Rattus norvegicus

28 known processes

Col1a2

collagen, type I, alpha 2

Col1a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to vitamin e GO:0071306 3 1.000
Rat
growth plate cartilage development GO:0003417 2 0.999
Rat
cellular response to nicotine GO:0071316 7 0.997
Rat
endochondral bone morphogenesis GO:0060350 7 0.996
Rat
cellular response to fluoride GO:1902618 1 0.996
Rat
tooth eruption GO:0044691 1 0.994
Rat
extracellular fibril organization GO:0043206 1 0.993
collagen fibril organization GO:0030199 1 0.990
Human
cartilage development involved in endochondral bone morphogenesis GO:0060351 3 0.963
Rat
embryonic skeletal system development GO:0048706 3 0.941
response to vitamin e GO:0033197 24 0.935
Rat
response to mechanical stimulus GO:0009612 134 0.911
Zebrafish Rat
aorta development GO:0035904 2 0.900
protein heterotrimerization GO:0070208 2 0.877
Mouse
peptide cross linking GO:0018149 1 0.875
cellular response to thyroid hormone stimulus GO:0097067 5 0.857
response to fibroblast growth factor GO:0071774 29 0.843
Rat
cartilage development GO:0051216 22 0.811
Rat
extracellular matrix organization GO:0030198 13 0.752
Human
odontogenesis GO:0042476 32 0.690
Rat
response to norepinephrine GO:0071873 5 0.673
extracellular structure organization GO:0043062 13 0.614
Human
cellular response to retinoic acid GO:0071300 27 0.565
response to corticosteroid GO:0031960 235 0.560
Rat
response to retinoic acid GO:0032526 63 0.555
organ growth GO:0035265 24 0.542
Rat
cellular response to epidermal growth factor stimulus GO:0071364 12 0.532
Rat
artery development GO:0060840 3 0.526
kidney development GO:0001822 67 0.496
tissue development GO:0009888 252 0.490
Rat
response to purine containing compound GO:0014074 126 0.485
Rat
response to camp GO:0051591 91 0.481
Rat
developmental growth involved in morphogenesis GO:0060560 33 0.476
Rat
intramembranous ossification GO:0001957 1 0.463
cellular response to hormone stimulus GO:0032870 247 0.448
wound healing GO:0042060 122 0.447
Rat
response to tumor necrosis factor GO:0034612 56 0.444
Rat
response to monoamine GO:0071867 17 0.427
connective tissue development GO:0061448 33 0.420
Rat
protein complex subunit organization GO:0071822 302 0.415
Human Mouse
bone morphogenesis GO:0060349 11 0.412
Rat
response to estradiol GO:0032355 164 0.406
Rat
response to hyperoxia GO:0055093 45 0.401
Rat
vasculature development GO:0001944 70 0.376
Human
cellular response to alkaloid GO:0071312 25 0.373
Rat
positive regulation of stem cell differentiation GO:2000738 2 0.364
response to estrogen GO:0043627 232 0.352
Rat
cellular response to peptide GO:1901653 133 0.343
Rat
cellular response to acid chemical GO:0071229 75 0.334
response to organophosphorus GO:0046683 102 0.333
Rat
response to peptide GO:1901652 292 0.321
Rat
macromolecular complex subunit organization GO:0043933 339 0.320
Human Mouse
cellular response to cytokine stimulus GO:0071345 127 0.309
Rat
response to inorganic substance GO:0010035 377 0.304
Rat
cellular response to vitamin GO:0071295 21 0.300
Rat
endochondral ossification GO:0001958 2 0.298
renal system development GO:0072001 67 0.295
cellular response to organic cyclic compound GO:0071407 202 0.290
Rat
response to growth factor GO:0070848 189 0.284
Human Rat
skeletal system morphogenesis GO:0048705 12 0.282
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.280
Rat
response to catecholamine GO:0071869 16 0.271
cellular response to tumor necrosis factor GO:0071356 46 0.261
Rat
response to wounding GO:0009611 254 0.250
Rat
response to transforming growth factor beta GO:0071559 46 0.242
Human Rat
cellular response to abiotic stimulus GO:0071214 85 0.240
Rat
eye morphogenesis GO:0048592 4 0.235
cellular response to growth factor stimulus GO:0071363 162 0.230
Human Rat
cellular response to nutrient GO:0031670 30 0.228
Rat
response to increased oxygen levels GO:0036296 45 0.226
Rat
response to oxidative stress GO:0006979 186 0.217
Rat
response to extracellular stimulus GO:0009991 380 0.207
Rat
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.202
Human
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.201
Human Rat
cell motility GO:0048870 202 0.199
response to radiation GO:0009314 137 0.196
Rat
response to ionizing radiation GO:0010212 59 0.191
Rat
response to x ray GO:0010165 15 0.187
Rat
cellular response to endogenous stimulus GO:0071495 377 0.179
elastic fiber assembly GO:0048251 1 0.174
macromolecular complex assembly GO:0065003 273 0.172
Mouse
ossification GO:0001503 70 0.165
Rat
response to cytokine GO:0034097 215 0.164
