Rattus norvegicus

0 known processes

Prex2

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2

(Aliases: Depdc2)

Prex2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.135
intracellular signal transduction GO:0035556 314 0.119
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.098
organic acid metabolic process GO:0006082 292 0.097
response to acid chemical GO:0001101 222 0.096
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.094
single organism biosynthetic process GO:0044711 342 0.092
carboxylic acid metabolic process GO:0019752 289 0.090
positive regulation of cell communication GO:0010647 271 0.089
positive regulation of phosphate metabolic process GO:0045937 262 0.086
cation transport GO:0006812 382 0.080
growth GO:0040007 165 0.077
regulation of phosphate metabolic process GO:0019220 349 0.074
protein phosphorylation GO:0006468 345 0.071
cellular response to hormone stimulus GO:0032870 247 0.070
positive regulation of cellular biosynthetic process GO:0031328 295 0.067
regulation of cellular localization GO:0060341 263 0.065
regulation of cellular ketone metabolic process GO:0010565 27 0.064
organophosphate metabolic process GO:0019637 370 0.063
cellular response to endogenous stimulus GO:0071495 377 0.063
positive regulation of transport GO:0051050 245 0.062
positive regulation of biosynthetic process GO:0009891 319 0.062
purine ribonucleotide metabolic process GO:0009150 227 0.061
positive regulation of molecular function GO:0044093 230 0.061
cellular ketone metabolic process GO:0042180 51 0.061
signal transduction by phosphorylation GO:0023014 144 0.061
cellular response to organic cyclic compound GO:0071407 202 0.060
cellular response to stress GO:0033554 269 0.059
negative regulation of metabolic process GO:0009892 331 0.059
tissue development GO:0009888 252 0.058
regulation of phosphorus metabolic process GO:0051174 349 0.058
regulation of molecular function GO:0065009 398 0.057
carbohydrate derivative metabolic process GO:1901135 346 0.056
transcription dna templated GO:0006351 377 0.055
response to biotic stimulus GO:0009607 226 0.055
small molecule biosynthetic process GO:0044283 124 0.054
rna metabolic process GO:0016070 406 0.054
brain development GO:0007420 247 0.053
regulation of apoptotic process GO:0042981 335 0.053
regulation of protein metabolic process GO:0051246 289 0.052
reproductive process GO:0022414 372 0.052
homeostatic process GO:0042592 331 0.052
cellular amino acid metabolic process GO:0006520 107 0.051
response to inorganic substance GO:0010035 377 0.051
amine metabolic process GO:0009308 38 0.050
regulation of protein modification process GO:0031399 194 0.050
regulation of hormone levels GO:0010817 187 0.050
regulation of cell proliferation GO:0042127 359 0.050
macromolecule localization GO:0033036 252 0.049
cellular component assembly GO:0022607 360 0.049
Rat
ion transmembrane transport GO:0034220 365 0.049
response to peptide hormone GO:0043434 278 0.049
regulation of transcription dna templated GO:0006355 374 0.048
ion homeostasis GO:0050801 212 0.048
regulation of rna biosynthetic process GO:2001141 381 0.048
smooth muscle cell proliferation GO:0048659 77 0.048
positive regulation of signaling GO:0023056 270 0.048
nucleobase containing small molecule metabolic process GO:0055086 316 0.047
response to peptide GO:1901652 292 0.047
regulation of nucleic acid templated transcription GO:1903506 380 0.047
response to other organism GO:0051707 220 0.046
inflammatory response GO:0006954 150 0.045
regulation of signal transduction GO:0009966 318 0.044
cellular amine metabolic process GO:0044106 38 0.044
cell migration GO:0016477 197 0.043
macromolecular complex subunit organization GO:0043933 339 0.042
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.042
regulation of cellular amine metabolic process GO:0033238 8 0.042
secretion by cell GO:0032940 248 0.042
multicellular organismal reproductive process GO:0048609 233 0.042
response to oxidative stress GO:0006979 186 0.041
positive regulation of cell proliferation GO:0008284 249 0.041
nucleoside phosphate metabolic process GO:0006753 283 0.041
