Rattus norvegicus

0 known processes

Alx3

aristaless-like homeobox 3

Alx3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.162
response to biotic stimulus GO:0009607 226 0.151
response to other organism GO:0051707 220 0.149
programmed cell death GO:0012501 392 0.113
response to lipopolysaccharide GO:0032496 191 0.109
tissue development GO:0009888 252 0.106
rna biosynthetic process GO:0032774 380 0.103
inorganic cation transmembrane transport GO:0098662 202 0.103
response to bacterium GO:0009617 200 0.098
regulation of programmed cell death GO:0043067 341 0.094
response to external biotic stimulus GO:0043207 221 0.092
single organism reproductive process GO:0044702 297 0.083
oxoacid metabolic process GO:0043436 290 0.082
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.081
regulation of multicellular organismal development GO:2000026 376 0.079
reproductive structure development GO:0048608 128 0.078
inorganic ion transmembrane transport GO:0098660 229 0.077
cation transmembrane transport GO:0098655 263 0.076
regulation of cell proliferation GO:0042127 359 0.074
response to nutrient levels GO:0031667 370 0.069
apoptotic process GO:0006915 381 0.068
rna metabolic process GO:0016070 406 0.065
positive regulation of rna biosynthetic process GO:1902680 197 0.064
anion transport GO:0006820 178 0.062
positive regulation of cellular biosynthetic process GO:0031328 295 0.062
ion transmembrane transport GO:0034220 365 0.060
nitrogen compound transport GO:0071705 229 0.060
organic acid metabolic process GO:0006082 292 0.056
cell cell signaling GO:0007267 335 0.056
organic anion transport GO:0015711 132 0.055
nucleic acid templated transcription GO:0097659 379 0.054
single organism biosynthetic process GO:0044711 342 0.054
transcription dna templated GO:0006351 377 0.053
transmembrane transport GO:0055085 412 0.053
response to extracellular stimulus GO:0009991 380 0.052
transcription from rna polymerase ii promoter GO:0006366 252 0.052
lipid metabolic process GO:0006629 283 0.051
response to acid chemical GO:0001101 222 0.050
cellular lipid metabolic process GO:0044255 208 0.050
response to molecule of bacterial origin GO:0002237 194 0.048
reproductive process GO:0022414 372 0.048
cellular response to endogenous stimulus GO:0071495 377 0.047
epithelial cell proliferation GO:0050673 54 0.046
response to peptide hormone GO:0043434 278 0.045
carboxylic acid metabolic process GO:0019752 289 0.045
multicellular organism reproduction GO:0032504 233 0.045
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.045
regulation of transcription dna templated GO:0006355 374 0.044
growth GO:0040007 165 0.044
positive regulation of transcription dna templated GO:0045893 197 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.043
positive regulation of biosynthetic process GO:0009891 319 0.043
reproduction GO:0000003 245 0.041
cellular ketone metabolic process GO:0042180 51 0.040
positive regulation of gene expression GO:0010628 244 0.040
secretion GO:0046903 307 0.039
negative regulation of cellular biosynthetic process GO:0031327 161 0.039
response to nutrient GO:0007584 248 0.039
developmental process involved in reproduction GO:0003006 159 0.039
regulation of rna metabolic process GO:0051252 391 0.038
multicellular organismal reproductive process GO:0048609 233 0.038
metal ion transport GO:0030001 289 0.037
positive regulation of rna metabolic process GO:0051254 203 0.037
positive regulation of programmed cell death GO:0043068 157 0.036
response to oxygen levels GO:0070482 265 0.036
regulation of cellular ketone metabolic process GO:0010565 27 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.036
anatomical structure morphogenesis GO:0009653 298 0.036
reproductive system development GO:0061458 128 0.036
positive regulation of cell proliferation GO:0008284 249 0.036
positive regulation of cell communication GO:0010647 271 0.036
positive regulation of secretion GO:0051047 140 0.035
cellular response to stress GO:0033554 269 0.035
oxidation reduction process GO:0055114 304 0.035
regulation of apoptotic process GO:0042981 335 0.035
regulation of rna biosynthetic process GO:2001141 381 0.034
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.034
response to glucocorticoid GO:0051384 223 0.034
regulation of cell differentiation GO:0045595 320 0.034
negative regulation of metabolic process GO:0009892 331 0.033
lipid transport GO:0006869 61 0.033
regulation of cell development GO:0060284 263 0.033
central nervous system development GO:0007417 311 0.033
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.033
regulation of epithelial cell proliferation GO:0050678 49 0.033
monovalent inorganic cation transport GO:0015672 172 0.032
