Rattus norvegicus

0 known processes

Plxna2

plexin A2

Plxna2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cell cell signaling GO:0007267 335 0.080
intracellular signal transduction GO:0035556 314 0.063
positive regulation of multicellular organismal process GO:0051240 387 0.058
regulation of phosphorus metabolic process GO:0051174 349 0.057
regulation of programmed cell death GO:0043067 341 0.055
positive regulation of phosphorus metabolic process GO:0010562 262 0.052
regulation of protein metabolic process GO:0051246 289 0.050
regulation of phosphate metabolic process GO:0019220 349 0.049
apoptotic process GO:0006915 381 0.048
positive regulation of cell communication GO:0010647 271 0.047
regulation of signal transduction GO:0009966 318 0.046
positive regulation of signaling GO:0023056 270 0.045
regulation of cell differentiation GO:0045595 320 0.045
cell projection organization GO:0030030 302 0.045
Rat
regulation of phosphorylation GO:0042325 248 0.044
protein phosphorylation GO:0006468 345 0.044
cellular component assembly GO:0022607 360 0.043
Rat
single organism reproductive process GO:0044702 297 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
programmed cell death GO:0012501 392 0.043
organic acid metabolic process GO:0006082 292 0.043
central nervous system development GO:0007417 311 0.042
catabolic process GO:0009056 351 0.041
regulation of cellular protein metabolic process GO:0032268 267 0.041
cellular component biogenesis GO:0044085 368 0.040
Rat
regulation of nervous system development GO:0051960 264 0.039
regulation of apoptotic process GO:0042981 335 0.039
positive regulation of cellular protein metabolic process GO:0032270 167 0.039
lipid metabolic process GO:0006629 283 0.038
signal release GO:0023061 145 0.038
regulation of cellular component organization GO:0051128 368 0.038
Rat
ion transmembrane transport GO:0034220 365 0.037
organophosphate metabolic process GO:0019637 370 0.036
neuron differentiation GO:0030182 368 0.036
rna metabolic process GO:0016070 406 0.036
hormone transport GO:0009914 121 0.036
cell migration GO:0016477 197 0.035
Rat
macromolecular complex assembly GO:0065003 273 0.035
response to nutrient levels GO:0031667 370 0.035
carboxylic acid metabolic process GO:0019752 289 0.035
reproductive process GO:0022414 372 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.034
regulation of intracellular signal transduction GO:1902531 218 0.033
rna biosynthetic process GO:0032774 380 0.033
regulation of neurogenesis GO:0050767 247 0.033
regulation of cell proliferation GO:0042127 359 0.032
positive regulation of cell differentiation GO:0045597 217 0.032
response to extracellular stimulus GO:0009991 380 0.032
regulation of hormone levels GO:0010817 187 0.032
regulation of multicellular organismal development GO:2000026 376 0.032
positive regulation of phosphate metabolic process GO:0045937 262 0.032
negative regulation of metabolic process GO:0009892 331 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.031
cellular response to stress GO:0033554 269 0.031
regulation of molecular function GO:0065009 398 0.031
positive regulation of transport GO:0051050 245 0.030
nucleic acid templated transcription GO:0097659 379 0.030
cellular response to oxygen containing compound GO:1901701 386 0.030
positive regulation of developmental process GO:0051094 283 0.029
positive regulation of protein metabolic process GO:0051247 178 0.029
cell motility GO:0048870 202 0.028
Rat
positive regulation of molecular function GO:0044093 230 0.028
negative regulation of cell death GO:0060548 229 0.028
hormone secretion GO:0046879 115 0.028
neuron projection development GO:0031175 273 0.028
organelle organization GO:0006996 266 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.028
cellular amine metabolic process GO:0044106 38 0.028
regulation of cell development GO:0060284 263 0.028
macromolecular complex subunit organization GO:0043933 339 0.027
oxoacid metabolic process GO:0043436 290 0.027
positive regulation of cell death GO:0010942 184 0.027
response to external biotic stimulus GO:0043207 221 0.027
regulation of rna metabolic process GO:0051252 391 0.027
cellular catabolic process GO:0044248 295 0.027
regulation of protein modification process GO:0031399 194 0.026
protein localization GO:0008104 191 0.026
regulation of secretion GO:0051046 224 0.026
cellular ketone metabolic process GO:0042180 51 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
regulation of cell projection organization GO:0031344 175 0.026
Rat
protein complex biogenesis GO:0070271 263 0.026
protein complex assembly GO:0006461 263 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
negative regulation of signaling GO:0023057 157 0.026
regulation of locomotion GO:0040012 148 0.026
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
response to corticosteroid GO:0031960 235 0.025
anatomical structure morphogenesis GO:0009653 298 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
regulation of dendrite development GO:0050773 59 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
multicellular organism reproduction GO:0032504 233 0.024
regulation of proteasomal protein catabolic process GO:0061136 4 0.024
regulation of cell migration GO:0030334 128 0.024
Rat
regulation of neuron differentiation GO:0045664 208 0.024
secretion GO:0046903 307 0.024
regulation of neuron projection development GO:0010975 161 0.024
regulation of protein phosphorylation GO:0001932 183 0.024
regulation of catalytic activity GO:0050790 304 0.024
neurological system process GO:0050877 219 0.023
negative regulation of response to stimulus GO:0048585 155 0.023
brain development GO:0007420 247 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
nitrogen compound transport GO:0071705 229 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
macromolecule localization GO:0033036 252 0.023