cellular response to lipid GO:0071396 201 0.041
multicellular organism reproduction GO:0032504 233 0.041
secretion GO:0046903 307 0.041
apoptotic process GO:0006915 381 0.041
organonitrogen compound biosynthetic process GO:1901566 167 0.040
cellular divalent inorganic cation homeostasis GO:0072503 162 0.040
transcription from rna polymerase ii promoter GO:0006366 252 0.040
regulation of catalytic activity GO:0050790 304 0.040
central nervous system development GO:0007417 311 0.040
metal ion transport GO:0030001 289 0.040
programmed cell death GO:0012501 392 0.039
response to extracellular stimulus GO:0009991 380 0.039
rna biosynthetic process GO:0032774 380 0.039
aging GO:0007568 241 0.039
response to glucocorticoid GO:0051384 223 0.038
muscle cell proliferation GO:0033002 84 0.038
cytosolic calcium ion homeostasis GO:0051480 140 0.038
organic substance catabolic process GO:1901575 316 0.038
cellular lipid metabolic process GO:0044255 208 0.038
purine containing compound metabolic process GO:0072521 253 0.037
cell cell signaling GO:0007267 335 0.037
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
nitrogen compound transport GO:0071705 229 0.037
regulation of system process GO:0044057 208 0.037
catabolic process GO:0009056 351 0.037
regulation of locomotion GO:0040012 148 0.037
metal ion homeostasis GO:0055065 186 0.036
regulation of programmed cell death GO:0043067 341 0.036
response to wounding GO:0009611 254 0.036
positive regulation of phosphorus metabolic process GO:0010562 262 0.036
chemical homeostasis GO:0048878 292 0.036
response to ethanol GO:0045471 162 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.036
regulation of cellular protein metabolic process GO:0032268 267 0.035
regulation of rna metabolic process GO:0051252 391 0.035
positive regulation of transcription dna templated GO:0045893 197 0.035
neuron death GO:0070997 127 0.035
locomotion GO:0040011 237 0.035
positive regulation of signal transduction GO:0009967 175 0.035
positive regulation of cellular component organization GO:0051130 200 0.034
transmembrane transport GO:0055085 412 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.034
response to ketone GO:1901654 182 0.033
cellular response to oxygen containing compound GO:1901701 386 0.033
purine nucleotide metabolic process GO:0006163 229 0.033
hormone transport GO:0009914 121 0.033
protein localization GO:0008104 191 0.033
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.033
cyclic nucleotide metabolic process GO:0009187 80 0.033
regulation of phosphorylation GO:0042325 248 0.033
positive regulation of nucleic acid templated transcription GO:1903508 197 0.032
lipid metabolic process GO:0006629 283 0.032
regulation of hormone secretion GO:0046883 106 0.032
positive regulation of protein metabolic process GO:0051247 178 0.032
response to corticosteroid GO:0031960 235 0.032
response to oxygen levels GO:0070482 265 0.031
single organism catabolic process GO:0044712 283 0.031
response to decreased oxygen levels GO:0036293 237 0.031
positive regulation of rna metabolic process GO:0051254 203 0.031
ribose phosphate biosynthetic process GO:0046390 87 0.031
nucleotide metabolic process GO:0009117 279 0.031
neurological system process GO:0050877 219 0.030
blood circulation GO:0008015 183 0.030
positive regulation of gene expression GO:0010628 244 0.030
nucleic acid templated transcription GO:0097659 379 0.030
positive regulation of response to stimulus GO:0048584 285 0.030
single organism reproductive process GO:0044702 297 0.030
anatomical structure morphogenesis GO:0009653 298 0.030
ribonucleotide metabolic process GO:0009259 231 0.029
cellular response to nitrogen compound GO:1901699 210 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
regulation of neuron death GO:1901214 115 0.028
purine ribonucleotide biosynthetic process GO:0009152 81 0.028
positive regulation of intracellular signal transduction GO:1902533 138 0.028
oxidation reduction process GO:0055114 304 0.028
calcium ion transport GO:0006816 131 0.028
negative regulation of cell death GO:0060548 229 0.028
organelle organization GO:0006996 266 0.028
Rat
small gtpase mediated signal transduction GO:0007264 36 0.028
