Rattus norvegicus

46 known processes

Eef1a1

eukaryotic translation elongation factor 1 alpha 1

(Aliases: Eef1a2l1,EEF-1,Eef1a2,EEF1A,SI,EF1A,MGC125172)

Eef1a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.100
cellular catabolic process GO:0044248 295 0.079
nucleotide metabolic process GO:0009117 279 0.076
nucleoside triphosphate metabolic process GO:0009141 144 0.074
nucleoside phosphate metabolic process GO:0006753 283 0.074
purine nucleotide metabolic process GO:0006163 229 0.073
regulation of phosphorus metabolic process GO:0051174 349 0.072
nucleoside triphosphate catabolic process GO:0009143 123 0.072
carboxylic acid metabolic process GO:0019752 289 0.071
purine containing compound metabolic process GO:0072521 253 0.068
organic acid metabolic process GO:0006082 292 0.067
ribonucleotide metabolic process GO:0009259 231 0.066
catabolic process GO:0009056 351 0.062
organic substance catabolic process GO:1901575 316 0.061
ribose phosphate metabolic process GO:0019693 235 0.061
ribonucleotide catabolic process GO:0009261 136 0.061
heterocycle catabolic process GO:0046700 167 0.060
organophosphate metabolic process GO:0019637 370 0.059
regulation of phosphate metabolic process GO:0019220 349 0.059
purine ribonucleotide metabolic process GO:0009150 227 0.059
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.056
ribonucleoside metabolic process GO:0009119 174 0.055
regulation of cellular protein metabolic process GO:0032268 267 0.054
glycosyl compound metabolic process GO:1901657 182 0.054
positive regulation of phosphorus metabolic process GO:0010562 262 0.054
carbohydrate derivative metabolic process GO:1901135 346 0.053
regulation of cell migration GO:0030334 128 0.052
nucleoside metabolic process GO:0009116 179 0.052
regulation of cell proliferation GO:0042127 359 0.051
aromatic compound catabolic process GO:0019439 168 0.051
purine nucleoside triphosphate metabolic process GO:0009144 141 0.050
positive regulation of phosphate metabolic process GO:0045937 262 0.050
ribonucleoside catabolic process GO:0042454 126 0.048
intracellular signal transduction GO:0035556 314 0.048
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.048
nucleobase containing small molecule metabolic process GO:0055086 316 0.048
purine nucleoside monophosphate metabolic process GO:0009126 84 0.046
nucleoside monophosphate metabolic process GO:0009123 93 0.046
protein localization GO:0008104 191 0.046
single organism catabolic process GO:0044712 283 0.045
purine ribonucleoside metabolic process GO:0046128 168 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
positive regulation of cellular protein metabolic process GO:0032270 167 0.043
heart morphogenesis GO:0003007 3 0.043
cellular nitrogen compound catabolic process GO:0044270 163 0.043
programmed cell death GO:0012501 392 0.042
purine nucleoside catabolic process GO:0006152 124 0.042
cellular amino acid metabolic process GO:0006520 107 0.041
apoptotic process GO:0006915 381 0.040
purine ribonucleoside catabolic process GO:0046130 124 0.040
purine nucleoside monophosphate catabolic process GO:0009128 55 0.040
ribonucleoside triphosphate metabolic process GO:0009199 141 0.040
purine ribonucleotide catabolic process GO:0009154 136 0.039
purine nucleoside metabolic process GO:0042278 169 0.039
atp metabolic process GO:0046034 72 0.039
aging GO:0007568 241 0.039
regulation of multicellular organismal development GO:2000026 376 0.039
oxoacid metabolic process GO:0043436 290 0.038
nucleoside phosphate catabolic process GO:1901292 140 0.038
organelle organization GO:0006996 266 0.038
regulation of catalytic activity GO:0050790 304 0.038
cellular component biogenesis GO:0044085 368 0.038
purine nucleoside triphosphate catabolic process GO:0009146 122 0.037
immune system process GO:0002376 204 0.037
regulation of protein metabolic process GO:0051246 289 0.037
organic cyclic compound catabolic process GO:1901361 175 0.037
small gtpase mediated signal transduction GO:0007264 36 0.036
organophosphate catabolic process GO:0046434 148 0.036
neuron projection development GO:0031175 273 0.036