Rat
aging GO:0007568 241 0.164
Rat
response to epidermal growth factor GO:0070849 18 0.161
Rat
cellular response to mechanical stimulus GO:0071260 48 0.158
Rat
response to external biotic stimulus GO:0043207 221 0.152
growth GO:0040007 165 0.150
Rat
organ morphogenesis GO:0009887 75 0.149
Human Rat
cellular response to external stimulus GO:0071496 118 0.144
Rat
response to reactive oxygen species GO:0000302 120 0.139
Rat
positive regulation of signal transduction GO:0009967 175 0.138
response to thyroid hormone GO:0097066 17 0.131
response to acid chemical GO:0001101 222 0.130
anatomical structure morphogenesis GO:0009653 298 0.130
Human Rat
response to glucocorticoid GO:0051384 223 0.130
skin morphogenesis GO:0043589 2 0.126
Human
regulation of cell differentiation GO:0045595 320 0.121
cellular response to nitrogen compound GO:1901699 210 0.121
Mouse Rat
skeletal system development GO:0001501 41 0.118
Human Rat
response to peptide hormone GO:0043434 278 0.118
Rat
response to fluoride GO:1902617 3 0.115
Rat
protein oligomerization GO:0051259 191 0.114
Mouse
cellular component assembly GO:0022607 360 0.114
Mouse
positive regulation of epithelial to mesenchymal transition GO:0010718 2 0.113
endochondral bone growth GO:0003416 3 0.113
Rat
response to hydrogen peroxide GO:0042542 89 0.107
Rat
response to nutrient levels GO:0031667 370 0.105
Rat
head development GO:0060322 247 0.105
eye development GO:0001654 50 0.103
blood vessel development GO:0001568 69 0.099
Human
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.094
developmental growth GO:0048589 100 0.092
Rat
formation of primary germ layer GO:0001704 1 0.089
cellular response to nutrient levels GO:0031669 60 0.086
Rat
positive regulation of non canonical wnt signaling pathway GO:2000052 1 0.086
response to biotic stimulus GO:0009607 226 0.084
cell substrate adhesion GO:0031589 29 0.083
cellular response to organonitrogen compound GO:0071417 197 0.083
Mouse Rat
cellular response to lipid GO:0071396 201 0.081
bone development GO:0060348 25 0.081
Rat
urogenital system development GO:0001655 78 0.079
response to nicotine GO:0035094 51 0.079
Rat
protein complex biogenesis GO:0070271 263 0.078
Mouse
negative regulation of multicellular organismal process GO:0051241 203 0.078
digestive tract morphogenesis GO:0048546 8 0.076
regulation of locomotion GO:0040012 148 0.074
tube development GO:0035295 89 0.073
response to oxygen levels GO:0070482 265 0.073
Rat
cellular response to oxygen containing compound GO:1901701 386 0.072
muscle organ development GO:0007517 50 0.072
cerebral cortex development GO:0021987 18 0.071
regulation of signal transduction GO:0009966 318 0.070
response to nutrient GO:0007584 248 0.069
Rat
protein heterooligomerization GO:0051291 89 0.068
Mouse
circulatory system development GO:0072359 134 0.067
Human
gastrulation GO:0007369 2 0.067
regulation of epithelial to mesenchymal transition GO:0010717 2 0.066
protein complex assembly GO:0006461 263 0.064
Mouse
transcription from rna polymerase ii promoter GO:0006366 252 0.063
positive regulation of developmental process GO:0051094 283 0.062
synaptic vesicle endocytosis GO:0048488 4 0.061
developmental process involved in reproduction GO:0003006 159 0.061
muscle tissue development GO:0060537 58 0.061
embryo development GO:0009790 49 0.058
muscle structure development GO:0061061 87 0.058
positive regulation of rna metabolic process GO:0051254 203 0.057
wnt signaling pathway GO:0016055 17 0.057
response to vitamin GO:0033273 131 0.056
Rat
cell morphogenesis GO:0000902 142 0.056
cellular component movement GO:0006928 248 0.055
camera type eye morphogenesis GO:0048593 2 0.054
cellular response to metal ion GO:0071248 55 0.054
positive regulation of gene expression GO:0010628 244 0.054
regulation of cell motility GO:2000145 131 0.053
digestive system development GO:0055123 41 0.053
response to alkaloid GO:0043279 132 0.053
Rat
cell adhesion GO:0007155 110 0.053
cardiovascular system development GO:0072358 134 0.053
Human
chondrocyte differentiation GO:0002062 10 0.052
Rat
regulation of rna biosynthetic process GO:2001141 381 0.052
integrin mediated signaling pathway GO:0007229 7 0.052
placenta development GO:0001890 22 0.050
response to amino acid GO:0043200 75 0.050
Mouse
positive regulation of cell communication GO:0010647 271 0.049
positive regulation of response to stimulus GO:0048584 285 0.049
reproductive process GO:0022414 372 0.047
positive regulation of cellular component movement GO:0051272 102 0.047
response to molecule of bacterial origin GO:0002237 194 0.047
