Rattus norvegicus

64 known processes

Wasl

Wiskott-Aldrich syndrome-like

(Aliases: TRS4,N-WASP)

Wasl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 368 0.370
macromolecule localization GO:0033036 252 0.306
Mouse
cellular component biogenesis GO:0044085 368 0.264
regulation of neuron differentiation GO:0045664 208 0.247
cell projection organization GO:0030030 302 0.244
regulation of cellular component organization GO:0051128 368 0.240
intracellular transport GO:0046907 185 0.186
regulation of nervous system development GO:0051960 264 0.186
positive regulation of neurogenesis GO:0050769 165 0.179
cellular component assembly GO:0022607 360 0.179
protein phosphorylation GO:0006468 345 0.171
cellular amino acid metabolic process GO:0006520 107 0.157
regulation of multicellular organismal development GO:2000026 376 0.156
protein localization GO:0008104 191 0.154
Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.152
neuron development GO:0048666 286 0.151
regulation of signal transduction GO:0009966 318 0.133
regulation of cell development GO:0060284 263 0.132
regulation of phosphate metabolic process GO:0019220 349 0.132
positive regulation of cellular component organization GO:0051130 200 0.131
cell projection morphogenesis GO:0048858 123 0.123
central nervous system development GO:0007417 311 0.118
regulation of neuron projection development GO:0010975 161 0.117
organelle organization GO:0006996 266 0.116
regulation of cell projection organization GO:0031344 175 0.111
intracellular signal transduction GO:0035556 314 0.106
protein complex biogenesis GO:0070271 263 0.100
transcription dna templated GO:0006351 377 0.099
regulation of cell proliferation GO:0042127 359 0.098
rna metabolic process GO:0016070 406 0.095
organic acid metabolic process GO:0006082 292 0.095
enzyme linked receptor protein signaling pathway GO:0007167 116 0.094
protein autophosphorylation GO:0046777 66 0.092
actin filament based process GO:0030029 86 0.089
neuron projection development GO:0031175 273 0.085
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.083
establishment of protein localization GO:0045184 141 0.082
single organism catabolic process GO:0044712 283 0.082
regulation of cell differentiation GO:0045595 320 0.082
carboxylic acid metabolic process GO:0019752 289 0.080
positive regulation of multicellular organismal process GO:0051240 387 0.077
cellular response to oxygen containing compound GO:1901701 386 0.077
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.077
positive regulation of phosphate metabolic process GO:0045937 262 0.076
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.076
regulation of molecular function GO:0065009 398 0.074
response to estrogen GO:0043627 232 0.073
response to extracellular stimulus GO:0009991 380 0.073
positive regulation of phosphorus metabolic process GO:0010562 262 0.071
regulation of programmed cell death GO:0043067 341 0.070
negative regulation of multicellular organismal process GO:0051241 203 0.069
cell part morphogenesis GO:0032990 123 0.069
macromolecular complex assembly GO:0065003 273 0.067
regulation of nucleic acid templated transcription GO:1903506 380 0.066
regulation of phosphorylation GO:0042325 248 0.065
negative regulation of cell communication GO:0010648 158 0.064
purine nucleoside catabolic process GO:0006152 124 0.064
cellular amine metabolic process GO:0044106 38 0.062
nucleobase containing small molecule metabolic process GO:0055086 316 0.062
amine metabolic process GO:0009308 38 0.062
response to peptide hormone GO:0043434 278 0.062
locomotion GO:0040011 237 0.062
regulation of rna metabolic process GO:0051252 391 0.062
anatomical structure morphogenesis GO:0009653 298 0.061
membrane organization GO:0061024 94 0.060
tissue development GO:0009888 252 0.058
protein transport GO:0015031 132 0.058
positive regulation of rna metabolic process GO:0051254 203 0.057
rna biosynthetic process GO:0032774 380 0.057
regulation of protein modification process GO:0031399 194 0.056
positive regulation of programmed cell death GO:0043068 157 0.056
brain development GO:0007420 247 0.056
purine nucleotide metabolic process GO:0006163 229 0.055
negative regulation of developmental process GO:0051093 125 0.055
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.055