regulation of phosphate metabolic process GO:0019220 349 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.031
cation homeostasis GO:0055080 195 0.031
homeostatic process GO:0042592 331 0.031
positive regulation of protein metabolic process GO:0051247 178 0.031
negative regulation of programmed cell death GO:0043069 183 0.031
positive regulation of catalytic activity GO:0043085 184 0.031
response to wounding GO:0009611 254 0.031
metal ion homeostasis GO:0055065 186 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
response to monosaccharide GO:0034284 159 0.030
cellular amine metabolic process GO:0044106 38 0.030
response to peptide GO:1901652 292 0.030
fatty acid metabolic process GO:0006631 99 0.030
negative regulation of cell proliferation GO:0008285 119 0.030
anatomical structure formation involved in morphogenesis GO:0048646 83 0.030
carboxylic acid transport GO:0046942 115 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
steroid metabolic process GO:0008202 73 0.029
negative regulation of cell death GO:0060548 229 0.029
transmission of nerve impulse GO:0019226 42 0.029
response to ketone GO:1901654 182 0.029
cellular amino acid metabolic process GO:0006520 107 0.028
regulation of system process GO:0044057 208 0.028
response to estrogen GO:0043627 232 0.028
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.028
organic acid transport GO:0015849 116 0.028
circulatory system development GO:0072359 134 0.028
gland development GO:0048732 155 0.027
cellular response to organic cyclic compound GO:0071407 202 0.027
cardiovascular system development GO:0072358 134 0.027
cellular response to hormone stimulus GO:0032870 247 0.027
regulation of hormone levels GO:0010817 187 0.027
cellular component movement GO:0006928 248 0.027
neuron differentiation GO:0030182 368 0.026
multi organism reproductive process GO:0044703 262 0.025
cellular chemical homeostasis GO:0055082 247 0.025
carboxylic acid biosynthetic process GO:0046394 83 0.025
divalent inorganic cation transport GO:0072511 134 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.025
multi multicellular organism process GO:0044706 138 0.025
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.025
regulation of neurogenesis GO:0050767 247 0.025
neuron death GO:0070997 127 0.025
regulation of nervous system development GO:0051960 264 0.024
vesicle mediated transport GO:0016192 181 0.024
ion homeostasis GO:0050801 212 0.024
response to ethanol GO:0045471 162 0.024
neurological system process GO:0050877 219 0.024
cell adhesion GO:0007155 110 0.024
negative regulation of transcription dna templated GO:0045892 116 0.024
response to toxic substance GO:0009636 133 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
macromolecular complex assembly GO:0065003 273 0.023
aging GO:0007568 241 0.023
amine metabolic process GO:0009308 38 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
proteolysis GO:0006508 175 0.023
response to carbohydrate GO:0009743 183 0.023
intracellular signal transduction GO:0035556 314 0.023
regulation of molecular function GO:0065009 398 0.023
negative regulation of biosynthetic process GO:0009890 168 0.023
chemical homeostasis GO:0048878 292 0.023
leukocyte activation GO:0045321 76 0.022
negative regulation of apoptotic process GO:0043066 181 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
regulation of catalytic activity GO:0050790 304 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
cellular response to oxygen containing compound GO:1901701 386 0.022
secretion by cell GO:0032940 248 0.022
cell migration GO:0016477 197 0.021
response to alkaloid GO:0043279 132 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
establishment of tissue polarity GO:0007164 2 0.021
positive regulation of epithelial cell proliferation GO:0050679 32 0.021
single organism organelle organization GO:1902589 180 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
fatty acid oxidation GO:0019395 29 0.020
positive regulation of molecular function GO:0044093 230 0.020
sex differentiation GO:0007548 113 0.020
response to estradiol GO:0032355 164 0.020
cellular component assembly GO:0022607 360 0.020
multicellular organismal signaling GO:0035637 44 0.020
response to cytokine GO:0034097 215 0.020
regeneration GO:0031099 163 0.020
response to camp GO:0051591 91 0.020
neuronal action potential GO:0019228 35 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.020
positive regulation of developmental process GO:0051094 283 0.020
defense response GO:0006952 194 0.019
neuron projection development GO:0031175 273 0.019
muscle system process GO:0003012 115 0.019
nucleotide metabolic process GO:0009117 279 0.019
response to hypoxia GO:0001666 231 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
