Rattus norvegicus

0 known processes

Lims2

LIM and senescent cell antigen like domains 2

Lims2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of apoptotic process GO:0042981 335 0.154
Mouse
regulation of protein metabolic process GO:0051246 289 0.135
regulation of catalytic activity GO:0050790 304 0.121
positive regulation of phosphorus metabolic process GO:0010562 262 0.120
regulation of molecular function GO:0065009 398 0.118
apoptotic process GO:0006915 381 0.100
Mouse
intracellular signal transduction GO:0035556 314 0.096
Zebrafish
blood circulation GO:0008015 183 0.095
Zebrafish
reproductive process GO:0022414 372 0.092
single organism biosynthetic process GO:0044711 342 0.092
regulation of signal transduction GO:0009966 318 0.088
Zebrafish Mouse
regulation of cell proliferation GO:0042127 359 0.082
Mouse
catabolic process GO:0009056 351 0.082
positive regulation of signal transduction GO:0009967 175 0.076
Mouse
organic substance catabolic process GO:1901575 316 0.071
regulation of cellular protein metabolic process GO:0032268 267 0.071
regulation of phosphorus metabolic process GO:0051174 349 0.069
programmed cell death GO:0012501 392 0.068
Mouse
regulation of phosphorylation GO:0042325 248 0.067
single organism catabolic process GO:0044712 283 0.063
cellular catabolic process GO:0044248 295 0.061
regulation of phosphate metabolic process GO:0019220 349 0.061
neuron differentiation GO:0030182 368 0.056
positive regulation of biosynthetic process GO:0009891 319 0.055
response to decreased oxygen levels GO:0036293 237 0.054
circulatory system process GO:0003013 183 0.052
Zebrafish
negative regulation of metabolic process GO:0009892 331 0.050
positive regulation of protein metabolic process GO:0051247 178 0.050
proteolysis GO:0006508 175 0.049
regulation of intracellular signal transduction GO:1902531 218 0.048
Zebrafish
regulation of cell development GO:0060284 263 0.048
regulation of cellular component organization GO:0051128 368 0.048
positive regulation of programmed cell death GO:0043068 157 0.048
positive regulation of apoptotic process GO:0043065 154 0.045
regulation of protein modification process GO:0031399 194 0.044
negative regulation of cell communication GO:0010648 158 0.044
regulation of hydrolase activity GO:0051336 143 0.043
neurological system process GO:0050877 219 0.043
positive regulation of cell communication GO:0010647 271 0.043
Mouse
negative regulation of response to stimulus GO:0048585 155 0.043
small gtpase mediated signal transduction GO:0007264 36 0.043
cellular lipid metabolic process GO:0044255 208 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
cellular chemical homeostasis GO:0055082 247 0.041
metal ion homeostasis GO:0055065 186 0.040
purine containing compound metabolic process GO:0072521 253 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.039
protein phosphorylation GO:0006468 345 0.039
regulation of system process GO:0044057 208 0.039
response to inorganic substance GO:0010035 377 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
positive regulation of molecular function GO:0044093 230 0.039
neuron development GO:0048666 286 0.038
positive regulation of protein modification process GO:0031401 142 0.037
cellular amino acid metabolic process GO:0006520 107 0.037
locomotion GO:0040011 237 0.037
oxoacid metabolic process GO:0043436 290 0.037
cell cell signaling GO:0007267 335 0.037
positive regulation of developmental process GO:0051094 283 0.036
ribose phosphate metabolic process GO:0019693 235 0.036
negative regulation of signaling GO:0023057 157 0.035
negative regulation of programmed cell death GO:0043069 183 0.035
Mouse
sensory perception of pain GO:0019233 73 0.035
anatomical structure morphogenesis GO:0009653 298 0.034
Mouse
regulation of response to stress GO:0080134 126 0.034
secretion GO:0046903 307 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
positive regulation of phosphate metabolic process GO:0045937 262 0.033
organonitrogen compound biosynthetic process GO:1901566 167 0.032
response to hypoxia GO:0001666 231 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
organophosphate metabolic process GO:0019637 370 0.032
regeneration GO:0031099 163 0.032
positive regulation of cell death GO:0010942 184 0.031
neuron projection development GO:0031175 273 0.031
negative regulation of protein metabolic process GO:0051248 114 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.031