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.054
regulation of protein phosphorylation GO:0001932 183 0.054
purine containing compound metabolic process GO:0072521 253 0.053
localization of cell GO:0051674 202 0.053
catabolic process GO:0009056 351 0.052
negative regulation of signaling GO:0023057 157 0.051
cellular macromolecule localization GO:0070727 122 0.051
Mouse
negative regulation of signal transduction GO:0009968 83 0.050
organic substance catabolic process GO:1901575 316 0.050
behavior GO:0007610 205 0.050
response to wounding GO:0009611 254 0.049
regulation of anatomical structure morphogenesis GO:0022603 141 0.048
head development GO:0060322 247 0.047
cellular component morphogenesis GO:0032989 155 0.046
regulation of cell motility GO:2000145 131 0.045
cellular response to hormone stimulus GO:0032870 247 0.045
negative regulation of response to stimulus GO:0048585 155 0.044
reproductive process GO:0022414 372 0.044
regulation of cellular protein metabolic process GO:0032268 267 0.042
response to peptide GO:1901652 292 0.042
negative regulation of cellular metabolic process GO:0031324 281 0.041
regulation of intracellular signal transduction GO:1902531 218 0.041
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.041
negative regulation of macromolecule metabolic process GO:0010605 260 0.041
positive regulation of transcription dna templated GO:0045893 197 0.040
organophosphate metabolic process GO:0019637 370 0.040
regulation of dendrite development GO:0050773 59 0.039
positive regulation of molecular function GO:0044093 230 0.039
positive regulation of cell projection organization GO:0031346 111 0.039
nucleic acid templated transcription GO:0097659 379 0.039
regulation of transcription dna templated GO:0006355 374 0.038
circulatory system development GO:0072359 134 0.038
positive regulation of cell development GO:0010720 176 0.038
positive regulation of nervous system development GO:0051962 178 0.038
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.038
positive regulation of cell communication GO:0010647 271 0.037
positive regulation of cell differentiation GO:0045597 217 0.037
programmed cell death GO:0012501 392 0.037
cellular response to endogenous stimulus GO:0071495 377 0.037
positive regulation of nucleotide metabolic process GO:0045981 91 0.037
cytoskeleton organization GO:0007010 111 0.036
Mouse
regulation of neurogenesis GO:0050767 247 0.036
g protein coupled receptor signaling pathway GO:0007186 242 0.036
cell motility GO:0048870 202 0.036
regulation of cellular ketone metabolic process GO:0010565 27 0.036
growth GO:0040007 165 0.035
single organism reproductive process GO:0044702 297 0.034
ribose phosphate metabolic process GO:0019693 235 0.034
single organism intracellular transport GO:1902582 166 0.034
cellular response to stress GO:0033554 269 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.033
cardiovascular system development GO:0072358 134 0.033
cellular catabolic process GO:0044248 295 0.033
cell cell signaling GO:0007267 335 0.033
regulation of mapk cascade GO:0043408 116 0.033
positive regulation of nucleic acid templated transcription GO:1903508 197 0.033
positive regulation of gene expression GO:0010628 244 0.032
regulation of canonical wnt signaling pathway GO:0060828 4 0.032
response to organophosphorus GO:0046683 102 0.032
response to nutrient levels GO:0031667 370 0.032
regulation of cellular component movement GO:0051270 150 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.032
lipid metabolic process GO:0006629 283 0.032
chemical homeostasis GO:0048878 292 0.032
nucleoside phosphate metabolic process GO:0006753 283 0.032
homeostatic process GO:0042592 331 0.031
regulation of cell migration GO:0030334 128 0.031
regulation of cell cycle GO:0051726 73 0.031
negative regulation of metabolic process GO:0009892 331 0.031
cell migration GO:0016477 197 0.031
immune system process GO:0002376 204 0.031
positive regulation of phosphorylation GO:0042327 177 0.031
purine nucleoside metabolic process GO:0042278 169 0.030
purine ribonucleoside metabolic process GO:0046128 168 0.030
positive regulation of apoptotic process GO:0043065 154 0.030
learning or memory GO:0007611 90 0.030
cellular component movement GO:0006928 248 0.030
