Rattus norvegicus

0 known processes

Mlana

melan-A

Mlana biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to stress GO:0033554 269 0.155
regulation of cell differentiation GO:0045595 320 0.152
neuron differentiation GO:0030182 368 0.140
cation transport GO:0006812 382 0.130
regulation of secretion GO:0051046 224 0.126
tissue development GO:0009888 252 0.123
head development GO:0060322 247 0.121
cell migration GO:0016477 197 0.113
neuron development GO:0048666 286 0.108
brain development GO:0007420 247 0.104
cellular component movement GO:0006928 248 0.099
central nervous system development GO:0007417 311 0.097
nucleic acid templated transcription GO:0097659 379 0.094
carboxylic acid metabolic process GO:0019752 289 0.094
regulation of rna metabolic process GO:0051252 391 0.090
reproductive process GO:0022414 372 0.090
multi multicellular organism process GO:0044706 138 0.089
regulation of locomotion GO:0040012 148 0.088
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.088
regulation of rna biosynthetic process GO:2001141 381 0.085
transcription from rna polymerase ii promoter GO:0006366 252 0.082
oxoacid metabolic process GO:0043436 290 0.081
locomotion GO:0040011 237 0.081
organic acid metabolic process GO:0006082 292 0.080
programmed cell death GO:0012501 392 0.079
response to inorganic substance GO:0010035 377 0.077
cellular component assembly GO:0022607 360 0.075
organophosphate metabolic process GO:0019637 370 0.073
regulation of multicellular organismal development GO:2000026 376 0.067
regulation of apoptotic process GO:0042981 335 0.065
regulation of nucleic acid templated transcription GO:1903506 380 0.065
response to decreased oxygen levels GO:0036293 237 0.065
anion transport GO:0006820 178 0.064
cell projection organization GO:0030030 302 0.064
negative regulation of multicellular organismal process GO:0051241 203 0.060
regulation of phosphate metabolic process GO:0019220 349 0.060
immune system process GO:0002376 204 0.060
rna metabolic process GO:0016070 406 0.057
cellular component biogenesis GO:0044085 368 0.056
cell cell signaling GO:0007267 335 0.055
eye morphogenesis GO:0048592 4 0.055
cellular response to organic cyclic compound GO:0071407 202 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.053
regulation of phosphorus metabolic process GO:0051174 349 0.052
cellular response to cytokine stimulus GO:0071345 127 0.052
regulation of cellular component organization GO:0051128 368 0.051
positive regulation of multicellular organismal process GO:0051240 387 0.049
negative regulation of rna biosynthetic process GO:1902679 118 0.049
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.048
signal release GO:0023061 145 0.047
positive regulation of secretion GO:0051047 140 0.046
catabolic process GO:0009056 351 0.045
response to interleukin 1 GO:0070555 55 0.045
regulation of transcription dna templated GO:0006355 374 0.045
positive regulation of cell death GO:0010942 184 0.045
regulation of cell proliferation GO:0042127 359 0.044
response to estrogen GO:0043627 232 0.043
regulation of nervous system development GO:0051960 264 0.042
regulation of programmed cell death GO:0043067 341 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.042
sexual reproduction GO:0019953 148 0.041
regulation of secretion by cell GO:1903530 208 0.041
positive regulation of rna biosynthetic process GO:1902680 197 0.040
regulation of cellular localization GO:0060341 263 0.040
inflammatory response GO:0006954 150 0.040
secretion GO:0046903 307 0.040
positive regulation of biosynthetic process GO:0009891 319 0.039
positive regulation of transport GO:0051050 245 0.039
response to glucocorticoid GO:0051384 223 0.038
cellular ketone metabolic process GO:0042180 51 0.038
response to lipopolysaccharide GO:0032496 191 0.038
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.038
negative regulation of cell differentiation GO:0045596 99 0.038
transcription dna templated GO:0006351 377 0.038
multicellular organismal reproductive process GO:0048609 233 0.038
carboxylic acid transport GO:0046942 115 0.037
metal ion transport GO:0030001 289 0.037
response to hypoxia GO:0001666 231 0.037
regulation of cell development GO:0060284 263 0.036
chemotaxis GO:0006935 66 0.036
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.036
