Rattus norvegicus

0 known processes

Gak

cyclin G associated kinase

Gak biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism catabolic process GO:0044712 283 0.157
purine nucleoside metabolic process GO:0042278 169 0.150
anatomical structure morphogenesis GO:0009653 298 0.147
Mouse Fly
reproductive process GO:0022414 372 0.139
Fly
catabolic process GO:0009056 351 0.135
reproduction GO:0000003 245 0.120
Fly
nucleobase containing small molecule metabolic process GO:0055086 316 0.115
organonitrogen compound catabolic process GO:1901565 179 0.105
cell cell signaling GO:0007267 335 0.101
cellular catabolic process GO:0044248 295 0.099
organic substance catabolic process GO:1901575 316 0.098
cellular component biogenesis GO:0044085 368 0.097
macromolecular complex subunit organization GO:0043933 339 0.095
Mouse
apoptotic process GO:0006915 381 0.093
nucleotide metabolic process GO:0009117 279 0.091
regulation of cellular component organization GO:0051128 368 0.085
macromolecular complex assembly GO:0065003 273 0.085
vesicle mediated transport GO:0016192 181 0.078
Mouse
organophosphate metabolic process GO:0019637 370 0.075
carboxylic acid metabolic process GO:0019752 289 0.070
glycosyl compound metabolic process GO:1901657 182 0.068
nucleoside phosphate metabolic process GO:0006753 283 0.067
carbohydrate derivative metabolic process GO:1901135 346 0.064
gland development GO:0048732 155 0.060
Mouse
purine ribonucleotide metabolic process GO:0009150 227 0.059
multicellular organism reproduction GO:0032504 233 0.056
Fly
purine nucleoside triphosphate catabolic process GO:0009146 122 0.055
macromolecule localization GO:0033036 252 0.055
organelle organization GO:0006996 266 0.053
Mouse
oxoacid metabolic process GO:0043436 290 0.053
developmental process involved in reproduction GO:0003006 159 0.052
Fly
purine nucleoside triphosphate metabolic process GO:0009144 141 0.051
ribose phosphate metabolic process GO:0019693 235 0.049
metal ion transport GO:0030001 289 0.048
programmed cell death GO:0012501 392 0.048
nucleoside triphosphate metabolic process GO:0009141 144 0.048
regulation of apoptotic process GO:0042981 335 0.047
secretion by cell GO:0032940 248 0.046
purine nucleotide metabolic process GO:0006163 229 0.045
ribonucleotide metabolic process GO:0009259 231 0.045
protein complex biogenesis GO:0070271 263 0.044
cellular component assembly GO:0022607 360 0.043
receptor internalization GO:0031623 14 0.043
membrane organization GO:0061024 94 0.043
regulation of cell differentiation GO:0045595 320 0.042
transcription from rna polymerase ii promoter GO:0006366 252 0.042
synaptic vesicle endocytosis GO:0048488 4 0.040
regulation of molecular function GO:0065009 398 0.040
multicellular organismal reproductive process GO:0048609 233 0.040
Fly
cation transmembrane transport GO:0098655 263 0.039
regulation of anatomical structure morphogenesis GO:0022603 141 0.039
regulation of cellular localization GO:0060341 263 0.038
protein homooligomerization GO:0051260 91 0.038
response to metal ion GO:0010038 253 0.038
regulation of multicellular organismal development GO:2000026 376 0.037
transmembrane transport GO:0055085 412 0.037
response to nutrient levels GO:0031667 370 0.037
receptor mediated endocytosis GO:0006898 42 0.036
Mouse
response to inorganic substance GO:0010035 377 0.036
cation transport GO:0006812 382 0.036
secretion GO:0046903 307 0.036
multi organism reproductive process GO:0044703 262 0.036
Fly
hepaticobiliary system development GO:0061008 90 0.035
Mouse
ribonucleoside metabolic process GO:0009119 174 0.035
nucleoside catabolic process GO:0009164 126 0.034
neuron differentiation GO:0030182 368 0.034
cellular lipid metabolic process GO:0044255 208 0.034
ribonucleoside triphosphate catabolic process GO:0009203 122 0.033
response to nutrient GO:0007584 248 0.033
regulation of secretion GO:0051046 224 0.033
ribonucleotide catabolic process GO:0009261 136 0.032
purine ribonucleoside catabolic process GO:0046130 124 0.032
gamete generation GO:0007276 124 0.032
Fly
actin filament based process GO:0030029 86 0.032
purine nucleotide catabolic process GO:0006195 136 0.032
cellular nitrogen compound catabolic process GO:0044270 163 0.031
protein oligomerization GO:0051259 191 0.031
cation homeostasis GO:0055080 195 0.031
negative regulation of cell communication GO:0010648 158 0.031
lipid metabolic process GO:0006629 283 0.030
single organism reproductive process GO:0044702 297 0.030
Fly
aromatic compound catabolic process GO:0019439 168 0.030
single organism biosynthetic process GO:0044711 342 0.030
regulation of neurogenesis GO:0050767 247 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.029
