Rattus norvegicus

117 known processes

Keap1

Kelch-like ECH-associated protein 1

(Aliases: Inrf2)

Keap1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 377 0.108
regulation of rna metabolic process GO:0051252 391 0.094
rna biosynthetic process GO:0032774 380 0.083
rna metabolic process GO:0016070 406 0.068
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.057
positive regulation of gene expression GO:0010628 244 0.055
organic substance catabolic process GO:1901575 316 0.054
Human
regulation of apoptotic process GO:0042981 335 0.053
positive regulation of cellular biosynthetic process GO:0031328 295 0.049
cellular response to endogenous stimulus GO:0071495 377 0.048
cellular response to hormone stimulus GO:0032870 247 0.047
positive regulation of transcription dna templated GO:0045893 197 0.047
regulation of nucleic acid templated transcription GO:1903506 380 0.046
regulation of rna biosynthetic process GO:2001141 381 0.046
nucleotide metabolic process GO:0009117 279 0.046
response to inorganic substance GO:0010035 377 0.045
regulation of transcription dna templated GO:0006355 374 0.045
ribonucleotide metabolic process GO:0009259 231 0.045
nucleoside phosphate metabolic process GO:0006753 283 0.043
purine nucleoside triphosphate catabolic process GO:0009146 122 0.042
cellular response to oxygen containing compound GO:1901701 386 0.042
positive regulation of biosynthetic process GO:0009891 319 0.041
programmed cell death GO:0012501 392 0.041
positive regulation of rna metabolic process GO:0051254 203 0.041
apoptotic process GO:0006915 381 0.040
catabolic process GO:0009056 351 0.040
Human
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.039
nucleic acid templated transcription GO:0097659 379 0.039
purine ribonucleotide metabolic process GO:0009150 227 0.039
negative regulation of macromolecule metabolic process GO:0010605 260 0.039
transcription from rna polymerase ii promoter GO:0006366 252 0.038
positive regulation of nucleic acid templated transcription GO:1903508 197 0.038
ribose phosphate metabolic process GO:0019693 235 0.038
cellular catabolic process GO:0044248 295 0.038
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
regulation of cell proliferation GO:0042127 359 0.037
positive regulation of multicellular organismal process GO:0051240 387 0.037
Rat
purine ribonucleoside metabolic process GO:0046128 168 0.036
purine nucleotide metabolic process GO:0006163 229 0.036
regulation of programmed cell death GO:0043067 341 0.035
positive regulation of developmental process GO:0051094 283 0.034
Rat
ribonucleoside metabolic process GO:0009119 174 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.034
vesicle mediated transport GO:0016192 181 0.033
purine containing compound metabolic process GO:0072521 253 0.032
heterocycle catabolic process GO:0046700 167 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
single organism intracellular transport GO:1902582 166 0.031
response to peptide GO:1901652 292 0.031
nucleoside monophosphate metabolic process GO:0009123 93 0.031
purine nucleoside catabolic process GO:0006152 124 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.030
organonitrogen compound catabolic process GO:1901565 179 0.030
regulation of molecular function GO:0065009 398 0.030
regulation of cell differentiation GO:0045595 320 0.029
Rat
neuron projection development GO:0031175 273 0.028
Rat
multicellular organism reproduction GO:0032504 233 0.028
regulation of signal transduction GO:0009966 318 0.027
protein transport GO:0015031 132 0.027
response to extracellular stimulus GO:0009991 380 0.027
cellular response to organonitrogen compound GO:0071417 197 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
intracellular signal transduction GO:0035556 314 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.025
positive regulation of molecular function GO:0044093 230 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
intracellular transport GO:0046907 185 0.025
regulation of protein metabolic process GO:0051246 289 0.025
response to peptide hormone GO:0043434 278 0.025
ribonucleoside catabolic process GO:0042454 126 0.025
negative regulation of rna metabolic process GO:0051253 123 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.024
negative regulation of metabolic process GO:0009892 331 0.024
reproductive process GO:0022414 372 0.024
nucleotide catabolic process GO:0009166 139 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
ribonucleoside triphosphate catabolic process GO:0009203 122 0.023
glycosyl compound catabolic process GO:1901658 126 0.023
ribonucleoside triphosphate metabolic process GO:0009199 141 0.023
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.022
negative regulation of cellular biosynthetic process GO:0031327 161 0.022
negative regulation of gene expression GO:0010629 199 0.022
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