regulation of cellular component movement GO:0051270 150 0.036
camera type eye development GO:0043010 48 0.036
localization of cell GO:0051674 202 0.036
positive regulation of developmental process GO:0051094 283 0.035
anatomical structure morphogenesis GO:0009653 298 0.035
response to calcium ion GO:0051592 59 0.035
nitrogen compound transport GO:0071705 229 0.035
positive regulation of response to wounding GO:1903036 34 0.035
aging GO:0007568 241 0.035
positive regulation of apoptotic process GO:0043065 154 0.035
positive regulation of transcription dna templated GO:0045893 197 0.034
negative regulation of biosynthetic process GO:0009890 168 0.034
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
regulation of cell motility GO:2000145 131 0.034
negative regulation of transcription dna templated GO:0045892 116 0.034
negative regulation of cell communication GO:0010648 158 0.034
cellular response to lipid GO:0071396 201 0.034
developmental process involved in reproduction GO:0003006 159 0.033
female pregnancy GO:0007565 122 0.033
negative regulation of cell development GO:0010721 82 0.033
glycosyl compound metabolic process GO:1901657 182 0.033
response to nutrient levels GO:0031667 370 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.033
multicellular organism reproduction GO:0032504 233 0.033
response to peptide GO:1901652 292 0.033
negative regulation of cellular biosynthetic process GO:0031327 161 0.032
defense response GO:0006952 194 0.032
reproduction GO:0000003 245 0.032
telencephalon development GO:0021537 62 0.032
organic anion transport GO:0015711 132 0.031
regulation of saliva secretion GO:0046877 3 0.031
cellular response to alcohol GO:0097306 87 0.031
heterocycle catabolic process GO:0046700 167 0.030
positive regulation of cellular component organization GO:0051130 200 0.030
positive regulation of cell differentiation GO:0045597 217 0.030
response to growth factor GO:0070848 189 0.030
response to cytokine GO:0034097 215 0.030
glycosyl compound catabolic process GO:1901658 126 0.030
carbohydrate derivative metabolic process GO:1901135 346 0.029
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.029
multi organism reproductive process GO:0044703 262 0.029
transmembrane transport GO:0055085 412 0.028
amide transport GO:0042886 105 0.028
regulation of cytokine production GO:0001817 56 0.028
regulation of response to stress GO:0080134 126 0.028
secretion by cell GO:0032940 248 0.028
phototransduction visible light GO:0007603 2 0.028
regulation of phosphorylation GO:0042325 248 0.028
gonad development GO:0008406 104 0.028
nucleoside metabolic process GO:0009116 179 0.027
response to carbohydrate GO:0009743 183 0.027
regulation of neurogenesis GO:0050767 247 0.027
regulation of small gtpase mediated signal transduction GO:0051056 48 0.027
vasculature development GO:0001944 70 0.027
regulation of anatomical structure morphogenesis GO:0022603 141 0.027
cellular catabolic process GO:0044248 295 0.026
cellular homeostasis GO:0019725 252 0.026
vesicle mediated transport GO:0016192 181 0.026
response to metal ion GO:0010038 253 0.026
response to peptide hormone GO:0043434 278 0.026
organelle organization GO:0006996 266 0.026
regulation of amine transport GO:0051952 54 0.025
guanosine containing compound catabolic process GO:1901069 71 0.025
g protein coupled receptor signaling pathway GO:0007186 242 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
single organism reproductive process GO:0044702 297 0.025
positive regulation of cell development GO:0010720 176 0.025
response to oxygen levels GO:0070482 265 0.025
response to corticosteroid GO:0031960 235 0.024
single organism organelle organization GO:1902589 180 0.024
forebrain development GO:0030900 98 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
peptide secretion GO:0002790 86 0.024
hormone secretion GO:0046879 115 0.024
regulation of cell projection organization GO:0031344 175 0.024
regulation of vesicle mediated transport GO:0060627 81 0.024
regulation of neuron projection development GO:0010975 161 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
regulation of hormone levels GO:0010817 187 0.023
homeostatic process GO:0042592 331 0.023
rna biosynthetic process GO:0032774 380 0.023
peptide transport GO:0015833 97 0.023
apoptotic process GO:0006915 381 0.023