purine containing compound metabolic process GO:0072521 253 0.029
central nervous system development GO:0007417 311 0.029
Mouse
endocytosis GO:0006897 84 0.029
Mouse
nucleoside phosphate catabolic process GO:1901292 140 0.029
actin cytoskeleton organization GO:0030036 73 0.028
nucleotide catabolic process GO:0009166 139 0.028
response to acid chemical GO:0001101 222 0.028
negative regulation of cellular component organization GO:0051129 83 0.028
cell projection organization GO:0030030 302 0.028
single organism membrane organization GO:0044802 74 0.027
regulation of anatomical structure size GO:0090066 135 0.027
ras protein signal transduction GO:0007265 29 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
endomembrane system organization GO:0010256 48 0.027
Mouse
nucleobase containing compound catabolic process GO:0034655 152 0.027
protein complex subunit organization GO:0071822 302 0.027
Mouse
organic cyclic compound catabolic process GO:1901361 175 0.026
cell motility GO:0048870 202 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
cellular component movement GO:0006928 248 0.026
ribonucleoside catabolic process GO:0042454 126 0.026
organic acid metabolic process GO:0006082 292 0.026
cellular amine metabolic process GO:0044106 38 0.026
cellular amide metabolic process GO:0043603 44 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
establishment of organelle localization GO:0051656 37 0.026
response to peptide hormone GO:0043434 278 0.026
nucleoside metabolic process GO:0009116 179 0.025
small molecule biosynthetic process GO:0044283 124 0.025
response to oxidative stress GO:0006979 186 0.025
ion homeostasis GO:0050801 212 0.025
regulation of system process GO:0044057 208 0.025
salivary gland morphogenesis GO:0007435 1 0.025
vesicle organization GO:0016050 29 0.024
glycosyl compound catabolic process GO:1901658 126 0.024
synaptic transmission GO:0007268 235 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
organophosphate catabolic process GO:0046434 148 0.024
cell cycle GO:0007049 101 0.024
cytoskeleton organization GO:0007010 111 0.024
brain development GO:0007420 247 0.023
Mouse
proteolysis GO:0006508 175 0.023
regulation of organelle organization GO:0033043 80 0.023
carboxylic acid biosynthetic process GO:0046394 83 0.023
regulation of programmed cell death GO:0043067 341 0.023
growth GO:0040007 165 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.023
regulation of vesicle mediated transport GO:0060627 81 0.022
neurological system process GO:0050877 219 0.022
nucleoside triphosphate catabolic process GO:0009143 123 0.022
response to extracellular stimulus GO:0009991 380 0.022
regulation of cell proliferation GO:0042127 359 0.022
Mouse
alpha amino acid metabolic process GO:1901605 71 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.022
protein localization GO:0008104 191 0.022
cellular metal ion homeostasis GO:0006875 172 0.021
intracellular transport GO:0046907 185 0.021
heterocycle catabolic process GO:0046700 167 0.021
regulation of cell development GO:0060284 263 0.021
positive regulation of signaling GO:0023056 270 0.021
protein complex assembly GO:0006461 263 0.021
chemosensory behavior GO:0007635 2 0.021
behavior GO:0007610 205 0.021
response to wounding GO:0009611 254 0.021
negative regulation of signaling GO:0023057 157 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
salivary gland development GO:0007431 3 0.020
chemical homeostasis GO:0048878 292 0.020
Mouse
organonitrogen compound biosynthetic process GO:1901566 167 0.020
carbohydrate derivative catabolic process GO:1901136 147 0.020
guanosine containing compound metabolic process GO:1901068 74 0.020
sexual reproduction GO:0019953 148 0.020
Fly
single organism cellular localization GO:1902580 102 0.020
developmental growth GO:0048589 100 0.020
response to cytokine GO:0034097 215 0.020
regulation of secretion by cell GO:1903530 208 0.019
transcription dna templated GO:0006351 377 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
positive regulation of transport GO:0051050 245 0.019
cellular macromolecular complex assembly GO:0034622 58 0.019
neuron development GO:0048666 286 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
cellular homeostasis GO:0019725 252 0.019
cellular component morphogenesis GO:0032989 155 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.018
regulation of response to stress GO:0080134 126 0.018
amine metabolic process GO:0009308 38 0.018
multicellular organism growth GO:0035264 1 0.018
cellular protein complex assembly GO:0043623 44 0.018
purine containing compound catabolic process GO:0072523 138 0.018
lipid transport GO:0006869 61 0.018
lipid biosynthetic process GO:0008610 128 0.018
