Rattus norvegicus

0 known processes

Zic2

Zic family member 2 (odd-paired homolog, Drosophila)

Zic2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 377 0.111
Fly
negative regulation of cellular metabolic process GO:0031324 281 0.077
response to cytokine GO:0034097 215 0.072
transcription from rna polymerase ii promoter GO:0006366 252 0.069
Fly
brain development GO:0007420 247 0.066
positive regulation of rna biosynthetic process GO:1902680 197 0.064
Fly
rna biosynthetic process GO:0032774 380 0.064
Fly
regulation of cellular protein metabolic process GO:0032268 267 0.063
rna metabolic process GO:0016070 406 0.063
Fly
protein phosphorylation GO:0006468 345 0.063
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.058
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.057
positive regulation of nucleic acid templated transcription GO:1903508 197 0.056
Fly
response to biotic stimulus GO:0009607 226 0.055
immune system process GO:0002376 204 0.054
regulation of rna biosynthetic process GO:2001141 381 0.054
Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.053
Fly
negative regulation of apoptotic process GO:0043066 181 0.051
negative regulation of metabolic process GO:0009892 331 0.050
positive regulation of cell communication GO:0010647 271 0.050
regulation of phosphorus metabolic process GO:0051174 349 0.049
cellular component assembly GO:0022607 360 0.048
cognition GO:0050890 92 0.047
positive regulation of gene expression GO:0010628 244 0.047
Fly
positive regulation of response to stimulus GO:0048584 285 0.047
central nervous system development GO:0007417 311 0.047
negative regulation of biosynthetic process GO:0009890 168 0.046
regulation of multicellular organismal development GO:2000026 376 0.046
intracellular signal transduction GO:0035556 314 0.044
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.044
regulation of nucleic acid templated transcription GO:1903506 380 0.044
Fly
regulation of rna metabolic process GO:0051252 391 0.043
Fly
positive regulation of transcription dna templated GO:0045893 197 0.043
Fly
regulation of phosphate metabolic process GO:0019220 349 0.042
cellular component biogenesis GO:0044085 368 0.041
cellular component movement GO:0006928 248 0.041
Fly
response to external biotic stimulus GO:0043207 221 0.041
macromolecular complex subunit organization GO:0043933 339 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
Fly
response to wounding GO:0009611 254 0.040
response to bacterium GO:0009617 200 0.039
regulation of protein metabolic process GO:0051246 289 0.038
regulation of intracellular signal transduction GO:1902531 218 0.038
response to other organism GO:0051707 220 0.038
metal ion homeostasis GO:0055065 186 0.037
nucleic acid templated transcription GO:0097659 379 0.037
Fly
neuron differentiation GO:0030182 368 0.036
reproductive process GO:0022414 372 0.036
Fly
anatomical structure morphogenesis GO:0009653 298 0.036
Fly
positive regulation of biosynthetic process GO:0009891 319 0.036
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
Fly
protein complex assembly GO:0006461 263 0.035
apoptotic process GO:0006915 381 0.034
negative regulation of macromolecule metabolic process GO:0010605 260 0.034
regulation of cellular amino acid metabolic process GO:0006521 2 0.034
regulation of programmed cell death GO:0043067 341 0.032
response to radiation GO:0009314 137 0.032
aging GO:0007568 241 0.031
cellular response to corticosteroid stimulus GO:0071384 69 0.031
cellular response to lipid GO:0071396 201 0.031
multi organism reproductive process GO:0044703 262 0.031
Fly
oxoacid metabolic process GO:0043436 290 0.030
carbohydrate derivative metabolic process GO:1901135 346 0.030
positive regulation of phosphorylation GO:0042327 177 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
Fly
gamete generation GO:0007276 124 0.029
Fly
defense response GO:0006952 194 0.029
programmed cell death GO:0012501 392 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
Fly
negative regulation of cellular biosynthetic process GO:0031327 161 0.027
reproduction GO:0000003 245 0.026
Fly
regulation of neuron differentiation GO:0045664 208 0.026
positive regulation of developmental process GO:0051094 283 0.026
positive regulation of rna metabolic process GO:0051254 203 0.026
Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.026
Fly
regulation of cellular localization GO:0060341 263 0.026
head development GO:0060322 247 0.025
regulation of cell differentiation GO:0045595 320 0.025
regulation of protein modification process GO:0031399 194 0.025
regulation of transcription dna templated GO:0006355 374 0.025
Fly
regulation of cell development GO:0060284 263 0.025
