Rattus norvegicus

0 known processes

Alx4

ALX homeobox 4

Alx4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to oxygen containing compound GO:1901701 386 0.040
response to extracellular stimulus GO:0009991 380 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.040
Mouse
response to inorganic substance GO:0010035 377 0.039
response to nutrient levels GO:0031667 370 0.038
oxoacid metabolic process GO:0043436 290 0.037
central nervous system development GO:0007417 311 0.036
regulation of cell proliferation GO:0042127 359 0.036
homeostatic process GO:0042592 331 0.036
response to oxygen levels GO:0070482 265 0.034
programmed cell death GO:0012501 392 0.034
Mouse
reproductive process GO:0022414 372 0.033
carboxylic acid metabolic process GO:0019752 289 0.033
response to peptide GO:1901652 292 0.033
rna biosynthetic process GO:0032774 380 0.033
Mouse
regulation of nucleic acid templated transcription GO:1903506 380 0.032
Mouse Rat
cellular homeostasis GO:0019725 252 0.032
protein phosphorylation GO:0006468 345 0.032
single organism reproductive process GO:0044702 297 0.032
regulation of rna metabolic process GO:0051252 391 0.032
Mouse Rat
cellular chemical homeostasis GO:0055082 247 0.032
transmembrane transport GO:0055085 412 0.031
cellular component biogenesis GO:0044085 368 0.031
regulation of programmed cell death GO:0043067 341 0.031
Mouse
organic acid metabolic process GO:0006082 292 0.031
transcription dna templated GO:0006351 377 0.030
Mouse
cellular component assembly GO:0022607 360 0.030
regulation of molecular function GO:0065009 398 0.030
neuron differentiation GO:0030182 368 0.030
chemical homeostasis GO:0048878 292 0.030
regulation of transcription dna templated GO:0006355 374 0.030
Mouse Rat
carbohydrate derivative metabolic process GO:1901135 346 0.030
regulation of phosphate metabolic process GO:0019220 349 0.030
cellular cation homeostasis GO:0030003 180 0.029
secretion GO:0046903 307 0.029
rna metabolic process GO:0016070 406 0.029
Mouse
positive regulation of biosynthetic process GO:0009891 319 0.029
Mouse
cell cell signaling GO:0007267 335 0.029
response to decreased oxygen levels GO:0036293 237 0.029
cation transport GO:0006812 382 0.029
regulation of apoptotic process GO:0042981 335 0.029
Mouse
organophosphate metabolic process GO:0019637 370 0.028
response to hypoxia GO:0001666 231 0.027
apoptotic process GO:0006915 381 0.027
Mouse
response to corticosteroid GO:0031960 235 0.027
nucleic acid templated transcription GO:0097659 379 0.027
Mouse
response to estrogen GO:0043627 232 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
regulation of multicellular organismal development GO:2000026 376 0.027
regulation of rna biosynthetic process GO:2001141 381 0.027
Mouse Rat
negative regulation of metabolic process GO:0009892 331 0.027
multi organism reproductive process GO:0044703 262 0.027
regulation of catalytic activity GO:0050790 304 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
ion transmembrane transport GO:0034220 365 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
amine metabolic process GO:0009308 38 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
Mouse
cellular amine metabolic process GO:0044106 38 0.026
response to metal ion GO:0010038 253 0.026
cellular response to stress GO:0033554 269 0.026
neurological system process GO:0050877 219 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
head development GO:0060322 247 0.025
response to peptide hormone GO:0043434 278 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
positive regulation of signaling GO:0023056 270 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
intracellular signal transduction GO:0035556 314 0.025
cellular ketone metabolic process GO:0042180 51 0.025
brain development GO:0007420 247 0.025
transcription from rna polymerase ii promoter GO:0006366 252 0.025
Mouse
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
Mouse
positive regulation of response to stimulus GO:0048584 285 0.024
cellular ion homeostasis GO:0006873 184 0.024
cellular component movement GO:0006928 248 0.024
regulation of cell differentiation GO:0045595 320 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
nitrogen compound transport GO:0071705 229 0.024
regulation of secretion GO:0051046 224 0.024
protein complex assembly GO:0006461 263 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
Mouse
nucleoside phosphate metabolic process GO:0006753 283 0.024
reproduction GO:0000003 245 0.023
secretion by cell GO:0032940 248 0.023
negative regulation of cell death GO:0060548 229 0.023
cell projection organization GO:0030030 302 0.023
ion homeostasis GO:0050801 212 0.023
response to other organism GO:0051707 220 0.023
response to acid chemical GO:0001101 222 0.023
positive regulation of molecular function GO:0044093 230 0.023
metal ion homeostasis GO:0055065 186 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
single organism biosynthetic process GO:0044711 342 0.023
positive regulation of gene expression GO:0010628 244 0.023