negative regulation of gene expression GO:0010629 199 0.023
negative regulation of secretion by cell GO:1903531 72 0.023
calcium ion transport GO:0006816 131 0.023
angiogenesis GO:0001525 53 0.023
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
negative regulation of metabolic process GO:0009892 331 0.022
divalent inorganic cation transport GO:0072511 134 0.022
neurological system process GO:0050877 219 0.022
positive regulation of programmed cell death GO:0043068 157 0.022
positive regulation of gene expression GO:0010628 244 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
cell motility GO:0048870 202 0.022
protein complex subunit organization GO:0071822 302 0.022
intracellular signal transduction GO:0035556 314 0.022
response to extracellular stimulus GO:0009991 380 0.022
myeloid cell differentiation GO:0030099 22 0.022
peptide hormone secretion GO:0030072 84 0.022
positive regulation of peptide hormone secretion GO:0090277 50 0.022
neuron projection development GO:0031175 273 0.021
cellular response to organonitrogen compound GO:0071417 197 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
ribose phosphate metabolic process GO:0019693 235 0.021
cellular response to abiotic stimulus GO:0071214 85 0.021
single organism catabolic process GO:0044712 283 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
cell activation GO:0001775 97 0.021
regulation of molecular function GO:0065009 398 0.021
negative regulation of signaling GO:0023057 157 0.021
positive regulation of hormone secretion GO:0046887 65 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
regulation of cellular ketone metabolic process GO:0010565 27 0.020
cellular response to ketone GO:1901655 51 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
regulation of calcium ion transport GO:0051924 77 0.020
embryonic pattern specification GO:0009880 1 0.020
insulin secretion GO:0030073 69 0.020
regulation of hydrolase activity GO:0051336 143 0.020
response to wounding GO:0009611 254 0.020
regulation of system process GO:0044057 208 0.020
negative regulation of apoptotic process GO:0043066 181 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
ribonucleoside metabolic process GO:0009119 174 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
purine nucleotide metabolic process GO:0006163 229 0.019
sensory perception GO:0007600 101 0.019
development of primary sexual characteristics GO:0045137 107 0.019
response to estradiol GO:0032355 164 0.019
dopamine secretion GO:0014046 15 0.019
organic substance catabolic process GO:1901575 316 0.019
response to osmotic stress GO:0006970 42 0.019
regulation of cell migration GO:0030334 128 0.019
acid secretion GO:0046717 48 0.019
cellular chemical homeostasis GO:0055082 247 0.019
positive regulation of peptide secretion GO:0002793 52 0.019
monosaccharide metabolic process GO:0005996 61 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
response to dexamethasone GO:0071548 49 0.018
regulation of hormone secretion GO:0046883 106 0.018
positive regulation of neurogenesis GO:0050769 165 0.018
maternal process involved in female pregnancy GO:0060135 38 0.018
gamete generation GO:0007276 124 0.018
cytokine production GO:0001816 61 0.018
regulation of catalytic activity GO:0050790 304 0.018
positive regulation of secretion by cell GO:1903532 128 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.018
response to reactive oxygen species GO:0000302 120 0.018
cell growth GO:0016049 104 0.018
nucleoside phosphate catabolic process GO:1901292 140 0.018
behavior GO:0007610 205 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
acute inflammatory response GO:0002526 58 0.017
reproductive system development GO:0061458 128 0.017
blood vessel development GO:0001568 69 0.017
regeneration GO:0031099 163 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
regulation of catecholamine secretion GO:0050433 32 0.017
response to alkaloid GO:0043279 132 0.017
dephosphorylation GO:0016311 98 0.017
response to vitamin GO:0033273 131 0.017
positive regulation of protein metabolic process GO:0051247 178 0.016
reproductive structure development GO:0048608 128 0.016
sensory organ development GO:0007423 74 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
response to hexose GO:0009746 144 0.016
synaptic transmission gabaergic GO:0051932 22 0.016
