Rattus norvegicus

0 known processes

Aars2

alanyl-tRNA synthetase 2, mitochondrial (putative)

(Aliases: AlaRS,Aarsl)

Aars2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of rna biosynthetic process GO:2001141 381 0.089
regulation of nucleic acid templated transcription GO:1903506 380 0.086
nucleic acid templated transcription GO:0097659 379 0.063
rna biosynthetic process GO:0032774 380 0.061
rna metabolic process GO:0016070 406 0.058
Human Rat
transcription dna templated GO:0006351 377 0.056
regulation of rna metabolic process GO:0051252 391 0.051
regulation of signal transduction GO:0009966 318 0.049
regulation of cell differentiation GO:0045595 320 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
organic acid metabolic process GO:0006082 292 0.041
Human Rat
positive regulation of transcription dna templated GO:0045893 197 0.039
negative regulation of gene expression GO:0010629 199 0.038
neuron differentiation GO:0030182 368 0.038
regulation of transcription dna templated GO:0006355 374 0.037
central nervous system development GO:0007417 311 0.037
brain development GO:0007420 247 0.036
oxoacid metabolic process GO:0043436 290 0.036
Human Rat
transcription from rna polymerase ii promoter GO:0006366 252 0.035
carboxylic acid metabolic process GO:0019752 289 0.035
Human Rat
cellular response to oxygen containing compound GO:1901701 386 0.034
negative regulation of macromolecule metabolic process GO:0010605 260 0.034
anterior posterior pattern specification GO:0009952 1 0.034
positive regulation of rna metabolic process GO:0051254 203 0.033
head development GO:0060322 247 0.033
single organism biosynthetic process GO:0044711 342 0.033
Human
intracellular signal transduction GO:0035556 314 0.031
tissue development GO:0009888 252 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
regulation of cell development GO:0060284 263 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.029
negative regulation of metabolic process GO:0009892 331 0.029
negative regulation of transcription dna templated GO:0045892 116 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
protein complex subunit organization GO:0071822 302 0.029
Human
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
carbohydrate metabolic process GO:0005975 130 0.028
cellular component biogenesis GO:0044085 368 0.028
Human
single organism catabolic process GO:0044712 283 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
cellular component assembly GO:0022607 360 0.027
Human
cellular homeostasis GO:0019725 252 0.027
apoptotic process GO:0006915 381 0.027
multicellular organism reproduction GO:0032504 233 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
organic substance catabolic process GO:1901575 316 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
catabolic process GO:0009056 351 0.026
eye morphogenesis GO:0048592 4 0.026
reproductive process GO:0022414 372 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
positive regulation of signal transduction GO:0009967 175 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
regulation of apoptotic process GO:0042981 335 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
cellular amine metabolic process GO:0044106 38 0.024
single organism reproductive process GO:0044702 297 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
Human Rat
negative regulation of rna biosynthetic process GO:1902679 118 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
neuron projection development GO:0031175 273 0.024
positive regulation of gene expression GO:0010628 244 0.024
protein complex assembly GO:0006461 263 0.023
Human
cellular catabolic process GO:0044248 295 0.023
response to acid chemical GO:0001101 222 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
Human
positive regulation of rna biosynthetic process GO:1902680 197 0.023
positive regulation of signaling GO:0023056 270 0.022
cellular response to peptide GO:1901653 133 0.022
non canonical wnt signaling pathway GO:0035567 3 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
programmed cell death GO:0012501 392 0.022
amine metabolic process GO:0009308 38 0.021
macromolecular complex assembly GO:0065003 273 0.021
Human
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
multi organism reproductive process GO:0044703 262 0.021
regulation of molecular function GO:0065009 398 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
regulation of neuron differentiation GO:0045664 208 0.021
negative regulation of rna metabolic process GO:0051253 123 0.021
proteolysis GO:0006508 175 0.021
axis specification GO:0009798 4 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
regulation of programmed cell death GO:0043067 341 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
organophosphate metabolic process GO:0019637 370 0.019
reproduction GO:0000003 245 0.019
organelle organization GO:0006996 266 0.019
Human
response to decreased oxygen levels GO:0036293 237 0.019
tube development GO:0035295 89 0.019
anatomical structure formation involved in morphogenesis GO:0048646 83 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
positive regulation of cell death GO:0010942 184 0.019
regulation of cellular component organization GO:0051128 368 0.019
regulation of multicellular organismal development GO:2000026 376 0.019
cardiovascular system development GO:0072358 134 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
regulation of phosphorylation GO:0042325 248 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
regulation of protein metabolic process GO:0051246 289 0.018
ras protein signal transduction GO:0007265 29 0.018
homeostatic process GO:0042592 331 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
regulation of nervous system development GO:0051960 264 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
response to nutrient levels GO:0031667 370 0.017
cellular response to lipid GO:0071396 201 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
protein localization GO:0008104 191 0.017
embryonic pattern specification GO:0009880 1 0.017
negative regulation of cell communication GO:0010648 158 0.017
heterocycle catabolic process GO:0046700 167 0.017
gastrulation GO:0007369 2 0.017
regulation of cellular localization GO:0060341 263 0.017
sexual reproduction GO:0019953 148 0.017
regulation of neuron projection development GO:0010975 161 0.017
cellular ketone metabolic process GO:0042180 51 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
cell migration GO:0016477 197 0.017
regulation of protein modification process GO:0031399 194 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
regulation of neurogenesis GO:0050767 247 0.016
negative regulation of signaling GO:0023057 157 0.016
purine containing compound metabolic process GO:0072521 253 0.016