Mouse
cation homeostasis GO:0055080 195 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
macromolecular complex assembly GO:0065003 273 0.023
regulation of protein metabolic process GO:0051246 289 0.023
positive regulation of transport GO:0051050 245 0.022
protein complex subunit organization GO:0071822 302 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
regulation of secretion by cell GO:1903530 208 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
metal ion transport GO:0030001 289 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
response to wounding GO:0009611 254 0.022
regulation of cellular component organization GO:0051128 368 0.022
cellular metal ion homeostasis GO:0006875 172 0.022
neuron projection development GO:0031175 273 0.022
lipid metabolic process GO:0006629 283 0.022
response to bacterium GO:0009617 200 0.022
multicellular organism reproduction GO:0032504 233 0.022
regulation of phosphorylation GO:0042325 248 0.022
cellular divalent inorganic cation homeostasis GO:0072503 162 0.022
response to estradiol GO:0032355 164 0.022
blood circulation GO:0008015 183 0.021
positive regulation of cell communication GO:0010647 271 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
response to nutrient GO:0007584 248 0.021
response to carbohydrate GO:0009743 183 0.021
circulatory system process GO:0003013 183 0.021
positive regulation of developmental process GO:0051094 283 0.021
regulation of signal transduction GO:0009966 318 0.021
cellular calcium ion homeostasis GO:0006874 160 0.021
regulation of cellular localization GO:0060341 263 0.021
g protein coupled receptor signaling pathway GO:0007186 242 0.021
catabolic process GO:0009056 351 0.021
aging GO:0007568 241 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
protein complex biogenesis GO:0070271 263 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
Mouse
calcium ion homeostasis GO:0055074 162 0.020
localization of cell GO:0051674 202 0.020
synaptic transmission GO:0007268 235 0.020
response to growth factor GO:0070848 189 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
regulation of hormone levels GO:0010817 187 0.020
regulation of system process GO:0044057 208 0.020
response to biotic stimulus GO:0009607 226 0.020
organelle organization GO:0006996 266 0.020
response to external biotic stimulus GO:0043207 221 0.020
purine containing compound metabolic process GO:0072521 253 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
Mouse
regulation of protein phosphorylation GO:0001932 183 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
cellular response to organonitrogen compound GO:0071417 197 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
Mouse
locomotion GO:0040011 237 0.019
response to cytokine GO:0034097 215 0.019
response to glucocorticoid GO:0051384 223 0.019
nucleotide metabolic process GO:0009117 279 0.019
response to lipopolysaccharide GO:0032496 191 0.019
anion transport GO:0006820 178 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
tissue development GO:0009888 252 0.019
Human
ribonucleotide metabolic process GO:0009259 231 0.019
regulation of ion transport GO:0043269 245 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
regulation of nervous system development GO:0051960 264 0.019
cellular response to lipid GO:0071396 201 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.019
response to ketone GO:1901654 182 0.019
macromolecule localization GO:0033036 252 0.019
regulation of neurogenesis GO:0050767 247 0.019
regulation of protein modification process GO:0031399 194 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
developmental process involved in reproduction GO:0003006 159 0.018
regeneration GO:0031099 163 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
response to monosaccharide GO:0034284 159 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
anterior posterior pattern specification GO:0009952 1 0.018
Mouse
cellular catabolic process GO:0044248 295 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
gland development GO:0048732 155 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
Mouse
negative regulation of apoptotic process GO:0043066 181 0.018
protein oligomerization GO:0051259 191 0.018
neuron development GO:0048666 286 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
Mouse
regulation of intracellular signal transduction GO:1902531 218 0.017
response to hexose GO:0009746 144 0.017
defense response GO:0006952 194 0.017
cation transmembrane transport GO:0098655 263 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
regulation of cell development GO:0060284 263 0.017
cell migration GO:0016477 197 0.017
inorganic ion transmembrane transport GO:0098660 229 0.017
response to oxidative stress GO:0006979 186 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
hormone transport GO:0009914 121 0.017
sexual reproduction GO:0019953 148 0.016
divalent inorganic cation transport GO:0072511 134 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
