Rattus norvegicus

5 known processes

Akr7a2

aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)

(Aliases: Aiar)

Akr7a2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tetrapyrrole metabolic process GO:0033013 11 0.279
porphyrin containing compound metabolic process GO:0006778 8 0.185
tetrapyrrole biosynthetic process GO:0033014 7 0.170
cofactor metabolic process GO:0051186 95 0.118
monocarboxylic acid metabolic process GO:0032787 152 0.116
organic acid metabolic process GO:0006082 292 0.087
cofactor biosynthetic process GO:0051188 28 0.068
porphyrin containing compound biosynthetic process GO:0006779 6 0.068
heme biosynthetic process GO:0006783 4 0.056
alpha amino acid biosynthetic process GO:1901607 23 0.055
positive regulation of glycolytic process GO:0045821 5 0.047
response to vitamin e GO:0033197 24 0.047
head development GO:0060322 247 0.045
response to glucocorticoid GO:0051384 223 0.043
response to corticosteroid GO:0031960 235 0.043
oxoacid metabolic process GO:0043436 290 0.042
response to platinum ion GO:0070541 4 0.041
response to cobalt ion GO:0032025 12 0.041
organonitrogen compound biosynthetic process GO:1901566 167 0.041
protein complex biogenesis GO:0070271 263 0.040
protein complex assembly GO:0006461 263 0.038
response to nutrient GO:0007584 248 0.033
single organism carbohydrate catabolic process GO:0044724 40 0.030
cellular response to endogenous stimulus GO:0071495 377 0.029
protein phosphorylation GO:0006468 345 0.028
response to vitamin GO:0033273 131 0.028
fatty acid beta oxidation GO:0006635 22 0.027
cellular modified amino acid biosynthetic process GO:0042398 18 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
positive regulation of response to stimulus GO:0048584 285 0.027
single organism reproductive process GO:0044702 297 0.026
hair follicle development GO:0001942 2 0.026
response to dexamethasone GO:0071548 49 0.026
cellular response to corticosteroid stimulus GO:0071384 69 0.025
cation transport GO:0006812 382 0.025
gamete generation GO:0007276 124 0.025
metal ion transport GO:0030001 289 0.024
regulation of molecular function GO:0065009 398 0.024
neuron development GO:0048666 286 0.023
response to decreased oxygen levels GO:0036293 237 0.023
sulfur compound metabolic process GO:0006790 70 0.022
organelle organization GO:0006996 266 0.022
regulation of cellular response to stress GO:0080135 49 0.022
organic acid catabolic process GO:0016054 49 0.021
pentose metabolic process GO:0019321 8 0.021
response to other organism GO:0051707 220 0.020
purine containing compound metabolic process GO:0072521 253 0.020
carboxylic acid metabolic process GO:0019752 289 0.020
response to lipopolysaccharide GO:0032496 191 0.020
neuron differentiation GO:0030182 368 0.020
regulation of neurogenesis GO:0050767 247 0.020
carbohydrate metabolic process GO:0005975 130 0.019
oxidation reduction process GO:0055114 304 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
response to toxic substance GO:0009636 133 0.019
localization of cell GO:0051674 202 0.019
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.019
ion transmembrane transport GO:0034220 365 0.019
protein complex subunit organization GO:0071822 302 0.019
cell cycle GO:0007049 101 0.018
organic substance catabolic process GO:1901575 316 0.018
Rat
central nervous system development GO:0007417 311 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
single organism carbohydrate metabolic process GO:0044723 118 0.018
brain development GO:0007420 247 0.017
positive regulation of cell motility GO:2000147 97 0.017
single organism biosynthetic process GO:0044711 342 0.017
response to hypoxia GO:0001666 231 0.017
response to methylmercury GO:0051597 16 0.016
response to amine GO:0014075 46 0.016
response to estrogen GO:0043627 232 0.016
ion homeostasis GO:0050801 212 0.016
cellular response to stress GO:0033554 269 0.016
multicellular organismal reproductive process GO:0048609 233 0.015
programmed cell death GO:0012501 392 0.015
response to lead ion GO:0010288 33 0.015
response to ketone GO:1901654 182 0.015
response to inorganic substance GO:0010035 377 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
reproduction GO:0000003 245 0.014
regulation of neuron projection development GO:0010975 161 0.014
neuron projection development GO:0031175 273 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
response to peptide GO:1901652 292 0.014
transmembrane transport GO:0055085 412 0.014
blood circulation GO:0008015 183 0.014
intracellular signal transduction GO:0035556 314 0.014
nucleoside metabolic process GO:0009116 179 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
potassium ion transport GO:0006813 97 0.014
cellular chemical homeostasis GO:0055082 247 0.014
apoptotic process GO:0006915 381 0.014
cellular homeostasis GO:0019725 252 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
microtubule organizing center organization GO:0031023 1 0.014
regulation of neurotransmitter levels GO:0001505 42 0.013
cation homeostasis GO:0055080 195 0.013
macromolecular complex assembly GO:0065003 273 0.013
fatty acid metabolic process GO:0006631 99 0.013
cellular response to oxygen containing compound GO:1901701 386 0.013
regulation of protein kinase activity GO:0045859 105 0.013
brain renin angiotensin system GO:0002035 3 0.013
cellular cation homeostasis GO:0030003 180 0.013
metal ion homeostasis GO:0055065 186 0.013
response to estradiol GO:0032355 164 0.013
cell motility GO:0048870 202 0.013
regulation of response to stress GO:0080134 126 0.012
protein oligomerization GO:0051259 191 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
neuron neuron synaptic transmission GO:0007270 60 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
regulation of cell differentiation GO:0045595 320 0.012
reproductive process GO:0022414 372 0.012
monosaccharide metabolic process GO:0005996 61 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
axis specification GO:0009798 4 0.012
hair cycle process GO:0022405 2 0.012
regulation of protein phosphorylation GO:0001932 183 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
response to mercury ion GO:0046689 15 0.011
regulation of defense response GO:0031347 68 0.011
cellular response to lipid GO:0071396 201 0.011
sexual reproduction GO:0019953 148 0.011
cellular ketone metabolic process GO:0042180 51 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
positive regulation of signaling GO:0023056 270 0.011
axon development GO:0061564 96 0.011
macromolecule localization GO:0033036 252 0.011
regulation of cell development GO:0060284 263 0.011
estrogen biosynthetic process GO:0006703 6 0.011
centrosome cycle GO:0007098 1 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
response to external biotic stimulus GO:0043207 221 0.011
spermatogenesis GO:0007283 99 0.011
pigment biosynthetic process GO:0046148 4 0.011
embryonic pattern specification GO:0009880 1 0.011
carbohydrate catabolic process GO:0016052 40 0.011
halogenated hydrocarbon metabolic process GO:0042197 4 0.011
male gamete generation GO:0048232 99 0.011
organonitrogen compound catabolic process GO:1901565 179 0.010
hormone metabolic process GO:0042445 69 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
monovalent inorganic cation transport GO:0015672 172 0.010
regulation of cellular amino acid metabolic process GO:0006521 2 0.010
developmental process involved in reproduction GO:0003006 159 0.010
cellular component assembly GO:0022607 360 0.010
cell migration GO:0016477 197 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010

Akr7a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.027
inherited metabolic disorder DOID:655 0 0.027
amino acid metabolic disorder DOID:9252 0 0.023
organic acidemia DOID:0060159 0 0.023
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012