positive regulation of cellular amine metabolic process GO:0033240 3 0.028
regulation of secretion by cell GO:1903530 208 0.028
cellular response to peptide GO:1901653 133 0.028
positive regulation of catalytic activity GO:0043085 184 0.028
cellular ion homeostasis GO:0006873 184 0.028
negative regulation of cellular biosynthetic process GO:0031327 161 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.028
cytoskeleton organization GO:0007010 111 0.028
Rat
organophosphate biosynthetic process GO:0090407 143 0.027
cellular chemical homeostasis GO:0055082 247 0.027
defense response GO:0006952 194 0.027
behavior GO:0007610 205 0.027
cation homeostasis GO:0055080 195 0.027
ras protein signal transduction GO:0007265 29 0.027
regulation of secretion GO:0051046 224 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
synaptic growth at neuromuscular junction GO:0051124 1 0.026
positive regulation of developmental process GO:0051094 283 0.026
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.026
hormone secretion GO:0046879 115 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
cell motility GO:0048870 202 0.026
lipid biosynthetic process GO:0008610 128 0.026
regulation of response to external stimulus GO:0032101 106 0.025
peptidyl amino acid modification GO:0018193 126 0.025
regulation of cell differentiation GO:0045595 320 0.025
Rat
establishment of protein localization GO:0045184 141 0.025
purine nucleotide biosynthetic process GO:0006164 83 0.025
regulation of blood circulation GO:1903522 110 0.025
action potential GO:0001508 54 0.024
response to carbohydrate GO:0009743 183 0.024
cellular component movement GO:0006928 248 0.024
regulation of anatomical structure morphogenesis GO:0022603 141 0.024
proteolysis GO:0006508 175 0.024
cellular calcium ion homeostasis GO:0006874 160 0.024
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
negative regulation of apoptotic process GO:0043066 181 0.024
regulation of peptide transport GO:0090087 87 0.024
heart process GO:0003015 57 0.024
negative regulation of gene expression GO:0010629 199 0.024
gland development GO:0048732 155 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
regulation of nucleotide metabolic process GO:0006140 117 0.024
rhythmic process GO:0048511 156 0.024
purine containing compound biosynthetic process GO:0072522 85 0.024
immune system process GO:0002376 204 0.024
cell projection organization GO:0030030 302 0.023
Rat
cellular catabolic process GO:0044248 295 0.023
single organism organelle organization GO:1902589 180 0.023
Rat
regulation of neuron apoptotic process GO:0043523 83 0.023
positive regulation of nervous system development GO:0051962 178 0.023
membrane organization GO:0061024 94 0.023
actin cytoskeleton organization GO:0030036 73 0.023
Rat
regulation of hydrolase activity GO:0051336 143 0.023
cellular homeostasis GO:0019725 252 0.023
response to nutrient levels GO:0031667 370 0.023
regulation of smooth muscle cell proliferation GO:0048660 75 0.023
regulation of cellular component organization GO:0051128 368 0.023
Rat
actin filament based process GO:0030029 86 0.022
Rat
cellular metal ion homeostasis GO:0006875 172 0.022
nucleoside phosphate catabolic process GO:1901292 140 0.022
response to growth factor GO:0070848 189 0.022
cellular component biogenesis GO:0044085 368 0.022
Rat
purine nucleoside triphosphate metabolic process GO:0009144 141 0.022
regulation of membrane potential GO:0042391 110 0.022
regulation of purine nucleotide metabolic process GO:1900542 115 0.022
response to bacterium GO:0009617 200 0.022
telencephalon development GO:0021537 62 0.022
carbohydrate derivative biosynthetic process GO:1901137 124 0.022
reproduction GO:0000003 245 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
response to hypoxia GO:0001666 231 0.022
regulation of response to stress GO:0080134 126 0.022
localization of cell GO:0051674 202 0.021
positive regulation of protein phosphorylation GO:0001934 135 0.021
biological adhesion GO:0022610 110 0.021
response to radiation GO:0009314 137 0.021
positive regulation of cell development GO:0010720 176 0.021
