Rattus norvegicus

35 known processes

Wfdc1

WAP four-disulfide core domain 1

(Aliases: ps20)

Wfdc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.095
reproductive process GO:0022414 372 0.095
regulation of signal transduction GO:0009966 318 0.082
rna metabolic process GO:0016070 406 0.077
positive regulation of phosphate metabolic process GO:0045937 262 0.076
macromolecular complex assembly GO:0065003 273 0.075
intracellular signal transduction GO:0035556 314 0.074
positive regulation of signaling GO:0023056 270 0.070
protein complex subunit organization GO:0071822 302 0.067
regulation of phosphate metabolic process GO:0019220 349 0.063
carboxylic acid metabolic process GO:0019752 289 0.062
response to metal ion GO:0010038 253 0.062
single organism biosynthetic process GO:0044711 342 0.061
anatomical structure morphogenesis GO:0009653 298 0.060
protein complex assembly GO:0006461 263 0.057
lipid metabolic process GO:0006629 283 0.057
protein complex biogenesis GO:0070271 263 0.056
regulation of cell proliferation GO:0042127 359 0.056
cellular response to stress GO:0033554 269 0.056
single organism reproductive process GO:0044702 297 0.056
nucleic acid templated transcription GO:0097659 379 0.053
positive regulation of phosphorus metabolic process GO:0010562 262 0.053
protein oligomerization GO:0051259 191 0.052
cellular catabolic process GO:0044248 295 0.052
regulation of phosphorus metabolic process GO:0051174 349 0.051
organic acid metabolic process GO:0006082 292 0.050
single organism catabolic process GO:0044712 283 0.050
response to glucocorticoid GO:0051384 223 0.047
negative regulation of metabolic process GO:0009892 331 0.047
positive regulation of biosynthetic process GO:0009891 319 0.047
regulation of phosphorylation GO:0042325 248 0.044
cellular component assembly GO:0022607 360 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.043
positive regulation of cell communication GO:0010647 271 0.043
macromolecule localization GO:0033036 252 0.043
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.042
multi organism reproductive process GO:0044703 262 0.042
response to acid chemical GO:0001101 222 0.042
catabolic process GO:0009056 351 0.041
response to corticosteroid GO:0031960 235 0.040
organophosphate metabolic process GO:0019637 370 0.040
protein phosphorylation GO:0006468 345 0.039
multicellular organism reproduction GO:0032504 233 0.038
response to decreased oxygen levels GO:0036293 237 0.038
regulation of rna biosynthetic process GO:2001141 381 0.037
regulation of rna metabolic process GO:0051252 391 0.037
regulation of cellular protein metabolic process GO:0032268 267 0.036
response to oxygen levels GO:0070482 265 0.036
reproduction GO:0000003 245 0.036
organelle organization GO:0006996 266 0.036
cellular component biogenesis GO:0044085 368 0.036
cellular amino acid metabolic process GO:0006520 107 0.035
positive regulation of phosphorylation GO:0042327 177 0.035
positive regulation of cellular biosynthetic process GO:0031328 295 0.035
negative regulation of rna metabolic process GO:0051253 123 0.035
multicellular organismal reproductive process GO:0048609 233 0.035
rna biosynthetic process GO:0032774 380 0.035
regulation of transcription dna templated GO:0006355 374 0.033
programmed cell death GO:0012501 392 0.033
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
regulation of molecular function GO:0065009 398 0.032
macromolecular complex subunit organization GO:0043933 339 0.032
response to nutrient levels GO:0031667 370 0.032
regulation of intracellular signal transduction GO:1902531 218 0.032
positive regulation of signal transduction GO:0009967 175 0.032
nucleotide metabolic process GO:0009117 279 0.032
oxoacid metabolic process GO:0043436 290 0.031
regulation of programmed cell death GO:0043067 341 0.031
aging GO:0007568 241 0.031
negative regulation of cellular metabolic process GO:0031324 281 0.031
response to estradiol GO:0032355 164 0.031
central nervous system development GO:0007417 311 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.030
regulation of catalytic activity GO:0050790 304 0.030
cellular component movement GO:0006928 248 0.030
transcription dna templated GO:0006351 377 0.029
anion transport GO:0006820 178 0.029
developmental process involved in reproduction GO:0003006 159 0.029
response to estrogen GO:0043627 232 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
reproductive structure development GO:0048608 128 0.029
cellular amine metabolic process GO:0044106 38 0.029
positive regulation of gene expression GO:0010628 244 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
response to glucose GO:0009749 136 0.029
positive regulation of response to stimulus GO:0048584 285 0.028
secretion GO:0046903 307 0.028
organic substance catabolic process GO:1901575 316 0.028