regulation of neurogenesis GO:0050767 247 0.035
regulation of nervous system development GO:0051960 264 0.035
cellular response to oxygen containing compound GO:1901701 386 0.035
ras protein signal transduction GO:0007265 29 0.035
positive regulation of cell development GO:0010720 176 0.035
atp catabolic process GO:0006200 54 0.035
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.034
cell cell signaling GO:0007267 335 0.034
regulation of molecular function GO:0065009 398 0.034
lipid metabolic process GO:0006629 283 0.033
macromolecule localization GO:0033036 252 0.033
Yeast
cation transport GO:0006812 382 0.033
purine nucleotide catabolic process GO:0006195 136 0.033
cell projection organization GO:0030030 302 0.032
positive regulation of cell proliferation GO:0008284 249 0.032
neuron differentiation GO:0030182 368 0.032
regulation of rna metabolic process GO:0051252 391 0.032
protein complex assembly GO:0006461 263 0.032
locomotion GO:0040011 237 0.032
nucleobase containing compound catabolic process GO:0034655 152 0.031
ribonucleoside triphosphate catabolic process GO:0009203 122 0.031
single organism reproductive process GO:0044702 297 0.031
localization of cell GO:0051674 202 0.031
positive regulation of protein metabolic process GO:0051247 178 0.031
carbohydrate derivative catabolic process GO:1901136 147 0.031
cellular response to endogenous stimulus GO:0071495 377 0.031
Human
regulation of neuron differentiation GO:0045664 208 0.031
regulation of signal transduction GO:0009966 318 0.030
negative regulation of response to stimulus GO:0048585 155 0.030
rna metabolic process GO:0016070 406 0.030
multi organism reproductive process GO:0044703 262 0.030
head development GO:0060322 247 0.030
positive regulation of signaling GO:0023056 270 0.030
response to alkaloid GO:0043279 132 0.029
ribonucleoside monophosphate metabolic process GO:0009161 88 0.029
purine containing compound catabolic process GO:0072523 138 0.029
regulation of phosphorylation GO:0042325 248 0.029
nucleotide catabolic process GO:0009166 139 0.029
cellular ketone metabolic process GO:0042180 51 0.029
cellular component assembly GO:0022607 360 0.029
organonitrogen compound catabolic process GO:1901565 179 0.029
reproductive process GO:0022414 372 0.029
synaptic transmission GO:0007268 235 0.028
regulation of protein modification process GO:0031399 194 0.028
regeneration GO:0031099 163 0.028
leukocyte activation GO:0045321 76 0.028
negative regulation of cellular metabolic process GO:0031324 281 0.028
regulation of nucleic acid templated transcription GO:1903506 380 0.027
homeostatic process GO:0042592 331 0.027
neuron development GO:0048666 286 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
nucleoside monophosphate catabolic process GO:0009125 56 0.027
nucleoside catabolic process GO:0009164 126 0.026
regulation of hydrolase activity GO:0051336 143 0.026
multicellular organismal reproductive process GO:0048609 233 0.026
regulation of cell projection organization GO:0031344 175 0.025
cellular component movement GO:0006928 248 0.025
organic anion transport GO:0015711 132 0.025
intracellular transport GO:0046907 185 0.025
Yeast
blood circulation GO:0008015 183 0.024
cellular amine metabolic process GO:0044106 38 0.024
ribonucleoside monophosphate catabolic process GO:0009158 55 0.024
reproduction GO:0000003 245 0.024
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.024
cellular chemical homeostasis GO:0055082 247 0.024
cellular calcium ion homeostasis GO:0006874 160 0.024
response to metal ion GO:0010038 253 0.024
nucleic acid templated transcription GO:0097659 379 0.024
response to extracellular stimulus GO:0009991 380 0.023
regulation of cellular component organization GO:0051128 368 0.023
negative regulation of multicellular organismal process GO:0051241 203 0.023
macromolecular complex assembly GO:0065003 273 0.023
positive regulation of signal transduction GO:0009967 175 0.023
guanosine containing compound metabolic process GO:1901068 74 0.023
regulation of cell development GO:0060284 263 0.023
