Rattus norvegicus

0 known processes

Leo1

Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

(Aliases: MGC95290)

Leo1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of metabolic process GO:0009892 331 0.116
regulation of phosphorus metabolic process GO:0051174 349 0.052
rna biosynthetic process GO:0032774 380 0.050
rna metabolic process GO:0016070 406 0.049
brain development GO:0007420 247 0.048
macromolecular complex subunit organization GO:0043933 339 0.044
regulation of molecular function GO:0065009 398 0.042
positive regulation of phosphorus metabolic process GO:0010562 262 0.041
regulation of cellular ketone metabolic process GO:0010565 27 0.040
regulation of multicellular organismal development GO:2000026 376 0.039
reproductive process GO:0022414 372 0.039
regulation of neuron differentiation GO:0045664 208 0.038
regulation of cellular amino acid metabolic process GO:0006521 2 0.037
cellular response to stress GO:0033554 269 0.037
cellular amine metabolic process GO:0044106 38 0.036
transcription dna templated GO:0006351 377 0.036
macromolecule localization GO:0033036 252 0.036
regulation of protein metabolic process GO:0051246 289 0.035
head development GO:0060322 247 0.034
proteolysis GO:0006508 175 0.033
regulation of nervous system development GO:0051960 264 0.033
positive regulation of protein metabolic process GO:0051247 178 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.032
regulation of catalytic activity GO:0050790 304 0.032
central nervous system development GO:0007417 311 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
organelle organization GO:0006996 266 0.030
regulation of phosphate metabolic process GO:0019220 349 0.030
organophosphate metabolic process GO:0019637 370 0.030
protein phosphorylation GO:0006468 345 0.030
nucleic acid templated transcription GO:0097659 379 0.030
negative regulation of cellular metabolic process GO:0031324 281 0.029
regulation of cell projection organization GO:0031344 175 0.029
cellular component movement GO:0006928 248 0.029
single organism biosynthetic process GO:0044711 342 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.029
protein complex subunit organization GO:0071822 302 0.029
positive regulation of phosphate metabolic process GO:0045937 262 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.029
protein complex assembly GO:0006461 263 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.029
positive regulation of cellular protein metabolic process GO:0032270 167 0.028
positive regulation of nervous system development GO:0051962 178 0.027
response to nutrient levels GO:0031667 370 0.027
reproduction GO:0000003 245 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
regulation of signal transduction GO:0009966 318 0.026
cellular protein localization GO:0034613 122 0.026
sexual reproduction GO:0019953 148 0.026
negative regulation of gene expression GO:0010629 199 0.026
cellular component assembly GO:0022607 360 0.026
heterocycle catabolic process GO:0046700 167 0.026
neuron projection development GO:0031175 273 0.026
oxoacid metabolic process GO:0043436 290 0.025
negative regulation of molecular function GO:0044092 133 0.025
response to extracellular stimulus GO:0009991 380 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
amine metabolic process GO:0009308 38 0.025
regulation of neuron projection development GO:0010975 161 0.025
positive regulation of molecular function GO:0044093 230 0.025
single organism carbohydrate metabolic process GO:0044723 118 0.024
positive regulation of phosphorylation GO:0042327 177 0.024
regulation of neurogenesis GO:0050767 247 0.024
response to biotic stimulus GO:0009607 226 0.024
cellular component biogenesis GO:0044085 368 0.024
double strand break repair GO:0006302 1 0.024
response to inorganic substance GO:0010035 377 0.024
cellular ketone metabolic process GO:0042180 51 0.023
cell motility GO:0048870 202 0.023
nucleotide metabolic process GO:0009117 279 0.023
protein complex biogenesis GO:0070271 263 0.023
single organism intracellular transport GO:1902582 166 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.022
neuron differentiation GO:0030182 368 0.022
apoptotic process GO:0006915 381 0.022
growth GO:0040007 165 0.022
multicellular organism reproduction GO:0032504 233 0.022
enzyme linked receptor protein signaling pathway GO:0007167 116 0.022
regulation of apoptotic process GO:0042981 335 0.022
regulation of phosphorylation GO:0042325 248 0.022
intracellular signal transduction GO:0035556 314 0.022
neuron development GO:0048666 286 0.022
carboxylic acid metabolic process GO:0019752 289 0.021
response to metal ion GO:0010038 253 0.021
organonitrogen compound biosynthetic process GO:1901566 167 0.021
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
positive regulation of developmental process GO:0051094 283 0.021
response to peptide GO:1901652 292 0.021
reproductive system development GO:0061458 128 0.021
multi organism reproductive process GO:0044703 262 0.021
regulation of cell differentiation GO:0045595 320 0.021
purine nucleotide metabolic process GO:0006163 229 0.020
regulation of cellular localization GO:0060341 263 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
regulation of cellular component organization GO:0051128 368 0.020
organic acid metabolic process GO:0006082 292 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
cell projection organization GO:0030030 302 0.020
positive regulation of cell development GO:0010720 176 0.020
protein localization GO:0008104 191 0.019
negative regulation of response to stimulus GO:0048585 155 0.019
action potential GO:0001508 54 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
anatomical structure morphogenesis GO:0009653 298 0.019
regulation of membrane potential GO:0042391 110 0.019
regulation of protein modification process GO:0031399 194 0.019
gamete generation GO:0007276 124 0.019
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.019
purine containing compound metabolic process GO:0072521 253 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
heart morphogenesis GO:0003007 3 0.019
cell migration GO:0016477 197 0.019
developmental process involved in reproduction GO:0003006 159 0.019
regulation of system process GO:0044057 208 0.018
single organism organelle organization GO:1902589 180 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
regulation of nucleic acid templated transcription GO:1903506 380 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
development of primary sexual characteristics GO:0045137 107 0.018