biological adhesion GO:0022610 110 0.028
response to nutrient GO:0007584 248 0.027
apoptotic process GO:0006915 381 0.027
single organism organelle organization GO:1902589 180 0.027
neuron differentiation GO:0030182 368 0.027
urogenital system development GO:0001655 78 0.027
response to ethanol GO:0045471 162 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
response to peptide GO:1901652 292 0.026
response to peptide hormone GO:0043434 278 0.026
response to extracellular stimulus GO:0009991 380 0.026
response to hypoxia GO:0001666 231 0.026
cell adhesion GO:0007155 110 0.026
head development GO:0060322 247 0.026
regulation of neurogenesis GO:0050767 247 0.025
cell projection organization GO:0030030 302 0.025
regulation of cell differentiation GO:0045595 320 0.025
organonitrogen compound biosynthetic process GO:1901566 167 0.025
lipid biosynthetic process GO:0008610 128 0.024
ribonucleotide metabolic process GO:0009259 231 0.024
amine metabolic process GO:0009308 38 0.024
response to radiation GO:0009314 137 0.024
positive regulation of molecular function GO:0044093 230 0.024
response to other organism GO:0051707 220 0.024
regulation of hormone levels GO:0010817 187 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
rhythmic process GO:0048511 156 0.024
cellular ketone metabolic process GO:0042180 51 0.024
protein homooligomerization GO:0051260 91 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
neuron development GO:0048666 286 0.023
gonad development GO:0008406 104 0.023
localization of cell GO:0051674 202 0.023
response to transition metal nanoparticle GO:1990267 122 0.023
regulation of protein phosphorylation GO:0001932 183 0.023
response to external biotic stimulus GO:0043207 221 0.023
regulation of apoptotic process GO:0042981 335 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
positive regulation of protein metabolic process GO:0051247 178 0.022
cellular lipid metabolic process GO:0044255 208 0.022
organonitrogen compound catabolic process GO:1901565 179 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
response to ketone GO:1901654 182 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
protein localization GO:0008104 191 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
monocarboxylic acid metabolic process GO:0032787 152 0.022
homeostatic process GO:0042592 331 0.022
circulatory system development GO:0072359 134 0.022
response to carbohydrate GO:0009743 183 0.022
negative regulation of response to stimulus GO:0048585 155 0.022
cellular response to organic cyclic compound GO:0071407 202 0.022
response to biotic stimulus GO:0009607 226 0.021
negative regulation of gene expression GO:0010629 199 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
female pregnancy GO:0007565 122 0.021
regeneration GO:0031099 163 0.021
blood circulation GO:0008015 183 0.021
positive regulation of intracellular signal transduction GO:1902533 138 0.021
reproductive system development GO:0061458 128 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
regulation of cell development GO:0060284 263 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
positive regulation of cellular protein metabolic process GO:0032270 167 0.020
chemical homeostasis GO:0048878 292 0.020
cellular response to glucocorticoid stimulus GO:0071385 68 0.020
regulation of neuron projection development GO:0010975 161 0.020
response to wounding GO:0009611 254 0.020
positive regulation of mapk cascade GO:0043410 92 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
growth GO:0040007 165 0.020
brain development GO:0007420 247 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
cellular response to oxygen containing compound GO:1901701 386 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
multi multicellular organism process GO:0044706 138 0.019
regulation of protein metabolic process GO:0051246 289 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
establishment of protein localization GO:0045184 141 0.019
response to monosaccharide GO:0034284 159 0.019
single organism carbohydrate metabolic process GO:0044723 118 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
gland development GO:0048732 155 0.018
mapk cascade GO:0000165 140 0.018
cell cell signaling GO:0007267 335 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.018
regulation of neuron differentiation GO:0045664 208 0.018
neuron projection development GO:0031175 273 0.018
negative regulation of cell proliferation GO:0008285 119 0.018
negative regulation of molecular function GO:0044092 133 0.018
regulation of cellular localization GO:0060341 263 0.018
tube development GO:0035295 89 0.018
regulation of protein modification process GO:0031399 194 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