regulation of locomotion GO:0040012 148 0.023
response to nutrient levels GO:0031667 370 0.023
positive regulation of developmental process GO:0051094 283 0.023
rna biosynthetic process GO:0032774 380 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
ion transmembrane transport GO:0034220 365 0.022
negative regulation of metabolic process GO:0009892 331 0.022
protein complex biogenesis GO:0070271 263 0.022
response to oxidative stress GO:0006979 186 0.022
regulation of apoptotic process GO:0042981 335 0.022
amine metabolic process GO:0009308 38 0.022
metal ion transport GO:0030001 289 0.022
positive regulation of neurogenesis GO:0050769 165 0.021
cellular homeostasis GO:0019725 252 0.021
regulation of secretion by cell GO:1903530 208 0.021
multicellular organism reproduction GO:0032504 233 0.021
vesicle mediated transport GO:0016192 181 0.021
regulation of secretion GO:0051046 224 0.021
transmembrane transport GO:0055085 412 0.021
regulation of transcription dna templated GO:0006355 374 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
regulation of nucleotide metabolic process GO:0006140 117 0.020
secretion by cell GO:0032940 248 0.020
positive regulation of cellular catabolic process GO:0031331 71 0.020
positive regulation of transport GO:0051050 245 0.020
regulation of cell differentiation GO:0045595 320 0.020
positive regulation of cell communication GO:0010647 271 0.020
response to cocaine GO:0042220 39 0.020
metal ion homeostasis GO:0055065 186 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
negative regulation of cell death GO:0060548 229 0.020
carboxylic acid transport GO:0046942 115 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
single organism organelle organization GO:1902589 180 0.019
positive regulation of nucleotide metabolic process GO:0045981 91 0.019
negative regulation of gene expression GO:0010629 199 0.019
cellular cation homeostasis GO:0030003 180 0.019
nitrogen compound transport GO:0071705 229 0.019
Yeast
proteolysis GO:0006508 175 0.019
regulation of rna biosynthetic process GO:2001141 381 0.019
negative regulation of cell communication GO:0010648 158 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
organic acid transport GO:0015849 116 0.019
regulation of hormone levels GO:0010817 187 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
response to peptide GO:1901652 292 0.019
positive regulation of cellular component organization GO:0051130 200 0.018
maintenance of location GO:0051235 17 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
regulation of catabolic process GO:0009894 113 0.018
regulation of ion transport GO:0043269 245 0.018
chemical homeostasis GO:0048878 292 0.018
glycosyl compound catabolic process GO:1901658 126 0.018
gamete generation GO:0007276 124 0.018
central nervous system development GO:0007417 311 0.018
regulation of peptide hormone secretion GO:0090276 80 0.018
anion transport GO:0006820 178 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
membrane organization GO:0061024 94 0.017
cell migration GO:0016477 197 0.017
response to wounding GO:0009611 254 0.017
calcium ion homeostasis GO:0055074 162 0.017
cellular response to stress GO:0033554 269 0.017
regulation of membrane potential GO:0042391 110 0.017
regulation of neuron projection development GO:0010975 161 0.017
positive regulation of gene expression GO:0010628 244 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
single organism intracellular transport GO:1902582 166 0.017
Yeast
receptor metabolic process GO:0043112 18 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
regulation of cellular localization GO:0060341 263 0.017
cellular macromolecule localization GO:0070727 122 0.017
g protein coupled receptor signaling pathway GO:0007186 242 0.017
regulation of system process GO:0044057 208 0.017
alternative mrna splicing via spliceosome GO:0000380 4 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
regulation of programmed cell death GO:0043067 341 0.016
response to lipopolysaccharide GO:0032496 191 0.016
regulation of cell motility GO:2000145 131 0.016