regulation of apoptotic process GO:0042981 335 0.030
cellular chemical homeostasis GO:0055082 247 0.029
regulation of protein metabolic process GO:0051246 289 0.029
heterocycle catabolic process GO:0046700 167 0.029
negative regulation of neurogenesis GO:0050768 78 0.029
intracellular protein transport GO:0006886 79 0.028
negative regulation of nervous system development GO:0051961 79 0.028
multicellular organism reproduction GO:0032504 233 0.028
regulation of kinase activity GO:0043549 117 0.028
positive regulation of neuron differentiation GO:0045666 126 0.028
regulation of endocytosis GO:0030100 42 0.028
negative regulation of cell development GO:0010721 82 0.028
purine ribonucleoside catabolic process GO:0046130 124 0.028
positive regulation of response to stimulus GO:0048584 285 0.028
negative regulation of biosynthetic process GO:0009890 168 0.027
cell morphogenesis GO:0000902 142 0.027
single organism membrane organization GO:0044802 74 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
regulation of cell morphogenesis GO:0022604 77 0.027
hematopoietic progenitor cell differentiation GO:0002244 2 0.027
cellular ketone metabolic process GO:0042180 51 0.027
organonitrogen compound biosynthetic process GO:1901566 167 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.027
purine ribonucleotide metabolic process GO:0009150 227 0.027
single organism organelle organization GO:1902589 180 0.027
Mouse
apoptotic process GO:0006915 381 0.027
transmembrane transport GO:0055085 412 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
response to acid chemical GO:0001101 222 0.026
cation homeostasis GO:0055080 195 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
actin cytoskeleton organization GO:0030036 73 0.025
Mouse
positive regulation of biosynthetic process GO:0009891 319 0.025
dendrite morphogenesis GO:0048813 43 0.025
cellular nitrogen compound catabolic process GO:0044270 163 0.025
single organism biosynthetic process GO:0044711 342 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
positive regulation of catalytic activity GO:0043085 184 0.025
negative regulation of gene expression GO:0010629 199 0.025
response to biotic stimulus GO:0009607 226 0.024
Mouse
regulation of establishment of protein localization GO:0070201 69 0.024
reproduction GO:0000003 245 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
metal ion transport GO:0030001 289 0.024
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
regulation of synaptic transmission GO:0050804 141 0.024
negative regulation of transcription dna templated GO:0045892 116 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
response to metal ion GO:0010038 253 0.024
response to bacterium GO:0009617 200 0.024
Mouse
peptidyl tyrosine phosphorylation GO:0018108 72 0.023
nucleotide metabolic process GO:0009117 279 0.023
oxoacid metabolic process GO:0043436 290 0.023
proteolysis GO:0006508 175 0.023
positive regulation of signaling GO:0023056 270 0.023
aromatic compound catabolic process GO:0019439 168 0.023
positive regulation of intracellular signal transduction GO:1902533 138 0.023
cell type specific apoptotic process GO:0097285 134 0.022
positive regulation of developmental process GO:0051094 283 0.022
protein complex assembly GO:0006461 263 0.022
response to other organism GO:0051707 220 0.022
Mouse
cellular homeostasis GO:0019725 252 0.022
cellular protein localization GO:0034613 122 0.022
Mouse
positive regulation of protein phosphorylation GO:0001934 135 0.022
response to cytokine GO:0034097 215 0.022
developmental growth GO:0048589 100 0.022
organophosphate biosynthetic process GO:0090407 143 0.022
regulation of immune system process GO:0002682 123 0.021
tube formation GO:0035148 3 0.021
synaptic transmission GO:0007268 235 0.021
neuron projection morphogenesis GO:0048812 122 0.021
cellular cation homeostasis GO:0030003 180 0.021
negative regulation of cellular component organization GO:0051129 83 0.021
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
positive regulation of signal transduction GO:0009967 175 0.020
nucleobase containing compound catabolic process GO:0034655 152 0.020
multi multicellular organism process GO:0044706 138 0.020
neurological system process GO:0050877 219 0.020
dephosphorylation GO:0016311 98 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
