Rattus norvegicus

0 known processes

Dhtkd1

dehydrogenase E1 and transketolase domain containing 1

(Aliases: MGC116097)

Dhtkd1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.216
cellular amino acid metabolic process GO:0006520 107 0.203
alpha amino acid metabolic process GO:1901605 71 0.196
organic acid metabolic process GO:0006082 292 0.183
alpha amino acid catabolic process GO:1901606 20 0.161
cellular amino acid catabolic process GO:0009063 21 0.090
regulation of phosphorylation GO:0042325 248 0.074
oxoacid metabolic process GO:0043436 290 0.071
single organism catabolic process GO:0044712 283 0.070
catabolic process GO:0009056 351 0.070
valine metabolic process GO:0006573 1 0.059
organonitrogen compound catabolic process GO:1901565 179 0.058
regulation of catalytic activity GO:0050790 304 0.052
regulation of cellular amino acid metabolic process GO:0006521 2 0.050
regulation of cellular ketone metabolic process GO:0010565 27 0.049
cellular catabolic process GO:0044248 295 0.047
cellular response to endogenous stimulus GO:0071495 377 0.044
regulation of protein metabolic process GO:0051246 289 0.044
regulation of multicellular organismal development GO:2000026 376 0.043
small molecule catabolic process GO:0044282 59 0.043
cellular amine metabolic process GO:0044106 38 0.043
nucleobase containing small molecule metabolic process GO:0055086 316 0.042
organic substance catabolic process GO:1901575 316 0.042
intracellular signal transduction GO:0035556 314 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.041
positive regulation of cellular biosynthetic process GO:0031328 295 0.041
cofactor metabolic process GO:0051186 95 0.041
branched chain amino acid metabolic process GO:0009081 4 0.040
carbohydrate derivative metabolic process GO:1901135 346 0.040
positive regulation of cellular amine metabolic process GO:0033240 3 0.039
ion transmembrane transport GO:0034220 365 0.039
regulation of cellular amine metabolic process GO:0033238 8 0.038
regulation of phosphate metabolic process GO:0019220 349 0.038
positive regulation of phosphorus metabolic process GO:0010562 262 0.037
amine metabolic process GO:0009308 38 0.036
regulation of phosphorus metabolic process GO:0051174 349 0.035
regulation of molecular function GO:0065009 398 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.034
regulation of cellular protein metabolic process GO:0032268 267 0.034
transmembrane transport GO:0055085 412 0.033
response to extracellular stimulus GO:0009991 380 0.033
positive regulation of cell differentiation GO:0045597 217 0.033
regulation of secretion GO:0051046 224 0.032
protein phosphorylation GO:0006468 345 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
cellular ketone metabolic process GO:0042180 51 0.032
nucleic acid templated transcription GO:0097659 379 0.032
organic cyclic compound catabolic process GO:1901361 175 0.032
mapk cascade GO:0000165 140 0.030
positive regulation of developmental process GO:0051094 283 0.029
purine nucleotide metabolic process GO:0006163 229 0.029
positive regulation of protein metabolic process GO:0051247 178 0.029
neuron development GO:0048666 286 0.028
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.028
heterocycle catabolic process GO:0046700 167 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
regulation of protein modification process GO:0031399 194 0.027
positive regulation of catalytic activity GO:0043085 184 0.027
positive regulation of phosphate metabolic process GO:0045937 262 0.027
cation transport GO:0006812 382 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
neuron differentiation GO:0030182 368 0.026
positive regulation of protein modification process GO:0031401 142 0.026
regulation of rna metabolic process GO:0051252 391 0.025
regulation of cell differentiation GO:0045595 320 0.025
cellular cation homeostasis GO:0030003 180 0.025
organic acid catabolic process GO:0016054 49 0.025
transcription dna templated GO:0006351 377 0.025
carboxylic acid catabolic process GO:0046395 49 0.025
sulfur compound biosynthetic process GO:0044272 19 0.024
regulation of signal transduction GO:0009966 318 0.024
single organism biosynthetic process GO:0044711 342 0.024
purine containing compound metabolic process GO:0072521 253 0.024
regulation of rna biosynthetic process GO:2001141 381 0.024
organophosphate metabolic process GO:0019637 370 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.023
regulation of protein phosphorylation GO:0001932 183 0.023
rna metabolic process GO:0016070 406 0.023
regulation of kinase activity GO:0043549 117 0.023
cellular nitrogen compound catabolic process GO:0044270 163 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
positive regulation of signal transduction GO:0009967 175 0.023
central nervous system development GO:0007417 311 0.022
cellular response to oxygen containing compound GO:1901701 386 0.022
cellular response to stress GO:0033554 269 0.022
positive regulation of molecular function GO:0044093 230 0.022
response to nutrient levels GO:0031667 370 0.022
