Rattus norvegicus

7 known processes

Pmpca

peptidase (mitochondrial processing) alpha

(Aliases: MGC93916)

Pmpca biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxidation reduction process GO:0055114 304 0.134
cellular catabolic process GO:0044248 295 0.115
organic acid metabolic process GO:0006082 292 0.112
cellular macromolecule localization GO:0070727 122 0.100
Yeast
organic substance catabolic process GO:1901575 316 0.091
cellular component assembly GO:0022607 360 0.087
protein complex biogenesis GO:0070271 263 0.079
organelle organization GO:0006996 266 0.075
Yeast
catabolic process GO:0009056 351 0.071
oxoacid metabolic process GO:0043436 290 0.071
intracellular transport GO:0046907 185 0.067
Yeast
reproductive process GO:0022414 372 0.063
nucleoside phosphate metabolic process GO:0006753 283 0.063
cellular component biogenesis GO:0044085 368 0.063
nucleotide metabolic process GO:0009117 279 0.063
regulation of cellular protein metabolic process GO:0032268 267 0.062
positive regulation of cellular component organization GO:0051130 200 0.061
apoptotic process GO:0006915 381 0.061
cellular amino acid metabolic process GO:0006520 107 0.061
regulation of protein metabolic process GO:0051246 289 0.058
single organism catabolic process GO:0044712 283 0.058
macromolecular complex assembly GO:0065003 273 0.057
response to metal ion GO:0010038 253 0.056
programmed cell death GO:0012501 392 0.055
negative regulation of metabolic process GO:0009892 331 0.055
nucleobase containing small molecule metabolic process GO:0055086 316 0.055
carbohydrate derivative metabolic process GO:1901135 346 0.055
macromolecular complex subunit organization GO:0043933 339 0.054
positive regulation of multicellular organismal process GO:0051240 387 0.052
carboxylic acid metabolic process GO:0019752 289 0.049
regulation of phosphate metabolic process GO:0019220 349 0.049
regulation of catalytic activity GO:0050790 304 0.046
protein phosphorylation GO:0006468 345 0.046
protein localization GO:0008104 191 0.045
Yeast
regulation of phosphorus metabolic process GO:0051174 349 0.045
ion transmembrane transport GO:0034220 365 0.045
cellular response to stress GO:0033554 269 0.045
regulation of apoptotic process GO:0042981 335 0.044
single organism intracellular transport GO:1902582 166 0.044
Yeast
ribose phosphate metabolic process GO:0019693 235 0.043
rna biosynthetic process GO:0032774 380 0.042
single organism biosynthetic process GO:0044711 342 0.042
regulation of nervous system development GO:0051960 264 0.041
heterocycle catabolic process GO:0046700 167 0.041
regulation of neurogenesis GO:0050767 247 0.041
negative regulation of cellular metabolic process GO:0031324 281 0.041
organophosphate metabolic process GO:0019637 370 0.040
regulation of catabolic process GO:0009894 113 0.040
macromolecule localization GO:0033036 252 0.039
Yeast
protein complex assembly GO:0006461 263 0.039
transmembrane transport GO:0055085 412 0.038
rna metabolic process GO:0016070 406 0.038
positive regulation of gene expression GO:0010628 244 0.037
protein complex subunit organization GO:0071822 302 0.037
proteolysis GO:0006508 175 0.037
response to inorganic substance GO:0010035 377 0.037
cation transport GO:0006812 382 0.037
regulation of neuron differentiation GO:0045664 208 0.036
nucleobase containing compound catabolic process GO:0034655 152 0.036
cofactor metabolic process GO:0051186 95 0.036
establishment of protein localization GO:0045184 141 0.036
Yeast
regulation of intracellular signal transduction GO:1902531 218 0.036
coenzyme metabolic process GO:0006732 86 0.036
neuron differentiation GO:0030182 368 0.036
single organism reproductive process GO:0044702 297 0.035
sulfur compound metabolic process GO:0006790 70 0.035
organonitrogen compound catabolic process GO:1901565 179 0.034
protein transport GO:0015031 132 0.034
Yeast
cellular amine metabolic process GO:0044106 38 0.034
positive regulation of cell death GO:0010942 184 0.034
organophosphate catabolic process GO:0046434 148 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.034
regulation of protein modification process GO:0031399 194 0.034
protein oligomerization GO:0051259 191 0.033
reproductive structure development GO:0048608 128 0.033
multicellular organismal reproductive process GO:0048609 233 0.033
regulation of cellular component organization GO:0051128 368 0.032
ribonucleotide metabolic process GO:0009259 231 0.032
regulation of programmed cell death GO:0043067 341 0.032
cellular protein localization GO:0034613 122 0.032
Yeast
regulation of cellular catabolic process GO:0031329 101 0.032
