Rattus norvegicus

65 known processes

Txn1

thioredoxin 1

(Aliases: Txn)

Txn1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
catabolic process GO:0009056 351 0.491
nucleic acid templated transcription GO:0097659 379 0.212
Mouse
cellular catabolic process GO:0044248 295 0.181
rna metabolic process GO:0016070 406 0.173
Mouse
cellular response to stress GO:0033554 269 0.168
regulation of rna metabolic process GO:0051252 391 0.154
Mouse
ribonucleotide metabolic process GO:0009259 231 0.147
regulation of molecular function GO:0065009 398 0.142
Human
macromolecular complex subunit organization GO:0043933 339 0.128
homeostatic process GO:0042592 331 0.119
regulation of cellular localization GO:0060341 263 0.116
Human Mouse
multicellular organismal homeostasis GO:0048871 49 0.114
rna biosynthetic process GO:0032774 380 0.107
Mouse
organophosphate metabolic process GO:0019637 370 0.106
cellular response to oxygen containing compound GO:1901701 386 0.103
organic substance catabolic process GO:1901575 316 0.102
cellular component assembly GO:0022607 360 0.099
nucleoside phosphate metabolic process GO:0006753 283 0.099
negative regulation of cellular metabolic process GO:0031324 281 0.097
Mouse
regulation of transcription dna templated GO:0006355 374 0.094
Mouse
negative regulation of metabolic process GO:0009892 331 0.092
Mouse
regulation of nucleic acid templated transcription GO:1903506 380 0.087
Mouse
regulation of phosphate metabolic process GO:0019220 349 0.084
Human
transcription dna templated GO:0006351 377 0.080
Mouse
macromolecular complex assembly GO:0065003 273 0.080
aging GO:0007568 241 0.079
ion transmembrane transport GO:0034220 365 0.074
proteolysis GO:0006508 175 0.072
metal ion transport GO:0030001 289 0.072
cell projection organization GO:0030030 302 0.069
regulation of rna biosynthetic process GO:2001141 381 0.067
Mouse
immune system process GO:0002376 204 0.065
multi organism reproductive process GO:0044703 262 0.064
vesicle mediated transport GO:0016192 181 0.064
negative regulation of gene expression GO:0010629 199 0.063
Mouse
neuron development GO:0048666 286 0.061
transcription from rna polymerase ii promoter GO:0006366 252 0.061
Mouse
regulation of calcium ion transmembrane transport GO:1903169 18 0.060
programmed cell death GO:0012501 392 0.060
secretion by cell GO:0032940 248 0.059
negative regulation of rna biosynthetic process GO:1902679 118 0.058
Mouse
cellular component biogenesis GO:0044085 368 0.057
reproduction GO:0000003 245 0.056
cation transport GO:0006812 382 0.056
purine nucleotide metabolic process GO:0006163 229 0.055
positive regulation of intracellular signal transduction GO:1902533 138 0.052
positive regulation of cell communication GO:0010647 271 0.052
protein complex subunit organization GO:0071822 302 0.052
protein transport GO:0015031 132 0.051
Human Mouse
multicellular organism reproduction GO:0032504 233 0.051
oxidation reduction process GO:0055114 304 0.051
Human Mouse
response to wounding GO:0009611 254 0.051
positive regulation of phosphate metabolic process GO:0045937 262 0.050
Human
neuron projection development GO:0031175 273 0.048
response to glucocorticoid GO:0051384 223 0.048
inorganic ion transmembrane transport GO:0098660 229 0.047
neuron differentiation GO:0030182 368 0.047
response to other organism GO:0051707 220 0.045
macromolecule localization GO:0033036 252 0.045
Human Mouse
single organism catabolic process GO:0044712 283 0.045
positive regulation of signaling GO:0023056 270 0.044
macromolecule catabolic process GO:0009057 58 0.043
nucleoside triphosphate metabolic process GO:0009141 144 0.043
neuron death GO:0070997 127 0.041
synaptic transmission GO:0007268 235 0.041
regulation of protein transport GO:0051223 68 0.039
Human Mouse
negative regulation of transcription dna templated GO:0045892 116 0.039
Mouse
inorganic cation transmembrane transport GO:0098662 202 0.039
protein complex assembly GO:0006461 263 0.039
single organism reproductive process GO:0044702 297 0.038
response to biotic stimulus GO:0009607 226 0.038
nucleotide metabolic process GO:0009117 279 0.037
tissue development GO:0009888 252 0.037
regulation of calcium ion transmembrane transporter activity GO:1901019 17 0.037
positive regulation of molecular function GO:0044093 230 0.037
