Rattus norvegicus

0 known processes

Best2

bestrophin 2

(Aliases: Vmd2l1)

Best2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of rna biosynthetic process GO:2001141 381 0.165
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.146
anatomical structure morphogenesis GO:0009653 298 0.137
carboxylic acid metabolic process GO:0019752 289 0.131
oxoacid metabolic process GO:0043436 290 0.131
organic acid metabolic process GO:0006082 292 0.127
carbohydrate derivative metabolic process GO:1901135 346 0.102
macromolecule localization GO:0033036 252 0.097
nucleic acid templated transcription GO:0097659 379 0.091
regulation of nucleic acid templated transcription GO:1903506 380 0.089
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.086
rna biosynthetic process GO:0032774 380 0.086
apoptotic process GO:0006915 381 0.078
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.074
homeostatic process GO:0042592 331 0.074
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.072
organic substance catabolic process GO:1901575 316 0.071
programmed cell death GO:0012501 392 0.067
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.066
positive regulation of biosynthetic process GO:0009891 319 0.066
chemical homeostasis GO:0048878 292 0.065
Fly
purine containing compound metabolic process GO:0072521 253 0.065
positive regulation of gene expression GO:0010628 244 0.063
nucleobase containing small molecule metabolic process GO:0055086 316 0.062
positive regulation of transcription dna templated GO:0045893 197 0.061
intracellular signal transduction GO:0035556 314 0.061
regulation of cellular component organization GO:0051128 368 0.057
regulation of transcription dna templated GO:0006355 374 0.057
nucleotide metabolic process GO:0009117 279 0.056
regulation of multicellular organismal development GO:2000026 376 0.056
positive regulation of cellular biosynthetic process GO:0031328 295 0.056
glycosyl compound metabolic process GO:1901657 182 0.055
cellular amino acid metabolic process GO:0006520 107 0.054
transcription dna templated GO:0006351 377 0.054
regulation of apoptotic process GO:0042981 335 0.054
nucleoside phosphate metabolic process GO:0006753 283 0.053
single organism catabolic process GO:0044712 283 0.053
ion transmembrane transport GO:0034220 365 0.052
Fly
regulation of rna metabolic process GO:0051252 391 0.050
purine ribonucleoside metabolic process GO:0046128 168 0.046
mesoderm development GO:0007498 2 0.046
neuron differentiation GO:0030182 368 0.045
regulation of molecular function GO:0065009 398 0.045
organophosphate metabolic process GO:0019637 370 0.043
ribonucleoside metabolic process GO:0009119 174 0.043
transcription from rna polymerase ii promoter GO:0006366 252 0.043
purine ribonucleotide metabolic process GO:0009150 227 0.043
cellular catabolic process GO:0044248 295 0.043
catabolic process GO:0009056 351 0.042
glycosyl compound catabolic process GO:1901658 126 0.041
positive regulation of rna metabolic process GO:0051254 203 0.041
regulation of nucleotide metabolic process GO:0006140 117 0.041
purine nucleotide metabolic process GO:0006163 229 0.040
nucleoside metabolic process GO:0009116 179 0.040
regulation of phosphate metabolic process GO:0019220 349 0.039
secretion GO:0046903 307 0.039
cellular component assembly GO:0022607 360 0.038
single organism biosynthetic process GO:0044711 342 0.038
anion transport GO:0006820 178 0.038
Fly
purine nucleoside metabolic process GO:0042278 169 0.038
secretion by cell GO:0032940 248 0.038
regulation of secretion GO:0051046 224 0.037
ribose phosphate metabolic process GO:0019693 235 0.036
negative regulation of metabolic process GO:0009892 331 0.036
positive regulation of phosphate metabolic process GO:0045937 262 0.036
cell cell signaling GO:0007267 335 0.036
positive regulation of multicellular organismal process GO:0051240 387 0.035
organic cyclic compound catabolic process GO:1901361 175 0.035
positive regulation of molecular function GO:0044093 230 0.035
regulation of cell proliferation GO:0042127 359 0.035
regulation of cellular localization GO:0060341 263 0.034
positive regulation of programmed cell death GO:0043068 157 0.034
brain development GO:0007420 247 0.034
rna metabolic process GO:0016070 406 0.034
ribonucleotide metabolic process GO:0009259 231 0.033
regulation of programmed cell death GO:0043067 341 0.033
organic acid transport GO:0015849 116 0.033
organic acid biosynthetic process GO:0016053 83 0.032
monocarboxylic acid metabolic process GO:0032787 152 0.031
organelle organization GO:0006996 266 0.031
cell projection organization GO:0030030 302 0.031
regulation of response to stress GO:0080134 126 0.031
regulation of system process GO:0044057 208 0.031
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.031
negative regulation of response to stimulus GO:0048585 155 0.031
carboxylic acid biosynthetic process GO:0046394 83 0.031
positive regulation of cell differentiation GO:0045597 217 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
negative regulation of nucleic acid templated transcription GO:1903507 117 0.030
cellular nitrogen compound catabolic process GO:0044270 163 0.030
negative regulation of cell communication GO:0010648 158 0.029
negative regulation of developmental process GO:0051093 125 0.029
positive regulation of cell proliferation GO:0008284 249 0.029
cellular amine metabolic process GO:0044106 38 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
cellular ketone metabolic process GO:0042180 51 0.028
cellular component movement GO:0006928 248 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.028