positive regulation of cell differentiation GO:0045597 217 0.046
digestive tract development GO:0048565 39 0.045
cellular response to extracellular stimulus GO:0031668 73 0.044
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.043
localization of cell GO:0051674 202 0.043
response to glucose GO:0009749 136 0.043
anatomical structure formation involved in morphogenesis GO:0048646 83 0.042
regulation of cellular component movement GO:0051270 150 0.042
appendage morphogenesis GO:0035107 4 0.042
reproductive structure development GO:0048608 128 0.041
nucleic acid templated transcription GO:0097659 379 0.041
defecation GO:0030421 1 0.041
tissue remodeling GO:0048771 40 0.041
regulation of nucleic acid templated transcription GO:1903506 380 0.039
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.039
response to interleukin 2 GO:0070669 1 0.039
rna biosynthetic process GO:0032774 380 0.039
response to monosaccharide GO:0034284 159 0.039
biological adhesion GO:0022610 110 0.038
cell migration GO:0016477 197 0.038
rna metabolic process GO:0016070 406 0.038
bmp signaling pathway GO:0030509 4 0.037
wound healing spreading of cells GO:0044319 2 0.037
striated muscle tissue development GO:0014706 58 0.036
negative regulation of developmental process GO:0051093 125 0.036
regulation of cell migration GO:0030334 128 0.036
positive regulation of cellular biosynthetic process GO:0031328 295 0.036
response to other organism GO:0051707 220 0.035
locomotion GO:0040011 237 0.034
response to hexose GO:0009746 144 0.034
lipid biosynthetic process GO:0008610 128 0.034
visual perception GO:0007601 3 0.034
regulation of cell development GO:0060284 263 0.033
positive regulation of nucleic acid templated transcription GO:1903508 197 0.033
reproductive system development GO:0061458 128 0.033
kidney vasculature development GO:0061440 6 0.032
regulation of anatomical structure morphogenesis GO:0022603 141 0.032
cellular response to interleukin 2 GO:0071352 1 0.032
positive regulation of locomotion GO:0040017 102 0.032
muscle organ morphogenesis GO:0048644 1 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
response to metal ion GO:0010038 253 0.031
positive regulation of signaling GO:0023056 270 0.030
negative regulation of neurogenesis GO:0050768 78 0.030
skin development GO:0043588 17 0.029
Human
brain development GO:0007420 247 0.029
multicellular organismal macromolecule metabolic process GO:0044259 21 0.028
stem cell differentiation GO:0048863 16 0.028
direct ossification GO:0036072 1 0.027
positive regulation of biosynthetic process GO:0009891 319 0.026
protein transport GO:0015031 132 0.026
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.026
Human
central nervous system development GO:0007417 311 0.026
positive regulation of transcription dna templated GO:0045893 197 0.025
s shaped body morphogenesis GO:0072050 2 0.025
regulation of nervous system development GO:0051960 264 0.025
tissue regeneration GO:0042246 36 0.025
multicellular organism reproduction GO:0032504 233 0.025
regulation of ossification GO:0030278 32 0.024
establishment of protein localization GO:0045184 141 0.024
response to starvation GO:0042594 59 0.024
intracellular signal transduction GO:0035556 314 0.024
Human
proteolysis GO:0006508 175 0.024
cell morphogenesis involved in differentiation GO:0000904 119 0.024
osteoblast differentiation GO:0001649 26 0.024
single organism reproductive process GO:0044702 297 0.024
regulation of cellular component organization GO:0051128 368 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
cellular component biogenesis GO:0044085 368 0.021
Mouse
sensory perception of light stimulus GO:0050953 3 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
replacement ossification GO:0036075 2 0.021
tissue morphogenesis GO:0048729 22 0.021
muscle tissue morphogenesis GO:0060415 1 0.021
organic acid metabolic process GO:0006082 292 0.021
blood vessel morphogenesis GO:0048514 58 0.021
morphogenesis of an epithelium GO:0002009 20 0.021
rho protein signal transduction GO:0007266 11 0.020
Human
cell projection organization GO:0030030 302 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
macromolecule localization GO:0033036 252 0.020
female pregnancy GO:0007565 122 0.019
multicellular organismal metabolic process GO:0044236 22 0.019
cellular response to fibroblast growth factor stimulus GO:0044344 24 0.019
Rat
regulation of catalytic activity GO:0050790 304 0.019
steroid biosynthetic process GO:0006694 48 0.019
forebrain development GO:0030900 98 0.019