regulation of secretion by cell GO:1903530 208 0.018
sexual reproduction GO:0019953 148 0.018
development of primary sexual characteristics GO:0045137 107 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
carbohydrate metabolic process GO:0005975 130 0.017
carboxylic acid biosynthetic process GO:0046394 83 0.017
sex differentiation GO:0007548 113 0.017
response to cytokine GO:0034097 215 0.017
cellular response to cytokine stimulus GO:0071345 127 0.017
behavior GO:0007610 205 0.017
transmembrane transport GO:0055085 412 0.017
ion homeostasis GO:0050801 212 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
vesicle mediated transport GO:0016192 181 0.017
regulation of cellular component organization GO:0051128 368 0.017
single organism cellular localization GO:1902580 102 0.017
gamete generation GO:0007276 124 0.017
cellular component morphogenesis GO:0032989 155 0.017
response to insulin GO:0032868 133 0.017
regulation of system process GO:0044057 208 0.017
regulation of transferase activity GO:0051338 123 0.016
immune system process GO:0002376 204 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
ras protein signal transduction GO:0007265 29 0.016
regulation of nervous system development GO:0051960 264 0.016
hormone metabolic process GO:0042445 69 0.016
purine containing compound metabolic process GO:0072521 253 0.016
negative regulation of transcription dna templated GO:0045892 116 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
alcohol metabolic process GO:0006066 77 0.016
positive regulation of protein modification process GO:0031401 142 0.016
cellular response to lipid GO:0071396 201 0.016
tissue development GO:0009888 252 0.016
response to hexose GO:0009746 144 0.016
heart morphogenesis GO:0003007 3 0.016
regulation of mapk cascade GO:0043408 116 0.016
fatty acid metabolic process GO:0006631 99 0.016
positive regulation of developmental process GO:0051094 283 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
retinal metabolic process GO:0042574 3 0.016
response to oxidative stress GO:0006979 186 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.015
hormone secretion GO:0046879 115 0.015
cell type specific apoptotic process GO:0097285 134 0.015
carboxylic acid transport GO:0046942 115 0.015
response to lipopolysaccharide GO:0032496 191 0.015
negative regulation of cell death GO:0060548 229 0.015
organic acid biosynthetic process GO:0016053 83 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
cytoskeleton organization GO:0007010 111 0.015
cellular carbohydrate metabolic process GO:0044262 72 0.015
regulation of growth GO:0040008 105 0.015
regulation of secretion GO:0051046 224 0.015
kidney development GO:0001822 67 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
cellular chemical homeostasis GO:0055082 247 0.015
signal release GO:0023061 145 0.015
positive regulation of transport GO:0051050 245 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
secretion by cell GO:0032940 248 0.015
regulation of hydrolase activity GO:0051336 143 0.015
small molecule biosynthetic process GO:0044283 124 0.015
axis specification GO:0009798 4 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
cellular macromolecule localization GO:0070727 122 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
organ morphogenesis GO:0009887 75 0.014
cell cycle GO:0007049 101 0.014
single organism behavior GO:0044708 130 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
multicellular organism growth GO:0035264 1 0.014
organophosphate catabolic process GO:0046434 148 0.014
renal system development GO:0072001 67 0.014
heterocycle catabolic process GO:0046700 167 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
nitrogen compound transport GO:0071705 229 0.014
response to growth factor GO:0070848 189 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
lung development GO:0030324 43 0.014
circulatory system process GO:0003013 183 0.014
cellular ion homeostasis GO:0006873 184 0.014
single organismal cell cell adhesion GO:0016337 42 0.014
respiratory system development GO:0060541 45 0.014
response to bacterium GO:0009617 200 0.014
regulation of protein kinase activity GO:0045859 105 0.014
negative regulation of cell communication GO:0010648 158 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
blood vessel morphogenesis GO:0048514 58 0.013
cellular amide metabolic process GO:0043603 44 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
ion transmembrane transport GO:0034220 365 0.013
regulation of organelle organization GO:0033043 80 0.013
cellular protein localization GO:0034613 122 0.013
positive regulation of cell death GO:0010942 184 0.013
regulation of immunoglobulin secretion GO:0051023 1 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
response to calcium ion GO:0051592 59 0.013