neuron projection development GO:0031175 273 0.028
macromolecular complex assembly GO:0065003 273 0.028
nucleobase containing compound catabolic process GO:0034655 152 0.028
purine nucleoside triphosphate metabolic process GO:0009144 141 0.028
regulation of cell differentiation GO:0045595 320 0.028
amine metabolic process GO:0009308 38 0.027
cellular component biogenesis GO:0044085 368 0.027
positive regulation of developmental process GO:0051094 283 0.027
regulation of anatomical structure morphogenesis GO:0022603 141 0.027
regulation of phosphorylation GO:0042325 248 0.027
negative regulation of programmed cell death GO:0043069 183 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
protein complex subunit organization GO:0071822 302 0.026
regulation of cell projection organization GO:0031344 175 0.026
cell morphogenesis involved in differentiation GO:0000904 119 0.026
negative regulation of signal transduction GO:0009968 83 0.026
regulation of protein metabolic process GO:0051246 289 0.026
nitrogen compound transport GO:0071705 229 0.026
carbohydrate derivative catabolic process GO:1901136 147 0.026
positive regulation of cell death GO:0010942 184 0.026
regulation of neuron differentiation GO:0045664 208 0.026
protein phosphorylation GO:0006468 345 0.025
negative regulation of signaling GO:0023057 157 0.025
regulation of cellular component movement GO:0051270 150 0.025
ribonucleoside triphosphate metabolic process GO:0009199 141 0.025
regulation of neuron projection development GO:0010975 161 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.024
fibrinolysis GO:0042730 2 0.024
aromatic compound catabolic process GO:0019439 168 0.023
regulation of signal transduction GO:0009966 318 0.023
small molecule biosynthetic process GO:0044283 124 0.023
regulation of cell development GO:0060284 263 0.023
cellular homeostasis GO:0019725 252 0.023
Fly
macromolecular complex subunit organization GO:0043933 339 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
response to oxidative stress GO:0006979 186 0.023
tissue development GO:0009888 252 0.023
response to peptide hormone GO:0043434 278 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
fatty acid metabolic process GO:0006631 99 0.022
negative regulation of transport GO:0051051 136 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.022
regulation of catalytic activity GO:0050790 304 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
epithelial cell differentiation GO:0030855 71 0.022
negative regulation of gene expression GO:0010629 199 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
response to extracellular stimulus GO:0009991 380 0.021
response to wounding GO:0009611 254 0.021
regulation of hydrolase activity GO:0051336 143 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
ras protein signal transduction GO:0007265 29 0.021
organ morphogenesis GO:0009887 75 0.020
central nervous system development GO:0007417 311 0.020
single organism organelle organization GO:1902589 180 0.020
purine ribonucleoside catabolic process GO:0046130 124 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
proteolysis GO:0006508 175 0.020
nucleoside triphosphate metabolic process GO:0009141 144 0.020
heterocycle catabolic process GO:0046700 167 0.020
transmembrane transport GO:0055085 412 0.020
Fly
head development GO:0060322 247 0.020
regulation of response to external stimulus GO:0032101 106 0.020
multicellular organism growth GO:0035264 1 0.020
regulation of nervous system development GO:0051960 264 0.019
single organism reproductive process GO:0044702 297 0.019
regulation of neurogenesis GO:0050767 247 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.019
epithelium development GO:0060429 96 0.019
lipid transport GO:0006869 61 0.019
lipid metabolic process GO:0006629 283 0.019
positive regulation of ion transport GO:0043270 94 0.019
regulation of leukocyte activation GO:0002694 45 0.019
neuron fate commitment GO:0048663 4 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
response to monosaccharide GO:0034284 159 0.018
cell morphogenesis GO:0000902 142 0.018
protein complex assembly GO:0006461 263 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
regulation of protein phosphorylation GO:0001932 183 0.018
purine nucleotide catabolic process GO:0006195 136 0.018
hormone transport GO:0009914 121 0.018
response to camp GO:0051591 91 0.018
negative regulation of cell death GO:0060548 229 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
cellular response to stress GO:0033554 269 0.017
nucleoside catabolic process GO:0009164 126 0.017
response to nutrient GO:0007584 248 0.017
lipid localization GO:0010876 62 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
positive regulation of signaling GO:0023056 270 0.017
protein complex biogenesis GO:0070271 263 0.017
negative regulation of response to external stimulus GO:0032102 37 0.017
circulatory system process GO:0003013 183 0.017
single organism intracellular transport GO:1902582 166 0.017
positive regulation of blood coagulation GO:0030194 4 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
regulation of secretion by cell GO:1903530 208 0.017
cellular component morphogenesis GO:0032989 155 0.017
reproductive process GO:0022414 372 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
tongue morphogenesis GO:0043587 3 0.016
macromolecule catabolic process GO:0009057 58 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
response to inorganic substance GO:0010035 377 0.016
ribonucleotide catabolic process GO:0009261 136 0.016
aging GO:0007568 241 0.016
response to nutrient levels GO:0031667 370 0.016