single organism cellular localization GO:1902580 102 0.031
Yeast
response to oxidative stress GO:0006979 186 0.031
response to oxygen levels GO:0070482 265 0.030
regulation of molecular function GO:0065009 398 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
positive regulation of nervous system development GO:0051962 178 0.030
transcription dna templated GO:0006351 377 0.030
aromatic compound catabolic process GO:0019439 168 0.030
neuron projection development GO:0031175 273 0.030
nucleoside phosphate catabolic process GO:1901292 140 0.030
response to growth factor GO:0070848 189 0.030
homeostatic process GO:0042592 331 0.029
purine nucleoside catabolic process GO:0006152 124 0.029
regulation of rna metabolic process GO:0051252 391 0.028
carbohydrate derivative catabolic process GO:1901136 147 0.028
intracellular signal transduction GO:0035556 314 0.028
positive regulation of developmental process GO:0051094 283 0.028
single organism membrane organization GO:0044802 74 0.028
regulation of proteasomal protein catabolic process GO:0061136 4 0.028
response to organophosphorus GO:0046683 102 0.027
carbohydrate derivative biosynthetic process GO:1901137 124 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
chromosome segregation GO:0007059 2 0.027
acetyl coa metabolic process GO:0006084 17 0.027
response to corticosteroid GO:0031960 235 0.027
multicellular organism reproduction GO:0032504 233 0.026
positive regulation of neuron projection development GO:0010976 99 0.026
regulation of hydrolase activity GO:0051336 143 0.026
alpha amino acid metabolic process GO:1901605 71 0.026
single organism organelle organization GO:1902589 180 0.026
regulation of cell development GO:0060284 263 0.026
nucleoside catabolic process GO:0009164 126 0.026
purine nucleoside metabolic process GO:0042278 169 0.026
response to nutrient levels GO:0031667 370 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
organic cyclic compound catabolic process GO:1901361 175 0.025
negative regulation of apoptotic process GO:0043066 181 0.025
reproduction GO:0000003 245 0.025
nucleoside metabolic process GO:0009116 179 0.025
positive regulation of rna metabolic process GO:0051254 203 0.025
positive regulation of neurogenesis GO:0050769 165 0.025
purine nucleotide catabolic process GO:0006195 136 0.025
carboxylic acid catabolic process GO:0046395 49 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
positive regulation of programmed cell death GO:0043068 157 0.024
ribonucleotide catabolic process GO:0009261 136 0.024
purine containing compound metabolic process GO:0072521 253 0.024
secretion by cell GO:0032940 248 0.023
negative regulation of cell communication GO:0010648 158 0.023
chemical homeostasis GO:0048878 292 0.023
regulation of cell differentiation GO:0045595 320 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
inorganic ion transmembrane transport GO:0098660 229 0.023
regulation of phosphorylation GO:0042325 248 0.023
protein catabolic process GO:0030163 30 0.023
multi organism reproductive process GO:0044703 262 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
purine nucleotide metabolic process GO:0006163 229 0.023
purine nucleoside triphosphate catabolic process GO:0009146 122 0.023
purine ribonucleoside catabolic process GO:0046130 124 0.022
lipid metabolic process GO:0006629 283 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
purine ribonucleotide catabolic process GO:0009154 136 0.022
locomotion GO:0040011 237 0.022
carboxylic acid transport GO:0046942 115 0.022
central nervous system development GO:0007417 311 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
cellular nitrogen compound catabolic process GO:0044270 163 0.022
response to extracellular stimulus GO:0009991 380 0.022
positive regulation of cell projection organization GO:0031346 111 0.022
cellular ketone metabolic process GO:0042180 51 0.022
nucleic acid templated transcription GO:0097659 379 0.022
nucleoside triphosphate catabolic process GO:0009143 123 0.022
response to temperature stimulus GO:0009266 94 0.022
metal ion transport GO:0030001 289 0.021
response to peptide hormone GO:0043434 278 0.021
reproductive system development GO:0061458 128 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
cell type specific apoptotic process GO:0097285 134 0.021
cell projection organization GO:0030030 302 0.021
hormone transport GO:0009914 121 0.021
negative regulation of cell death GO:0060548 229 0.021
vesicle mediated transport GO:0016192 181 0.021
regulation of signal transduction GO:0009966 318 0.021
positive regulation of transcription dna templated GO:0045893 197 0.021