Human
cation transmembrane transport GO:0098655 263 0.035
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.035
Mouse
regulation of signal transduction GO:0009966 318 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
purine containing compound metabolic process GO:0072521 253 0.034
multicellular organismal reproductive process GO:0048609 233 0.034
establishment of protein localization GO:0045184 141 0.034
Human Mouse
divalent metal ion transport GO:0070838 132 0.034
intracellular protein transport GO:0006886 79 0.033
Human Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.033
Human
response to acid chemical GO:0001101 222 0.033
regulation of catabolic process GO:0009894 113 0.032
organelle organization GO:0006996 266 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
regulation of cell morphogenesis GO:0022604 77 0.031
regulation of cell development GO:0060284 263 0.031
purine nucleoside metabolic process GO:0042278 169 0.030
pseudopodium assembly GO:0031269 3 0.030
carbohydrate derivative metabolic process GO:1901135 346 0.030
inflammatory response GO:0006954 150 0.030
response to inorganic substance GO:0010035 377 0.030
regulation of transmembrane transporter activity GO:0022898 49 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.029
head development GO:0060322 247 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
calcium ion transport GO:0006816 131 0.028
glycosyl compound metabolic process GO:1901657 182 0.028
regulation of catalytic activity GO:0050790 304 0.028
positive regulation of signal transduction GO:0009967 175 0.028
synaptic growth at neuromuscular junction GO:0051124 1 0.028
negative regulation of response to stimulus GO:0048585 155 0.028
Human
negative regulation of cell death GO:0060548 229 0.028
Human
regulation of protein modification process GO:0031399 194 0.028
Human
response to external biotic stimulus GO:0043207 221 0.028
ribonucleoside triphosphate metabolic process GO:0009199 141 0.028
negative regulation of rna metabolic process GO:0051253 123 0.028
Mouse
response to monosaccharide GO:0034284 159 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.027
Mouse
protein phosphorylation GO:0006468 345 0.027
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
Mouse
response to amine GO:0014075 46 0.027
anatomical structure morphogenesis GO:0009653 298 0.027
response to bacterium GO:0009617 200 0.026
developmental process involved in reproduction GO:0003006 159 0.026
immune response GO:0006955 104 0.026
regulation of cellular protein metabolic process GO:0032268 267 0.025
Human
nucleoside metabolic process GO:0009116 179 0.025
nucleoside phosphate biosynthetic process GO:1901293 102 0.025
purine ribonucleoside metabolic process GO:0046128 168 0.025
defense response GO:0006952 194 0.025
endocytosis GO:0006897 84 0.025
response to metal ion GO:0010038 253 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
regulation of ion transmembrane transporter activity GO:0032412 48 0.024
circulatory system process GO:0003013 183 0.024
negative regulation of cell communication GO:0010648 158 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.024
Mouse
single organism organelle organization GO:1902589 180 0.023
secretion GO:0046903 307 0.023
regulation of apoptotic process GO:0042981 335 0.023
negative regulation of biosynthetic process GO:0009890 168 0.023
Mouse
ribose phosphate metabolic process GO:0019693 235 0.023
positive regulation of transport GO:0051050 245 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
Mouse
ribose phosphate biosynthetic process GO:0046390 87 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
response to oxidative stress GO:0006979 186 0.022
Human
reproductive process GO:0022414 372 0.022
regulation of ion transport GO:0043269 245 0.022
anatomical structure homeostasis GO:0060249 29 0.022
response to peptide GO:1901652 292 0.021
striated muscle tissue development GO:0014706 58 0.021
nucleobase containing compound catabolic process GO:0034655 152 0.021
purine nucleotide catabolic process GO:0006195 136 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
regulation of secretion GO:0051046 224 0.020
regulation of protein localization GO:0032880 81 0.020
Human Mouse
chemical homeostasis GO:0048878 292 0.020
response to hexose GO:0009746 144 0.020