regulation of insulin secretion GO:0050796 65 0.016
sodium ion transport GO:0006814 82 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
purine containing compound metabolic process GO:0072521 253 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
negative regulation of response to external stimulus GO:0032102 37 0.016
cellular response to lipopolysaccharide GO:0071222 55 0.016
regulation of response to wounding GO:1903034 69 0.016
single organism biosynthetic process GO:0044711 342 0.016
regulation of peptide transport GO:0090087 87 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.015
ras protein signal transduction GO:0007265 29 0.015
regulation of signal transduction GO:0009966 318 0.015
blood vessel morphogenesis GO:0048514 58 0.015
amine metabolic process GO:0009308 38 0.015
diencephalon development GO:0021536 21 0.015
anterior posterior pattern specification GO:0009952 1 0.015
protein complex biogenesis GO:0070271 263 0.015
ion homeostasis GO:0050801 212 0.015
response to temperature stimulus GO:0009266 94 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
development of primary female sexual characteristics GO:0046545 56 0.015
response to acid chemical GO:0001101 222 0.015
sex differentiation GO:0007548 113 0.015
regulation of response to external stimulus GO:0032101 106 0.015
leukocyte activation GO:0045321 76 0.015
guanosine containing compound metabolic process GO:1901068 74 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
female gonad development GO:0008585 53 0.015
positive regulation of phagocytosis engulfment GO:0060100 4 0.015
regulation of protein metabolic process GO:0051246 289 0.014
hormone transport GO:0009914 121 0.014
carbohydrate catabolic process GO:0016052 40 0.014
amino acid transport GO:0006865 70 0.014
response to toxic substance GO:0009636 133 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
ovulation cycle process GO:0022602 50 0.014
regulation of chemotaxis GO:0050920 29 0.014
cognition GO:0050890 92 0.014
regulation of defense response GO:0031347 68 0.014
rhythmic process GO:0048511 156 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
calcium ion transport into cytosol GO:0060402 38 0.014
response to external biotic stimulus GO:0043207 221 0.014
macromolecular complex assembly GO:0065003 273 0.014
cellular response to metal ion GO:0071248 55 0.014
response to histamine GO:0034776 3 0.014
positive regulation of molecular function GO:0044093 230 0.014
proteolysis GO:0006508 175 0.014
response to nicotine GO:0035094 51 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
cellular amino acid metabolic process GO:0006520 107 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
response to oxidative stress GO:0006979 186 0.014
cation homeostasis GO:0055080 195 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.014
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.013
cellular response to molecule of bacterial origin GO:0071219 56 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
cardiovascular system development GO:0072358 134 0.013
response to insulin GO:0032868 133 0.013
retinal metabolic process GO:0042574 3 0.013
positive regulation of immune system process GO:0002684 90 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.013
cell type specific apoptotic process GO:0097285 134 0.013
biological adhesion GO:0022610 110 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
regulation of protein modification process GO:0031399 194 0.013
amine transport GO:0015837 57 0.013
inner ear morphogenesis GO:0042472 1 0.013
axis specification GO:0009798 4 0.013
renal system development GO:0072001 67 0.013
negative regulation of neuron differentiation GO:0045665 62 0.013
detection of stimulus GO:0051606 24 0.013
negative regulation of transport GO:0051051 136 0.013
nucleotide metabolic process GO:0009117 279 0.013
positive regulation of cell communication GO:0010647 271 0.013
synaptic transmission GO:0007268 235 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
negative regulation of nervous system development GO:0051961 79 0.013
interleukin 1 mediated signaling pathway GO:0070498 2 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
calcium ion homeostasis GO:0055074 162 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
oxidation reduction process GO:0055114 304 0.013
