molecule catabolic process GO:0044282 59 0.038
sexual reproduction GO:0019953 148 0.038
carbohydrate derivative metabolic process GO:1901135 346 0.037
central nervous system development GO:0007417 311 0.036
cell projection organization GO:0030030 302 0.036
transcription from rna polymerase ii promoter GO:0006366 252 0.035
regulation of molecular function GO:0065009 398 0.035
locomotion GO:0040011 237 0.035
cellular response to growth factor stimulus GO:0071363 162 0.034
cellular response to organic cyclic compound GO:0071407 202 0.034
neuron differentiation GO:0030182 368 0.033
regulation of peptide hormone secretion GO:0090276 80 0.033
protein homooligomerization GO:0051260 91 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.032
gonad development GO:0008406 104 0.032
peptide hormone secretion GO:0030072 84 0.032
secretion GO:0046903 307 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.032
negative regulation of nervous system development GO:0051961 79 0.032
anion transmembrane transport GO:0098656 77 0.032
cellular response to alcohol GO:0097306 87 0.032
organic hydroxy compound metabolic process GO:1901615 115 0.032
cellular component biogenesis GO:0044085 368 0.031
g protein coupled receptor signaling pathway GO:0007186 242 0.031
hormone transport GO:0009914 121 0.031
regulation of system process GO:0044057 208 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
insulin secretion GO:0030073 69 0.031
sterol catabolic process GO:0016127 1 0.031
reproduction GO:0000003 245 0.030
peptide secretion GO:0002790 86 0.030
cellular response to endogenous stimulus GO:0071495 377 0.030
cellular response to peptide GO:1901653 133 0.030
organic acid catabolic process GO:0016054 49 0.029
macromolecular complex subunit organization GO:0043933 339 0.029
alpha amino acid catabolic process GO:1901606 20 0.029
regulation of peptide secretion GO:0002791 82 0.028
positive regulation of transcription dna templated GO:0045893 197 0.028
protein complex assembly GO:0006461 263 0.028
cellular ketone metabolic process GO:0042180 51 0.028
peptide transport GO:0015833 97 0.028
cellular chemical homeostasis GO:0055082 247 0.027
protein oligomerization GO:0051259 191 0.027
cellular response to nitrogen compound GO:1901699 210 0.027
regulation of cell migration GO:0030334 128 0.027
behavior GO:0007610 205 0.027
secretion by cell GO:0032940 248 0.027
protein phosphorylation GO:0006468 345 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
developmental process involved in reproduction GO:0003006 159 0.026
metal ion homeostasis GO:0055065 186 0.026
purine containing compound metabolic process GO:0072521 253 0.026
inflammatory response GO:0006954 150 0.026
regulation of hormone secretion GO:0046883 106 0.026
fatty acid metabolic process GO:0006631 99 0.026
serine family amino acid metabolic process GO:0009069 12 0.026
regulation of secretion by cell GO:1903530 208 0.026
blood circulation GO:0008015 183 0.026
anatomical structure morphogenesis GO:0009653 298 0.026
protein complex biogenesis GO:0070271 263 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
positive regulation of rna metabolic process GO:0051254 203 0.025
tissue development GO:0009888 252 0.025
single organism carbohydrate metabolic process GO:0044723 118 0.024
positive regulation of protein phosphorylation GO:0001934 135 0.024
multi organism reproductive process GO:0044703 262 0.024
aging GO:0007568 241 0.024
amide transport GO:0042886 105 0.024
cell morphogenesis involved in differentiation GO:0000904 119 0.024
homeostatic process GO:0042592 331 0.024
response to peptide GO:1901652 292 0.024
glycosyl compound metabolic process GO:1901657 182 0.024
glycerolipid metabolic process GO:0046486 67 0.023
actin filament based process GO:0030029 86 0.023
regulation of cell differentiation GO:0045595 320 0.023
regulation of protein metabolic process GO:0051246 289 0.022
epithelium development GO:0060429 96 0.022
spermatogenesis GO:0007283 99 0.022
sensory organ development GO:0007423 74 0.022
positive regulation of peptide secretion GO:0002793 52 0.022
amine metabolic process GO:0009308 38 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
metanephric s shaped body morphogenesis GO:0072284 2 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
response to food GO:0032094 27 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
fatty acid transport GO:0015908 25 0.021
positive regulation of signaling GO:0023056 270 0.020
response to cytokine GO:0034097 215 0.020
immune system process GO:0002376 204 0.020
response to vitamin GO:0033273 131 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
reproductive process GO:0022414 372 0.020
cellular response to glucocorticoid stimulus GO:0071385 68 0.020
response to monosaccharide GO:0034284 159 0.019
cellular homeostasis GO:0019725 252 0.019
ion transmembrane transport GO:0034220 365 0.019
organ morphogenesis GO:0009887 75 0.019
negative regulation of signaling GO:0023057 157 0.019
neuron development GO:0048666 286 0.019
rna biosynthetic process GO:0032774 380 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.018
regulation of secretion GO:0051046 224 0.018
lipid catabolic process GO:0016042 46 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
positive regulation of cell development GO:0010720 176 0.017
nucleoside metabolic process GO:0009116 179 0.017
positive regulation of peptide hormone secretion GO:0090277 50 0.017
divalent metal ion transport GO:0070838 132 0.017
response to glucocorticoid GO:0051384 223 0.017
single organism reproductive process GO:0044702 297 0.017
cellular amine metabolic process GO:0044106 38 0.017
serine family amino acid biosynthetic process GO:0009070 4 0.017
negative regulation of cell development GO:0010721 82 0.017
reproductive structure development GO:0048608 128 0.017
neurological system process GO:0050877 219 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
glutamine family amino acid metabolic process GO:0009064 15 0.017
regulation of nervous system development GO:0051960 264 0.017
cellular amino acid catabolic process GO:0009063 21 0.016
protein tetramerization GO:0051262 38 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
