Rattus norvegicus

7 known processes

Pgpep1

pyroglutamyl-peptidase I

(Aliases: PAPI)

Pgpep1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna biosynthetic process GO:0032774 380 0.048
nucleic acid templated transcription GO:0097659 379 0.043
oxoacid metabolic process GO:0043436 290 0.041
macromolecular complex subunit organization GO:0043933 339 0.036
mesoderm development GO:0007498 2 0.036
immune system process GO:0002376 204 0.034
cation transport GO:0006812 382 0.033
regulation of transcription dna templated GO:0006355 374 0.032
cellular component biogenesis GO:0044085 368 0.031
homeostatic process GO:0042592 331 0.028
cellular amino acid metabolic process GO:0006520 107 0.027
head development GO:0060322 247 0.027
positive regulation of rna biosynthetic process GO:1902680 197 0.027
regulation of nucleic acid templated transcription GO:1903506 380 0.025
blood circulation GO:0008015 183 0.025
rna metabolic process GO:0016070 406 0.025
reproduction GO:0000003 245 0.024
regulation of system process GO:0044057 208 0.024
organic acid metabolic process GO:0006082 292 0.024
ion transmembrane transport GO:0034220 365 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
neuron differentiation GO:0030182 368 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
response to oxygen levels GO:0070482 265 0.022
heart morphogenesis GO:0003007 3 0.022
cellular chemical homeostasis GO:0055082 247 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
regulation of molecular function GO:0065009 398 0.022
cell motility GO:0048870 202 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
localization of cell GO:0051674 202 0.022
ion homeostasis GO:0050801 212 0.022
brain development GO:0007420 247 0.021
organic substance catabolic process GO:1901575 316 0.021
protein localization GO:0008104 191 0.021
single organism organelle organization GO:1902589 180 0.021
reproductive process GO:0022414 372 0.021
negative regulation of metabolic process GO:0009892 331 0.021
anatomical structure morphogenesis GO:0009653 298 0.021
transmembrane transport GO:0055085 412 0.020
single organism catabolic process GO:0044712 283 0.020
multicellular organism reproduction GO:0032504 233 0.020
protein complex assembly GO:0006461 263 0.020
multi organism reproductive process GO:0044703 262 0.020
single organism biosynthetic process GO:0044711 342 0.019
response to growth factor GO:0070848 189 0.019
cell projection organization GO:0030030 302 0.019
response to decreased oxygen levels GO:0036293 237 0.019
regulation of cell differentiation GO:0045595 320 0.019
response to ketone GO:1901654 182 0.019
response to hypoxia GO:0001666 231 0.018
membrane organization GO:0061024 94 0.018
cellular homeostasis GO:0019725 252 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
cellular amine metabolic process GO:0044106 38 0.018
cellular component assembly GO:0022607 360 0.018
neurological system process GO:0050877 219 0.018
cellular component movement GO:0006928 248 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
nitrogen compound transport GO:0071705 229 0.018
regulation of cellular component organization GO:0051128 368 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
amine metabolic process GO:0009308 38 0.018
catabolic process GO:0009056 351 0.018
macromolecular complex assembly GO:0065003 273 0.018
transcription dna templated GO:0006351 377 0.018
neuron projection development GO:0031175 273 0.017
protein complex biogenesis GO:0070271 263 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
neuron development GO:0048666 286 0.017
response to nutrient levels GO:0031667 370 0.017
cellular catabolic process GO:0044248 295 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
regulation of rna metabolic process GO:0051252 391 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
ras protein signal transduction GO:0007265 29 0.016
positive regulation of molecular function GO:0044093 230 0.016
chemical homeostasis GO:0048878 292 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
defense response GO:0006952 194 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
reproductive structure development GO:0048608 128 0.016
response to carbohydrate GO:0009743 183 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
carbohydrate metabolic process GO:0005975 130 0.016
regulation of immune system process GO:0002682 123 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
organophosphate metabolic process GO:0019637 370 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
metal ion homeostasis GO:0055065 186 0.015
embryonic skeletal system morphogenesis GO:0048704 3 0.015
gastrulation GO:0007369 2 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
response to monosaccharide GO:0034284 159 0.015
developmental process involved in reproduction GO:0003006 159 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
cation homeostasis GO:0055080 195 0.015
response to inorganic substance GO:0010035 377 0.015
neural crest cell differentiation GO:0014033 2 0.015
regulation of phosphate metabolic process GO:0019220 349 0.015
single organism reproductive process GO:0044702 297 0.015