inorganic ion transmembrane transport GO:0098660 229 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
response to molecule of bacterial origin GO:0002237 194 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
negative regulation of signaling GO:0023057 157 0.021
positive regulation of protein modification process GO:0031401 142 0.021
neuron projection development GO:0031175 273 0.021
Rat
neuron apoptotic process GO:0051402 88 0.021
regulation of growth GO:0040008 105 0.021
cellular protein localization GO:0034613 122 0.021
regulation of mapk cascade GO:0043408 116 0.020
calcium ion homeostasis GO:0055074 162 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.020
monocarboxylic acid metabolic process GO:0032787 152 0.020
cellular macromolecule localization GO:0070727 122 0.020
vesicle mediated transport GO:0016192 181 0.020
head development GO:0060322 247 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
divalent inorganic cation transport GO:0072511 134 0.020
positive regulation of locomotion GO:0040017 102 0.020
regulation of peptide hormone secretion GO:0090276 80 0.020
protein complex biogenesis GO:0070271 263 0.020
Rat
sexual reproduction GO:0019953 148 0.020
muscle system process GO:0003012 115 0.020
regulation of anatomical structure size GO:0090066 135 0.020
Rat
negative regulation of cell communication GO:0010648 158 0.020
regulation of muscle system process GO:0090257 79 0.020
positive regulation of secretion by cell GO:1903532 128 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.020
response to external biotic stimulus GO:0043207 221 0.020
response to estrogen GO:0043627 232 0.019
response to estradiol GO:0032355 164 0.019
multi organism reproductive process GO:0044703 262 0.019
positive regulation of cell death GO:0010942 184 0.019
ribonucleotide biosynthetic process GO:0009260 85 0.019
cyclic nucleotide biosynthetic process GO:0009190 63 0.019
cellular cation homeostasis GO:0030003 180 0.019
regulation of metal ion transport GO:0010959 118 0.019
nucleotide biosynthetic process GO:0009165 98 0.019
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.019
nucleoside phosphate biosynthetic process GO:1901293 102 0.019
regulation of cell growth GO:0001558 85 0.019
signal release GO:0023061 145 0.019
carbohydrate derivative catabolic process GO:1901136 147 0.019
response to toxic substance GO:0009636 133 0.019
positive regulation of mapk cascade GO:0043410 92 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
monovalent inorganic cation transport GO:0015672 172 0.018
heart contraction GO:0060047 57 0.018
protein transport GO:0015031 132 0.018
organic hydroxy compound transport GO:0015850 77 0.018
mapk cascade GO:0000165 140 0.018
cell adhesion GO:0007155 110 0.018
cellular response to glucocorticoid stimulus GO:0071385 68 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
nucleoside triphosphate metabolic process GO:0009141 144 0.018
negative regulation of programmed cell death GO:0043069 183 0.018
negative regulation of molecular function GO:0044092 133 0.018
multicellular organism growth GO:0035264 1 0.018
regulation of nervous system development GO:0051960 264 0.018
Rat
carbohydrate metabolic process GO:0005975 130 0.018
purine containing compound catabolic process GO:0072523 138 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.017
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
developmental growth GO:0048589 100 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
organic anion transport GO:0015711 132 0.017
single organism intracellular transport GO:1902582 166 0.017
gamete generation GO:0007276 124 0.017
cellular response to steroid hormone stimulus GO:0071383 93 0.017
cell activation GO:0001775 97 0.017
single organism membrane organization GO:0044802 74 0.017
regulation of synaptic transmission GO:0050804 141 0.017
response to cytokine GO:0034097 215 0.017
regulation of ion transport GO:0043269 245 0.017
protein complex assembly GO:0006461 263 0.016
Rat
ribonucleotide catabolic process GO:0009261 136 0.016
cellular response to corticosteroid stimulus GO:0071384 69 0.016
b cell differentiation GO:0030183 2 0.016