pro t cell differentiation GO:0002572 1 0.018
regulation of b cell differentiation GO:0045577 1 0.018
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.018
ras protein signal transduction GO:0007265 29 0.018
Human
skeletal muscle tissue development GO:0007519 31 0.018
reproduction GO:0000003 245 0.018
regulation of neuron migration GO:2001222 2 0.018
astrocyte development GO:0014002 4 0.018
cellular macromolecule localization GO:0070727 122 0.017
multi organism reproductive process GO:0044703 262 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
neuron projection development GO:0031175 273 0.017
single organism biosynthetic process GO:0044711 342 0.017
negative regulation of cell development GO:0010721 82 0.017
hormone metabolic process GO:0042445 69 0.016
comma shaped body morphogenesis GO:0072049 2 0.016
cellular ketone metabolic process GO:0042180 51 0.016
cell matrix adhesion GO:0007160 19 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
negative regulation of neuron death GO:1901215 69 0.016
endocrine hormone secretion GO:0060986 21 0.015
positive regulation of multicellular organismal process GO:0051240 387 0.015
protein phosphorylation GO:0006468 345 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
negative regulation of cell proliferation GO:0008285 119 0.015
protein localization to organelle GO:0033365 57 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
peptidyl amino acid modification GO:0018193 126 0.015
regulation of protein metabolic process GO:0051246 289 0.015
neuron death GO:0070997 127 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
regulation of embryonic development GO:0045995 2 0.015
positive regulation of axon guidance GO:1902669 3 0.014
regulation of apoptotic process GO:0042981 335 0.014
regulation of ras protein signal transduction GO:0046578 45 0.014
sensory organ development GO:0007423 74 0.014
morphogenesis of an epithelial sheet GO:0002011 2 0.014
oxoacid metabolic process GO:0043436 290 0.014
immune system process GO:0002376 204 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
transcription dna templated GO:0006351 377 0.013
gastric motility GO:0035482 3 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
cellular response to glucocorticoid stimulus GO:0071385 68 0.013
positive regulation of phosphorylation GO:0042327 177 0.012
positive regulation of molecular function GO:0044093 230 0.012
positive regulation of cell development GO:0010720 176 0.012
regulation of protein modification process GO:0031399 194 0.012
development of primary sexual characteristics GO:0045137 107 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
positive regulation of protein modification process GO:0031401 142 0.012
response to carbohydrate GO:0009743 183 0.012
development of primary male sexual characteristics GO:0046546 59 0.012
sulfur compound metabolic process GO:0006790 70 0.012
triglyceride homeostasis GO:0070328 2 0.012
apoptotic process GO:0006915 381 0.012
regulation of transferase activity GO:0051338 123 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
multicellular organismal catabolic process GO:0044243 2 0.011
regulation of transcription dna templated GO:0006355 374 0.011
regulation of lipid metabolic process GO:0019216 68 0.011
positive regulation of transferase activity GO:0051347 81 0.011
regeneration GO:0031099 163 0.011
cellular amine metabolic process GO:0044106 38 0.011
regulation of secretion by cell GO:1903530 208 0.011
regulation of hydrolase activity GO:0051336 143 0.011
gamete generation GO:0007276 124 0.011
regulation of stem cell differentiation GO:2000736 2 0.010
positive regulation of cell death GO:0010942 184 0.010
response to high light intensity GO:0009644 1 0.010
locomotory exploration behavior GO:0035641 1 0.010
schwann cell migration GO:0036135 2 0.010
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 5 0.010
organelle organization GO:0006996 266 0.010

Col1a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
collagen disease DOID:854 0 0.973
ehlers danlos syndrome DOID:13359 0 0.973
disease of anatomical entity DOID:7 0 0.973
Human
musculoskeletal system disease DOID:17 0 0.973
Human
connective tissue disease DOID:65 0 0.973
Human
osteochondrodysplasia DOID:2256 0 0.874
Human
bone development disease DOID:0080006 0 0.874
Human
bone disease DOID:0080001 0 0.874
Human
osteogenesis imperfecta DOID:12347 0 0.198
Human
muscular disease DOID:0080000 0 0.014
myopathy DOID:423 0 0.013
muscular dystrophy DOID:9884 0 0.013
muscle tissue disease DOID:66 0 0.013
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010