reproductive system development GO:0061458 128 0.022
neurological system process GO:0050877 219 0.022
cellular response to lipid GO:0071396 201 0.022
nucleoside triphosphate metabolic process GO:0009141 144 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.021
single organism organelle organization GO:1902589 180 0.021
Rat
cellular component biogenesis GO:0044085 368 0.021
multi organism reproductive process GO:0044703 262 0.021
cellular response to peptide GO:1901653 133 0.021
neuron differentiation GO:0030182 368 0.021
Rat
regulation of phosphate metabolic process GO:0019220 349 0.021
protein localization GO:0008104 191 0.021
glycosyl compound metabolic process GO:1901657 182 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
chromosome segregation GO:0007059 2 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
purine ribonucleoside catabolic process GO:0046130 124 0.020
regulation of neurogenesis GO:0050767 247 0.020
Rat
negative regulation of rna biosynthetic process GO:1902679 118 0.020
single organism biosynthetic process GO:0044711 342 0.020
cellular protein localization GO:0034613 122 0.020
regulation of cellular localization GO:0060341 263 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
neuron development GO:0048666 286 0.019
Rat
organelle organization GO:0006996 266 0.019
Rat
homeostatic process GO:0042592 331 0.019
organophosphate metabolic process GO:0019637 370 0.019
growth GO:0040007 165 0.018
aromatic compound catabolic process GO:0019439 168 0.018
regulation of cellular component organization GO:0051128 368 0.018
Rat
single organism reproductive process GO:0044702 297 0.018
regulation of catalytic activity GO:0050790 304 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
Rat
regulation of cellular catabolic process GO:0031329 101 0.018
nucleoside triphosphate catabolic process GO:0009143 123 0.017
nucleoside metabolic process GO:0009116 179 0.017
cellular component assembly GO:0022607 360 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
organophosphate catabolic process GO:0046434 148 0.017
response to nutrient levels GO:0031667 370 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
reproduction GO:0000003 245 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
response to oxidative stress GO:0006979 186 0.017
purine nucleoside monophosphate catabolic process GO:0009128 55 0.017
protein phosphorylation GO:0006468 345 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
purine containing compound catabolic process GO:0072523 138 0.017
brain development GO:0007420 247 0.017
Rat
purine ribonucleotide catabolic process GO:0009154 136 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
macromolecule localization GO:0033036 252 0.016
cytoplasmic transport GO:0016482 115 0.016
organic acid metabolic process GO:0006082 292 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
cellular amine metabolic process GO:0044106 38 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
ribonucleotide catabolic process GO:0009261 136 0.016
regulation of protein modification process GO:0031399 194 0.016
macromolecule catabolic process GO:0009057 58 0.016
Human
cellular response to stress GO:0033554 269 0.016
nucleoside catabolic process GO:0009164 126 0.016
cellular macromolecule localization GO:0070727 122 0.016
regulation of phosphorylation GO:0042325 248 0.016
regulation of multicellular organismal development GO:2000026 376 0.015
Rat
purine nucleoside monophosphate metabolic process GO:0009126 84 0.015
cell projection organization GO:0030030 302 0.015
Rat
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.015
regulation of membrane potential GO:0042391 110 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
response to reactive oxygen species GO:0000302 120 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
establishment of protein localization GO:0045184 141 0.015
axon development GO:0061564 96 0.015
membrane organization GO:0061024 94 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
regulation of system process GO:0044057 208 0.014
central nervous system development GO:0007417 311 0.014
Rat
ribonucleoside monophosphate catabolic process GO:0009158 55 0.014
atp catabolic process GO:0006200 54 0.014
single organism catabolic process GO:0044712 283 0.014
response to bacterium GO:0009617 200 0.014
female pregnancy GO:0007565 122 0.014
gamete generation GO:0007276 124 0.014
peptidyl amino acid modification GO:0018193 126 0.014
defense response GO:0006952 194 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.014
response to biotic stimulus GO:0009607 226 0.014
cellular component movement GO:0006928 248 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
response to radiation GO:0009314 137 0.014
ribonucleoside monophosphate metabolic process GO:0009161 88 0.014
developmental process involved in reproduction GO:0003006 159 0.014
purine nucleoside metabolic process GO:0042278 169 0.013