multi organism reproductive process GO:0044703 262 0.023
growth GO:0040007 165 0.022
secretion by cell GO:0032940 248 0.022
negative regulation of apoptotic process GO:0043066 181 0.022
positive regulation of nervous system development GO:0051962 178 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
positive regulation of response to stimulus GO:0048584 285 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
single organism biosynthetic process GO:0044711 342 0.022
neuron development GO:0048666 286 0.022
cellular protein localization GO:0034613 122 0.022
response to oxygen levels GO:0070482 265 0.022
organic substance catabolic process GO:1901575 316 0.022
negative regulation of programmed cell death GO:0043069 183 0.021
cation transport GO:0006812 382 0.021
cell part morphogenesis GO:0032990 123 0.021
tissue development GO:0009888 252 0.021
regulation of rna biosynthetic process GO:2001141 381 0.021
response to carbohydrate GO:0009743 183 0.021
cellular lipid metabolic process GO:0044255 208 0.021
negative regulation of cell communication GO:0010648 158 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
synaptic growth at neuromuscular junction GO:0051124 1 0.021
behavior GO:0007610 205 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
single organism cellular localization GO:1902580 102 0.021
amine metabolic process GO:0009308 38 0.020
regulation of mapk cascade GO:0043408 116 0.020
transcription dna templated GO:0006351 377 0.020
single organism organelle organization GO:1902589 180 0.020
response to growth factor GO:0070848 189 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
neuron apoptotic process GO:0051402 88 0.020
negative regulation of gene expression GO:0010629 199 0.020
cellular homeostasis GO:0019725 252 0.019
regulation of transcription dna templated GO:0006355 374 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
response to ethanol GO:0045471 162 0.019
single organism behavior GO:0044708 130 0.019
response to peptide GO:1901652 292 0.019
regulation of protein kinase activity GO:0045859 105 0.019
positive regulation of cell development GO:0010720 176 0.019
developmental growth GO:0048589 100 0.019
response to decreased oxygen levels GO:0036293 237 0.019
regulation of neuron death GO:1901214 115 0.019
amide transport GO:0042886 105 0.019
cellular macromolecule localization GO:0070727 122 0.019
regulation of cellular localization GO:0060341 263 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
reproduction GO:0000003 245 0.018
cell type specific apoptotic process GO:0097285 134 0.018
localization of cell GO:0051674 202 0.018
Rat
homeostatic process GO:0042592 331 0.018
regulation of cellular component movement GO:0051270 150 0.018
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
purine containing compound metabolic process GO:0072521 253 0.018
locomotion GO:0040011 237 0.018
Rat
response to inorganic substance GO:0010035 377 0.018
regulation of cellular component biogenesis GO:0044087 86 0.018
Rat
regulation of secretion by cell GO:1903530 208 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
chemical homeostasis GO:0048878 292 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
neuromuscular process GO:0050905 2 0.018
multicellular organism growth GO:0035264 1 0.018
response to peptide hormone GO:0043434 278 0.018
protein oligomerization GO:0051259 191 0.018
cellular response to external stimulus GO:0071496 118 0.018
heterocycle catabolic process GO:0046700 167 0.018
positive regulation of protein modification process GO:0031401 142 0.018
ras protein signal transduction GO:0007265 29 0.017
cell cycle GO:0007049 101 0.017
heart morphogenesis GO:0003007 3 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
positive regulation of gene expression GO:0010628 244 0.017
head development GO:0060322 247 0.017
regulation of transferase activity GO:0051338 123 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
response to glucocorticoid GO:0051384 223 0.017
cellular component movement GO:0006928 248 0.017
Rat
cell morphogenesis GO:0000902 142 0.017
response to hexose GO:0009746 144 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
aging GO:0007568 241 0.017
synaptic transmission GO:0007268 235 0.017
intracellular transport GO:0046907 185 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
response to ketone GO:1901654 182 0.017
small molecule biosynthetic process GO:0044283 124 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
response to oxidative stress GO:0006979 186 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
single organism catabolic process GO:0044712 283 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
response to cytokine GO:0034097 215 0.016
regulation of peptide transport GO:0090087 87 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
protein complex subunit organization GO:0071822 302 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
regulation of peptide hormone secretion GO:0090276 80 0.016
cellular component morphogenesis GO:0032989 155 0.016
developmental process involved in reproduction GO:0003006 159 0.016
nucleotide metabolic process GO:0009117 279 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
cation homeostasis GO:0055080 195 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
dendrite development GO:0016358 72 0.016
neuron death GO:0070997 127 0.016
regulation of cell cycle GO:0051726 73 0.016
lipid biosynthetic process GO:0008610 128 0.016
positive regulation of mapk cascade GO:0043410 92 0.016
peptide transport GO:0015833 97 0.016
forebrain development GO:0030900 98 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
response to hypoxia GO:0001666 231 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
anterior posterior pattern specification GO:0009952 1 0.015
positive regulation of secretion GO:0051047 140 0.015
peptide hormone secretion GO:0030072 84 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