regulation of cell migration GO:0030334 128 0.031
response to extracellular stimulus GO:0009991 380 0.031
response to wounding GO:0009611 254 0.031
response to oxygen levels GO:0070482 265 0.031
negative regulation of cellular metabolic process GO:0031324 281 0.030
positive regulation of catalytic activity GO:0043085 184 0.030
regulation of protein phosphorylation GO:0001932 183 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.030
cellular amine metabolic process GO:0044106 38 0.030
vascular process in circulatory system GO:0003018 96 0.030
carboxylic acid metabolic process GO:0019752 289 0.029
cell projection organization GO:0030030 302 0.029
regulation of programmed cell death GO:0043067 341 0.029
Mouse
positive regulation of cellular protein metabolic process GO:0032270 167 0.029
vesicle mediated transport GO:0016192 181 0.029
inorganic cation transmembrane transport GO:0098662 202 0.029
positive regulation of intracellular signal transduction GO:1902533 138 0.029
wound healing GO:0042060 122 0.029
ras protein signal transduction GO:0007265 29 0.029
cellular metal ion homeostasis GO:0006875 172 0.028
monovalent inorganic cation transport GO:0015672 172 0.028
cell migration GO:0016477 197 0.028
amine metabolic process GO:0009308 38 0.028
regulation of mapk cascade GO:0043408 116 0.027
central nervous system development GO:0007417 311 0.027
aging GO:0007568 241 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
Mouse
positive regulation of cell proliferation GO:0008284 249 0.027
cellular component assembly GO:0022607 360 0.027
Rat
single organism reproductive process GO:0044702 297 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
cellular divalent inorganic cation homeostasis GO:0072503 162 0.027
cellular homeostasis GO:0019725 252 0.027
liver development GO:0001889 90 0.026
Mouse
muscle cell proliferation GO:0033002 84 0.026
tissue development GO:0009888 252 0.026
protein complex subunit organization GO:0071822 302 0.026
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.026
response to peptide GO:1901652 292 0.026
response to nutrient levels GO:0031667 370 0.026
carbohydrate derivative biosynthetic process GO:1901137 124 0.025
macromolecule localization GO:0033036 252 0.025
behavior GO:0007610 205 0.025
positive regulation of transport GO:0051050 245 0.025
purine ribonucleoside metabolic process GO:0046128 168 0.025
negative regulation of molecular function GO:0044092 133 0.025
gastrulation GO:0007369 2 0.025
cation transport GO:0006812 382 0.025
biological adhesion GO:0022610 110 0.024
Mouse
multi multicellular organism process GO:0044706 138 0.024
organic acid metabolic process GO:0006082 292 0.024
response to carbohydrate GO:0009743 183 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
negative regulation of apoptotic process GO:0043066 181 0.024
Mouse
positive regulation of cell development GO:0010720 176 0.024
localization of cell GO:0051674 202 0.024
regulation of transferase activity GO:0051338 123 0.024
cellular response to endogenous stimulus GO:0071495 377 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
organonitrogen compound catabolic process GO:1901565 179 0.023
positive regulation of signaling GO:0023056 270 0.022
Mouse
cellular calcium ion homeostasis GO:0006874 160 0.022
positive regulation of mapk cascade GO:0043410 92 0.022
metal ion transport GO:0030001 289 0.022
positive regulation of protein phosphorylation GO:0001934 135 0.021
response to metal ion GO:0010038 253 0.021
sensory perception GO:0007600 101 0.021
ion homeostasis GO:0050801 212 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
regulation of kinase activity GO:0043549 117 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.021
regulation of anatomical structure size GO:0090066 135 0.021
positive regulation of transferase activity GO:0051347 81 0.021
nucleotide metabolic process GO:0009117 279 0.021
macromolecular complex assembly GO:0065003 273 0.020
Rat
regulation of cell differentiation GO:0045595 320 0.020
multi organism reproductive process GO:0044703 262 0.020
nucleoside phosphate biosynthetic process GO:1901293 102 0.020
brain development GO:0007420 247 0.020
regulation of phagocytosis engulfment GO:0060099 4 0.020
establishment of protein localization GO:0045184 141 0.020
regulation of tube size GO:0035150 89 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