response to nutrient GO:0007584 248 0.020
cellular amino acid catabolic process GO:0009063 21 0.020
response to alkaloid GO:0043279 132 0.020
regulation of neuron projection development GO:0010975 161 0.020
negative regulation of cellular protein metabolic process GO:0032269 106 0.020
purine containing compound catabolic process GO:0072523 138 0.020
circulatory system process GO:0003013 183 0.020
head development GO:0060322 247 0.020
nucleotide biosynthetic process GO:0009165 98 0.020
regulation of cell projection organization GO:0031344 175 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
regulation of rna biosynthetic process GO:2001141 381 0.020
cell cell signaling GO:0007267 335 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
regulation of transcription dna templated GO:0006355 374 0.020
amine metabolic process GO:0009308 38 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
cofactor biosynthetic process GO:0051188 28 0.020
negative regulation of programmed cell death GO:0043069 183 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
small molecule catabolic process GO:0044282 59 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
developmental process involved in reproduction GO:0003006 159 0.019
membrane organization GO:0061024 94 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
response to ethanol GO:0045471 162 0.019
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
ribose phosphate biosynthetic process GO:0046390 87 0.019
macromolecule catabolic process GO:0009057 58 0.019
glycosyl compound catabolic process GO:1901658 126 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
regulation of system process GO:0044057 208 0.019
negative regulation of protein metabolic process GO:0051248 114 0.018
negative regulation of signaling GO:0023057 157 0.018
brain development GO:0007420 247 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
monosaccharide metabolic process GO:0005996 61 0.018
protein localization to organelle GO:0033365 57 0.018
Yeast
negative regulation of molecular function GO:0044092 133 0.018
glycosyl compound metabolic process GO:1901657 182 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
response to lipopolysaccharide GO:0032496 191 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
cellular chemical homeostasis GO:0055082 247 0.017
neuron development GO:0048666 286 0.017
response to peptide GO:1901652 292 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
peptidyl amino acid modification GO:0018193 126 0.017
negative regulation of gene expression GO:0010629 199 0.017
positive regulation of cell development GO:0010720 176 0.017
cell cycle GO:0007049 101 0.017
ribonucleoside catabolic process GO:0042454 126 0.016
cation homeostasis GO:0055080 195 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
negative regulation of transport GO:0051051 136 0.016
secretion GO:0046903 307 0.016
response to camp GO:0051591 91 0.016
response to purine containing compound GO:0014074 126 0.016
cation transmembrane transport GO:0098655 263 0.016
cytoplasmic transport GO:0016482 115 0.016
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 122 0.016
anion transmembrane transport GO:0098656 77 0.015
organic anion transport GO:0015711 132 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
muscle system process GO:0003012 115 0.015
acyl coa metabolic process GO:0006637 28 0.015
regulation of nucleic acid templated transcription GO:1903506 380 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
gamete generation GO:0007276 124 0.015
neurological system process GO:0050877 219 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
cellular homeostasis GO:0019725 252 0.015
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 4 0.015
positive regulation of neuron differentiation GO:0045666 126 0.015
nucleotide catabolic process GO:0009166 139 0.014
regulation of hormone levels GO:0010817 187 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
synaptic transmission GO:0007268 235 0.014
energy derivation by oxidation of organic compounds GO:0015980 46 0.014
carbohydrate metabolic process GO:0005975 130 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
ion homeostasis GO:0050801 212 0.014
positive regulation of cellular component biogenesis GO:0044089 55 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
organic acid catabolic process GO:0016054 49 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
amide transport GO:0042886 105 0.014
cellular response to oxidative stress GO:0034599 76 0.013
response to cadmium ion GO:0046686 35 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.013