cell communication involved in cardiac conduction GO:0086065 2 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
organelle organization GO:0006996 266 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
response to ethanol GO:0045471 162 0.015
aging GO:0007568 241 0.015
metal ion transport GO:0030001 289 0.015
lipid metabolic process GO:0006629 283 0.015
regulation of catabolic process GO:0009894 113 0.015
response to external biotic stimulus GO:0043207 221 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
cardiac conduction GO:0061337 2 0.014
secretion GO:0046903 307 0.014
circulatory system process GO:0003013 183 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
cellular macromolecule localization GO:0070727 122 0.014
actin cytoskeleton organization GO:0030036 73 0.014
apoptotic process GO:0006915 381 0.014
motor neuron axon guidance GO:0008045 1 0.014
response to extracellular stimulus GO:0009991 380 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
cellular ketone metabolic process GO:0042180 51 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
regulation of cell development GO:0060284 263 0.014
response to metal ion GO:0010038 253 0.014
positive regulation of gene expression GO:0010628 244 0.014
response to biotic stimulus GO:0009607 226 0.014
positive regulation of cell death GO:0010942 184 0.014
coenzyme metabolic process GO:0006732 86 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
macromolecule localization GO:0033036 252 0.014
cellular response to oxygen containing compound GO:1901701 386 0.013
response to other organism GO:0051707 220 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
vesicle mediated transport GO:0016192 181 0.013
protein oligomerization GO:0051259 191 0.013
protein complex subunit organization GO:0071822 302 0.013
regulation of membrane potential GO:0042391 110 0.013
intracellular signal transduction GO:0035556 314 0.013
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.013
sexual reproduction GO:0019953 148 0.013
eye morphogenesis GO:0048592 4 0.013
central nervous system development GO:0007417 311 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
regulation of multicellular organismal development GO:2000026 376 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
locomotion GO:0040011 237 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
axis specification GO:0009798 4 0.012
response to hexose GO:0009746 144 0.012
cell cell signaling GO:0007267 335 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
cellular ion homeostasis GO:0006873 184 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
neuronal action potential GO:0019228 35 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
embryonic pattern specification GO:0009880 1 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
gliogenesis GO:0042063 93 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
formation of primary germ layer GO:0001704 1 0.012
adult locomotory behavior GO:0008344 4 0.012
response to corticosteroid GO:0031960 235 0.012
positive regulation of developmental process GO:0051094 283 0.012
protein phosphorylation GO:0006468 345 0.012
regulation of organelle organization GO:0033043 80 0.011
nucleotide metabolic process GO:0009117 279 0.011
biological adhesion GO:0022610 110 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
cellular cation homeostasis GO:0030003 180 0.011
cell adhesion GO:0007155 110 0.011
cation transmembrane transport GO:0098655 263 0.011
negative regulation of gene expression GO:0010629 199 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
response to retinoic acid GO:0032526 63 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
regulation of catalytic activity GO:0050790 304 0.011
regulation of protein metabolic process GO:0051246 289 0.011
gamete generation GO:0007276 124 0.011
regulation of phosphorus metabolic process GO:0051174 349 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
developmental induction GO:0031128 2 0.011
multicellular organismal signaling GO:0035637 44 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
regulation of secretion by cell GO:1903530 208 0.011
response to wounding GO:0009611 254 0.011
actin filament based process GO:0030029 86 0.011
cellular component morphogenesis GO:0032989 155 0.011
microtubule organizing center organization GO:0031023 1 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
muscle system process GO:0003012 115 0.011
anion transport GO:0006820 178 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
purine containing compound metabolic process GO:0072521 253 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
positive regulation of response to stimulus GO:0048584 285 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
cell part morphogenesis GO:0032990 123 0.010
cofactor metabolic process GO:0051186 95 0.010
ribose phosphate metabolic process GO:0019693 235 0.010
regeneration GO:0031099 163 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
oligopeptide transport GO:0006857 4 0.010
response to acid chemical GO:0001101 222 0.010
forebrain development GO:0030900 98 0.010

Pgpep1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.011