multicellular organismal signaling GO:0035637 44 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
protein complex biogenesis GO:0070271 263 0.020
Rat
response to ketone GO:1901654 182 0.019
positive regulation of protein kinase activity GO:0045860 73 0.019
circulatory system development GO:0072359 134 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
Rat
organic hydroxy compound metabolic process GO:1901615 115 0.019
homeostatic process GO:0042592 331 0.019
regulation of neuron death GO:1901214 115 0.019
intracellular transport GO:0046907 185 0.019
fatty acid metabolic process GO:0006631 99 0.019
cell cell junction organization GO:0045216 20 0.019
Mouse
g protein coupled receptor signaling pathway GO:0007186 242 0.019
carbohydrate metabolic process GO:0005975 130 0.019
calcium ion homeostasis GO:0055074 162 0.019
carbohydrate derivative catabolic process GO:1901136 147 0.019
transmission of nerve impulse GO:0019226 42 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.019
protein complex assembly GO:0006461 263 0.018
Rat
regulation of cell growth GO:0001558 85 0.018
regulation of secretion GO:0051046 224 0.018
regulation of cell projection organization GO:0031344 175 0.018
multicellular organism reproduction GO:0032504 233 0.018
negative regulation of catalytic activity GO:0043086 103 0.018
cellular component biogenesis GO:0044085 368 0.018
Rat
reproduction GO:0000003 245 0.018
response to organophosphorus GO:0046683 102 0.018
regulation of defense response GO:0031347 68 0.018
protein localization GO:0008104 191 0.018
cellular ion homeostasis GO:0006873 184 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
Mouse
regulation of rna metabolic process GO:0051252 391 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
response to peptide hormone GO:0043434 278 0.018
regulation of blood vessel size GO:0050880 89 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
cell adhesion GO:0007155 110 0.018
Mouse
nucleoside phosphate metabolic process GO:0006753 283 0.017
response to tumor necrosis factor GO:0034612 56 0.017
response to growth factor GO:0070848 189 0.017
nitrogen compound transport GO:0071705 229 0.017
regulation of canonical wnt signaling pathway GO:0060828 4 0.017
unsaturated fatty acid metabolic process GO:0033559 39 0.017
muscle contraction GO:0006936 88 0.017
muscle system process GO:0003012 115 0.017
chemical homeostasis GO:0048878 292 0.017
lipid metabolic process GO:0006629 283 0.017
peptide secretion GO:0002790 86 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
response to oxidative stress GO:0006979 186 0.017
regulation of multicellular organismal development GO:2000026 376 0.017
Mouse
cellular ketone metabolic process GO:0042180 51 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
positive regulation of phagocytosis engulfment GO:0060100 4 0.017
purine nucleotide catabolic process GO:0006195 136 0.017
formation of primary germ layer GO:0001704 1 0.017
regulation of small gtpase mediated signal transduction GO:0051056 48 0.017
negative regulation of developmental process GO:0051093 125 0.017
Mouse
positive regulation of kinase activity GO:0033674 77 0.017
regulation of secretion by cell GO:1903530 208 0.017
organelle organization GO:0006996 266 0.017
defense response GO:0006952 194 0.016
regulation of blood pressure GO:0008217 83 0.016
cellular response to stress GO:0033554 269 0.016
heart morphogenesis GO:0003007 3 0.016
nucleoside catabolic process GO:0009164 126 0.016
hepaticobiliary system development GO:0061008 90 0.016
Mouse
response to hydrogen peroxide GO:0042542 89 0.016
neuronal action potential GO:0019228 35 0.016
regulation of neurogenesis GO:0050767 247 0.016
actin filament based process GO:0030029 86 0.016
regulation of proteolysis GO:0030162 66 0.016
regulation of g0 to g1 transition GO:0070316 3 0.016
protein maturation GO:0051604 68 0.016
regulation of blood circulation GO:1903522 110 0.016
nucleoside metabolic process GO:0009116 179 0.016
cation transmembrane transport GO:0098655 263 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
positive regulation of gene expression GO:0010628 244 0.016
potassium ion transport GO:0006813 97 0.016
cellular component movement GO:0006928 248 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
organic cyclic compound catabolic process GO:1901361 175 0.015
response to nutrient GO:0007584 248 0.015
regulation of proteasomal protein catabolic process GO:0061136 4 0.015