response to decreased oxygen levels GO:0036293 237 0.019
response to purine containing compound GO:0014074 126 0.019
response to corticosteroid GO:0031960 235 0.019
neuron development GO:0048666 286 0.018
positive regulation of nervous system development GO:0051962 178 0.018
protein complex assembly GO:0006461 263 0.018
response to inorganic substance GO:0010035 377 0.018
gamete generation GO:0007276 124 0.018
positive regulation of cellular component movement GO:0051272 102 0.018
regulation of protein metabolic process GO:0051246 289 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
positive regulation of signaling GO:0023056 270 0.018
cellular response to external stimulus GO:0071496 118 0.018
female pregnancy GO:0007565 122 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
axon ensheathment GO:0008366 40 0.018
negative regulation of cell differentiation GO:0045596 99 0.018
brain development GO:0007420 247 0.017
regulation of secretion by cell GO:1903530 208 0.017
response to metal ion GO:0010038 253 0.017
negative regulation of innate immune response GO:0045824 4 0.017
regulation of cellular localization GO:0060341 263 0.017
response to vitamin GO:0033273 131 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
cellular response to lipid GO:0071396 201 0.017
response to fatty acid GO:0070542 65 0.017
leukocyte cell cell adhesion GO:0007159 4 0.017
negative regulation of rna biosynthetic process GO:1902679 118 0.017
locomotion GO:0040011 237 0.017
myelination GO:0042552 39 0.017
immune response GO:0006955 104 0.017
response to ammonium ion GO:0060359 71 0.017
positive regulation of amine transport GO:0051954 26 0.017
positive regulation of cellular component organization GO:0051130 200 0.016
macromolecule localization GO:0033036 252 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
organ morphogenesis GO:0009887 75 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
regulation of peptide hormone secretion GO:0090276 80 0.016
regulation of peptide transport GO:0090087 87 0.016
response to oxidative stress GO:0006979 186 0.016
developmental growth GO:0048589 100 0.016
positive regulation of cell development GO:0010720 176 0.016
circulatory system process GO:0003013 183 0.016
cytosolic calcium ion homeostasis GO:0051480 140 0.016
regulation of secretion GO:0051046 224 0.015
positive regulation of signal transduction GO:0009967 175 0.015
cell projection morphogenesis GO:0048858 123 0.015
cell projection organization GO:0030030 302 0.015
regulation of nucleic acid templated transcription GO:1903506 380 0.015
sexual reproduction GO:0019953 148 0.015
gonad development GO:0008406 104 0.015
male sex differentiation GO:0046661 64 0.015
cellular response to steroid hormone stimulus GO:0071383 93 0.015
divalent metal ion transport GO:0070838 132 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
cellular response to cytokine stimulus GO:0071345 127 0.015
cellular response to mechanical stimulus GO:0071260 48 0.015
endothelial cell proliferation GO:0001935 20 0.015
monocarboxylic acid transport GO:0015718 52 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
lipid biosynthetic process GO:0008610 128 0.014
protein complex subunit organization GO:0071822 302 0.014
peptidyl tyrosine phosphorylation GO:0018108 72 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
response to gonadotropin GO:0034698 34 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
ensheathment of neurons GO:0007272 40 0.014
protein oligomerization GO:0051259 191 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
action potential GO:0001508 54 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
response to hexose GO:0009746 144 0.014
non canonical wnt signaling pathway GO:0035567 3 0.014
spermatogenesis GO:0007283 99 0.014
response to mechanical stimulus GO:0009612 134 0.014
response to insulin GO:0032868 133 0.014
regulation of peptide secretion GO:0002791 82 0.014
cellular component biogenesis GO:0044085 368 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
tube development GO:0035295 89 0.013
male gamete generation GO:0048232 99 0.013
regulation of cellular component organization GO:0051128 368 0.013
regulation of locomotion GO:0040012 148 0.013
localization of cell GO:0051674 202 0.013
organic acid biosynthetic process GO:0016053 83 0.013
peptide transport GO:0015833 97 0.013
regulation of protein modification process GO:0031399 194 0.013
regulation of signal transduction GO:0009966 318 0.013
cellular component morphogenesis GO:0032989 155 0.013
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.013
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
axis specification GO:0009798 4 0.013
ras protein signal transduction GO:0007265 29 0.013