cellular homeostasis GO:0019725 252 0.018
negative regulation of apoptotic process GO:0043066 181 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
catabolic process GO:0009056 351 0.017
macromolecular complex assembly GO:0065003 273 0.017
positive regulation of transport GO:0051050 245 0.017
gonad development GO:0008406 104 0.017
regulation of cell development GO:0060284 263 0.017
dna metabolic process GO:0006259 96 0.017
negative regulation of developmental process GO:0051093 125 0.017
organophosphate biosynthetic process GO:0090407 143 0.017
positive regulation of protein modification process GO:0031401 142 0.017
organic cyclic compound catabolic process GO:1901361 175 0.017
regulation of rna metabolic process GO:0051252 391 0.017
localization of cell GO:0051674 202 0.017
cellular catabolic process GO:0044248 295 0.017
regulation of transcription dna templated GO:0006355 374 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
synaptic growth at neuromuscular junction GO:0051124 1 0.017
peptidyl tyrosine modification GO:0018212 72 0.016
regulation of cell motility GO:2000145 131 0.016
immune response GO:0006955 104 0.016
nitrogen compound transport GO:0071705 229 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
organic substance catabolic process GO:1901575 316 0.016
transmembrane transport GO:0055085 412 0.016
cytoplasmic transport GO:0016482 115 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
single organism catabolic process GO:0044712 283 0.016
ras protein signal transduction GO:0007265 29 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
positive regulation of neuron projection development GO:0010976 99 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
programmed cell death GO:0012501 392 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
sex differentiation GO:0007548 113 0.015
regulation of cell migration GO:0030334 128 0.015
multicellular organismal signaling GO:0035637 44 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
intracellular transport GO:0046907 185 0.015
neurological system process GO:0050877 219 0.015
ion transmembrane transport GO:0034220 365 0.015
positive regulation of signaling GO:0023056 270 0.015
negative regulation of cell death GO:0060548 229 0.015
signal release GO:0023061 145 0.015
cellular macromolecule localization GO:0070727 122 0.015
locomotion GO:0040011 237 0.015
carbohydrate metabolic process GO:0005975 130 0.015
cellular response to oxygen containing compound GO:1901701 386 0.015
transmission of nerve impulse GO:0019226 42 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
regulation of growth GO:0040008 105 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
response to oxidative stress GO:0006979 186 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
reproductive structure development GO:0048608 128 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
negative regulation of signal transduction GO:0009968 83 0.014
mrna metabolic process GO:0016071 20 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
peptidyl amino acid modification GO:0018193 126 0.014
regulation of cell proliferation GO:0042127 359 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
cation transport GO:0006812 382 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
lipid metabolic process GO:0006629 283 0.013
positive regulation of cell communication GO:0010647 271 0.013
single organism reproductive process GO:0044702 297 0.013
response to other organism GO:0051707 220 0.013
ncrna processing GO:0034470 3 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
cell cycle GO:0007049 101 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
rna localization GO:0006403 4 0.013
cellular lipid metabolic process GO:0044255 208 0.013
cytoskeleton organization GO:0007010 111 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
homeostatic process GO:0042592 331 0.013
vesicle mediated transport GO:0016192 181 0.013
positive regulation of gene expression GO:0010628 244 0.012
protein processing GO:0016485 68 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
response to nutrient GO:0007584 248 0.012
secretion GO:0046903 307 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
single organism cellular localization GO:1902580 102 0.012
response to growth factor GO:0070848 189 0.012
cell growth GO:0016049 104 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
response to acid chemical GO:0001101 222 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
regulation of homeostatic process GO:0032844 101 0.012
response to external biotic stimulus GO:0043207 221 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
centrosome cycle GO:0007098 1 0.012
neuronal action potential GO:0019228 35 0.012
negative regulation of cell communication GO:0010648 158 0.011
secretion by cell GO:0032940 248 0.011
regulation of ion transport GO:0043269 245 0.011
mapk cascade GO:0000165 140 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
regulation of hydrolase activity GO:0051336 143 0.011
muscle system process GO:0003012 115 0.011
negative regulation of signaling GO:0023057 157 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
regulation of immunoglobulin production GO:0002637 4 0.011
cell cell signaling GO:0007267 335 0.011
spermatogenesis GO:0007283 99 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
regulation of kinase activity GO:0043549 117 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
chemical homeostasis GO:0048878 292 0.011
ion homeostasis GO:0050801 212 0.011
regulation of catabolic process GO:0009894 113 0.011
regulation of hormone levels GO:0010817 187 0.011
developmental growth GO:0048589 100 0.011
cellular chemical homeostasis GO:0055082 247 0.011
organic anion transport GO:0015711 132 0.011
aromatic compound catabolic process GO:0019439 168 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
metal ion transport GO:0030001 289 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
cellular response to organonitrogen compound GO:0071417 197 0.010
aging GO:0007568 241 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
regulation of blood circulation GO:1903522 110 0.010
regulation of cell growth GO:0001558 85 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
male gamete generation GO:0048232 99 0.010
regulation of locomotion GO:0040012 148 0.010

Leo1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.021
disease of anatomical entity DOID:7 0 0.021
disease of metabolism DOID:0014667 0 0.012
musculoskeletal system disease DOID:17 0 0.011
central nervous system disease DOID:331 0 0.010