development of primary sexual characteristics GO:0045137 107 0.013
cellular response to external stimulus GO:0071496 118 0.013
positive regulation of protein modification process GO:0031401 142 0.013
atp metabolic process GO:0046034 72 0.013
negative regulation of cell cycle phase transition GO:1901988 4 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
negative regulation of cell death GO:0060548 229 0.013
positive regulation of transport GO:0051050 245 0.013
aging GO:0007568 241 0.013
response to decreased oxygen levels GO:0036293 237 0.013
positive regulation of nervous system development GO:0051962 178 0.013
Rat
nucleoside monophosphate catabolic process GO:0009125 56 0.013
muscle structure development GO:0061061 87 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
Rat
nitrogen compound transport GO:0071705 229 0.013
immune system process GO:0002376 204 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
reproductive structure development GO:0048608 128 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
oxoacid metabolic process GO:0043436 290 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
amine metabolic process GO:0009308 38 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
divalent inorganic cation transport GO:0072511 134 0.013
positive regulation of cell development GO:0010720 176 0.012
Rat
anatomical structure morphogenesis GO:0009653 298 0.012
regulation of cell projection organization GO:0031344 175 0.012
Rat
response to oxygen levels GO:0070482 265 0.012
proteolysis GO:0006508 175 0.012
Human
embryonic pattern specification GO:0009880 1 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
single organism cellular localization GO:1902580 102 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
response to growth factor GO:0070848 189 0.012
lipid storage GO:0019915 1 0.012
cardiac chamber development GO:0003205 1 0.012
response to cytokine GO:0034097 215 0.012
regulation of kinase activity GO:0043549 117 0.012
protein complex subunit organization GO:0071822 302 0.012
multi multicellular organism process GO:0044706 138 0.012
positive regulation of signaling GO:0023056 270 0.011
immune response GO:0006955 104 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
response to nutrient GO:0007584 248 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
multicellular organism growth GO:0035264 1 0.011
positive regulation of catabolic process GO:0009896 78 0.011
regulation of growth GO:0040008 105 0.011
lipid metabolic process GO:0006629 283 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
response to estradiol GO:0032355 164 0.011
cytokine biosynthetic process GO:0042089 3 0.011
cellular ketone metabolic process GO:0042180 51 0.011
positive regulation of signal transduction GO:0009967 175 0.011
response to metal ion GO:0010038 253 0.011
neuromuscular process GO:0050905 2 0.011
blood circulation GO:0008015 183 0.011
biological adhesion GO:0022610 110 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
calcium ion transport GO:0006816 131 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
gland development GO:0048732 155 0.011
muscle system process GO:0003012 115 0.011
response to mechanical stimulus GO:0009612 134 0.011
ras protein signal transduction GO:0007265 29 0.011
negative regulation of transport GO:0051051 136 0.011
negative regulation of innate immune response GO:0045824 4 0.011
regulation of nervous system development GO:0051960 264 0.011
Rat
protein complex assembly GO:0006461 263 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
Rat
response to insulin GO:0032868 133 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.010
positive regulation of protein metabolic process GO:0051247 178 0.010
regulation of cytokine biosynthetic process GO:0042035 3 0.010
secretion GO:0046903 307 0.010
negative regulation of developmental process GO:0051093 125 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
response to hydrogen peroxide GO:0042542 89 0.010
male gamete generation GO:0048232 99 0.010
regulation of neuron differentiation GO:0045664 208 0.010
Rat
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
response to corticosteroid GO:0031960 235 0.010
cation transport GO:0006812 382 0.010
jak stat cascade GO:0007259 26 0.010
negative regulation of molecular function GO:0044092 133 0.010
cell growth GO:0016049 104 0.010
cofactor metabolic process GO:0051186 95 0.010
chemosensory behavior GO:0007635 2 0.010
cell cycle GO:0007049 101 0.010
double strand break repair GO:0006302 1 0.010
neuron death GO:0070997 127 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
lipid biosynthetic process GO:0008610 128 0.010
sexual reproduction GO:0019953 148 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010

Keap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
nervous system disease DOID:863 0 0.018
central nervous system disease DOID:331 0 0.013
musculoskeletal system disease DOID:17 0 0.012