synaptic transmission GO:0007268 235 0.016
positive regulation of kinase activity GO:0033674 77 0.016
peptide hormone secretion GO:0030072 84 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
axonogenesis GO:0007409 71 0.016
cell growth GO:0016049 104 0.016
limbic system development GO:0021761 38 0.016
alcohol metabolic process GO:0006066 77 0.016
regulation of kinase activity GO:0043549 117 0.016
negative regulation of secretion GO:0051048 82 0.016
negative regulation of transport GO:0051051 136 0.016
organophosphate catabolic process GO:0046434 148 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
response to corticosterone GO:0051412 40 0.016
regulation of ion homeostasis GO:2000021 63 0.016
stress activated protein kinase signaling cascade GO:0031098 37 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
forebrain development GO:0030900 98 0.016
salivary gland morphogenesis GO:0007435 1 0.016
cellular component morphogenesis GO:0032989 155 0.015
regeneration GO:0031099 163 0.015
cognition GO:0050890 92 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.015
hormone metabolic process GO:0042445 69 0.015
divalent metal ion transport GO:0070838 132 0.015
axis specification GO:0009798 4 0.015
regulation of homeostatic process GO:0032844 101 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.015
regulation of peptide secretion GO:0002791 82 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
response to nutrient GO:0007584 248 0.015
cation transmembrane transport GO:0098655 263 0.015
nucleotide catabolic process GO:0009166 139 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
regulation of transferase activity GO:0051338 123 0.015
cyclic purine nucleotide metabolic process GO:0052652 62 0.015
carbohydrate homeostasis GO:0033500 75 0.015
cytoplasmic transport GO:0016482 115 0.015
response to mineralocorticoid GO:0051385 49 0.014
isoprenoid metabolic process GO:0006720 45 0.014
cellular hormone metabolic process GO:0034754 49 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
tube development GO:0035295 89 0.014
anion transport GO:0006820 178 0.014
nucleoside metabolic process GO:0009116 179 0.014
single organism cellular localization GO:1902580 102 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.014
response to reactive oxygen species GO:0000302 120 0.014
response to insulin GO:0032868 133 0.014
regulation of cell development GO:0060284 263 0.014
Rat
response to mechanical stimulus GO:0009612 134 0.014
sensory perception of pain GO:0019233 73 0.014
regulation of protein kinase activity GO:0045859 105 0.014
aromatic compound catabolic process GO:0019439 168 0.014
liver development GO:0001889 90 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.014
leukocyte activation GO:0045321 76 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
cellular response to hypoxia GO:0071456 51 0.013
fatty acid oxidation GO:0019395 29 0.013
neuron differentiation GO:0030182 368 0.013
Rat
muscle structure development GO:0061061 87 0.013
regulation of response to wounding GO:1903034 69 0.013
multicellular organismal signaling GO:0035637 44 0.013
insulin secretion GO:0030073 69 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
intracellular transport GO:0046907 185 0.013
small molecule catabolic process GO:0044282 59 0.013
positive regulation of transferase activity GO:0051347 81 0.013
regulation of lipid metabolic process GO:0019216 68 0.013
sequestering of calcium ion GO:0051208 8 0.013
female pregnancy GO:0007565 122 0.013
protein complex subunit organization GO:0071822 302 0.013
Rat
negative regulation of developmental process GO:0051093 125 0.013
actin mediated cell contraction GO:0070252 12 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
gonad development GO:0008406 104 0.013
regulation of organelle organization GO:0033043 80 0.013
Rat
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
regulation of homotypic cell cell adhesion GO:0034110 4 0.013
cellular response to alcohol GO:0097306 87 0.012
rho protein signal transduction GO:0007266 11 0.012
maintenance of location GO:0051235 17 0.012
hepaticobiliary system development GO:0061008 90 0.012
