Rattus norvegicus

30 known processes

Ckb

creatine kinase, brain

(Aliases: Ckbb,RATCKBR,Ckbr)

Ckb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.292
Rat
response to external biotic stimulus GO:0043207 221 0.212
oxoacid metabolic process GO:0043436 290 0.183
Rat
response to corticosteroid GO:0031960 235 0.169
programmed cell death GO:0012501 392 0.146
response to other organism GO:0051707 220 0.144
carboxylic acid metabolic process GO:0019752 289 0.140
Rat
response to extracellular stimulus GO:0009991 380 0.132
wound healing GO:0042060 122 0.129
response to insulin GO:0032868 133 0.116
regulation of cellular component organization GO:0051128 368 0.111
reproductive process GO:0022414 372 0.111
response to biotic stimulus GO:0009607 226 0.110
response to glucocorticoid GO:0051384 223 0.107
response to nutrient levels GO:0031667 370 0.107
response to peptide hormone GO:0043434 278 0.101
cellular catabolic process GO:0044248 295 0.098
response to acid chemical GO:0001101 222 0.092
response to estrogen GO:0043627 232 0.091
ribose phosphate metabolic process GO:0019693 235 0.089
catabolic process GO:0009056 351 0.087
response to peptide GO:1901652 292 0.087
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.085
single organism catabolic process GO:0044712 283 0.081
cellular response to oxygen containing compound GO:1901701 386 0.078
response to oxygen levels GO:0070482 265 0.077
protein complex subunit organization GO:0071822 302 0.075
organic substance catabolic process GO:1901575 316 0.075
response to camp GO:0051591 91 0.075
positive regulation of multicellular organismal process GO:0051240 387 0.074
monocarboxylic acid metabolic process GO:0032787 152 0.072
amine metabolic process GO:0009308 38 0.071
cellular amino acid metabolic process GO:0006520 107 0.070
Rat
regulation of protein metabolic process GO:0051246 289 0.069
purine containing compound metabolic process GO:0072521 253 0.067
regulation of cellular amine metabolic process GO:0033238 8 0.067
carbohydrate derivative metabolic process GO:1901135 346 0.066
regulation of phosphorus metabolic process GO:0051174 349 0.066
tissue development GO:0009888 252 0.063
response to decreased oxygen levels GO:0036293 237 0.063
purine ribonucleotide metabolic process GO:0009150 227 0.062
response to bacterium GO:0009617 200 0.062
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.061
cellular response to peptide hormone stimulus GO:0071375 120 0.061
response to monosaccharide GO:0034284 159 0.061
anatomical structure morphogenesis GO:0009653 298 0.061
purine nucleotide metabolic process GO:0006163 229 0.060
regulation of multicellular organismal development GO:2000026 376 0.060
positive regulation of cell communication GO:0010647 271 0.060
response to inorganic substance GO:0010035 377 0.060
regulation of apoptotic process GO:0042981 335 0.060
regulation of cellular amino acid metabolic process GO:0006521 2 0.059
macromolecular complex subunit organization GO:0043933 339 0.059
regulation of phosphate metabolic process GO:0019220 349 0.058
proteolysis GO:0006508 175 0.058
cellular ketone metabolic process GO:0042180 51 0.058
protein complex biogenesis GO:0070271 263 0.057
regulation of cell differentiation GO:0045595 320 0.056
response to hexose GO:0009746 144 0.055
response to nutrient GO:0007584 248 0.055
regulation of cell proliferation GO:0042127 359 0.055
nucleotide metabolic process GO:0009117 279 0.054
response to estradiol GO:0032355 164 0.054
aging GO:0007568 241 0.053
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.053
transcription dna templated GO:0006351 377 0.053
purine ribonucleoside metabolic process GO:0046128 168 0.053
response to hypoxia GO:0001666 231 0.052
regeneration GO:0031099 163 0.052
cellular component assembly GO:0022607 360 0.052
nucleoside triphosphate metabolic process GO:0009141 144 0.051
cellular response to peptide GO:1901653 133 0.051
response to wounding GO:0009611 254 0.050
localization of cell GO:0051674 202 0.050
cellular component biogenesis GO:0044085 368 0.050
growth GO:0040007 165 0.049
negative regulation of molecular function GO:0044092 133 0.049
cell projection organization GO:0030030 302 0.049
cellular response to hormone stimulus GO:0032870 247 0.048
response to purine containing compound GO:0014074 126 0.048
glycosyl compound metabolic process GO:1901657 182 0.048
cellular component movement GO:0006928 248 0.047
positive regulation of cellular component organization GO:0051130 200 0.047