rna biosynthetic process GO:0032774 380 0.015
head development GO:0060322 247 0.015
sodium ion transport GO:0006814 82 0.015
aromatic compound catabolic process GO:0019439 168 0.015
regulation of membrane potential GO:0042391 110 0.015
mapk cascade GO:0000165 140 0.015
smooth muscle cell proliferation GO:0048659 77 0.015
regulation of nervous system development GO:0051960 264 0.015
positive regulation of cell motility GO:2000147 97 0.015
ion transmembrane transport GO:0034220 365 0.015
epithelium development GO:0060429 96 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
positive regulation of cell migration GO:0030335 96 0.015
growth GO:0040007 165 0.015
positive regulation of cellular component movement GO:0051272 102 0.015
anatomical structure formation involved in morphogenesis GO:0048646 83 0.015
regulation of cell motility GO:2000145 131 0.014
neuron death GO:0070997 127 0.014
peptide metabolic process GO:0006518 32 0.014
protein transport GO:0015031 132 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
mesoderm development GO:0007498 2 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
cellular cation homeostasis GO:0030003 180 0.014
response to purine containing compound GO:0014074 126 0.014
regulation of muscle system process GO:0090257 79 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
divalent metal ion transport GO:0070838 132 0.014
heterocycle catabolic process GO:0046700 167 0.014
cardiovascular system development GO:0072358 134 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
reactive nitrogen species metabolic process GO:2001057 1 0.014
hemostasis GO:0007599 26 0.014
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.014
cellular protein localization GO:0034613 122 0.014
cation homeostasis GO:0055080 195 0.014
regulation of body fluid levels GO:0050878 90 0.014
renal system development GO:0072001 67 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
synaptic transmission GO:0007268 235 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
membrane organization GO:0061024 94 0.014
response to bacterium GO:0009617 200 0.014
lipid catabolic process GO:0016042 46 0.014
kidney development GO:0001822 67 0.014
response to reactive oxygen species GO:0000302 120 0.013
regulation of neurological system process GO:0031644 43 0.013
ossification GO:0001503 70 0.013
regulation of cellular localization GO:0060341 263 0.013
response to corticosteroid GO:0031960 235 0.013
response to activity GO:0014823 73 0.013
divalent inorganic cation transport GO:0072511 134 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
regulation of hormone levels GO:0010817 187 0.013
regulation of cellular component movement GO:0051270 150 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
regulation of protein kinase activity GO:0045859 105 0.013
single organism intracellular transport GO:1902582 166 0.013
regulation of response to external stimulus GO:0032101 106 0.013
protein oligomerization GO:0051259 191 0.013
Rat
negative regulation of cell death GO:0060548 229 0.013
Mouse
positive regulation of response to external stimulus GO:0032103 51 0.013
sodium ion transmembrane transport GO:0035725 67 0.013
positive regulation of hydrolase activity GO:0051345 86 0.013
long chain fatty acid metabolic process GO:0001676 32 0.013
regulation of response to wounding GO:1903034 69 0.013
hormone secretion GO:0046879 115 0.013
regulation of immune system process GO:0002682 123 0.013
secretion by cell GO:0032940 248 0.013
rna metabolic process GO:0016070 406 0.013
response to vitamin GO:0033273 131 0.013
positive regulation of ion transport GO:0043270 94 0.013
single organism cell adhesion GO:0098602 46 0.013
Mouse
purine ribonucleotide biosynthetic process GO:0009152 81 0.013
transcription dna templated GO:0006351 377 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
regulation of locomotion GO:0040012 148 0.012
neuron projection morphogenesis GO:0048812 122 0.012
negative regulation of signal transduction GO:0009968 83 0.012
nucleic acid templated transcription GO:0097659 379 0.012
response to acid chemical GO:0001101 222 0.012
purine containing compound catabolic process GO:0072523 138 0.012
response to biotic stimulus GO:0009607 226 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
response to external biotic stimulus GO:0043207 221 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