positive regulation of cell death GO:0010942 184 0.018
aging GO:0007568 241 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
regulation of cytoskeleton organization GO:0051493 49 0.018
cytoskeleton dependent cytokinesis GO:0061640 2 0.018
circulatory system development GO:0072359 134 0.018
single organism intracellular transport GO:1902582 166 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
neuron projection development GO:0031175 273 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
protein transport GO:0015031 132 0.017
regulation of catalytic activity GO:0050790 304 0.017
tissue development GO:0009888 252 0.017
Mouse
cellular ion homeostasis GO:0006873 184 0.017
signal release GO:0023061 145 0.017
single organism behavior GO:0044708 130 0.017
guanosine containing compound catabolic process GO:1901069 71 0.017
regulation of hormone levels GO:0010817 187 0.016
response to oxygen levels GO:0070482 265 0.016
regulation of protein metabolic process GO:0051246 289 0.016
hormone transport GO:0009914 121 0.016
ion transmembrane transport GO:0034220 365 0.016
negative regulation of metabolic process GO:0009892 331 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
regulation of signal transduction GO:0009966 318 0.016
regulation of body fluid levels GO:0050878 90 0.016
Mouse
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.016
multi multicellular organism process GO:0044706 138 0.016
response to growth factor GO:0070848 189 0.016
negative regulation of transport GO:0051051 136 0.016
positive regulation of cellular component organization GO:0051130 200 0.015
peptide secretion GO:0002790 86 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
asymmetric protein localization GO:0008105 2 0.015
cellular component maintenance GO:0043954 4 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
single organism organelle organization GO:1902589 180 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
regulation of transcription dna templated GO:0006355 374 0.015
neural crest cell differentiation GO:0014033 2 0.015
protein modification by small protein conjugation or removal GO:0070647 35 0.015
regulation of neuron differentiation GO:0045664 208 0.015
regulation of synaptic plasticity GO:0048167 70 0.015
cellular cation homeostasis GO:0030003 180 0.015
gtp metabolic process GO:0046039 72 0.015
metal ion homeostasis GO:0055065 186 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
morphogenesis of a polarized epithelium GO:0001738 1 0.015
cortical actin cytoskeleton organization GO:0030866 2 0.015
regulation of rna biosynthetic process GO:2001141 381 0.015
meiotic cell cycle process GO:1903046 3 0.015
response to other organism GO:0051707 220 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
response to hypoxia GO:0001666 231 0.014
olfactory behavior GO:0042048 2 0.014
positive regulation of nucleotide metabolic process GO:0045981 91 0.014
olfactory learning GO:0008355 1 0.014
cellular response to oxygen containing compound GO:1901701 386 0.014
regulation of membrane potential GO:0042391 110 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
regulation of cell projection organization GO:0031344 175 0.014
positive regulation of molecular function GO:0044093 230 0.014
hormone secretion GO:0046879 115 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
establishment of protein localization GO:0045184 141 0.014
rna biosynthetic process GO:0032774 380 0.014
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
axis specification GO:0009798 4 0.014
gtp catabolic process GO:0006184 71 0.014
cellular ketone metabolic process GO:0042180 51 0.014
anterior posterior pattern specification GO:0009952 1 0.013
defense response GO:0006952 194 0.013
regulation of rna metabolic process GO:0051252 391 0.013
cellular response to external stimulus GO:0071496 118 0.013
embryo development GO:0009790 49 0.013
reproductive structure development GO:0048608 128 0.013
cellular response to oxidative stress GO:0034599 76 0.013
phospholipid metabolic process GO:0006644 61 0.013
cell type specific apoptotic process GO:0097285 134 0.013
oxidation reduction process GO:0055114 304 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
reproductive system development GO:0061458 128 0.013
organic acid biosynthetic process GO:0016053 83 0.013
regulation of cellular component movement GO:0051270 150 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.013
leukocyte activation involved in immune response GO:0002366 16 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
positive regulation of immune system process GO:0002684 90 0.013
regulation of ion transport GO:0043269 245 0.013
regulation of actin filament based process GO:0032970 42 0.013