regulation of apoptotic process GO:0042981 335 0.025
regulation of molecular function GO:0065009 398 0.024
positive regulation of signal transduction GO:0009967 175 0.024
negative regulation of multicellular organismal process GO:0051241 203 0.024
negative regulation of gene expression GO:0010629 199 0.024
cellular response to organic cyclic compound GO:0071407 202 0.024
inorganic ion transmembrane transport GO:0098660 229 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.023
cellular amino acid metabolic process GO:0006520 107 0.023
multicellular organism reproduction GO:0032504 233 0.023
Fly
regulation of cellular ketone metabolic process GO:0010565 27 0.023
cellular ketone metabolic process GO:0042180 51 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
regulation of cell proliferation GO:0042127 359 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
cell migration GO:0016477 197 0.022
Fly
epithelial cell differentiation GO:0030855 71 0.022
response to estrogen GO:0043627 232 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.021
cellular response to hormone stimulus GO:0032870 247 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
cellular amine metabolic process GO:0044106 38 0.021
macromolecular complex assembly GO:0065003 273 0.021
amine metabolic process GO:0009308 38 0.021
multi multicellular organism process GO:0044706 138 0.021
regulation of signal transduction GO:0009966 318 0.021
positive regulation of cell death GO:0010942 184 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
single organism reproductive process GO:0044702 297 0.020
Fly
response to metal ion GO:0010038 253 0.020
cellular response to external stimulus GO:0071496 118 0.020
positive regulation of protein modification process GO:0031401 142 0.020
response to inorganic substance GO:0010035 377 0.020
peptidyl amino acid modification GO:0018193 126 0.020
neuron projection development GO:0031175 273 0.019
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.019
metal ion transport GO:0030001 289 0.019
cell morphogenesis involved in differentiation GO:0000904 119 0.019
cation transmembrane transport GO:0098655 263 0.019
ion homeostasis GO:0050801 212 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
positive regulation of intracellular signal transduction GO:1902533 138 0.018
tissue development GO:0009888 252 0.018
response to oxygen levels GO:0070482 265 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
immune response GO:0006955 104 0.017
regulation of cell projection organization GO:0031344 175 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
protein complex subunit organization GO:0071822 302 0.017
positive regulation of protein phosphorylation GO:0001934 135 0.017
cell projection organization GO:0030030 302 0.017
regulation of cellular component organization GO:0051128 368 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
negative regulation of cell death GO:0060548 229 0.016
cellular response to alcohol GO:0097306 87 0.016
vesicle mediated transport GO:0016192 181 0.016
cation transport GO:0006812 382 0.016
positive regulation of molecular function GO:0044093 230 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
response to corticosteroid GO:0031960 235 0.016
regulation of catalytic activity GO:0050790 304 0.016
nucleotide metabolic process GO:0009117 279 0.016
regulation of response to external stimulus GO:0032101 106 0.016
response to hexose GO:0009746 144 0.016
cellular homeostasis GO:0019725 252 0.016
innate immune response GO:0045087 35 0.016
negative regulation of transcription dna templated GO:0045892 116 0.015
protein complex biogenesis GO:0070271 263 0.015
muscle system process GO:0003012 115 0.015
phosphatidylinositol dephosphorylation GO:0046856 4 0.015
chemical homeostasis GO:0048878 292 0.015
catabolic process GO:0009056 351 0.015
response to acid chemical GO:0001101 222 0.015
regulation of transferase activity GO:0051338 123 0.015
mapk cascade GO:0000165 140 0.015
intracellular transport GO:0046907 185 0.015
homeostatic process GO:0042592 331 0.015
response to estradiol GO:0032355 164 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
lipid metabolic process GO:0006629 283 0.015
tube development GO:0035295 89 0.014
Fly
nucleoside phosphate metabolic process GO:0006753 283 0.014
hormone secretion GO:0046879 115 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
ion transmembrane transport GO:0034220 365 0.014
cellular response to oxygen containing compound GO:1901701 386 0.014
ras protein signal transduction GO:0007265 29 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
organic acid metabolic process GO:0006082 292 0.014
developmental process involved in reproduction GO:0003006 159 0.014