response to cytokine GO:0034097 215 0.047
purine nucleoside metabolic process GO:0042278 169 0.046
response to carbohydrate GO:0009743 183 0.046
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.046
cellular amine metabolic process GO:0044106 38 0.046
regulation of phosphorylation GO:0042325 248 0.046
response to oxidative stress GO:0006979 186 0.045
neuron projection development GO:0031175 273 0.045
regulation of hydrolase activity GO:0051336 143 0.045
response to lipopolysaccharide GO:0032496 191 0.045
multi multicellular organism process GO:0044706 138 0.044
cellular response to nitrogen compound GO:1901699 210 0.044
positive regulation of phosphorus metabolic process GO:0010562 262 0.043
negative regulation of metabolic process GO:0009892 331 0.042
brain development GO:0007420 247 0.042
response to alkaloid GO:0043279 132 0.042
apoptotic process GO:0006915 381 0.042
response to organophosphorus GO:0046683 102 0.042
negative regulation of response to stimulus GO:0048585 155 0.041
nitrogen compound transport GO:0071705 229 0.041
neuron development GO:0048666 286 0.040
purine nucleoside triphosphate metabolic process GO:0009144 141 0.040
cell part morphogenesis GO:0032990 123 0.040
cellular response to external stimulus GO:0071496 118 0.040
organelle organization GO:0006996 266 0.040
negative regulation of cellular metabolic process GO:0031324 281 0.039
head development GO:0060322 247 0.039
regulation of cellular ketone metabolic process GO:0010565 27 0.039
nucleoside metabolic process GO:0009116 179 0.038
peptidyl tyrosine modification GO:0018212 72 0.038
regulation of cellular protein metabolic process GO:0032268 267 0.038
ribonucleotide metabolic process GO:0009259 231 0.038
tissue regeneration GO:0042246 36 0.037
regulation of nervous system development GO:0051960 264 0.037
circulatory system process GO:0003013 183 0.036
gland development GO:0048732 155 0.036
cellular cation homeostasis GO:0030003 180 0.036
cell motility GO:0048870 202 0.036
organophosphate metabolic process GO:0019637 370 0.036
Rat
response to metal ion GO:0010038 253 0.035
secretion by cell GO:0032940 248 0.035
neuron differentiation GO:0030182 368 0.035
lipid metabolic process GO:0006629 283 0.035
positive regulation of cellular amine metabolic process GO:0033240 3 0.035
protein phosphorylation GO:0006468 345 0.035
positive regulation of apoptotic process GO:0043065 154 0.034
positive regulation of developmental process GO:0051094 283 0.034
cellular response to endogenous stimulus GO:0071495 377 0.034
cellular response to insulin stimulus GO:0032869 81 0.033
regulation of protein phosphorylation GO:0001932 183 0.033
female pregnancy GO:0007565 122 0.033
generation of precursor metabolites and energy GO:0006091 62 0.033
regulation of molecular function GO:0065009 398 0.033
nucleobase containing small molecule metabolic process GO:0055086 316 0.033
organic cyclic compound catabolic process GO:1901361 175 0.033
central nervous system development GO:0007417 311 0.033
response to heat GO:0009408 60 0.033
sensory organ development GO:0007423 74 0.033
response to glucose GO:0009749 136 0.033
transcription from rna polymerase ii promoter GO:0006366 252 0.032
oxidation reduction process GO:0055114 304 0.032
regulation of secretion by cell GO:1903530 208 0.032
cellular metal ion homeostasis GO:0006875 172 0.032
cellular nitrogen compound catabolic process GO:0044270 163 0.032
locomotion GO:0040011 237 0.032
rna biosynthetic process GO:0032774 380 0.032
positive regulation of nervous system development GO:0051962 178 0.032
chemical homeostasis GO:0048878 292 0.032
nucleoside phosphate metabolic process GO:0006753 283 0.032
cellular chemical homeostasis GO:0055082 247 0.031
positive regulation of signaling GO:0023056 270 0.031
purine nucleotide catabolic process GO:0006195 136 0.031
regulation of cellular localization GO:0060341 263 0.031
response to growth factor GO:0070848 189 0.030
positive regulation of molecular function GO:0044093 230 0.030
response to radiation GO:0009314 137 0.030
cellular response to stress GO:0033554 269 0.030
carbohydrate catabolic process GO:0016052 40 0.030
transmembrane transport GO:0055085 412 0.030
protein complex assembly GO:0006461 263 0.030
response to amino acid GO:0043200 75 0.030
cell cell signaling GO:0007267 335 0.030
multi organism reproductive process GO:0044703 262 0.029
developmental process involved in reproduction GO:0003006 159 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