tube development GO:0035295 89 0.013
gastrulation GO:0007369 2 0.013
tube morphogenesis GO:0035239 23 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
erythrocyte differentiation GO:0030218 1 0.013
organic acid transport GO:0015849 116 0.013
receptor metabolic process GO:0043112 18 0.012
positive regulation of cell migration GO:0030335 96 0.012
positive regulation of protein modification process GO:0031401 142 0.012
immune response GO:0006955 104 0.012
gtp catabolic process GO:0006184 71 0.012
protein oligomerization GO:0051259 191 0.012
negative regulation of developmental process GO:0051093 125 0.012
response to glucose GO:0009749 136 0.012
regulation of ion transport GO:0043269 245 0.012
positive regulation of neuron apoptotic process GO:0043525 33 0.012
heart development GO:0007507 72 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
regulation of neuron differentiation GO:0045664 208 0.012
regulation of metal ion transport GO:0010959 118 0.012
camera type eye morphogenesis GO:0048593 2 0.012
actin cytoskeleton organization GO:0030036 73 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
negative regulation of amine transport GO:0051953 24 0.012
ion transmembrane transport GO:0034220 365 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
vascular process in circulatory system GO:0003018 96 0.012
positive regulation of calcium ion transport GO:0051928 36 0.012
response to testosterone GO:0033574 55 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
negative regulation of secretion GO:0051048 82 0.012
gliogenesis GO:0042063 93 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
response to ketone GO:1901654 182 0.012
retina development in camera type eye GO:0060041 27 0.012
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
regulation of nucleoside metabolic process GO:0009118 66 0.012
memory GO:0007613 54 0.011
protein phosphorylation GO:0006468 345 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
urogenital system development GO:0001655 78 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
urinary bladder smooth muscle contraction GO:0014832 4 0.011
platelet aggregation GO:0070527 4 0.011
positive regulation of neuron death GO:1901216 43 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
regulation of peptide secretion GO:0002791 82 0.011
muscle system process GO:0003012 115 0.011
kidney development GO:0001822 67 0.011
epithelium development GO:0060429 96 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
microglial cell activation GO:0001774 14 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
embryonic appendage morphogenesis GO:0035113 4 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
cellular response to low density lipoprotein particle stimulus GO:0071404 3 0.011
second messenger mediated signaling GO:0019932 51 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.011
rho protein signal transduction GO:0007266 11 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
cation transmembrane transport GO:0098655 263 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.010
alcohol metabolic process GO:0006066 77 0.010
limbic system development GO:0021761 38 0.010
cellular response to nitrogen compound GO:1901699 210 0.010
single organism carbohydrate catabolic process GO:0044724 40 0.010
metal ion homeostasis GO:0055065 186 0.010
cgmp biosynthetic process GO:0006182 15 0.010
kidney epithelium development GO:0072073 19 0.010
positive regulation of inflammatory response GO:0050729 24 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
embryonic limb morphogenesis GO:0030326 4 0.010
cellular amine metabolic process GO:0044106 38 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
regulation of immune system process GO:0002682 123 0.010
positive regulation of nervous system development GO:0051962 178 0.010
single organism behavior GO:0044708 130 0.010
positive regulation of phosphorylation GO:0042327 177 0.010

Mlana disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.054
disease of anatomical entity DOID:7 0 0.054
nervous system disease DOID:863 0 0.054
eye and adnexa disease DOID:1492 0 0.036
eye disease DOID:5614 0 0.032
retinal disease DOID:5679 0 0.026
retinal degeneration DOID:8466 0 0.026
musculoskeletal system disease DOID:17 0 0.023
immune system disease DOID:2914 0 0.010