fatty acid derivative metabolic process GO:1901568 38 0.013
regulation of synaptic transmission GO:0050804 141 0.013
morphogenesis of embryonic epithelium GO:0016331 3 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.013
regulation of mapk cascade GO:0043408 116 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
hormone metabolic process GO:0042445 69 0.013
establishment of planar polarity GO:0001736 1 0.013
regulation of neuron apoptotic process GO:0043523 83 0.013
response to growth factor GO:0070848 189 0.013
response to hyperoxia GO:0055093 45 0.013
cellular calcium ion homeostasis GO:0006874 160 0.012
regulation of growth GO:0040008 105 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
positive regulation of immune system process GO:0002684 90 0.012
regulation of cell migration GO:0030334 128 0.012
epithelium development GO:0060429 96 0.012
cell motility GO:0048870 202 0.012
calcium ion transport GO:0006816 131 0.012
protein complex biogenesis GO:0070271 263 0.012
cellular amide metabolic process GO:0043603 44 0.012
liver development GO:0001889 90 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
regulation of immune system process GO:0002682 123 0.012
icosanoid metabolic process GO:0006690 38 0.012
endocytosis GO:0006897 84 0.012
cellular cation homeostasis GO:0030003 180 0.012
organic hydroxy compound transport GO:0015850 77 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
negative regulation of molecular function GO:0044092 133 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
single organism intracellular transport GO:1902582 166 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
protein phosphorylation GO:0006468 345 0.012
maternal process involved in female pregnancy GO:0060135 38 0.012
peptidyl amino acid modification GO:0018193 126 0.012
regulation of membrane potential GO:0042391 110 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
amide transport GO:0042886 105 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
regulation of insulin secretion GO:0050796 65 0.011
development of primary sexual characteristics GO:0045137 107 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
intestinal absorption GO:0050892 3 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
establishment of protein localization GO:0045184 141 0.011
response to nicotine GO:0035094 51 0.011
purine containing compound metabolic process GO:0072521 253 0.011
cellular catabolic process GO:0044248 295 0.011
lipid localization GO:0010876 62 0.011
sensory perception of bitter taste GO:0050913 4 0.011
sequestering of calcium ion GO:0051208 8 0.011
cellular response to acid chemical GO:0071229 75 0.011
cellular homeostasis GO:0019725 252 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
response to increased oxygen levels GO:0036296 45 0.011
hepatocyte proliferation GO:0072574 3 0.011
response to glucose GO:0009749 136 0.011
cellular response to glucocorticoid stimulus GO:0071385 68 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
regulation of ion homeostasis GO:2000021 63 0.011
glial cell differentiation GO:0010001 65 0.011
positive regulation of transferase activity GO:0051347 81 0.011
cellular response to reactive oxygen species GO:0034614 55 0.011
cellular hormone metabolic process GO:0034754 49 0.011
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.011
cellular response to biotic stimulus GO:0071216 59 0.011
response to activity GO:0014823 73 0.011
spindle organization GO:0007051 2 0.011
heart development GO:0007507 72 0.011
immune system process GO:0002376 204 0.011
organelle organization GO:0006996 266 0.011
wound healing GO:0042060 122 0.010
ribonucleotide metabolic process GO:0009259 231 0.010
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.010
hormone secretion GO:0046879 115 0.010
heart morphogenesis GO:0003007 3 0.010
natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002420 1 0.010
positive regulation of ion transport GO:0043270 94 0.010
regulation of establishment of planar polarity GO:0090175 2 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
lipid storage GO:0019915 1 0.010
organ regeneration GO:0031100 101 0.010
positive regulation of phosphate metabolic process GO:0045937 262 0.010
hormone transport GO:0009914 121 0.010
monocarboxylic acid biosynthetic process GO:0072330 48 0.010
organophosphate metabolic process GO:0019637 370 0.010
anterior posterior pattern specification GO:0009952 1 0.010
respiratory system development GO:0060541 45 0.010
diterpenoid metabolic process GO:0016101 33 0.010

Alx3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038
sensory system disease DOID:0050155 0 0.014
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.011