purine nucleoside catabolic process GO:0006152 124 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
sex differentiation GO:0007548 113 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
regulation of ion transport GO:0043269 245 0.016
Fly
connective tissue development GO:0061448 33 0.016
nucleoside triphosphate catabolic process GO:0009143 123 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
negative regulation of cell proliferation GO:0008285 119 0.015
regulation of body fluid levels GO:0050878 90 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
response to peptide GO:1901652 292 0.015
response to organophosphorus GO:0046683 102 0.015
defense response GO:0006952 194 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
reproductive structure development GO:0048608 128 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
developmental process involved in reproduction GO:0003006 159 0.015
regulation of fibrinolysis GO:0051917 2 0.015
cell fate commitment involved in pattern specification GO:0060581 2 0.015
unsaturated fatty acid biosynthetic process GO:0006636 21 0.015
neuron development GO:0048666 286 0.015
cation transport GO:0006812 382 0.015
male sex differentiation GO:0046661 64 0.015
organophosphate catabolic process GO:0046434 148 0.015
organic hydroxy compound transport GO:0015850 77 0.014
positive regulation of hydrolase activity GO:0051345 86 0.014
monocarboxylic acid biosynthetic process GO:0072330 48 0.014
response to temperature stimulus GO:0009266 94 0.014
cell part morphogenesis GO:0032990 123 0.014
hormone secretion GO:0046879 115 0.014
cell adhesion GO:0007155 110 0.014
neuron projection morphogenesis GO:0048812 122 0.014
reproductive system development GO:0061458 128 0.014
regulation of hormone levels GO:0010817 187 0.014
cellular lipid metabolic process GO:0044255 208 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
fatty acid biosynthetic process GO:0006633 33 0.014
signal release GO:0023061 145 0.014
response to hexose GO:0009746 144 0.014
cation transmembrane transport GO:0098655 263 0.014
regulation of purine nucleotide catabolic process GO:0033121 65 0.014
membrane organization GO:0061024 94 0.014
protein localization GO:0008104 191 0.014
negative regulation of secretion GO:0051048 82 0.013
development of primary sexual characteristics GO:0045137 107 0.013
response to carbohydrate GO:0009743 183 0.013
gonad development GO:0008406 104 0.013
morphogenesis of embryonic epithelium GO:0016331 3 0.013
tube formation GO:0035148 3 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
heart morphogenesis GO:0003007 3 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
lipid biosynthetic process GO:0008610 128 0.013
negative regulation of ion transport GO:0043271 51 0.013
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
lipid storage GO:0019915 1 0.012
response to metal ion GO:0010038 253 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
Fly
response to purine containing compound GO:0014074 126 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
locomotion GO:0040011 237 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
organ formation GO:0048645 3 0.012
protein processing GO:0016485 68 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
acid secretion GO:0046717 48 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
negative regulation of rna metabolic process GO:0051253 123 0.011
regulation of insulin secretion GO:0050796 65 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
regulation of immune system process GO:0002682 123 0.011
regulation of catabolic process GO:0009894 113 0.011
leukocyte cell cell adhesion GO:0007159 4 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
positive regulation of nucleoside metabolic process GO:0045979 55 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
sensory perception GO:0007600 101 0.011
positive regulation of protein modification process GO:0031401 142 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
dna metabolic process GO:0006259 96 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
regulation of nucleoside metabolic process GO:0009118 66 0.011
gliogenesis GO:0042063 93 0.011
gland development GO:0048732 155 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
peptide hormone secretion GO:0030072 84 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
defecation GO:0030421 1 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
vasculature development GO:0001944 70 0.011
positive regulation of catabolic process GO:0009896 78 0.011
regulation of cellular response to stress GO:0080135 49 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
response to estrogen GO:0043627 232 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
regulation of response to wounding GO:1903034 69 0.010
immune system process GO:0002376 204 0.010
single organism cellular localization GO:1902580 102 0.010
response to acid chemical GO:0001101 222 0.010
regulation of peptide secretion GO:0002791 82 0.010
cellular protein localization GO:0034613 122 0.010
neural tube formation GO:0001841 1 0.010
response to glucose GO:0009749 136 0.010
insulin secretion GO:0030073 69 0.010

Best2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038
sensory system disease DOID:0050155 0 0.033
musculoskeletal system disease DOID:17 0 0.029
eye and adnexa disease DOID:1492 0 0.024
eye disease DOID:5614 0 0.024
bone development disease DOID:0080006 0 0.011
bone disease DOID:0080001 0 0.011
connective tissue disease DOID:65 0 0.011
disease of metabolism DOID:0014667 0 0.011
retinal disease DOID:5679 0 0.010
retinal degeneration DOID:8466 0 0.010