chromosome segregation GO:0007059 2 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
transcription dna templated GO:0006351 377 0.016
response to nicotine GO:0035094 51 0.016
response to molecule of bacterial origin GO:0002237 194 0.016
hormone transport GO:0009914 121 0.016
brain development GO:0007420 247 0.016
response to peptide hormone GO:0043434 278 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
signal release GO:0023061 145 0.015
response to reactive oxygen species GO:0000302 120 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
response to corticosteroid GO:0031960 235 0.015
response to glucocorticoid GO:0051384 223 0.015
negative regulation of nervous system development GO:0051961 79 0.015
positive regulation of protein modification process GO:0031401 142 0.015
coenzyme metabolic process GO:0006732 86 0.015
positive regulation of molecular function GO:0044093 230 0.015
asymmetric protein localization GO:0008105 2 0.015
protein phosphorylation GO:0006468 345 0.015
secretion GO:0046903 307 0.015
cell cycle GO:0007049 101 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
response to glucose GO:0009749 136 0.015
response to growth factor GO:0070848 189 0.015
Human
cellular response to hormone stimulus GO:0032870 247 0.015
fatty acid metabolic process GO:0006631 99 0.015
regulation of nucleotide catabolic process GO:0030811 65 0.014
response to ammonium ion GO:0060359 71 0.014
anterior posterior pattern specification GO:0009952 1 0.014
regulation of cellular component movement GO:0051270 150 0.014
amino acid transport GO:0006865 70 0.014
positive regulation of catabolic process GO:0009896 78 0.014
hormone secretion GO:0046879 115 0.014
cell type specific apoptotic process GO:0097285 134 0.014
cation homeostasis GO:0055080 195 0.014
sexual reproduction GO:0019953 148 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
regulation of cell activation GO:0050865 50 0.014
negative regulation of transport GO:0051051 136 0.014
cellular ion homeostasis GO:0006873 184 0.014
male gamete generation GO:0048232 99 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
protein complex subunit organization GO:0071822 302 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
positive regulation of nucleoside metabolic process GO:0045979 55 0.014
axis specification GO:0009798 4 0.014
negative regulation of developmental process GO:0051093 125 0.014
negative regulation of signaling GO:0023057 157 0.014
response to monosaccharide GO:0034284 159 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
gtp catabolic process GO:0006184 71 0.014
ion homeostasis GO:0050801 212 0.014
organ regeneration GO:0031100 101 0.013
single organism membrane organization GO:0044802 74 0.013
cellular lipid metabolic process GO:0044255 208 0.013
hormone metabolic process GO:0042445 69 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
peptide hormone secretion GO:0030072 84 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
regulation of immune system process GO:0002682 123 0.013
regulation of response to external stimulus GO:0032101 106 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
response to hexose GO:0009746 144 0.013
negative regulation of cell development GO:0010721 82 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
Human
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
sex differentiation GO:0007548 113 0.013
cation transmembrane transport GO:0098655 263 0.013
response to carbohydrate GO:0009743 183 0.013
gtp metabolic process GO:0046039 72 0.013
cellular response to peptide GO:1901653 133 0.013
cardiac chamber development GO:0003205 1 0.013
gland development GO:0048732 155 0.013
protein oligomerization GO:0051259 191 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
behavior GO:0007610 205 0.013
guanosine containing compound catabolic process GO:1901069 71 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
response to ketone GO:1901654 182 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
negative regulation of molecular function GO:0044092 133 0.012
bmp signaling pathway GO:0030509 4 0.012