axon development GO:0061564 96 0.020
wound healing GO:0042060 122 0.020
cellular metal ion homeostasis GO:0006875 172 0.020
response to purine containing compound GO:0014074 126 0.020
response to molecule of bacterial origin GO:0002237 194 0.020
ras protein signal transduction GO:0007265 29 0.019
regulation of catalytic activity GO:0050790 304 0.019
ion homeostasis GO:0050801 212 0.019
ribonucleotide catabolic process GO:0009261 136 0.019
response to camp GO:0051591 91 0.019
metal ion homeostasis GO:0055065 186 0.019
cellular ion homeostasis GO:0006873 184 0.019
regulation of transferase activity GO:0051338 123 0.019
endocytosis GO:0006897 84 0.019
cell cycle GO:0007049 101 0.019
Mouse
positive regulation of protein modification process GO:0031401 142 0.019
cellular lipid metabolic process GO:0044255 208 0.019
monovalent inorganic cation transport GO:0015672 172 0.019
single organism behavior GO:0044708 130 0.019
cytoplasmic transport GO:0016482 115 0.019
anatomical structure formation involved in morphogenesis GO:0048646 83 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
axonogenesis GO:0007409 71 0.019
regulation of dendrite morphogenesis GO:0048814 33 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
rhythmic process GO:0048511 156 0.019
ribonucleoside metabolic process GO:0009119 174 0.018
nucleoside phosphate catabolic process GO:1901292 140 0.018
regulation of protein kinase activity GO:0045859 105 0.018
phospholipid metabolic process GO:0006644 61 0.018
glycerolipid metabolic process GO:0046486 67 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
cognition GO:0050890 92 0.018
response to growth factor GO:0070848 189 0.018
secretion GO:0046903 307 0.018
chromosome segregation GO:0007059 2 0.018
ribonucleoside triphosphate metabolic process GO:0009199 141 0.018
peptidyl amino acid modification GO:0018193 126 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
negative regulation of phosphorus metabolic process GO:0010563 80 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
ribonucleoside catabolic process GO:0042454 126 0.018
multi organism reproductive process GO:0044703 262 0.018
cell adhesion GO:0007155 110 0.018
organonitrogen compound catabolic process GO:1901565 179 0.017
glycosyl compound catabolic process GO:1901658 126 0.017
regulation of homeostatic process GO:0032844 101 0.017
regulation of locomotion GO:0040012 148 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
actin filament organization GO:0007015 42 0.017
anterior posterior pattern specification GO:0009952 1 0.017
cell junction organization GO:0034330 21 0.017
positive regulation of cell death GO:0010942 184 0.017
reproductive structure development GO:0048608 128 0.017
neuron death GO:0070997 127 0.017
epithelium development GO:0060429 96 0.017
vesicle mediated transport GO:0016192 181 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.016
positive regulation of cell motility GO:2000147 97 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
cation transport GO:0006812 382 0.016
secretion by tissue GO:0032941 37 0.016
protein complex subunit organization GO:0071822 302 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
response to oxygen levels GO:0070482 265 0.016
regulation of protein transport GO:0051223 68 0.015
negative regulation of neuron differentiation GO:0045665 62 0.015
protein targeting GO:0006605 61 0.015
response to hypoxia GO:0001666 231 0.015
response to nutrient GO:0007584 248 0.015
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.015
calcium ion transport GO:0006816 131 0.015
sexual reproduction GO:0019953 148 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
response to carbohydrate GO:0009743 183 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
cellular macromolecular complex assembly GO:0034622 58 0.014
establishment of tissue polarity GO:0007164 2 0.014
positive regulation of protein kinase activity GO:0045860 73 0.014
cellular response to peptide hormone stimulus GO:0071375 120 0.014
regulation of synaptic plasticity GO:0048167 70 0.014
muscle structure development GO:0061061 87 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
response to ethanol GO:0045471 162 0.014
cell cycle checkpoint GO:0000075 2 0.014