negative regulation of neuron death GO:1901215 69 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
salivary gland development GO:0007431 3 0.012
sex differentiation GO:0007548 113 0.012
cardiac muscle cell contraction GO:0086003 10 0.012
dendrite development GO:0016358 72 0.012
Rat
amide transport GO:0042886 105 0.012
regulation of muscle contraction GO:0006937 53 0.012
c21 steroid hormone biosynthetic process GO:0006700 10 0.012
cardiovascular system development GO:0072358 134 0.012
epithelial cell differentiation GO:0030855 71 0.012
heterocycle catabolic process GO:0046700 167 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
chromosome segregation GO:0007059 2 0.012
spermatogenesis GO:0007283 99 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
regulation of dendrite development GO:0050773 59 0.012
Rat
carboxylic acid catabolic process GO:0046395 49 0.012
wound healing GO:0042060 122 0.012
reproductive system development GO:0061458 128 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
single organism behavior GO:0044708 130 0.012
regulation of neurogenesis GO:0050767 247 0.011
Rat
regulation of synaptic plasticity GO:0048167 70 0.011
carboxylic acid biosynthetic process GO:0046394 83 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
female sex differentiation GO:0046660 59 0.011
learning or memory GO:0007611 90 0.011
monosaccharide metabolic process GO:0005996 61 0.011
neuron development GO:0048666 286 0.011
Rat
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.011
regulation of catabolic process GO:0009894 113 0.011
cell cycle GO:0007049 101 0.011
ossification GO:0001503 70 0.011
sensory perception GO:0007600 101 0.011
axon development GO:0061564 96 0.011
camp metabolic process GO:0046058 63 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
erk1 and erk2 cascade GO:0070371 48 0.011
sodium ion transport GO:0006814 82 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
neuron projection morphogenesis GO:0048812 122 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
heart morphogenesis GO:0003007 3 0.011
positive regulation of cyclase activity GO:0031281 15 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
response to alkaloid GO:0043279 132 0.011
actin filament based movement GO:0030048 16 0.011
regulation of developmental growth GO:0048638 45 0.011
regulation of cellular component movement GO:0051270 150 0.011
male gamete generation GO:0048232 99 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
developmental process involved in reproduction GO:0003006 159 0.011
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
cell projection morphogenesis GO:0048858 123 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
regulation of cell migration GO:0030334 128 0.011
regulation of cell projection organization GO:0031344 175 0.011
Rat
regulation of multicellular organismal development GO:2000026 376 0.011
Rat
embryonic pattern specification GO:0009880 1 0.011
sodium ion transmembrane transport GO:0035725 67 0.011
cofactor metabolic process GO:0051186 95 0.011
regulation of body fluid levels GO:0050878 90 0.011
anterior posterior pattern specification GO:0009952 1 0.011
epithelium development GO:0060429 96 0.011
neuron neuron synaptic transmission GO:0007270 60 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
positive regulation of neuron projection development GO:0010976 99 0.010
negative regulation of neuron apoptotic process GO:0043524 45 0.010
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 3 0.010
fatty acid metabolic process GO:0006631 99 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
cellular response to external stimulus GO:0071496 118 0.010
regulation of heart contraction GO:0008016 48 0.010
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
response to hydrogen peroxide GO:0042542 89 0.010
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
regulation of cell motility GO:2000145 131 0.010

Prex2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
central nervous system disease DOID:331 0 0.023
disease of metabolism DOID:0014667 0 0.010
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010