female pregnancy GO:0007565 122 0.012
regulation of response to stress GO:0080134 126 0.012
cytoplasmic transport GO:0016482 115 0.012
Yeast
divalent inorganic cation homeostasis GO:0072507 165 0.012
circulatory system process GO:0003013 183 0.012
positive regulation of nucleotide catabolic process GO:0030813 53 0.012
meiotic cell cycle process GO:1903046 3 0.012
response to nutrient GO:0007584 248 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.012
muscle contraction GO:0006936 88 0.012
lipid storage GO:0019915 1 0.012
eye morphogenesis GO:0048592 4 0.012
divalent inorganic cation transport GO:0072511 134 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
regulation of hormone secretion GO:0046883 106 0.012
sequestering of calcium ion GO:0051208 8 0.012
spermatogenesis GO:0007283 99 0.012
single organism cellular localization GO:1902580 102 0.012
response to acid chemical GO:0001101 222 0.012
developmental process involved in reproduction GO:0003006 159 0.012
regulation of vesicle mediated transport GO:0060627 81 0.011
embryonic pattern specification GO:0009880 1 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
regulation of purine nucleotide catabolic process GO:0033121 65 0.011
single organism behavior GO:0044708 130 0.011
response to cytokine GO:0034097 215 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
protein heterooligomerization GO:0051291 89 0.011
regulation of anatomical structure size GO:0090066 135 0.011
response to estrogen GO:0043627 232 0.011
positive regulation of immune system process GO:0002684 90 0.011
response to hydrogen peroxide GO:0042542 89 0.011
positive regulation of nervous system development GO:0051962 178 0.011
cell activation GO:0001775 97 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
organic hydroxy compound transport GO:0015850 77 0.011
dna metabolic process GO:0006259 96 0.011
cellular amide metabolic process GO:0043603 44 0.011
calcium ion transport GO:0006816 131 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
cellular response to glucocorticoid stimulus GO:0071385 68 0.011
regulation of metal ion transport GO:0010959 118 0.011
rna localization GO:0006403 4 0.011
Yeast
cyclic nucleotide metabolic process GO:0009187 80 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
gastrulation GO:0007369 2 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
regulation of blood circulation GO:1903522 110 0.011
response to external biotic stimulus GO:0043207 221 0.011
regulation of camp metabolic process GO:0030814 43 0.010
regulation of peptide secretion GO:0002791 82 0.010
negative regulation of neuron death GO:1901215 69 0.010
development of primary sexual characteristics GO:0045137 107 0.010
regulation of synaptic transmission GO:0050804 141 0.010
defense response GO:0006952 194 0.010
tissue development GO:0009888 252 0.010
negative regulation of rna metabolic process GO:0051253 123 0.010
embryonic axis specification GO:0000578 1 0.010
inorganic ion transmembrane transport GO:0098660 229 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
regulation of erk1 and erk2 cascade GO:0070372 41 0.010
positive regulation of hydrolase activity GO:0051345 86 0.010
anatomical structure morphogenesis GO:0009653 298 0.010
regulation of neuron death GO:1901214 115 0.010
regulation of mapk cascade GO:0043408 116 0.010
sequestering of metal ion GO:0051238 9 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
positive regulation of secretion by cell GO:1903532 128 0.010
response to estradiol GO:0032355 164 0.010
spindle organization GO:0007051 2 0.010
transcription from rna polymerase ii promoter GO:0006366 252 0.010
camp metabolic process GO:0046058 63 0.010

Eef1a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
musculoskeletal system disease DOID:17 0 0.017
cardiovascular system disease DOID:1287 0 0.014
muscular disease DOID:0080000 0 0.012
nervous system disease DOID:863 0 0.011
heart disease DOID:114 0 0.011
muscle tissue disease DOID:66 0 0.011
gastrointestinal system disease DOID:77 0 0.011
disease of metabolism DOID:0014667 0 0.011