regulation of intracellular signal transduction GO:1902531 218 0.019
cell cell signaling GO:0007267 335 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
transmembrane transport GO:0055085 412 0.019
apoptotic process GO:0006915 381 0.019
telencephalon development GO:0021537 62 0.019
regulation of ion transmembrane transport GO:0034765 121 0.019
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
Human
positive regulation of catalytic activity GO:0043085 184 0.018
embryo development GO:0009790 49 0.018
reproductive structure development GO:0048608 128 0.018
protein oligomerization GO:0051259 191 0.018
regulation of establishment of protein localization GO:0070201 69 0.017
Human Mouse
negative regulation of skeletal muscle cell differentiation GO:2001015 1 0.017
calcium ion transmembrane transport GO:0070588 70 0.017
negative regulation of skeletal muscle tissue development GO:0048642 3 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
locomotion GO:0040011 237 0.017
response to ethanol GO:0045471 162 0.017
cellular component morphogenesis GO:0032989 155 0.016
negative regulation of signaling GO:0023057 157 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
gamete generation GO:0007276 124 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
skin morphogenesis GO:0043589 2 0.016
growth GO:0040007 165 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
regulation of protein kinase activity GO:0045859 105 0.016
viral genome replication GO:0019079 2 0.015
protein complex biogenesis GO:0070271 263 0.015
regulation of neuron death GO:1901214 115 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
regulation of kinase activity GO:0043549 117 0.015
regulation of protein metabolic process GO:0051246 289 0.015
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
cell morphogenesis GO:0000902 142 0.015
regulation of programmed cell death GO:0043067 341 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
Human
response to carbohydrate GO:0009743 183 0.014
protein localization GO:0008104 191 0.014
Human Mouse
negative regulation of transport GO:0051051 136 0.014
Mouse
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
regulation of hydrolase activity GO:0051336 143 0.014
regulation of cell differentiation GO:0045595 320 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
carboxylic acid transport GO:0046942 115 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
central nervous system development GO:0007417 311 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
spliceosomal complex assembly GO:0000245 2 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
cytoplasmic transport GO:0016482 115 0.013
Human Mouse
positive regulation of cell proliferation GO:0008284 249 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
Human
sexual reproduction GO:0019953 148 0.012
cellular homeostasis GO:0019725 252 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
Mouse
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
Mouse
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
Human
blood circulation GO:0008015 183 0.011
cellular response to endogenous stimulus GO:0071495 377 0.011
forebrain development GO:0030900 98 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
single organism membrane organization GO:0044802 74 0.011
regulation of cellular component organization GO:0051128 368 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
single organism cell adhesion GO:0098602 46 0.011
adult locomotory behavior GO:0008344 4 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
Mouse
single organism behavior GO:0044708 130 0.011
positive regulation of gene expression GO:0010628 244 0.011
divalent inorganic cation transport GO:0072511 134 0.011
positive regulation of transferase activity GO:0051347 81 0.011
pseudopodium organization GO:0031268 3 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
cell part morphogenesis GO:0032990 123 0.010
protein modification by small protein conjugation GO:0032446 31 0.010
biological adhesion GO:0022610 110 0.010
positive regulation of rna biosynthetic process GO:1902680 197 0.010
gtp metabolic process GO:0046039 72 0.010

Txn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
central nervous system disease DOID:331 0 0.011
brain disease DOID:936 0 0.011