regulation of nervous system development GO:0051960 264 0.022
response to oxygen levels GO:0070482 265 0.021
neuron projection development GO:0031175 273 0.021
regulation of catabolic process GO:0009894 113 0.021
cellular response to insulin stimulus GO:0032869 81 0.021
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.021
pyrimidine nucleobase catabolic process GO:0006208 3 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.021
regulation of ion transport GO:0043269 245 0.021
lipid metabolic process GO:0006629 283 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
divalent metal ion transport GO:0070838 132 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
positive regulation of kinase activity GO:0033674 77 0.020
regulation of cellular component organization GO:0051128 368 0.020
regulation of transcription dna templated GO:0006355 374 0.019
regulation of mapk cascade GO:0043408 116 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
branched chain amino acid catabolic process GO:0009083 4 0.019
cation homeostasis GO:0055080 195 0.019
programmed cell death GO:0012501 392 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
apoptotic process GO:0006915 381 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
ion homeostasis GO:0050801 212 0.019
serine family amino acid metabolic process GO:0009069 12 0.019
coenzyme metabolic process GO:0006732 86 0.019
regulation of apoptotic process GO:0042981 335 0.019
chemical homeostasis GO:0048878 292 0.019
anion transmembrane transport GO:0098656 77 0.019
cation transmembrane transport GO:0098655 263 0.019
response to alkaloid GO:0043279 132 0.018
response to growth factor GO:0070848 189 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
negative regulation of cell death GO:0060548 229 0.018
homeostatic process GO:0042592 331 0.018
insulin like growth factor receptor signaling pathway GO:0048009 3 0.018
metal ion homeostasis GO:0055065 186 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
reproduction GO:0000003 245 0.017
regulation of transferase activity GO:0051338 123 0.017
cell projection organization GO:0030030 302 0.017
carboxylic acid transport GO:0046942 115 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
nucleotide metabolic process GO:0009117 279 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
ras protein signal transduction GO:0007265 29 0.017
secretion GO:0046903 307 0.017
metal ion transport GO:0030001 289 0.017
regulation of secretion by cell GO:1903530 208 0.017
regulation of membrane potential GO:0042391 110 0.017
regulation of protein kinase activity GO:0045859 105 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
positive regulation of cell development GO:0010720 176 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
response to inorganic substance GO:0010035 377 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
anion transport GO:0006820 178 0.016
positive regulation of fatty acid beta oxidation GO:0032000 4 0.016
brain development GO:0007420 247 0.016
cellular component biogenesis GO:0044085 368 0.016
rna biosynthetic process GO:0032774 380 0.016
macromolecule localization GO:0033036 252 0.016
multi organism reproductive process GO:0044703 262 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
multicellular organism reproduction GO:0032504 233 0.016
nitrogen compound transport GO:0071705 229 0.016
aging GO:0007568 241 0.016
response to purine containing compound GO:0014074 126 0.016
carbohydrate metabolic process GO:0005975 130 0.016
chromosome segregation GO:0007059 2 0.016
regulation of cell development GO:0060284 263 0.015
negative regulation of cell communication GO:0010648 158 0.015
positive regulation of cell communication GO:0010647 271 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
pyrimidine nucleobase metabolic process GO:0006206 8 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
ribonucleoside metabolic process GO:0009119 174 0.015
axis specification GO:0009798 4 0.015
neurological system process GO:0050877 219 0.015
neuronal action potential GO:0019228 35 0.015
response to aluminum ion GO:0010044 10 0.015
positive regulation of catabolic process GO:0009896 78 0.015
regulation of hormone levels GO:0010817 187 0.015
heart morphogenesis GO:0003007 3 0.015
nucleoside metabolic process GO:0009116 179 0.015
response to peptide hormone GO:0043434 278 0.015
enzyme linked receptor protein signaling pathway GO:0007167 116 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.014
glycosyl compound catabolic process GO:1901658 126 0.014
positive regulation of nervous system development GO:0051962 178 0.014
dephosphorylation GO:0016311 98 0.014
fatty acid catabolic process GO:0009062 26 0.014
positive regulation of transferase activity GO:0051347 81 0.014
regulation of cell proliferation GO:0042127 359 0.014
cellular lipid metabolic process GO:0044255 208 0.014
cellular homeostasis GO:0019725 252 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
organic anion transport GO:0015711 132 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