eye development GO:0001654 50 0.029
response to temperature stimulus GO:0009266 94 0.029
positive regulation of cell death GO:0010942 184 0.028
cellular response to organonitrogen compound GO:0071417 197 0.028
ribonucleoside triphosphate metabolic process GO:0009199 141 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
positive regulation of signal transduction GO:0009967 175 0.027
response to lithium ion GO:0010226 28 0.027
regulation of cell development GO:0060284 263 0.027
response to transition metal nanoparticle GO:1990267 122 0.027
positive regulation of cell development GO:0010720 176 0.027
positive regulation of response to stimulus GO:0048584 285 0.026
metal ion homeostasis GO:0055065 186 0.026
defense response GO:0006952 194 0.026
cell growth GO:0016049 104 0.026
regulation of catalytic activity GO:0050790 304 0.026
cellular response to growth factor stimulus GO:0071363 162 0.026
protein localization GO:0008104 191 0.026
cellular homeostasis GO:0019725 252 0.026
purine nucleoside triphosphate catabolic process GO:0009146 122 0.026
cellular divalent inorganic cation homeostasis GO:0072503 162 0.025
regulation of blood pressure GO:0008217 83 0.025
divalent inorganic cation homeostasis GO:0072507 165 0.025
positive regulation of cell projection organization GO:0031346 111 0.025
cellular lipid metabolic process GO:0044255 208 0.025
regulation of programmed cell death GO:0043067 341 0.025
positive regulation of phosphorylation GO:0042327 177 0.025
glycosyl compound catabolic process GO:1901658 126 0.025
protein processing GO:0016485 68 0.025
macromolecular complex assembly GO:0065003 273 0.024
heterocycle catabolic process GO:0046700 167 0.024
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.024
organophosphate catabolic process GO:0046434 148 0.024
carbohydrate derivative biosynthetic process GO:1901137 124 0.024
regulation of organelle organization GO:0033043 80 0.024
carbohydrate metabolic process GO:0005975 130 0.023
single organism biosynthetic process GO:0044711 342 0.023
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.023
cellular response to lipid GO:0071396 201 0.023
organonitrogen compound catabolic process GO:1901565 179 0.023
regulation of rna biosynthetic process GO:2001141 381 0.023
regulation of protein modification process GO:0031399 194 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
single organism organelle organization GO:1902589 180 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.022
reproduction GO:0000003 245 0.022
regulation of hormone levels GO:0010817 187 0.022
regulation of neurogenesis GO:0050767 247 0.022
single organism carbohydrate metabolic process GO:0044723 118 0.022
purine nucleoside catabolic process GO:0006152 124 0.022
positive regulation of programmed cell death GO:0043068 157 0.022
blood circulation GO:0008015 183 0.022
purine containing compound catabolic process GO:0072523 138 0.022
cation homeostasis GO:0055080 195 0.022
ribonucleoside metabolic process GO:0009119 174 0.022
regulation of metal ion transport GO:0010959 118 0.022
negative regulation of catalytic activity GO:0043086 103 0.021
regulation of rna metabolic process GO:0051252 391 0.021
nucleoside phosphate catabolic process GO:1901292 140 0.021
hepaticobiliary system development GO:0061008 90 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
single organism membrane organization GO:0044802 74 0.021
positive regulation of protein modification process GO:0031401 142 0.021
atp metabolic process GO:0046034 72 0.021
reproductive system development GO:0061458 128 0.021
cellular component morphogenesis GO:0032989 155 0.021
homeostatic process GO:0042592 331 0.020
aromatic compound catabolic process GO:0019439 168 0.020
ribonucleoside catabolic process GO:0042454 126 0.020
enzyme linked receptor protein signaling pathway GO:0007167 116 0.020
protein homooligomerization GO:0051260 91 0.020
response to molecule of bacterial origin GO:0002237 194 0.020
heart morphogenesis GO:0003007 3 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
metal ion transport GO:0030001 289 0.020
single organism carbohydrate catabolic process GO:0044724 40 0.020
macromolecule localization GO:0033036 252 0.020
regulation of secretion GO:0051046 224 0.020
regulation of transcription dna templated GO:0006355 374 0.019
negative regulation of apoptotic process GO:0043066 181 0.019
circulatory system development GO:0072359 134 0.019
rna metabolic process GO:0016070 406 0.019