response to hypoxia GO:0001666 231 0.013
regulation of secretion GO:0051046 224 0.013
ribonucleoside diphosphate metabolic process GO:0009185 10 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
regulation of kinase activity GO:0043549 117 0.013
response to biotic stimulus GO:0009607 226 0.013
regulation of cellular localization GO:0060341 263 0.013
aging GO:0007568 241 0.013
regulation of membrane potential GO:0042391 110 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
blood circulation GO:0008015 183 0.013
intracellular protein transport GO:0006886 79 0.013
Yeast
response to ketone GO:1901654 182 0.013
nicotinamide nucleotide metabolic process GO:0046496 28 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
mitotic cell cycle GO:0000278 49 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.013
multi multicellular organism process GO:0044706 138 0.012
posttranscriptional regulation of gene expression GO:0010608 37 0.012
regulation of cell proliferation GO:0042127 359 0.012
response to decreased oxygen levels GO:0036293 237 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
regulation of neuron apoptotic process GO:0043523 83 0.012
negative regulation of protein modification process GO:0031400 52 0.012
sexual reproduction GO:0019953 148 0.012
multicellular organism growth GO:0035264 1 0.012
nucleoside monophosphate biosynthetic process GO:0009124 28 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
maintenance of location GO:0051235 17 0.012
positive regulation of catabolic process GO:0009896 78 0.012
hexose metabolic process GO:0019318 58 0.012
positive regulation of cell communication GO:0010647 271 0.012
metal ion homeostasis GO:0055065 186 0.012
regulation of response to stress GO:0080134 126 0.012
positive regulation of signaling GO:0023056 270 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
calcium ion transport GO:0006816 131 0.012
anion transport GO:0006820 178 0.012
rhythmic process GO:0048511 156 0.012
response to acid chemical GO:0001101 222 0.012
protein targeting GO:0006605 61 0.012
Yeast
spindle organization GO:0007051 2 0.011
protein processing GO:0016485 68 0.011
Yeast
positive regulation of transcription elongation from rna polymerase ii promoter GO:0032968 3 0.011
male gamete generation GO:0048232 99 0.011
female pregnancy GO:0007565 122 0.011
organic acid transport GO:0015849 116 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
protein tetramerization GO:0051262 38 0.011
cellular response to endogenous stimulus GO:0071495 377 0.011
cognition GO:0050890 92 0.011
cell adhesion GO:0007155 110 0.011
thioester biosynthetic process GO:0035384 7 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.011
ras protein signal transduction GO:0007265 29 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
pyridine containing compound metabolic process GO:0072524 32 0.011
cellular lipid metabolic process GO:0044255 208 0.011
eye morphogenesis GO:0048592 4 0.011
axis specification GO:0009798 4 0.011
nucleoside monophosphate catabolic process GO:0009125 56 0.011
nitrogen compound transport GO:0071705 229 0.011
response to vitamin GO:0033273 131 0.011
peptide transport GO:0015833 97 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
regeneration GO:0031099 163 0.011
regulation of neuron death GO:1901214 115 0.011
development of primary sexual characteristics GO:0045137 107 0.011
positive regulation of signal transduction GO:0009967 175 0.011
heart contraction GO:0060047 57 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.010
peptide metabolic process GO:0006518 32 0.010
response to toxic substance GO:0009636 133 0.010
heart morphogenesis GO:0003007 3 0.010
cellular cation homeostasis GO:0030003 180 0.010
transmission of nerve impulse GO:0019226 42 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
regulation of cellular response to stress GO:0080135 49 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
positive regulation of phosphorylation GO:0042327 177 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
gastrulation GO:0007369 2 0.010
response to radiation GO:0009314 137 0.010
regulation of proteolysis GO:0030162 66 0.010
purine nucleoside diphosphate metabolic process GO:0009135 9 0.010
glycogen metabolic process GO:0005977 23 0.010
response to external biotic stimulus GO:0043207 221 0.010
cellular amide metabolic process GO:0043603 44 0.010

Pmpca disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
nervous system disease DOID:863 0 0.032
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.014
central nervous system disease DOID:331 0 0.014
carbohydrate metabolic disorder DOID:2978 0 0.013