negative regulation of signaling GO:0023057 157 0.013
cyclic nucleotide metabolic process GO:0009187 80 0.013
sulfur compound metabolic process GO:0006790 70 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
amide transport GO:0042886 105 0.013
cellular homeostasis GO:0019725 252 0.013
metal ion homeostasis GO:0055065 186 0.013
liver development GO:0001889 90 0.013
peptide secretion GO:0002790 86 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
cellular cation homeostasis GO:0030003 180 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
regulation of cell adhesion GO:0030155 52 0.012
cytoskeleton dependent cytokinesis GO:0061640 2 0.012
regulation of hormone secretion GO:0046883 106 0.012
wound healing GO:0042060 122 0.012
circadian rhythm GO:0007623 88 0.012
cytoplasmic transport GO:0016482 115 0.012
ovulation cycle GO:0042698 67 0.012
respiratory tube development GO:0030323 43 0.012
embryonic pattern specification GO:0009880 1 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
neurological system process GO:0050877 219 0.012
actin filament based process GO:0030029 86 0.012
protein transport GO:0015031 132 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
epithelial cell differentiation GO:0030855 71 0.012
anterior posterior pattern specification GO:0009952 1 0.012
cation transport GO:0006812 382 0.012
cation homeostasis GO:0055080 195 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
steroid metabolic process GO:0008202 73 0.012
nucleotide catabolic process GO:0009166 139 0.012
muscle system process GO:0003012 115 0.012
muscle structure development GO:0061061 87 0.012
multicellular organismal signaling GO:0035637 44 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
response to mechanical stimulus GO:0009612 134 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
single organism intracellular transport GO:1902582 166 0.012
membrane organization GO:0061024 94 0.012
response to fatty acid GO:0070542 65 0.011
regulation of response to stress GO:0080134 126 0.011
response to toxic substance GO:0009636 133 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
response to organophosphorus GO:0046683 102 0.011
cell activation GO:0001775 97 0.011
cellular response to alcohol GO:0097306 87 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
cardiovascular system development GO:0072358 134 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
response to reactive oxygen species GO:0000302 120 0.011
response to purine containing compound GO:0014074 126 0.011
single organism cell adhesion GO:0098602 46 0.011
maintenance of location GO:0051235 17 0.011
intracellular transport GO:0046907 185 0.011
cofactor metabolic process GO:0051186 95 0.011
response to hydrogen peroxide GO:0042542 89 0.011
gastrulation GO:0007369 2 0.011
positive regulation of locomotion GO:0040017 102 0.011
hexose metabolic process GO:0019318 58 0.011
lipid localization GO:0010876 62 0.011
response to activity GO:0014823 73 0.011
regulation of kinase activity GO:0043549 117 0.011
response to camp GO:0051591 91 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
proteolysis GO:0006508 175 0.011
protein heterooligomerization GO:0051291 89 0.010
synaptic transmission GO:0007268 235 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
cell morphogenesis GO:0000902 142 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
regulation of peptide secretion GO:0002791 82 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
hormone transport GO:0009914 121 0.010
actin cytoskeleton organization GO:0030036 73 0.010
locomotion GO:0040011 237 0.010
alpha amino acid metabolic process GO:1901605 71 0.010
oxidation reduction process GO:0055114 304 0.010
regulation of cell projection organization GO:0031344 175 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
cold acclimation GO:0009631 1 0.010
regulation of synaptic transmission GO:0050804 141 0.010
intracellular protein transport GO:0006886 79 0.010
nucleoside metabolic process GO:0009116 179 0.010
metal ion transport GO:0030001 289 0.010
regulation of anatomical structure size GO:0090066 135 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
ribose phosphate biosynthetic process GO:0046390 87 0.010
regulation of metanephros development GO:0072215 4 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
peptidyl amino acid modification GO:0018193 126 0.010
epithelium development GO:0060429 96 0.010

Wfdc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.026
inherited metabolic disorder DOID:655 0 0.026
nervous system disease DOID:863 0 0.019
disease of anatomical entity DOID:7 0 0.019
musculoskeletal system disease DOID:17 0 0.011
muscle tissue disease DOID:66 0 0.011
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.010
disease of cellular proliferation DOID:14566 0 0.010