retinal metabolic process GO:0042574 3 0.014
regulation of neuron differentiation GO:0045664 208 0.014
aromatic compound catabolic process GO:0019439 168 0.014
reproductive process GO:0022414 372 0.014
cellular chemical homeostasis GO:0055082 247 0.014
negative regulation of transport GO:0051051 136 0.014
organic acid transport GO:0015849 116 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
regulation of cell projection organization GO:0031344 175 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
peptidyl amino acid modification GO:0018193 126 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
response to metal ion GO:0010038 253 0.013
behavior GO:0007610 205 0.013
regulation of neurogenesis GO:0050767 247 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
cytokine mediated signaling pathway GO:0019221 43 0.013
cell part morphogenesis GO:0032990 123 0.013
response to acid chemical GO:0001101 222 0.013
blood circulation GO:0008015 183 0.013
response to peptide GO:1901652 292 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
regulation of transmembrane transport GO:0034762 122 0.013
cell adhesion GO:0007155 110 0.013
regulation of programmed cell death GO:0043067 341 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
cell cycle checkpoint GO:0000075 2 0.013
regulation of cellular localization GO:0060341 263 0.012
cellular component assembly GO:0022607 360 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
response to carbohydrate GO:0009743 183 0.012
negative regulation of metabolic process GO:0009892 331 0.012
single organism reproductive process GO:0044702 297 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
positive regulation of transport GO:0051050 245 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
purine containing compound catabolic process GO:0072523 138 0.012
regulation of homeostatic process GO:0032844 101 0.012
response to ketone GO:1901654 182 0.012
lipid biosynthetic process GO:0008610 128 0.012
regulation of gtpase activity GO:0043087 57 0.012
multicellular organism growth GO:0035264 1 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
response to monosaccharide GO:0034284 159 0.012
multicellular organismal signaling GO:0035637 44 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
cell type specific apoptotic process GO:0097285 134 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
single organism organelle organization GO:1902589 180 0.011
proteolysis GO:0006508 175 0.011
regulation of neuron projection development GO:0010975 161 0.011
small molecule biosynthetic process GO:0044283 124 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
gtp metabolic process GO:0046039 72 0.011
regulation of locomotion GO:0040012 148 0.011
motor neuron axon guidance GO:0008045 1 0.011
skeletal system development GO:0001501 41 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
regulation of protein serine threonine kinase activity GO:0071900 64 0.011
positive regulation of signaling GO:0023056 270 0.011
response to cytokine GO:0034097 215 0.011
cell cell signaling GO:0007267 335 0.011
action potential GO:0001508 54 0.011
lipid storage GO:0019915 1 0.011
response to glucocorticoid GO:0051384 223 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
head development GO:0060322 247 0.011
transmission of nerve impulse GO:0019226 42 0.011
regulation of lipid metabolic process GO:0019216 68 0.011
response to corticosteroid GO:0031960 235 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
beta alanine metabolic process GO:0019482 3 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
reproductive structure development GO:0048608 128 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
response to decreased oxygen levels GO:0036293 237 0.010
circulatory system process GO:0003013 183 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
gastrulation GO:0007369 2 0.010
regulation of cellular component movement GO:0051270 150 0.010
dendrite development GO:0016358 72 0.010
secretion by cell GO:0032940 248 0.010
regulation of organelle organization GO:0033043 80 0.010
inorganic ion transmembrane transport GO:0098660 229 0.010
positive regulation of gtp catabolic process GO:0033126 48 0.010
positive regulation of cell migration GO:0030335 96 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
monosaccharide metabolic process GO:0005996 61 0.010
kidney development GO:0001822 67 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
positive regulation of protein kinase activity GO:0045860 73 0.010
nucleoside catabolic process GO:0009164 126 0.010
phospholipid metabolic process GO:0006644 61 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
negative regulation of signaling GO:0023057 157 0.010

Dhtkd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.029
inherited metabolic disorder DOID:655 0 0.027
disease of anatomical entity DOID:7 0 0.027
nervous system disease DOID:863 0 0.027
central nervous system disease DOID:331 0 0.013
brain disease DOID:936 0 0.013