ribonucleotide catabolic process GO:0009261 136 0.019
positive regulation of transport GO:0051050 245 0.019
regulation of cell projection organization GO:0031344 175 0.019
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
calcium ion homeostasis GO:0055074 162 0.019
carboxylic acid biosynthetic process GO:0046394 83 0.019
Rat
secretion GO:0046903 307 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
cellular ion homeostasis GO:0006873 184 0.019
organ regeneration GO:0031100 101 0.019
ribose phosphate biosynthetic process GO:0046390 87 0.019
epithelium development GO:0060429 96 0.019
glycogen metabolic process GO:0005977 23 0.019
regulation of system process GO:0044057 208 0.019
pyruvate metabolic process GO:0006090 27 0.018
regulation of nucleic acid templated transcription GO:1903506 380 0.018
cell morphogenesis GO:0000902 142 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.018
purine containing compound biosynthetic process GO:0072522 85 0.018
cellular amide metabolic process GO:0043603 44 0.018
neuron projection morphogenesis GO:0048812 122 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
regulation of ion transport GO:0043269 245 0.018
chemotaxis GO:0006935 66 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
regulation of anatomical structure size GO:0090066 135 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
cellular response to organic cyclic compound GO:0071407 202 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
response to ethanol GO:0045471 162 0.017
negative regulation of phosphate metabolic process GO:0045936 80 0.017
response to light stimulus GO:0009416 52 0.017
nucleic acid templated transcription GO:0097659 379 0.017
developmental growth GO:0048589 100 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.016
small molecule biosynthetic process GO:0044283 124 0.016
Rat
reproductive structure development GO:0048608 128 0.016
intracellular transport GO:0046907 185 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
regulation of neuron differentiation GO:0045664 208 0.016
regulation of response to external stimulus GO:0032101 106 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
regulation of body fluid levels GO:0050878 90 0.016
response to ketone GO:1901654 182 0.016
positive regulation of cell proliferation GO:0008284 249 0.016
organ morphogenesis GO:0009887 75 0.016
purine ribonucleoside catabolic process GO:0046130 124 0.016
negative regulation of signaling GO:0023057 157 0.016
sodium ion transport GO:0006814 82 0.016
regulation of growth GO:0040008 105 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
Rat
negative regulation of cell communication GO:0010648 158 0.015
cell projection morphogenesis GO:0048858 123 0.015
positive regulation of biosynthetic process GO:0009891 319 0.015
ribonucleoside monophosphate metabolic process GO:0009161 88 0.015
peptidyl tyrosine phosphorylation GO:0018108 72 0.015
intracellular signal transduction GO:0035556 314 0.015
organelle localization GO:0051640 55 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.015
development of primary sexual characteristics GO:0045137 107 0.014
ribonucleotide biosynthetic process GO:0009260 85 0.014
divalent metal ion transport GO:0070838 132 0.014
regulation of synaptic transmission GO:0050804 141 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
cellular response to mechanical stimulus GO:0071260 48 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
actin filament based process GO:0030029 86 0.014
synaptic transmission GO:0007268 235 0.014
negative regulation of gene expression GO:0010629 199 0.014
cellular macromolecule localization GO:0070727 122 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
regulation of signal transduction GO:0009966 318 0.014
glial cell differentiation GO:0010001 65 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
cell type specific apoptotic process GO:0097285 134 0.014
negative regulation of cell death GO:0060548 229 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
monocarboxylic acid biosynthetic process GO:0072330 48 0.013
leukocyte activation GO:0045321 76 0.013
response to vitamin GO:0033273 131 0.013
vesicle localization GO:0051648 33 0.013
cell activation GO:0001775 97 0.013
regulation of synaptic plasticity GO:0048167 70 0.013
gonad development GO:0008406 104 0.013
cell migration GO:0016477 197 0.013
sex differentiation GO:0007548 113 0.013
multicellular organism reproduction GO:0032504 233 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