response to metal ion GO:0010038 253 0.016
regulation of catabolic process GO:0009894 113 0.016
transcription dna templated GO:0006351 377 0.016
response to nutrient levels GO:0031667 370 0.016
organ regeneration GO:0031100 101 0.016
response to glucose GO:0009749 136 0.016
digestive system development GO:0055123 41 0.015
single organism organelle organization GO:1902589 180 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
hepaticobiliary system development GO:0061008 90 0.015
oxidation reduction process GO:0055114 304 0.015
steroid catabolic process GO:0006706 5 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
hormone secretion GO:0046879 115 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
macromolecular complex assembly GO:0065003 273 0.015
mechanoreceptor differentiation GO:0042490 2 0.015
circulatory system process GO:0003013 183 0.015
jnk cascade GO:0007254 28 0.015
bile acid biosynthetic process GO:0006699 3 0.015
retina morphogenesis in camera type eye GO:0060042 1 0.015
regulation of programmed cell death GO:0043067 341 0.015
protein complex subunit organization GO:0071822 302 0.014
regulation of transcription dna templated GO:0006355 374 0.014
nucleic acid templated transcription GO:0097659 379 0.014
neuron projection development GO:0031175 273 0.014
defense response GO:0006952 194 0.014
organic hydroxy compound biosynthetic process GO:1901617 51 0.014
male gamete generation GO:0048232 99 0.014
regulation of leukocyte differentiation GO:1902105 20 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
regulation of cellular localization GO:0060341 263 0.014
positive regulation of protein modification process GO:0031401 142 0.014
response to xenobiotic stimulus GO:0009410 23 0.014
response to ammonium ion GO:0060359 71 0.014
calcium ion homeostasis GO:0055074 162 0.014
reactive nitrogen species metabolic process GO:2001057 1 0.014
intracellular receptor signaling pathway GO:0030522 35 0.014
sulfur compound metabolic process GO:0006790 70 0.014
cellular response to corticosteroid stimulus GO:0071384 69 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
programmed cell death GO:0012501 392 0.013
lipid storage GO:0019915 1 0.013
nucleotide metabolic process GO:0009117 279 0.013
gastrulation GO:0007369 2 0.013
growth GO:0040007 165 0.013
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.013
fertilization GO:0009566 3 0.013
negative regulation of neurogenesis GO:0050768 78 0.013
development of primary male sexual characteristics GO:0046546 59 0.013
adult locomotory behavior GO:0008344 4 0.013
negative regulation of neuron differentiation GO:0045665 62 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
cerebellar granule cell precursor proliferation GO:0021930 1 0.013
cellular ion homeostasis GO:0006873 184 0.013
regulation of catalytic activity GO:0050790 304 0.013
regulation of dendrite development GO:0050773 59 0.012
negative regulation of growth GO:0045926 37 0.012
regulation of blood pressure GO:0008217 83 0.012
chlorinated hydrocarbon metabolic process GO:0042196 4 0.012
regulation of cell development GO:0060284 263 0.012
multicellular organism growth GO:0035264 1 0.012
monosaccharide metabolic process GO:0005996 61 0.012
sensory perception GO:0007600 101 0.012
single organism behavior GO:0044708 130 0.012
heterocycle catabolic process GO:0046700 167 0.012
brain development GO:0007420 247 0.012
aromatic compound catabolic process GO:0019439 168 0.012
action potential GO:0001508 54 0.012
regulation of ion transport GO:0043269 245 0.012
negative regulation of metabolic process GO:0009892 331 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
transmembrane transport GO:0055085 412 0.012
negative regulation of cell death GO:0060548 229 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
carboxylic acid catabolic process GO:0046395 49 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
linoleic acid metabolic process GO:0043651 4 0.011
cation homeostasis GO:0055080 195 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
response to prostaglandin f GO:0034696 4 0.011
organophosphate metabolic process GO:0019637 370 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
positive regulation of molecular function GO:0044093 230 0.011
regulation of cellular component organization GO:0051128 368 0.011
regulation of appetite GO:0032098 8 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
regulation of signal transduction GO:0009966 318 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
carbohydrate metabolic process GO:0005975 130 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
maintenance of location GO:0051235 17 0.011
positive regulation of biosynthetic process GO:0009891 319 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
cellular response to tumor necrosis factor GO:0071356 46 0.011
rna metabolic process GO:0016070 406 0.011
response to ethanol GO:0045471 162 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
regulation of neurogenesis GO:0050767 247 0.011
regulation of protein serine threonine kinase activity GO:0071900 64 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
lipid transport GO:0006869 61 0.011
response to estrogen GO:0043627 232 0.010
glycine metabolic process GO:0006544 7 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
positive regulation of response to stimulus GO:0048584 285 0.010
positive regulation of cellular biosynthetic process GO:0031328 295 0.010
calcium ion transport GO:0006816 131 0.010
positive regulation of transport GO:0051050 245 0.010
response to transforming growth factor beta GO:0071559 46 0.010
male sex differentiation GO:0046661 64 0.010
negative regulation of intracellular estrogen receptor signaling pathway GO:0033147 2 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
cellular cation homeostasis GO:0030003 180 0.010
negative regulation of response to extracellular stimulus GO:0032105 7 0.010

Sds disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.052
inherited metabolic disorder DOID:655 0 0.052
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
organ system cancer DOID:0050686 0 0.016