Mouse
positive regulation of phosphorylation GO:0042327 177 0.016
positive regulation of cell death GO:0010942 184 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
divalent metal ion transport GO:0070838 132 0.016
signal release GO:0023061 145 0.016
single organism catabolic process GO:0044712 283 0.016
cellular response to peptide GO:1901653 133 0.016
behavior GO:0007610 205 0.016
carbohydrate metabolic process GO:0005975 130 0.016
regulation of anatomical structure size GO:0090066 135 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
cell motility GO:0048870 202 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
regulation of neuron differentiation GO:0045664 208 0.016
response to alkaloid GO:0043279 132 0.016
response to glucose GO:0009749 136 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
regulation of hormone secretion GO:0046883 106 0.016
regulation of locomotion GO:0040012 148 0.016
muscle system process GO:0003012 115 0.015
hormone secretion GO:0046879 115 0.015
axis specification GO:0009798 4 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
organic substance catabolic process GO:1901575 316 0.015
regulation of membrane potential GO:0042391 110 0.015
heart morphogenesis GO:0003007 3 0.015
response to ethanol GO:0045471 162 0.015
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.015
response to toxic substance GO:0009636 133 0.015
growth GO:0040007 165 0.015
negative regulation of cell communication GO:0010648 158 0.015
intracellular transport GO:0046907 185 0.015
negative regulation of transport GO:0051051 136 0.015
regulation of hydrolase activity GO:0051336 143 0.015
regulation of cellular component movement GO:0051270 150 0.014
response to mechanical stimulus GO:0009612 134 0.014
heterocycle catabolic process GO:0046700 167 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
immune system process GO:0002376 204 0.014
cellular lipid metabolic process GO:0044255 208 0.014
positive regulation of secretion GO:0051047 140 0.014
proteolysis GO:0006508 175 0.014
amide transport GO:0042886 105 0.014
calcium ion transport GO:0006816 131 0.014
negative regulation of signaling GO:0023057 157 0.014
vesicle mediated transport GO:0016192 181 0.014
nucleoside metabolic process GO:0009116 179 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
ras protein signal transduction GO:0007265 29 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
regulation of blood circulation GO:1903522 110 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
regulation of cell projection organization GO:0031344 175 0.014
organophosphate biosynthetic process GO:0090407 143 0.013
single organism intracellular transport GO:1902582 166 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
organic anion transport GO:0015711 132 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
forebrain development GO:0030900 98 0.013
negative regulation of gene expression GO:0010629 199 0.013
positive regulation of signal transduction GO:0009967 175 0.013
regulation of cell motility GO:2000145 131 0.013
gastrulation GO:0007369 2 0.013
regulation of metal ion transport GO:0010959 118 0.013
response to reactive oxygen species GO:0000302 120 0.013
cellular component morphogenesis GO:0032989 155 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
positive regulation of cell development GO:0010720 176 0.013
organic acid transport GO:0015849 116 0.013
female pregnancy GO:0007565 122 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
gamete generation GO:0007276 124 0.013
organ regeneration GO:0031100 101 0.013
regulation of synaptic transmission GO:0050804 141 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
positive regulation of protein modification process GO:0031401 142 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
circulatory system development GO:0072359 134 0.013
cardiovascular system development GO:0072358 134 0.013
reproductive system development GO:0061458 128 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
oxidation reduction process GO:0055114 304 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
regulation of cell migration GO:0030334 128 0.013
regulation of homeostatic process GO:0032844 101 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
positive regulation of nervous system development GO:0051962 178 0.013
regulation of neuron projection development GO:0010975 161 0.012
single organism organelle organization GO:1902589 180 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
mapk cascade GO:0000165 140 0.012
inflammatory response GO:0006954 150 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
response to vitamin GO:0033273 131 0.012
response to radiation GO:0009314 137 0.012
cell type specific apoptotic process GO:0097285 134 0.012
rhythmic process GO:0048511 156 0.012
response to camp GO:0051591 91 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
regulation of body fluid levels GO:0050878 90 0.012
response to purine containing compound GO:0014074 126 0.012