carboxylic acid transport GO:0046942 115 0.013
gliogenesis GO:0042063 93 0.013
sexual reproduction GO:0019953 148 0.013
regulation of dna metabolic process GO:0051052 60 0.013
protein transport GO:0015031 132 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
positive regulation of secretion GO:0051047 140 0.013
hormone secretion GO:0046879 115 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
gtp catabolic process GO:0006184 71 0.013
nucleotide catabolic process GO:0009166 139 0.013
protein maturation GO:0051604 68 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
neural crest cell development GO:0014032 2 0.012
regulation of cell growth GO:0001558 85 0.012
lipid biosynthetic process GO:0008610 128 0.012
regulation of cell motility GO:2000145 131 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
neural crest cell migration GO:0001755 1 0.012
blood vessel morphogenesis GO:0048514 58 0.012
organic anion transport GO:0015711 132 0.012
muscle structure development GO:0061061 87 0.012
fatty acid metabolic process GO:0006631 99 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
regulation of neuron projection development GO:0010975 161 0.012
nucleoside monophosphate metabolic process GO:0009123 93 0.012
salivary gland development GO:0007431 3 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
endocytosis GO:0006897 84 0.012
forebrain development GO:0030900 98 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
axon development GO:0061564 96 0.012
response to starvation GO:0042594 59 0.012
cation transport GO:0006812 382 0.012
multicellular organism growth GO:0035264 1 0.012
regulation of mapk cascade GO:0043408 116 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.011
regulation of catabolic process GO:0009894 113 0.011
actin filament depolymerization GO:0030042 3 0.011
tissue remodeling GO:0048771 40 0.011
dendrite development GO:0016358 72 0.011
axonogenesis GO:0007409 71 0.011
angiogenesis GO:0001525 53 0.011
mitotic dna damage checkpoint GO:0044773 1 0.011
negative regulation of peptidase activity GO:0010466 38 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
protein oligomerization GO:0051259 191 0.011
positive regulation of cellular component biogenesis GO:0044089 55 0.011
regulation of cytoskeleton organization GO:0051493 49 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
single organism reproductive process GO:0044702 297 0.011
carbohydrate biosynthetic process GO:0016051 42 0.011
epithelial cell differentiation GO:0030855 71 0.011
regulation of protein transport GO:0051223 68 0.011
dna integrity checkpoint GO:0031570 2 0.011
response to toxic substance GO:0009636 133 0.011
regulation of blood vessel size GO:0050880 89 0.011
anion transport GO:0006820 178 0.011
maintenance of location GO:0051235 17 0.011
negative regulation of protein modification process GO:0031400 52 0.011
regulation of transferase activity GO:0051338 123 0.011
glucan metabolic process GO:0044042 23 0.011
positive regulation of gene expression GO:0010628 244 0.011
liver development GO:0001889 90 0.011
immune system process GO:0002376 204 0.011
regulation of immune system process GO:0002682 123 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
regulation of hormone secretion GO:0046883 106 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
positive regulation of cytoskeleton organization GO:0051495 26 0.011
response to zinc ion GO:0010043 39 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
immune response GO:0006955 104 0.011
ion homeostasis GO:0050801 212 0.010
protein homotetramerization GO:0051289 25 0.010
lymphocyte activation involved in immune response GO:0002285 3 0.010
regulation of cell activation GO:0050865 50 0.010
cellular response to steroid hormone stimulus GO:0071383 93 0.010
development of primary male sexual characteristics GO:0046546 59 0.010
cellular protein complex assembly GO:0043623 44 0.010
muscle contraction GO:0006936 88 0.010
cellular response to alcohol GO:0097306 87 0.010
nucleoside triphosphate catabolic process GO:0009143 123 0.010
synaptic vesicle endocytosis GO:0048488 4 0.010
single organism intracellular transport GO:1902582 166 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010

Ckb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
nervous system disease DOID:863 0 0.049
disease of metabolism DOID:0014667 0 0.026
central nervous system disease DOID:331 0 0.015
inherited metabolic disorder DOID:655 0 0.014