negative regulation of gene expression GO:0010629 199 0.012
regulation of neuron differentiation GO:0045664 208 0.012
female pregnancy GO:0007565 122 0.012
gamete generation GO:0007276 124 0.012
cellular response to external stimulus GO:0071496 118 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
Mouse
dephosphorylation GO:0016311 98 0.012
positive regulation of nervous system development GO:0051962 178 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
rho protein signal transduction GO:0007266 11 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
response to estrogen GO:0043627 232 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
regulation of vasculature development GO:1901342 44 0.012
transmembrane transport GO:0055085 412 0.012
regulation of cell adhesion GO:0030155 52 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.012
ameboidal type cell migration GO:0001667 26 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
action potential GO:0001508 54 0.012
cellular macromolecule localization GO:0070727 122 0.012
amide transport GO:0042886 105 0.012
protein targeting GO:0006605 61 0.012
positive regulation of cell projection organization GO:0031346 111 0.011
organophosphate catabolic process GO:0046434 148 0.011
calcium ion transport GO:0006816 131 0.011
regulation of catabolic process GO:0009894 113 0.011
muscle structure development GO:0061061 87 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
regulation of lipid metabolic process GO:0019216 68 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
negative regulation of protein maturation GO:1903318 47 0.011
cyclic nucleotide biosynthetic process GO:0009190 63 0.011
cell activation GO:0001775 97 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
response to calcium ion GO:0051592 59 0.011
vasculature development GO:0001944 70 0.011
positive regulation of locomotion GO:0040017 102 0.011
blood vessel morphogenesis GO:0048514 58 0.011
anterior posterior pattern specification GO:0009952 1 0.011
positive regulation of behavior GO:0048520 38 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
regulation of transcription dna templated GO:0006355 374 0.011
regulation of neuron projection development GO:0010975 161 0.011
cellular component morphogenesis GO:0032989 155 0.011
lung development GO:0030324 43 0.011
reproductive system development GO:0061458 128 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
regulation of peptide transport GO:0090087 87 0.011
positive regulation of catabolic process GO:0009896 78 0.011
peptide hormone secretion GO:0030072 84 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
cell cycle GO:0007049 101 0.011
regulation of nucleic acid templated transcription GO:1903506 380 0.011
oxidation reduction process GO:0055114 304 0.010
cyclic nucleotide metabolic process GO:0009187 80 0.010
developmental process involved in reproduction GO:0003006 159 0.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.010
nucleotide catabolic process GO:0009166 139 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
hormone transport GO:0009914 121 0.010
cytoskeleton organization GO:0007010 111 0.010
regulation of peptidase activity GO:0052547 55 0.010
cytoplasmic transport GO:0016482 115 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
reproductive structure development GO:0048608 128 0.010
urogenital system development GO:0001655 78 0.010
regulation of map kinase activity GO:0043405 53 0.010
tube development GO:0035295 89 0.010
response to ethanol GO:0045471 162 0.010
blood vessel development GO:0001568 69 0.010
negative regulation of innate immune response GO:0045824 4 0.010
response to amino acid GO:0043200 75 0.010
cellular response to abiotic stimulus GO:0071214 85 0.010
regulation of inflammatory response GO:0050727 48 0.010
forebrain development GO:0030900 98 0.010
response to other organism GO:0051707 220 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010

Lims2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
musculoskeletal system disease DOID:17 0 0.034
nervous system disease DOID:863 0 0.033
myopathy DOID:423 0 0.018
muscular disease DOID:0080000 0 0.018
muscular dystrophy DOID:9884 0 0.018
muscle tissue disease DOID:66 0 0.018
disease of metabolism DOID:0014667 0 0.015
central nervous system disease DOID:331 0 0.015
bone disease DOID:0080001 0 0.014
connective tissue disease DOID:65 0 0.014
cardiovascular system disease DOID:1287 0 0.012