single organism behavior GO:0044708 130 0.012
organophosphate catabolic process GO:0046434 148 0.012
regulation of transferase activity GO:0051338 123 0.012
reproductive structure development GO:0048608 128 0.012
transmission of nerve impulse GO:0019226 42 0.012
muscle cell proliferation GO:0033002 84 0.012
regulation of blood vessel size GO:0050880 89 0.012
protein localization GO:0008104 191 0.012
peptide transport GO:0015833 97 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
small molecule biosynthetic process GO:0044283 124 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
multi multicellular organism process GO:0044706 138 0.012
eye morphogenesis GO:0048592 4 0.012
carboxylic acid transport GO:0046942 115 0.012
vascular process in circulatory system GO:0003018 96 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
muscle contraction GO:0006936 88 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
negative regulation of innate immune response GO:0045824 4 0.012
cellular response to external stimulus GO:0071496 118 0.012
negative regulation of molecular function GO:0044092 133 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
response to insulin GO:0032868 133 0.012
embryonic pattern specification GO:0009880 1 0.011
regulation of tube size GO:0035150 89 0.011
regulation of kinase activity GO:0043549 117 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
spermatogenesis GO:0007283 99 0.011
multicellular organismal signaling GO:0035637 44 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
cell morphogenesis GO:0000902 142 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
regulation of mapk cascade GO:0043408 116 0.011
action potential GO:0001508 54 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
male gamete generation GO:0048232 99 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
cell growth GO:0016049 104 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
nucleotide catabolic process GO:0009166 139 0.011
regulation of neuron death GO:1901214 115 0.011
smooth muscle cell proliferation GO:0048659 77 0.011
lipid storage GO:0019915 1 0.011
dna metabolic process GO:0006259 96 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
response to organophosphorus GO:0046683 102 0.011
peptide hormone secretion GO:0030072 84 0.011
neuron death GO:0070997 127 0.011
sequestering of calcium ion GO:0051208 8 0.011
cellular response to alcohol GO:0097306 87 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
sex differentiation GO:0007548 113 0.011
sequestering of metal ion GO:0051238 9 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
positive regulation of ion transport GO:0043270 94 0.011
dephosphorylation GO:0016311 98 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
peptide secretion GO:0002790 86 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
purine containing compound catabolic process GO:0072523 138 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
cell activation GO:0001775 97 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
cytoplasmic transport GO:0016482 115 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
regulation of peptide secretion GO:0002791 82 0.010
regulation of muscle system process GO:0090257 79 0.010
appendage morphogenesis GO:0035107 4 0.010
Mouse
regulation of smooth muscle cell proliferation GO:0048660 75 0.010
regulation of immune system process GO:0002682 123 0.010
actin filament based process GO:0030029 86 0.010
wound healing GO:0042060 122 0.010
response to hydrogen peroxide GO:0042542 89 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
neuronal action potential GO:0019228 35 0.010
sensory perception GO:0007600 101 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
regulation of peptide transport GO:0090087 87 0.010
positive regulation of locomotion GO:0040017 102 0.010
salivary gland development GO:0007431 3 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
lipid biosynthetic process GO:0008610 128 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
limb morphogenesis GO:0035108 4 0.010
Mouse
maintenance of location GO:0051235 17 0.010
chromosome segregation GO:0007059 2 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
regulation of catabolic process GO:0009894 113 0.010
protein homooligomerization GO:0051260 91 0.010
immune response GO:0006955 104 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
regulation of protein kinase activity GO:0045859 105 0.010
regulation of peptide hormone secretion GO:0090276 80 0.010
multicellular organism growth GO:0035264 1 0.010

Alx4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
musculoskeletal system disease DOID:17 0 0.022
sensory system disease DOID:0050155 0 0.019
retinal disease DOID:5679 0 0.016
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
disease of metabolism DOID:0014667 0 0.015
cardiovascular system disease DOID:1287 0 0.013
connective tissue disease DOID:65 0 0.011
central nervous system disease DOID:331 0 0.010
muscular disease DOID:0080000 0 0.010