response to acid chemical GO:0001101 222 0.015
response to toxic substance GO:0009636 133 0.015
gliogenesis GO:0042063 93 0.015
protein transport GO:0015031 132 0.015
transmembrane transport GO:0055085 412 0.015
positive regulation of synaptic transmission GO:0050806 62 0.015
regulation of synaptic transmission GO:0050804 141 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
peptide secretion GO:0002790 86 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
organic acid catabolic process GO:0016054 49 0.014
cytoplasmic transport GO:0016482 115 0.014
response to estrogen GO:0043627 232 0.014
action potential GO:0001508 54 0.014
cytoskeleton organization GO:0007010 111 0.014
response to metal ion GO:0010038 253 0.014
response to glucose GO:0009749 136 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
regulation of peptide secretion GO:0002791 82 0.014
sexual reproduction GO:0019953 148 0.014
response to monosaccharide GO:0034284 159 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
ion homeostasis GO:0050801 212 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
regulation of kinase activity GO:0043549 117 0.014
adult locomotory behavior GO:0008344 4 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
regulation of hydrolase activity GO:0051336 143 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
regulation of hormone secretion GO:0046883 106 0.013
positive regulation of kinase activity GO:0033674 77 0.013
response to radiation GO:0009314 137 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
negative regulation of transport GO:0051051 136 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
actin cytoskeleton organization GO:0030036 73 0.013
motor neuron axon guidance GO:0008045 1 0.013
defense response GO:0006952 194 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
positive regulation of signal transduction GO:0009967 175 0.013
proteolysis GO:0006508 175 0.013
epithelium development GO:0060429 96 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
regulation of ion transport GO:0043269 245 0.013
regulation of system process GO:0044057 208 0.013
s shaped body morphogenesis GO:0072050 2 0.013
actin filament based process GO:0030029 86 0.013
cellular chemical homeostasis GO:0055082 247 0.013
positive regulation of hormone secretion GO:0046887 65 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
organonitrogen compound catabolic process GO:1901565 179 0.012
aromatic compound catabolic process GO:0019439 168 0.012
mapk cascade GO:0000165 140 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
nucleotide catabolic process GO:0009166 139 0.012
cerebral cortex cell migration GO:0021795 4 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
cofactor metabolic process GO:0051186 95 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
blood circulation GO:0008015 183 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
response to insulin GO:0032868 133 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
metal ion transport GO:0030001 289 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
gastrulation GO:0007369 2 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
circulatory system process GO:0003013 183 0.012
response to purine containing compound GO:0014074 126 0.012
regulation of catabolic process GO:0009894 113 0.012
regulation of cell motility GO:2000145 131 0.012
Rat
negative regulation of developmental process GO:0051093 125 0.012
oxidation reduction process GO:0055114 304 0.012
insulin like growth factor receptor signaling pathway GO:0048009 3 0.012
single organism intracellular transport GO:1902582 166 0.012
circulatory system development GO:0072359 134 0.012
fatty acid metabolic process GO:0006631 99 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.011
cardiac conduction GO:0061337 2 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
response to wounding GO:0009611 254 0.011
organic anion transport GO:0015711 132 0.011
purine containing compound catabolic process GO:0072523 138 0.011
cardiovascular system development GO:0072358 134 0.011
mesoderm development GO:0007498 2 0.011
response to biotic stimulus GO:0009607 226 0.011
salivary gland morphogenesis GO:0007435 1 0.011
protein targeting GO:0006605 61 0.011
divalent inorganic cation transport GO:0072511 134 0.011
gamete generation GO:0007276 124 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
axis specification GO:0009798 4 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
cation transmembrane transport GO:0098655 263 0.011
response to alkaloid GO:0043279 132 0.011
chromosome segregation GO:0007059 2 0.011
cell growth GO:0016049 104 0.011
organophosphate catabolic process GO:0046434 148 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
response to ionizing radiation GO:0010212 59 0.011
intracellular protein transport GO:0006886 79 0.011
protein homooligomerization GO:0051260 91 0.010
monovalent inorganic cation transport GO:0015672 172 0.010
telencephalon development GO:0021537 62 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
carboxylic acid catabolic process GO:0046395 49 0.010
reproductive system development GO:0061458 128 0.010
learning or memory GO:0007611 90 0.010
metal ion homeostasis GO:0055065 186 0.010
multi multicellular organism process GO:0044706 138 0.010
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.010
centrosome organization GO:0051297 1 0.010
cerebral cortex development GO:0021987 18 0.010
negative regulation of molecular function GO:0044092 133 0.010

Plxna2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.051
nervous system disease DOID:863 0 0.051
central nervous system disease DOID:331 0 0.021
disease of metabolism DOID:0014667 0 0.019
inherited metabolic disorder DOID:655 0 0.012
brain disease DOID:936 0 0.011
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010