regulation of secretion by cell GO:1903530 208 0.014
response to extracellular stimulus GO:0009991 380 0.014
cell type specific apoptotic process GO:0097285 134 0.014
positive regulation of apoptotic process GO:0043065 154 0.013
regeneration GO:0031099 163 0.013
cellular response to stress GO:0033554 269 0.013
regulation of phosphorylation GO:0042325 248 0.013
blood circulation GO:0008015 183 0.013
circulatory system process GO:0003013 183 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
response to carbohydrate GO:0009743 183 0.013
odontogenesis GO:0042476 32 0.013
regulation of response to stress GO:0080134 126 0.013
response to peptide hormone GO:0043434 278 0.013
behavior GO:0007610 205 0.013
regulation of neurogenesis GO:0050767 247 0.013
sexual reproduction GO:0019953 148 0.013
Fly
inorganic cation transmembrane transport GO:0098662 202 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
actin cytoskeleton organization GO:0030036 73 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
regulation of neuron projection development GO:0010975 161 0.013
single organism behavior GO:0044708 130 0.013
cellular catabolic process GO:0044248 295 0.013
cellular response to steroid hormone stimulus GO:0071383 93 0.013
proteolysis GO:0006508 175 0.013
protein localization GO:0008104 191 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
epithelium development GO:0060429 96 0.013
purine nucleotide metabolic process GO:0006163 229 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
response to hypoxia GO:0001666 231 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
negative regulation of molecular function GO:0044092 133 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
female pregnancy GO:0007565 122 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
cell motility GO:0048870 202 0.012
Fly
peptidyl tyrosine modification GO:0018212 72 0.012
regulation of protein kinase activity GO:0045859 105 0.012
male gamete generation GO:0048232 99 0.012
s shaped body morphogenesis GO:0072050 2 0.012
sex differentiation GO:0007548 113 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
response to axon injury GO:0048678 59 0.012
positive regulation of transport GO:0051050 245 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.011
positive regulation of response to external stimulus GO:0032103 51 0.011
cell part morphogenesis GO:0032990 123 0.011
gastrulation GO:0007369 2 0.011
organ formation GO:0048645 3 0.011
wound healing GO:0042060 122 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
carbohydrate homeostasis GO:0033500 75 0.011
positive regulation of signaling GO:0023056 270 0.011
embryonic pattern specification GO:0009880 1 0.011
purine containing compound metabolic process GO:0072521 253 0.011
negative regulation of transport GO:0051051 136 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
cell morphogenesis GO:0000902 142 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
negative regulation of developmental process GO:0051093 125 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
neurological system process GO:0050877 219 0.011
positive regulation of tolerance induction dependent upon immune response GO:0002654 1 0.011
negative regulation of signal transduction GO:0009968 83 0.011
axis specification GO:0009798 4 0.011
single organism cellular localization GO:1902580 102 0.011
regulation of stress activated mapk cascade GO:0032872 23 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
response to decreased oxygen levels GO:0036293 237 0.010
regulation of intracellular transport GO:0032386 65 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
male gonad development GO:0008584 59 0.010
locomotion GO:0040011 237 0.010
Fly
defense response to gram negative bacterium GO:0050829 3 0.010
regulation of nervous system development GO:0051960 264 0.010
response to glucose GO:0009749 136 0.010
divalent inorganic cation transport GO:0072511 134 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
single organism organelle organization GO:1902589 180 0.010
cellular response to peptide GO:1901653 133 0.010
spermatogenesis GO:0007283 99 0.010
positive regulation of nervous system development GO:0051962 178 0.010
sequestering of calcium ion GO:0051208 8 0.010
camp metabolic process GO:0046058 63 0.010

Zic2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.076
nervous system disease DOID:863 0 0.076
sensory system disease DOID:0050155 0 0.023
eye and adnexa disease DOID:1492 0 0.023
gastrointestinal system disease DOID:77 0 0.022
eye disease DOID:5614 0 0.021
retinal disease DOID:5679 0 0.016
retinal degeneration DOID:8466 0 0.016
central nervous system disease DOID:331 0 0.014