regulation of nervous system development GO:0051960 264 0.013
heart morphogenesis GO:0003007 3 0.013
intracellular signal transduction GO:0035556 314 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
Fly
syncytium formation by plasma membrane fusion GO:0000768 3 0.013
response to monosaccharide GO:0034284 159 0.013
synaptic vesicle transport GO:0048489 23 0.013
male gamete generation GO:0048232 99 0.012
Fly
organic anion transport GO:0015711 132 0.012
glycerolipid metabolic process GO:0046486 67 0.012
chromosome segregation GO:0007059 2 0.012
adult locomotory behavior GO:0008344 4 0.012
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.012
positive regulation of developmental process GO:0051094 283 0.012
spermatogenesis GO:0007283 99 0.012
Fly
rna metabolic process GO:0016070 406 0.012
positive regulation of secretion GO:0051047 140 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
response to decreased oxygen levels GO:0036293 237 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
positive regulation of immunoglobulin production GO:0002639 4 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
sex differentiation GO:0007548 113 0.012
regulation of phosphorylation GO:0042325 248 0.012
regulation of hydrolase activity GO:0051336 143 0.012
neural crest cell development GO:0014032 2 0.012
response to external biotic stimulus GO:0043207 221 0.012
head development GO:0060322 247 0.012
Mouse
cellular response to stress GO:0033554 269 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
response to peptide GO:1901652 292 0.012
regulation of synaptic transmission GO:0050804 141 0.012
regulation of immunoglobulin secretion GO:0051023 1 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
regulation of cellular component size GO:0032535 51 0.012
eye morphogenesis GO:0048592 4 0.011
Fly
lymphocyte activation involved in immune response GO:0002285 3 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
nitrogen compound transport GO:0071705 229 0.011
protein modification by small protein conjugation GO:0032446 31 0.011
cytoplasmic transport GO:0016482 115 0.011
b cell activation involved in immune response GO:0002312 1 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
response to glucose GO:0009749 136 0.011
regulation of dendrite development GO:0050773 59 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
nucleic acid templated transcription GO:0097659 379 0.011
bmp signaling pathway GO:0030509 4 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
negative regulation of cell death GO:0060548 229 0.011
peptide transport GO:0015833 97 0.011
immune system process GO:0002376 204 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
amide transport GO:0042886 105 0.011
negative regulation of innate immune response GO:0045824 4 0.011
regulation of nucleic acid templated transcription GO:1903506 380 0.011
erythrocyte differentiation GO:0030218 1 0.011
interleukin 12 production GO:0032615 3 0.011
sodium ion transport GO:0006814 82 0.011
transmission of nerve impulse GO:0019226 42 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
carbohydrate metabolic process GO:0005975 130 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
gliogenesis GO:0042063 93 0.010
cardiovascular system development GO:0072358 134 0.010
regulation of cellular catabolic process GO:0031329 101 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
glycerophospholipid metabolic process GO:0006650 47 0.010
regulation of immunoglobulin production GO:0002637 4 0.010
lipid storage GO:0019915 1 0.010
response to estradiol GO:0032355 164 0.010
negative regulation of actin filament polymerization GO:0030837 4 0.010
lipid localization GO:0010876 62 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
locomotion GO:0040011 237 0.010
liver development GO:0001889 90 0.010
Mouse
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 3 0.010
membrane budding GO:0006900 8 0.010
myoblast fusion GO:0007520 2 0.010
erythrocyte homeostasis GO:0034101 2 0.010
cellular response to peptide GO:1901653 133 0.010
peptide hormone secretion GO:0030072 84 0.010

Gak disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.047
muscular disease DOID:0080000 0 0.030
musculoskeletal system disease DOID:17 0 0.030
muscle tissue disease DOID:66 0 0.030
neuromuscular disease DOID:440 0 0.026
neuropathy DOID:870 0 0.026
disease of cellular proliferation DOID:14566 0 0.021
myopathy DOID:423 0 0.019
cancer DOID:162 0 0.018
organ system cancer DOID:0050686 0 0.015
vascular disease DOID:178 0 0.015
cardiovascular system disease DOID:1287 0 0.015
central nervous system disease DOID:331 0 0.014
charcot marie tooth disease DOID:10595 0 0.013
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013