cellular response to stress GO:0033554 269 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
positive regulation of molecular function GO:0044093 230 0.016
nucleotide metabolic process GO:0009117 279 0.016
developmental process involved in reproduction GO:0003006 159 0.016
response to oxygen levels GO:0070482 265 0.016
protein phosphorylation GO:0006468 345 0.016
cellular chemical homeostasis GO:0055082 247 0.016
response to metal ion GO:0010038 253 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
coenzyme metabolic process GO:0006732 86 0.016
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
response to inorganic substance GO:0010035 377 0.015
heart morphogenesis GO:0003007 3 0.015
positive regulation of intracellular signal transduction GO:1902533 138 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
gamete generation GO:0007276 124 0.015
peptidyl amino acid modification GO:0018193 126 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
chromosome segregation GO:0007059 2 0.015
positive regulation of developmental process GO:0051094 283 0.015
establishment of tissue polarity GO:0007164 2 0.015
muscle structure development GO:0061061 87 0.015
establishment of protein localization GO:0045184 141 0.015
chemical homeostasis GO:0048878 292 0.015
protein complex biogenesis GO:0070271 263 0.015
Human
response to nutrient GO:0007584 248 0.015
epithelium development GO:0060429 96 0.015
response to retinoic acid GO:0032526 63 0.015
regulation of cell proliferation GO:0042127 359 0.015
regulation of fat cell differentiation GO:0045598 3 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
morphogenesis of embryonic epithelium GO:0016331 3 0.014
aromatic compound catabolic process GO:0019439 168 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
protein oligomerization GO:0051259 191 0.014
cellular cation homeostasis GO:0030003 180 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
single organism intracellular transport GO:1902582 166 0.014
secretion GO:0046903 307 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
metal ion homeostasis GO:0055065 186 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
calcium ion homeostasis GO:0055074 162 0.014
cellular component movement GO:0006928 248 0.014
regulation of establishment of planar polarity GO:0090175 2 0.013
small molecule biosynthetic process GO:0044283 124 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
locomotion GO:0040011 237 0.013
response to peptide hormone GO:0043434 278 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
multicellular organism growth GO:0035264 1 0.013
macromolecule localization GO:0033036 252 0.013
cell cell signaling GO:0007267 335 0.013
axon development GO:0061564 96 0.013
response to hypoxia GO:0001666 231 0.013
response to extracellular stimulus GO:0009991 380 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
maintenance of location GO:0051235 17 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
cellular ion homeostasis GO:0006873 184 0.013
intracellular transport GO:0046907 185 0.013
positive regulation of nervous system development GO:0051962 178 0.013
positive regulation of catalytic activity GO:0043085 184 0.012
ion homeostasis GO:0050801 212 0.012
negative regulation of transport GO:0051051 136 0.012
neurological system process GO:0050877 219 0.012
regulation of system process GO:0044057 208 0.012
single organism organelle organization GO:1902589 180 0.012
Human
ribonucleoside metabolic process GO:0009119 174 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
dna metabolic process GO:0006259 96 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
sensory organ development GO:0007423 74 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
regulation of catalytic activity GO:0050790 304 0.012
lipid storage GO:0019915 1 0.012
positive regulation of cell development GO:0010720 176 0.012
neural crest cell differentiation GO:0014033 2 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
response to peptide GO:1901652 292 0.012
mechanoreceptor differentiation GO:0042490 2 0.012
camera type eye morphogenesis GO:0048593 2 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
cell cycle GO:0007049 101 0.012
nucleoside metabolic process GO:0009116 179 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
circulatory system development GO:0072359 134 0.011
positive regulation of cell communication GO:0010647 271 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
male sex differentiation GO:0046661 64 0.011
response to oxidative stress GO:0006979 186 0.011
limb morphogenesis GO:0035108 4 0.011
cardiac chamber development GO:0003205 1 0.011
negative regulation of cell development GO:0010721 82 0.011
protein transport GO:0015031 132 0.011
response to glucose GO:0009749 136 0.011
cellular protein localization GO:0034613 122 0.011
response to vitamin GO:0033273 131 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
cell projection organization GO:0030030 302 0.011
cofactor metabolic process GO:0051186 95 0.011
rho protein signal transduction GO:0007266 11 0.011
mapk cascade GO:0000165 140 0.011
cation homeostasis GO:0055080 195 0.011
aging GO:0007568 241 0.011
cellular response to alcohol GO:0097306 87 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
adult locomotory behavior GO:0008344 4 0.011
lipid metabolic process GO:0006629 283 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
response to other organism GO:0051707 220 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.011
response to hexose GO:0009746 144 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
neuron development GO:0048666 286 0.011
urogenital system development GO:0001655 78 0.010
cell part morphogenesis GO:0032990 123 0.010
cell type specific apoptotic process GO:0097285 134 0.010
response to purine containing compound GO:0014074 126 0.010
sex differentiation GO:0007548 113 0.010
response to ketone GO:1901654 182 0.010
regulation of stem cell differentiation GO:2000736 2 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
embryonic skeletal system morphogenesis GO:0048704 3 0.010
multicellular organismal signaling GO:0035637 44 0.010
spermatogenesis GO:0007283 99 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
male gamete generation GO:0048232 99 0.010
appendage morphogenesis GO:0035107 4 0.010
embryo development GO:0009790 49 0.010
gland development GO:0048732 155 0.010

Aars2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
sensory system disease DOID:0050155 0 0.013
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
disease of metabolism DOID:0014667 0 0.011
organ system cancer DOID:0050686 0 0.010
eye and adnexa disease DOID:1492 0 0.010
musculoskeletal system disease DOID:17 0 0.010