response to decreased oxygen levels GO:0036293 237 0.014
regulation of embryonic development GO:0045995 2 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
nucleoside monophosphate metabolic process GO:0009123 93 0.014
multicellular organism growth GO:0035264 1 0.013
negative regulation of secretion by cell GO:1903531 72 0.013
ion transmembrane transport GO:0034220 365 0.013
regulation of secretion by cell GO:1903530 208 0.013
glycerophospholipid metabolic process GO:0006650 47 0.013
nucleocytoplasmic transport GO:0006913 48 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
positive regulation of protein tyrosine kinase activity GO:0061098 2 0.013
response to hexose GO:0009746 144 0.013
cation transmembrane transport GO:0098655 263 0.013
regulation of cytoskeleton organization GO:0051493 49 0.013
response to insulin GO:0032868 133 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
gland development GO:0048732 155 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
positive regulation of immune system process GO:0002684 90 0.012
embryonic placenta development GO:0001892 1 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
lipid biosynthetic process GO:0008610 128 0.012
lipid localization GO:0010876 62 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
calcium ion homeostasis GO:0055074 162 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
negative regulation of molecular function GO:0044092 133 0.012
reproductive system development GO:0061458 128 0.012
cellular protein complex assembly GO:0043623 44 0.012
sequestering of calcium ion GO:0051208 8 0.012
memory GO:0007613 54 0.012
male mating behavior GO:0060179 3 0.012
ossification GO:0001503 70 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
response to reactive oxygen species GO:0000302 120 0.012
female pregnancy GO:0007565 122 0.012
wnt signaling pathway GO:0016055 17 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
regulation of membrane potential GO:0042391 110 0.011
response to retinoic acid GO:0032526 63 0.011
protein dephosphorylation GO:0006470 38 0.011
nucleoside metabolic process GO:0009116 179 0.011
negative regulation of cell death GO:0060548 229 0.011
regulation of response to wounding GO:1903034 69 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
nucleoside catabolic process GO:0009164 126 0.011
neuromuscular synaptic transmission GO:0007274 2 0.011
negative regulation of cell projection organization GO:0031345 50 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
negative regulation of transport GO:0051051 136 0.011
response to lipopolysaccharide GO:0032496 191 0.011
chemosensory behavior GO:0007635 2 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
mitotic spindle organization GO:0007052 2 0.011
response to inorganic substance GO:0010035 377 0.011
camera type eye morphogenesis GO:0048593 2 0.011
gastrulation GO:0007369 2 0.011
nucleotide catabolic process GO:0009166 139 0.011
regulation of cellular component size GO:0032535 51 0.011
regulation of growth GO:0040008 105 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
sex differentiation GO:0007548 113 0.011
positive regulation of transferase activity GO:0051347 81 0.011
regulation of actin cytoskeleton organization GO:0032956 30 0.011
response to external biotic stimulus GO:0043207 221 0.010
Mouse
regulation of organelle organization GO:0033043 80 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
cellular response to oxidative stress GO:0034599 76 0.010
cellular response to peptide GO:1901653 133 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
response to glucose GO:0009749 136 0.010
peptidyl serine modification GO:0018209 34 0.010
regulation of anatomical structure size GO:0090066 135 0.010
hepaticobiliary system development GO:0061008 90 0.010
mammary gland development GO:0030879 38 0.010
regulation of secretion GO:0051046 224 0.010
heart development GO:0007507 72 0.010
regulation of dna metabolic process GO:0051052 60 0.010
regulation of cellular catabolic process GO:0031329 101 0.010
cellular response to drug GO:0035690 30 0.010
negative regulation of cell proliferation GO:0008285 119 0.010

Wasl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
disease of cellular proliferation DOID:14566 0 0.015
central nervous system disease DOID:331 0 0.011